This is a selection of articles from the December 2006 archive. Click here for this month's Internal Medicine headlines.
Oxidative-stress and IL-6 mediate the fibrogenic effects of Kupffer cells on stellate cells
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Source: Hepatology - December 30, 2006 Source Type: journals
Effect of tumor necrosis factor [alpha] on electrically induced calcium transients elicited in C2C12 skeletal myotubes
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Source: Muscle - December 28, 2006 Authors: Lisa N. van Kann, Anthony J. Bakker Source Type: journals
Multidrug-Resistant TB in the Philippines: Totem and Taboo
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Source: PLoS Medicine - December 27, 2006 Source Type: journals
Enrolling Adolescents in Research on HIV: Young Women Must Be Included
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Source: PLoS Medicine - December 27, 2006 Source Type: journals
Do We Need a World Health Insurance to Realise the Right to Health?
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Source: PLoS Medicine - December 27, 2006 Source Type: journals
A Genome-Wide Screen for Promoter Methylation in Lung Cancer Identifies Novel Methylation Markers for Multiple Malignancies
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Source: PLoS Medicine - December 27, 2006 Source Type: journals
Vaccine Efficacy in Senescent Mice Challenged with Recombinant SARS-CoV Bearing Epidemic and Zoonotic Spike Variants
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Source: PLoS Medicine - December 27, 2006 Source Type: journals
Antibodies and Brain Disease: A Convergence of Immunology and Physiology
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Source: PLoS Medicine - December 27, 2006 Source Type: journals
Tuberculosis among Health-Care Workers in Low- and Middle-Income Countries: A Systematic Review
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Source: PLoS Medicine - December 27, 2006 Source Type: journals
TV Viewing and Physical Activity Are Independently Associated with Metabolic Risk in Children: The European Youth Heart Study
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Source: PLoS Medicine - December 27, 2006 Source Type: journals
TV and Inactivity Are Separate Contributors to Metabolic Risk Factors in Children
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Source: PLoS Medicine - December 27, 2006 Source Type: journals
HIV-1 Viral Load Assays for Resource-Limited Settings: Authors' Reply
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Source: PLoS Medicine - December 27, 2006 Source Type: journals
Drug Development Papers in PLoS Medicine: How We Try to Spot a Winner
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Source: PLoS Medicine - December 27, 2006 Source Type: journals
Blinding Trachoma in Postconflict Southern Sudan
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Source: PLoS Medicine - December 27, 2006 Source Type: journals
Hypogammaglobulinemia with Facial Edema
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Source: PLoS Medicine - December 27, 2006 Source Type: journals
Correction: Eight Americas: Investigating Mortality Disparities across Races, Counties, and Race-Counties in the United States
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Source: PLoS Medicine - December 27, 2006 Source Type: journals
Erythrocyte G Protein as a Novel Target for Malarial Chemotherapy
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Source: PLoS Medicine - December 27, 2006 Source Type: journals
Prevalence and Causes of Blindness and Low Vision in Southern Sudan
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Source: PLoS Medicine - December 27, 2006 Source Type: journals
Cost-Effectiveness of Male Circumcision for HIV Prevention in a South African Setting
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Source: PLoS Medicine - December 27, 2006 Source Type: journals
Multidrug-Resistant TB in the Philippines: Authors' Reply
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Source: PLoS Medicine - December 27, 2006 Source Type: journals
Intensive Insulin Therapy in Intensive Care: An Example of the Struggle to Implement Evidence-Based Medicine
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Source: PLoS Medicine - December 27, 2006 Source Type: journals
Elevated Serum Levels of Interferon-Regulated Chemokines Are Biomarkers for Active Human Systemic Lupus Erythematosus
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Source: PLoS Medicine - December 27, 2006 Source Type: journals
Lack of Mucosal Immune Reconstitution during Prolonged Treatment of Acute and Early HIV-1 Infection
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Source: PLoS Medicine - December 27, 2006 Source Type: journals
Impact of Extended-Duration Shifts on Medical Errors, Adverse Events, and Attentional Failures
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Source: PLoS Medicine - December 27, 2006 Source Type: journals
The Malaria Atlas Project: Developing Global Maps of Malaria Risk
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Source: PLoS Medicine - December 27, 2006 Source Type: journals
Angiotensin-Converting Enzyme I/D Polymorphism and Preeclampsia Risk: Evidence of Small-Study Bias
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Source: PLoS Medicine - December 27, 2006 Source Type: journals
HIV-1 Viral Load Assays for Resource-Limited Settings: Clades Matter
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Source: PLoS Medicine - December 27, 2006 Source Type: journals
Lipoprotein Particle Profiles Mark Familial and Sporadic Human Longevity
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Source: PLoS Medicine - December 27, 2006 Source Type: journals
Impaired Hepatitis C Virus-Specific T Cell Responses and Recurrent Hepatitis C Virus in HIV Coinfection
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Source: PLoS Medicine - December 27, 2006 Source Type: journals
ORIGINAL ARTICLE: An Intervention to Decrease Catheter-Related Bloodstream Infections in the ICU
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Source: New England Journal of Medicine - December 27, 2006 Authors: Pronovost, P., Needham, D., Berenholtz, S., Sinopoli, D., Chu, H., Cosgrove, S., Sexton, B., Hyzy, R., Welsh, R., Roth, G., Bander, J., Kepros, J., Goeschel, C. Source Type: journals
CORRESPONDENCE: Effects of Dietary Nitrate on Blood Pressure in Healthy Volunteers
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Source: New England Journal of Medicine - December 27, 2006 Authors: Larsen, F. J., Ekblom, B., Sahlin, K., Lundberg, J. O., Weitzberg, E. Source Type: journals
CORRESPONDENCE: Echinocandins for Candidemia
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Source: New England Journal of Medicine - December 27, 2006 Authors: Garcia-Vidal, C., Carratala, J., Bennett, J. E. Source Type: journals
CASE RECORDS OF THE MASSACHUSETTS GENERAL HOSPITAL: Case 40-2006 -- A 64-Year-Old Man with Anemia and a Low Level of HDL Cholesterol
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Source: New England Journal of Medicine - December 27, 2006 Authors: Murali, M. R., Kratz, A., Finberg, K. E. Source Type: journals
BOOK REVIEW: Reconceiving the Gene: Seymour Benzer's Adventures in Phage Genetics
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Source: New England Journal of Medicine - December 27, 2006 Authors: Weiner, J. Source Type: journals
CORRECTIONS: Acute Vulvovaginitis
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Source: New England Journal of Medicine - December 27, 2006 Source Type: journals
ORIGINAL ARTICLE: Female Predominance and Transmission Distortion in the Long-QT Syndrome
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Source: New England Journal of Medicine - December 27, 2006 Authors: Imboden, M., Swan, H., Denjoy, I., Van Langen, I. M., Latinen-Forsblom, P. J., Napolitano, C., Fressart, V., Breithardt, G., Berthet, M., Priori, S., Hainque, B., Wilde, A. A. M., Schulze-Bahr, E., Feingold, J., Guicheney, P. Source Type: journals
ORIGINAL ARTICLE: Brief Report: Human Trypanosoma evansi Infection Linked to a Lack of Apolipoprotein L-I
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Source: New England Journal of Medicine - December 27, 2006 Authors: Vanhollebeke, B., Truc, P., Poelvoorde, P., Pays, A., Joshi, P. P., Katti, R., Jannin, J. G., Pays, E. Source Type: journals
BOOK REVIEW: Molecular Mechanisms of Cardiac Hypertrophy and Failure
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Source: New England Journal of Medicine - December 27, 2006 Authors: Feldman, A. M. Source Type: journals
PERSPECTIVE: Uncovering an Epidemic -- Screening for Mental Illness in Teens
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Source: New England Journal of Medicine - December 27, 2006 Authors: Friedman, R. A. Source Type: journals
ORIGINAL ARTICLE: Lapatinib plus Capecitabine for HER2-Positive Advanced Breast Cancer
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Source: New England Journal of Medicine - December 27, 2006 Authors: Geyer, C. E., Forster, J., Lindquist, D., Chan, S., Romieu, C. G., Pienkowski, T., Jagiello-Gruszfeld, A., Crown, J., Chan, A., Kaufman, B., Skarlos, D., Campone, M., Davidson, N., Berger, M., Oliva, C., Rubin, S. D., Stein, S., Cameron, D. Source Type: journals
IMAGES IN CLINICAL MEDICINE: Benign Diffuse Breast Hyperplasia during Pregnancy
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Source: New England Journal of Medicine - December 27, 2006 Authors: Pasrija, S., Sharma, N. Source Type: journals
EDITORIAL: Team-Based Prevention of Catheter-Related Infections
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Source: New England Journal of Medicine - December 27, 2006 Authors: Wenzel, R. P., Edmond, M. B. Source Type: journals
CME: Lapatinib plus Capecitabine for HER2-Positive Advanced Breast Cancer
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Source: New England Journal of Medicine - December 27, 2006 Source Type: journals
EDITORIAL: Targeted Therapy for Metastatic Breast Cancer
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Source: New England Journal of Medicine - December 27, 2006 Authors: Muss, H. B. Source Type: journals
CME: An Intervention to Decrease Catheter-Related Bloodstream Infections in the ICU
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Source: New England Journal of Medicine - December 27, 2006 Source Type: journals
CORRESPONDENCE: Acute Vulvovaginitis
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Source: New England Journal of Medicine - December 27, 2006 Authors: Shirley, R. L., Eckert, L. O. Source Type: journals
ORIGINAL ARTICLE: Brief Report: Deficiency of Cartilage-Associated Protein in Recessive Lethal Osteogenesis Imperfecta
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Source: New England Journal of Medicine - December 27, 2006 Authors: Barnes, A. M., Chang, W., Morello, R., Cabral, W. A., Weis, M., Eyre, D. R., Leikin, S., Makareeva, E., Kuznetsova, N., Uveges, T. E., Ashok, A., Flor, A. W., Mulvihill, J. J., Wilson, P. L., Sundaram, U. T., Lee, B., Marini, J. C. Source Type: journals
Dynamic DCs of the gut
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Source: The Journal of Experimental Medicine - December 26, 2006 Authors: Williams, R. Source Type: journals
A bacterial carbohydrate links innate and adaptive responses through Toll-like receptor 2
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Source: The Journal of Experimental Medicine - December 26, 2006 Authors: Wang, Q., McLoughlin, R. M., Cobb, B. A., Charrel-Dennis, M., Zaleski, K. J., Golenbock, D., Tzianabos, A. O., Kasper, D. L. Source Type: journals
Neutrophil histamine contributes to inflammation in mycoplasma pneumonia
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Source: The Journal of Experimental Medicine - December 26, 2006 Authors: Xu, X., Zhang, D., Zhang, H., Wolters, P. J., Killeen, N. P., Sullivan, B. M., Locksley, R. M., Lowell, C. A., Caughey, G. H. Source Type: journals
Bcl-xl does not have to bind Bax to protect T cells from death
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Source: The Journal of Experimental Medicine - December 26, 2006 Authors: Liu, X., Zhu, Y., Dai, S., White, J., Peyerl, F., Kappler, J. W., Marrack, P. Source Type: journals
Position of power
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Source: The Journal of Experimental Medicine - December 26, 2006 Authors: Williams, R. Source Type: journals
Caveolin-1: a critical regulator of lung fibrosis in idiopathic pulmonary fibrosis
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Source: The Journal of Experimental Medicine - December 26, 2006 Authors: Wang, X. M., Zhang, Y., Kim, H. P., Zhou, Z., Feghali-Bostwick, C. A., Liu, F., Ifedigbo, E., Xu, X., Oury, T. D., Kaminski, N., Choi, A. M.K. Source Type: journals
Puma cooperates with Bim, the rate-limiting BH3-only protein in cell death during lymphocyte development, in apoptosis induction
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Source: The Journal of Experimental Medicine - December 26, 2006 Authors: Erlacher, M., Labi, V., Manzl, C., Bock, G., Tzankov, A., Hacker, G., Michalak, E., Strasser, A., Villunger, A. Source Type: journals
Orchestration of lymphocyte chemotaxis by mitochondrial dynamics
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Source: The Journal of Experimental Medicine - December 26, 2006 Authors: Campello, S., Lacalle, R. A., Bettella, M., Manes, S., Scorrano, L., Viola, A. Source Type: journals
CORRECTION
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Source: The Journal of Experimental Medicine - December 26, 2006 Authors: Peng, G., Lei, K. J., Jin, W., Greenwell-Wild, T., Wahl, S. M. Source Type: journals
Cardiotrophin-1 defends the liver against ischemia-reperfusion injury and mediates the protective effect of ischemic preconditioning
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Source: The Journal of Experimental Medicine - December 26, 2006 Authors: Iniguez, M., Berasain, C., Martinez-Anso, E., Bustos, M., Fortes, P., Pennica, D., Avila, M. A., Prieto, J. Source Type: journals
The G534E polymorphism of the gene encoding the factor VII-activating protease is associated with cardiovascular risk due to increased neointima formation
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Source: The Journal of Experimental Medicine - December 26, 2006 Authors: Sedding, D., Daniel, J.-M., Muhl, L., Hersemeyer, K., Brunsch, H., Kemkes-Matthes, B., Braun-Dullaeus, R. C., Tillmanns, H., Weimer, T., Preissner, K. T., Kanse, S. M. Source Type: journals
APOBEC3G/3F mediates intrinsic resistance of monocyte-derived dendritic cells to HIV-1 infection
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Source: The Journal of Experimental Medicine - December 26, 2006 Authors: Pion, M., Granelli-Piperno, A., Mangeat, B., Stalder, R., Correa, R., Steinman, R. M., Piguet, V. Source Type: journals
FSAP reduces risk of repair
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Source: The Journal of Experimental Medicine - December 26, 2006 Authors: Williams, R. Source Type: journals
Deregulated Syk inhibits differentiation and induces growth factor-independent proliferation of pre-B cells
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Source: The Journal of Experimental Medicine - December 26, 2006 Authors: Wossning, T., Herzog, S., Kohler, F., Meixlsperger, S., Kulathu, Y., Mittler, G., Abe, A., Fuchs, U., Borkhardt, A., Jumaa, H. Source Type: journals
Summaries for patients. Complications of colonoscopy.
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Source: Ann Intern Med - December 22, 2006 Source Type: journals
A randomized trial of alternative medicines for vasomotor symptoms of menopause.
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Source: Ann Intern Med - December 22, 2006 Source Type: journals
Summaries for patients. Treating symptoms of menopause: a study of the effectiveness of black cohosh alone and with other herbal therapies or soy.
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Source: Ann Intern Med - December 22, 2006 Source Type: journals
Complications of colonoscopy in an integrated health care delivery system.
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Source: Ann Intern Med - December 22, 2006 Source Type: journals
The Coming of Age of Multicultural Medicine
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Source: PLoS Medicine - December 21, 2006 Source Type: journals
Recurrent Pleural and Pericardial Effusions Due to Sarcoidosis
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Source: PLoS Medicine - December 21, 2006 Source Type: journals
Designing an Equitable Strategy for Allocating Antiretroviral Treatments
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Source: PLoS Medicine - December 21, 2006 Source Type: journals
Authors' Reply
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Source: PLoS Medicine - December 21, 2006 Source Type: journals
Accounting for Individual Differences in Risk of Alzheimer Disease
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Source: PLoS Medicine - December 21, 2006 Source Type: journals
How Does PLoS Medicine Manage Competing Interests?
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Source: PLoS Medicine - December 21, 2006 Source Type: journals
Acquired Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib Is Associated with a Second Mutation in the EGFR Kinase Domain
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Source: PLoS Medicine - December 21, 2006 Source Type: journals
Serum Uric Acid and Coronary Heart Disease in 9,458 Incident Cases and 155,084 Controls: Prospective Study and Meta-Analysis