This is a selection of articles from the February 2007 archive. Click here for this month's Molecular Biology headlines.
SIRT1 promotes DNA repair activity and deacetylation of Ku70.
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Source: exp Mol Med - February 28, 2007 Authors: Jeong J, Juhn K, Lee H, Kim SH, Min BH, Lee KM, Cho MH, Park GH, Lee KH Tags: Exp Mol Med Source Type: news
STP-A11, an oncoprotein of Herpesvirus saimiri augments both NF-kappaB and AP-1 transcription activity through TRAF6.
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Source: exp Mol Med - February 28, 2007 Authors: Jeong S, Cho IR, An WG, Jhun BH, Lee B, Park K, Chung YH Tags: Exp Mol Med Source Type: news
Psammaplin A is a natural prodrug that inhibits class I histone deacetylase.
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Source: exp Mol Med - February 28, 2007 Authors: Kim DH, Shin J, Kwon HJ Tags: Exp Mol Med Source Type: news
TNF-alpha upregulates PTEN via NF-kappaB signaling pathways in human leukemic cells.
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Source: exp Mol Med - February 28, 2007 Authors: Lee YR, Yu HN, Noh EM, Youn HJ, Song EK, Han MK, Park CS, Kim BS, Park YS, Park BK, Lee SH, Kim JS Tags: Exp Mol Med Source Type: news
alpha-Lipoic acid inhibits matrix metalloproteinase-9 expression by inhibiting NF-kappaB transcriptional activity.
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Source: exp Mol Med - February 28, 2007 Authors: Kim HS, Kim HJ, Park KG, Kim YN, Kwon TK, Park JY, Lee KU, Kim JG, Lee IK Tags: Exp Mol Med Source Type: news
The coding/non-coding overlapping architecture of the gene encoding the Drosophila pseudouridine synthase
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Source: BMC Molecular Biology - Latest articles - February 28, 2007 Authors: Sara Riccardo, Giuseppe Tortoriello, Ennio Giordano, Mimmo Turano and Maria Furia Source Type: news
Coordinated change of a ratio of methylated H3-Iysine 4 or acetylated H3 to acetylated H4 and DNA methylation is associated with tissue-specific gene expression in cloned pig.
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Source: exp Mol Med - February 28, 2007 Authors: Kang JK, Park KW, Chung YG, You JS, Kim YK, Lee SH, Hong SP, Choi KM, Heo KN, Seol JG, Lee JH, Jin DI, Park CS, Seo JS, Lee HW, Han JW Tags: Exp Mol Med Source Type: news
Synthesis of densely functionalised arenes using [2 + 2 + 2] cycloaddition reactions
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Source: RSC - Organic Biomolecular Chemistry - February 27, 2007 Authors: Jonathan ClaydenWesley J. Moran Source Type: news
Multilocus Analysis of Nucleotide Variation of Oryza sativa and Its Wild Relatives: Severe Bottleneck during Domestication of Rice
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Source: Molecular Biology and Evolution - February 27, 2007 Authors: Zhu, Q., Zheng, X., Luo, J., Gaut, B. S., Ge, S. Tags: Research Articles Source Type: news
Gene Expression and Protein Length Influence Codon Usage and Rates of Sequence Evolution in Populus tremula
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Source: Molecular Biology and Evolution - February 27, 2007 Authors: Ingvarsson, P. K. Tags: Research Articles Source Type: news
Divergent Haplotypes and Human History as Revealed in a Worldwide Survey of X-Linked DNA Sequence Variation
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Source: Molecular Biology and Evolution - February 27, 2007 Authors: Shimada, M. K., Panchapakesan, K., Tishkoff, S. A., Nato, A. Q., Hey, J. Tags: Research Articles Source Type: news
Phylogenetic Analyses of Nuclear, Mitochondrial, and Plastid Multigene Data Sets Support the Placement of Mesostigma in the Streptophyta
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Source: Molecular Biology and Evolution - February 27, 2007 Authors: Rodriguez-Ezpeleta, N., Philippe, H., Brinkmann, H., Becker, B., Melkonian, M. Tags: Research Articles Source Type: news
Rearrangement Rate following the Whole-Genome Duplication in Teleosts
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Source: Molecular Biology and Evolution - February 27, 2007 Authors: Semon, M., Wolfe, K. H. Tags: Research Articles Source Type: news
Genetic Evidence for the Convergent Evolution of Light Skin in Europeans and East Asians
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Source: Molecular Biology and Evolution - February 27, 2007 Authors: Norton, H. L., Kittles, R. A., Parra, E., McKeigue, P., Mao, X., Cheng, K., Canfield, V. A., Bradley, D. G., McEvoy, B., Shriver, M. D. Tags: Research Articles Source Type: news
Drosophila mojoless, a Retroposed GSK-3, Has Functionally Diverged to Acquire an Essential Role in Male Fertility
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Source: Molecular Biology and Evolution - February 27, 2007 Authors: Kalamegham, R., Sturgill, D., Siegfried, E., Oliver, B. Tags: Research Articles Source Type: news
ICAM-1 expression on conjunctival epithelial cells in patients with cystic fibrosis
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Source: Cytometry Part B: Clinical Cytometry - February 27, 2007 Authors: Malgorzata Mrugacz, Janusz Zak, Alina Bakunowicz-Lazarczyk, Jolanta Wysocka, Maciej Kaczmarski Source Type: news
Toll-Like Receptors Are Part of the Innate Immune Defense System of Sponges (Demospongiae: Porifera)
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Source: Molecular Biology and Evolution - February 27, 2007 Authors: Wiens, M., Korzhev, M., Perovic-Ottstadt, S., Luthringer, B., Brandt, D., Klein, S., Muller, W. E. G. Tags: Research Articles Source Type: news
The Mitochondrial Genome of the Moss Physcomitrella patens Sheds New Light on Mitochondrial Evolution in Land Plants
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Source: Molecular Biology and Evolution - February 27, 2007 Authors: Terasawa, K., Odahara, M., Kabeya, Y., Kikugawa, T., Sekine, Y., Fujiwara, M., Sato, N. Tags: Research Articles Source Type: news
Evidence of Interaction Network Evolution by Whole-Genome Duplications: A Case Study in MADS-Box Proteins
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Source: Molecular Biology and Evolution - February 27, 2007 Authors: Veron, A. S., Kaufmann, K., Bornberg-Bauer, E. Tags: Research Articles Source Type: news
Phylogenetic Evidence for Deleterious Mutation Load in RNA Viruses and Its Contribution to Viral Evolution
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Source: Molecular Biology and Evolution - February 27, 2007 Authors: Pybus, O. G., Rambaut, A., Belshaw, R., Freckleton, R. P., Drummond, A. J., Holmes, E. C. Tags: Research Articles Source Type: news
Phylogenetic Methodology for Detecting Protein Interactions
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Source: Molecular Biology and Evolution - February 27, 2007 Authors: Waddell, P. J., Kishino, H., Ota, R. Tags: Research Articles Source Type: news
Not Born Equal: Increased Rate Asymmetry in Relocated and Retrotransposed Rodent Gene Duplicates
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Source: Molecular Biology and Evolution - February 27, 2007 Authors: Cusack, B. P., Wolfe, K. H. Tags: Research Articles Source Type: news
Whole-mtDNA Genome Sequence Analysis of Ancient African Lineages
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Source: Molecular Biology and Evolution - February 27, 2007 Authors: Gonder, M. K., Mortensen, H. M., Reed, F. A., de Sousa, A., Tishkoff, S. A. Tags: Research Articles Source Type: news
The evolutionary history of Cytochrome P450 genes in four filamentous Ascomycetes
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Source: BMC Evolutionary Biology - Latest articles - February 26, 2007 Authors: Jixin Deng, Ignazio Carbone and Ralph A Dean Source Type: news
Selection of reliable reference genes for qPCR studies on chondroprotective action
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Source: BMC Molecular Biology - Latest articles - February 26, 2007 Authors: Stefan Toegel, Wenwen Huang, Claudia Piana, Frank M Unger, Michael Wirth, Mary B Goldring, Franz Gabor and Helmut Viernstein Source Type: news
Molecular mechanisms mediating the G protein-coupled receptor regulation of cell cycle progression
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Source: Journal of Molecular Signaling - February 26, 2007 Authors: David C New and Yung H Wong Source Type: news
Expression of Sox9, Mis, and Dmrt1 in the gonad of a species with temperature-dependent sex determination
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Source: Developmental Dynamics - February 26, 2007 Authors: Christina Shoemaker, Mary Ramsey, Joanna Queen, David Crews Source Type: news
Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit
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Source: Nature Structural and Molecular Biology - February 25, 2007 Authors: Franck TarendeauJulien BoudetDelphine GuilligayPhilippe J MasCatherine M BougaultSébastien BouloFlorence BaudinRob W H RuigrokNathalie DaigleJan EllenbergStephen CusackJean-Pierre SimorreDarren J Hart Tags: Article Source Type: news
Factor B structure provides insights into activation of the central protease of the complement system
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Source: Nature Structural and Molecular Biology - February 25, 2007 Authors: Fin J MilderLucio GomesArie SchoutenBert J C JanssenEric G HuizingaRoland A RomijnWieger HemrikaAnja RoosMohamed R DahaPiet Gros Tags: Article Source Type: news
Development of the retinal vasculature
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Source: Angiogenesis - February 24, 2007 Tags: Angiogenesis Source Type: news
Assessment of Progression and Treatment Response of Optic Pathway Glioma with Positron Emission Tomography using α-[11C]Methyl-l
-Tryptophan
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Source: Molecular Imaging and Biology - February 23, 2007 Tags: Molecular Imaging and Biology Source Type: news
Involvement of nuclear factor-kB activation through RhoA/Rho-kinase pathway in LPS-induced IL-8 production in human cervical stromal cells
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Source: Molecular Human Reproduction - February 23, 2007 Authors: Shimizu, S., Tahara, M., Ogata, S., Hashimoto, K., Morishige, K., Tasaka, K., Murata, Y. Tags: Articles Source Type: news
The effects of oxygen concentration on in vitro output of prostaglandin E2 and interleukin-6 from human fetal membranes
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Source: Molecular Human Reproduction - February 23, 2007 Authors: Al-Asmakh, M., Race, H., Tan, S., Sullivan, M.H.F. Tags: Articles Source Type: news
mtDNA point mutations are present at various levels of heteroplasmy in human oocytes
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Source: Molecular Human Reproduction - February 23, 2007 Authors: Jacobs, L., Gerards, M., Chinnery, P., Dumoulin, J., de Coo, I., Geraedts, J., Smeets, H. Tags: Articles Source Type: news
Asthenoteratozoospermia in mice lacking testis expressed gene 18 (Tex18)
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Source: Molecular Human Reproduction - February 23, 2007 Authors: Jaroszynski, L., Dev, A., Li, M., Meinhardt, A., de Rooij, D.G., Mueller, C., Bohm, D., Wolf, S., Adham, I.M., Wulf, G., Engel, W., Nayernia, K. Tags: Articles Source Type: news
Histone acetylation and subcellular localization of chromosomal protein BRD4 during mouse oocyte meiosis and mitosis
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Source: Molecular Human Reproduction - February 23, 2007 Authors: Nagashima, T., Maruyama, T., Furuya, M., Kajitani, T., Uchida, H., Masuda, H., Ono, M., Arase, T., Ozato, K., Yoshimura, Y. Tags: Articles Source Type: news
Mechanical stretch regulates TRPC expression and calcium entry in human myometrial smooth muscle cells
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Source: Molecular Human Reproduction - February 23, 2007 Authors: Dalrymple, A., Mahn, K., Poston, L., Songu-Mize, E., Tribe, R.M. Tags: Articles Source Type: news
Semi-automated imaging system to quantitate Her-2/neu membrane receptor immunoreactivity in human breast cancer
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Source: Cytometry Part A - February 23, 2007 Authors: Aparna S. Joshi, Girish M. Sharangpani, Kyle Porter, Sedigheh Keyhani, Carl Morrison, Amitabha S. Basu, Gauri A. Gholap, Abhi S. Gholap, Sanford H. Barsky Source Type: news
ICOS and B7 costimulatory molecule expression identifies activated cellular subsets in rheumatoid arthritis
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Source: Cytometry Part A - February 23, 2007 Authors: Jeffrey H. Ruth, James B. Rottman, Gillian A. Kingsbury, Anthony J. Coyle, G. Kenneth Haines III, Richard M. Pope, Alisa E. Koch Source Type: news
Origins of amino acid transporter loci in trypanosomatid parasites
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Source: BMC Evolutionary Biology - Latest articles - February 23, 2007 Authors: Andrew P Jackson Source Type: news
MyoD and Myogenin expression during myogenic phases in brown trout: A precocious onset of mosaic hyperplasia is a prerequisite for fast somatic growth
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Source: Developmental Dynamics - February 22, 2007 Authors: P. Steinbacher, J.R. Haslett, A. Obermayer, J. Marschallinger, H.C. Bauer, A.M. Sänger, W. Stoiber Source Type: news
Characterization of Ccw12p, a major key player in cell wall stability of Saccharomyces cerevisiae
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Source: Yeast - February 22, 2007 Authors: Enrico Ragni, Matthias Sipiczki, Sabine Strahl Source Type: news
Binding assay for incorporation of alkali-extractable proteins in the Saccharomyces cerevisiae cell wall
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Source: Yeast - February 22, 2007 Authors: Renata Tepari[cacute], Igor Stuparevi[cacute], Vladimir Mr[scaron]a Source Type: news
Activation of Microglia Acidifies Lysosomes and Leads to Degradation of Alzheimer Amyloid Fibrils.
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Source: Mol Biol Cell - February 21, 2007 Authors: Majumdar A, Cruz D, Asamoah N, Buxbaum A, Sohar I, Lobel P, Maxfield FR Tags: Mol Biol Cell Source Type: news
The Biogenesis of the Golgi Ribbon: The Roles of Membrane Input from the ER and of GM130.
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Source: Mol Biol Cell - February 21, 2007 Authors: Marra P, Salvatore L, Mironov A, Di Campli A, Di Tullio G, Trucco A, Beznoussenko G, Mironov A, De Matteis MA Tags: Mol Biol Cell Source Type: news
Revealing Early Steps of {alpha}2{beta}1 Integrin-mediated Adhesion to Collagen Type I Using Single-Cell Force Spectroscopy.
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Source: Mol Biol Cell - February 21, 2007 Authors: Taubenberger A, Cisneros DA, Friedrichs J, Puech PH, Muller DJ, Franz CM Tags: Mol Biol Cell Source Type: news
Caveolin 2 Regulates Endocytosis and Trafficking of the M1 Muscarinic Receptor in MDCK Epithelial Cells.
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Source: Mol Biol Cell - February 21, 2007 Authors: Shmuel M, Nodel-Berner E, Hyman T, Rouvinski A, Altschuler Y Tags: Mol Biol Cell Source Type: news
The RBCC Gene RFP2 (Leu5) Encodes a Novel Transmembrane E3 Ubiquitin Ligase Involved in ERAD.
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Source: Mol Biol Cell - February 21, 2007 Authors: Lerner M, Corcoran M, Cepeda D, Nielsen ML, Zubarev R, Pontén F, Uhlén M, Hober S, Grandér D, Sangfelt O Tags: Mol Biol Cell Source Type: news
The Short Arm of Laminin {gamma}2 Chain of Laminin-5 (Laminin-332) Binds Syndecan-1 and Regulates Cellular Adhesion and Migration by Suppressing Phosphorylation of Integrin {beta}4 Chain.
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Source: Mol Biol Cell - February 21, 2007 Authors: Ogawa T, Tsubota Y, Hashimoto J, Kariya Y, Miyazaki K Tags: Mol Biol Cell Source Type: news
Fatty Acid Remodeling of GPI-anchored Proteins Is Required for Their Raft Association.
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Source: Mol Biol Cell - February 21, 2007 Authors: Maeda Y, Tashima Y, Houjou T, Fujita M, Yoko-O T, Jigami Y, Taguchi R, Kinoshita T Tags: Mol Biol Cell Source Type: news
A Phenomics Approach in Yeast Links Proton and Calcium Pump Function in the Golgi.
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Source: Mol Biol Cell - February 21, 2007 Authors: Yadav J, Muend S, Zhang Y, Rao R Tags: Mol Biol Cell Source Type: news
ATF-2 Regulates Fat Metabolism in Drosophila.
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Source: Mol Biol Cell - February 21, 2007 Authors: Okamura T, Shimizu H, Nagao T, Ueda R, Ishii S Tags: Mol Biol Cell Source Type: news
DNA meets synthetic polymers-highly versatile hybrid materials
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Source: RSC - Organic Biomolecular Chemistry - February 21, 2007 Authors: Fikri E. AlemdarogluAndreas Herrmann Source Type: news
Clone-specific anti-CD45 blocking factor in patient plasma
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Source: Cytometry Part B: Clinical Cytometry - February 21, 2007 Authors: Samuel R. Wellhausen, Stephen P. Slone, James J. Miller Source Type: news
Enzyme-triggered cell attachment to hydrogel surfaces
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Source: RSC - Chemical Biology Virtual Journal latest articles - February 21, 2007 Authors: Simon J. ToddDavid Farrar Julie E. Gough Rein V. Ulijn Source Type: news
Distinct energetics and closing pathways for DNA polymerase beta with 8-oxoG template and different incoming nucleotides
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Source: BMC Structural Biology - Latest articles - February 21, 2007 Authors: Yanli Wang and Tamar Schlick Source Type: news
Phosphorylation of ERK in neurokinin 1 receptor-expressing neurons in laminae III and IV of the rat spinal dorsal horn following noxious stimulation
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Source: Molecular Pain - February 19, 2007 Authors: Erika Polgar, Annie D Campbell, Lynsey M MacIntyre, Masahiko Watanabe and Andrew J Todd Source Type: news
Dynamics of in silico leukocyte rolling, activation, and adhesion
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Source: BMC Systems Biology - Latest articles - February 19, 2007 Authors: Jonathan Tang, Klaus F. Ley and C. Anthony Hunt Source Type: news
Synthesis and evaluation of a new polymer-supported pseudoephedrine auxiliary for asymmetric alkylations on solid phase
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Source: RSC - Organic Biomolecular Chemistry - February 19, 2007 Authors: Andrea M. McGheeJean-Claude Kizirian David J. Procter Source Type: news
The gene encoding the splicing factor SF2/ASF is a proto-oncogene
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Source: Nature Structural and Molecular Biology - February 18, 2007 Authors: Rotem KarniElisa de StanchinaScott W LoweRahul SinhaDavid MuAdrian R Krainer Tags: Article Source Type: news
Yeast Jhd2p is a histone H3 Lys4 trimethyl demethylase
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Source: Nature Structural and Molecular Biology - February 18, 2007 Authors: Gaoyang LiangRobert J KloseKathryn E GardnerYi Zhang Tags: Brief Communication Source Type: news
Quantitative Evaluation of 2-Deoxy-2[F-18]fluoro-d
-glucose-Positron Emission Tomography Imaging on the Woodchuck Model of Hepatocellular Carcinoma with Histological Correlation
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Source: Molecular Imaging and Biology - February 17, 2007 Tags: Molecular Imaging and Biology Source Type: news
Optimizing Classification of Drug-Drug Interaction Potential for CYP450 Isoenzyme Inhibition Assays in Early Drug Discovery
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Source: Journal of Biomolecular Screening - February 16, 2007 Authors: Krippendorff, B.-F., Lienau, P., Reichel, A., Huisinga, W. Tags: Article Source Type: news
Heterogeneous Breast Tumoroids: An In Vitro Assay for Investigating Cellular Heterogeneity and Drug Delivery
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Source: Journal of Biomolecular Screening - February 16, 2007 Authors: Vamvakidou, A. P., Mondrinos, M. J., Petushi, S. P., Garcia, F. U., Lelkes, P. I., Tozeren, A. Tags: Article Source Type: news
Society Updates
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Source: Journal of Biomolecular Screening - February 16, 2007 Tags: Article Source Type: news
Novel 384-Well Population Patch Clamp Electrophysiology Assays for Ca2+-Activated K+ Channels
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Source: Journal of Biomolecular Screening - February 16, 2007 Authors: John, V. H., Dale, T. J., Hollands, E. C., Chen, M. X., Partington, L., Downie, D. L., Meadows, H. J., Trezise, D. J. Tags: Article Source Type: news
Product Focus: Assay Reagents, Supplies, and Kits
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Source: Journal of Biomolecular Screening - February 16, 2007 Tags: Article Source Type: news
Synthesis and Characterization of 5'-p-fluorosulfonylbenzoyl-2' (or 3')-(biotinyl)adenosine as an Activity-Based Probe for Protein Kinases
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Source: Journal of Biomolecular Screening - February 16, 2007 Authors: Ratcliffe, S. J., Yi, T., Khandekar, S. S. Tags: Article Source Type: news
A Novel Inhibitor of Mycobacterium tuberculosis Pantothenate Synthetase
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Source: Journal of Biomolecular Screening - February 16, 2007 Authors: White, E. L., Southworth, K., Ross, L., Cooley, S., Gill, R. B., Sosa, M. I., Manouvakhova, A., Rasmussen, L., Goulding, C., Eisenberg, D., Fletcher, T. M. Tags: Article Source Type: news
Quantitative Positron Emission Tomography Studies of the Serotonin Transporter in Humans Previously Treated with the Appetite Suppressants Fenfluramine or Dexfenfluramine