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This is a selection of articles from the February 2008 archive. Click here for this month's Molecular Biology headlines.

Combined treatment with l -carnitine and a pan-caspase inhibitor effectively reverses amiodarone-induced injury in cultured human lung epithelial cellsemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Apoptosis - February 29, 2008 Tags: Apoptosis Source Type: news

Alterations of proliferative and differentiation potentials of human embryonic stem cells during long-term culture.email this article save this article to My Clippings discuss this articlediscuss this article
Source: exp Mol Med - February 29, 2008 Authors: Park YB, Kim YY, Oh SK, Chung SG, Ku SY, Kim SH, Choi YM, Moon SY Tags: Exp Mol Med Source Type: news

Etoposide-induced Smad6 expression is required for the G1 to S phase transition of the cell cycle in CMT-93 mouse intestinal epithelial cells.email this article save this article to My Clippings discuss this articlediscuss this article
Source: exp Mol Med - February 29, 2008 Authors: Lee YS, Lee EK, Han IO, Park SH Tags: Exp Mol Med Source Type: news

Comprehensive analysis of the metabolome of Pseudomonas putida S12 grown on different carbon sourcesemail this article save this article to My Clippings discuss this articlediscuss this article
Source: RSC - Mol. BioSyst. latest articles - February 29, 2008 Authors: Mariet J. van der WerfKarin M. Overkamp Bas Muilwijk Maud M. Koek Bianca J. C. van der Werff-van der Vat Renger H. Jellema Leon Coulier Thomas Hankemeier Source Type: news

New chromogenic substrates for feruloyl esterasesemail this article save this article to My Clippings discuss this articlediscuss this article
Source: RSC - Organic Biomolecular Chemistry - February 29, 2008 Authors: Laurence MarmuseMichele Asther Emeline Fabre David Navarro Laurence Lesage-Meessen Marcel Asther Michael O'Donohue Sebastien Fort Hugues Driguez Source Type: news

The regulatory network of E. coli metabolism as a Boolean dynamical system exhibits both homeostasis and flexibility of responseemail this article save this article to My Clippings discuss this articlediscuss this article
Source: BMC Systems Biology - Latest articles - February 29, 2008 Authors: Areejit Samal and Sanjay Jain Source Type: news

Rutin inhibits osteoclast formation by decreasing reactive oxygen species and TNF-alpha by inhibiting activation of NF-kappaB.email this article save this article to My Clippings discuss this articlediscuss this article
Source: exp Mol Med - February 29, 2008 Authors: Kyung TW, Lee JE, Shin HH, Choi HS Tags: Exp Mol Med Source Type: news

Nur77 upregulates HIF-alpha by inhibiting pVHL-mediated degradation.email this article save this article to My Clippings discuss this articlediscuss this article
Source: exp Mol Med - February 29, 2008 Authors: Kim BY, Kim H, Cho EJ, Youn HD Tags: Exp Mol Med Source Type: news

There's more than one way to skin a cat: Yet another way to assess mitotic index by cytometryemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Cytometry Part A - February 28, 2008 Authors: Zbigniew Darzynkiewicz Source Type: news

Enzyme-catalysed synthesis and reactions of benzene oxide/oxepine derivatives of methyl benzoatesemail this article save this article to My Clippings discuss this articlediscuss this article
Source: RSC - Organic Biomolecular Chemistry - February 28, 2008 Authors: Derek R. BoydNarain D. Sharma John S. Harrison John. F. Malone W. Colin McRoberts John T. G. Hamilton David B. Harper Source Type: news

How many events is enough? Are you positive?email this article save this article to My Clippings discuss this articlediscuss this article
Source: Cytometry Part A - February 28, 2008 Authors: Mario Roederer Source Type: news

Crystal structure of human IPS-1/MAVS/VISA/Cardif caspase activation recruitment domainemail this article save this article to My Clippings discuss this articlediscuss this article
Source: BMC Structural Biology - Latest articles - February 28, 2008 Authors: Jane A Potter, Richard E Randall and Garry L Taylor Source Type: news

Approach to the hyacinthacines: first non-chiral pool synthesis of (+)-hyacinthacine A1email this article save this article to My Clippings discuss this articlediscuss this article
Source: RSC - Organic Biomolecular Chemistry - February 28, 2008 Authors: P. Venkatram ReddyAmael Veyron Peter Koos Alexandre Bayle Andrew E. Greene Philippe Delair Source Type: news

Enkephalin-encoding herpes simplex virus-1 decreases inflammation and hotplate sensitivity in a chronic pancreatitis modelemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Molecular Pain - February 28, 2008 Authors: Hong Yang, Terry A McNearney, Rong Chu, Ying Lu, Yong Ren, David C Yeomans, Steven P Wilson and Karin N Westlund Source Type: news

Synthesis of sialoclusters appended to calix[4]arene platforms via multiple azide-alkyne cycloaddition. New inhibitors of hemagglutination and cytopathic effect mediated by BK and influenza A virusesemail this article save this article to My Clippings discuss this articlediscuss this article
Source: RSC - Organic Biomolecular Chemistry - February 28, 2008 Authors: Alberto MarraLisa Moni Daniele Pazzi Alfredo Corallini Deborah Bridi Alessandro Dondoni Source Type: news

Cyclic tetrapeptides via the ring contraction strategy: chemical techniques useful for their identificationemail this article save this article to My Clippings discuss this articlediscuss this article
Source: RSC - Organic Biomolecular Chemistry - February 28, 2008 Authors: Douglas A. HortonGregory T. Bourne Justin Coughlan Sonya M. Kaiser Carolyn M. Jacobs Alun Jones Andreas Ruhmann Jill Y. Turner Mark L. Smythe Source Type: news

NeuroAIDS: Characteristics and Diagnosis of the Neurological Complications of AIDS.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Molecular Diagnosis & Therapy - February 27, 2008 Tags: Abstract HTML PDF (298 K) Source Type: news

Rapid Diagnostics for Methicillin-Resistant Staphylococcus aureus: Current Status.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Molecular Diagnosis & Therapy - February 27, 2008 Tags: Abstract HTML PDF (253 K) Source Type: news

TLR and MBL Gene Polymorphisms in Severe Acute Pancreatitis.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Molecular Diagnosis & Therapy - February 27, 2008 Tags: Abstract HTML PDF (239 K) Source Type: news

Regulation and Targeting of the Fission Yeast Formin cdc12p in Cytokinesis.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Mol Biol Cell - February 27, 2008 Authors: Yonetani A, Lustig RJ, Moseley JB, Takeda T, Goode BL, Chang F Tags: Mol Biol Cell Source Type: news

The Nup358-RanGAP Complex is Required for Efficient Importin {alpha}/{beta}-dependent Nuclear Import.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Mol Biol Cell - February 27, 2008 Authors: Hutten S, Flotho A, Melchior F, Kehlenbach RH Tags: Mol Biol Cell Source Type: news

Characterization of a temperature-sensitive mutation that impairs the function of yeast tRNA nucleotidyltransferaseemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Yeast - February 27, 2008 Authors: Xunying Shan, Tara A. Russell, Scott M. Paul, David B. Kushner, Paul B. M. Joyce Source Type: news

Multiplexed Dendritic Targeting of {alpha}CaMKII, NG and ARC RNAs by the A2 Pathway.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Mol Biol Cell - February 27, 2008 Authors: Gao Y, Tatavarty V, Korza G, Levin MK, Carson JH Tags: Mol Biol Cell Source Type: news

Block modification of rod-shaped [small pi] conjugated carbon frameworks with donor and acceptor groups toward highly fluorescent molecules: synthesis and emission characteristicsemail this article save this article to My Clippings discuss this articlediscuss this article
Source: RSC - Organic Biomolecular Chemistry - February 27, 2008 Authors: Takanori OchiYoshihiro Yamaguchi Tateaki Wakamiya Yoshio Matsubara Zen-ichi Yoshida Source Type: news

Caveolae Structure and Function.email this article save this article to My Clippings discuss this articlediscuss this article
Source: J Cell Mol Med - February 27, 2008 Authors: Thomas CM, Smart EJ Tags: J Cell Mol Med Source Type: news

Identification of multiple independent horizontal gene transfers into poxviruses using a comparative genomics approachemail this article save this article to My Clippings discuss this articlediscuss this article
Source: BMC Evolutionary Biology - Latest articles - February 27, 2008 Authors: Kirsten A Bratke and Aoife McLysaght Source Type: news

Performance of Integrated FDG-PET/CT for Differentiating Benign and Malignant Lung Lesions - Results from a Large Prospective Clinical Trialemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Molecular Imaging and Biology - February 26, 2008 Tags: Molecular Imaging and Biology Source Type: news

The evolution of genome size in antsemail this article save this article to My Clippings discuss this articlediscuss this article
Source: BMC Evolutionary Biology - Latest articles - February 26, 2008 Authors: Neil D Tsutsui, Andrew V Suarez, Joseph C Spagna and J SPENCER Johnston Source Type: news

IkappaB kinase beta (IKKbeta/IKK2/IKBKB)-A key molecule in signaling to the transcription factor NF-kappaB.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Cytokine and Growth Factor Reviews - February 26, 2008 Authors: Schmid JA, Birbach A Tags: Cytokine Growth Factor Rev Source Type: news

IGF2: Epigenetic regulation and role in development and disease.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Cytokine and Growth Factor Reviews - February 26, 2008 Authors: Chao W, D'Amore PA Tags: Cytokine Growth Factor Rev Source Type: news

Characterization of human mesenchymal stem cell secretome at early steps of adipocyte and osteoblast differentiationemail this article save this article to My Clippings discuss this articlediscuss this article
Source: BMC Molecular Biology - Latest articles - February 26, 2008 Authors: Chiara Chiellini, Olivia Cochet, Luc Negroni, Michel Samson, Marjorie Poggi, Gerard Ailhaud, Marie-Christine Alessi, Christian Dani and Ez-Zoubir Amri Source Type: news

Non-equilibrium estimates of gene flow inferred from nuclear genealogies suggest that Iberian and North African wall lizards (Podarcis spp.) are an assemblage of incipient speciesemail this article save this article to My Clippings discuss this articlediscuss this article
Source: BMC Evolutionary Biology - Latest articles - February 26, 2008 Authors: Catarina Pinho, D. James Harris and Nuno Ferrand Source Type: news

Muller's Ratchet and compensatory mutation in Caenorhabditis briggsae mitochondrial genome evolutionemail this article save this article to My Clippings discuss this articlediscuss this article
Source: BMC Evolutionary Biology - Latest articles - February 26, 2008 Authors: Dana K Howe and Dee R Denver Source Type: news

Daphnia Halloween genes encode cytochrome P450s mediating the synthesis of the arthropod molting hormones: evolutionary implicationsemail this article save this article to My Clippings discuss this articlediscuss this article
Source: BMC Evolutionary Biology - Latest articles - February 25, 2008 Authors: Kim F Rewitz and Lawrence I Gilbert Source Type: news

Liver-specific expression of p53-negative regulator mdm2 leads to growth retardation and fragile liver in zebrafishemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Developmental Dynamics - February 25, 2008 Authors: Li-Je Chen, Chia-Chun Hsu, Jiann-Ruey Hong, Luen-Kuang Jou, Hung-Chia Tseng, Jen-Leih Wu, Yih-Cherng Liou, Guor Mour Her Source Type: news

Direct solid-phase synthesis and fluorescence labeling of large, monodisperse mannosylated dendrons in a peptide synthesizeremail this article save this article to My Clippings discuss this articlediscuss this article
Source: RSC - Organic Biomolecular Chemistry - February 25, 2008 Authors: Eric Assen B. KantchevChung-Chieh Chang Shu-Fang Cheng Annie-Claude Roche Ding-Kwo Chang Source Type: news

LPS/TLR4 signal transduction pathway.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Cytokine - February 25, 2008 Authors: Lu YC, Yeh WC, Ohashi PS Tags: Cytokine Source Type: news

Effect of a long term treatment with a low dose granulocyte colony-stimulating factor on postinfarction process in the heart.email this article save this article to My Clippings discuss this articlediscuss this article
Source: J Cell Mol Med - February 24, 2008 Authors: Okada H, Takemura G, Li Y, Ohno T, Li L, Maruyama R, Esaki M, Miyata S, Kanamori H, Ogino A, Nakagawa M, Minatoguchi S, Fujiwar T, Fujiwara H Tags: J Cell Mol Med Source Type: news

Localisation of the low affinity nerve growth factor receptor p75 in human limbal epithelial cells.email this article save this article to My Clippings discuss this articlediscuss this article
Source: J Cell Mol Med - February 24, 2008 Authors: Di Girolamo N, Sarris M, Chiu J, Cheema H, Coroneo MT, Wakefield D Tags: J Cell Mol Med Source Type: news

Transcriptional activity and developmental expression of liver X receptor (lxr) in Zebrafishemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Developmental Dynamics - February 24, 2008 Authors: Amena Archer, Gilbert Lauter, Giselbert Hauptmann, Agneta Mode, Jan-Åke Gustafsson Source Type: news

Primary cilia: Integral to development and diseaseemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Developmental Dynamics - February 24, 2008 Authors: Peter Satir Source Type: news

Inactivation of zebrafish mrf4 leads to myofibril misalignment and motor axon growth disorganizationemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Developmental Dynamics - February 24, 2008 Authors: Yun-Hsin Wang, Chun-Kai Li, Gang-Hui Lee, Huey-Jen Tsay, Huai-Jen Tsai, Yau-Hung Chen Source Type: news

Caspases as therapeutic targets.email this article save this article to My Clippings discuss this articlediscuss this article
Source: J Cell Mol Med - February 24, 2008 Authors: Howley B, Fearnhead HO Tags: J Cell Mol Med Source Type: news

Alternative splicing and expression analysis of bovine DNA methyltransferase 1email this article save this article to My Clippings discuss this articlediscuss this article
Source: Developmental Dynamics - February 24, 2008 Authors: D. Fischer Russell, D. H. Betts Source Type: news

Diversity of interferon gamma and granulocyte-macrophage colony-stimulating factor in restoring immune dysfunction of dendritic cells and macrophages during polymicrobial sepsis.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Molecular Medicine - February 24, 2008 Authors: Flohé SB, Agrawal H, Flohé S, Rani M, Bangen JM, Schade FU Tags: Mol Med Source Type: news

Distinct structural elements of the adaptor ClpS are required for regulating degradation by ClpAPemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nature Structural and Molecular Biology - February 24, 2008 Authors: Jennifer Y HouRobert T SauerTania A Baker Tags: Article Source Type: news

Gene expression profiling demonstrates a novel role for fetal fibrocytes and the umbilical vessels in human fetoplacental development.email this article save this article to My Clippings discuss this articlediscuss this article
Source: J Cell Mol Med - February 24, 2008 Authors: Kim JS, Romero R, Tarca A, Lajeunesse C, Han YM, Kim MJ, Suh YL, Draghici S, Mittal P, Gotsch F, Kusanovic JP, Hassan S, Kim CJ Tags: J Cell Mol Med Source Type: news

Proteasome inhibitor-induced apoptosis is mediated by positive feed-back amplification of PKCdelta proteolytic activation and mitochondrial translocation.email this article save this article to My Clippings discuss this articlediscuss this article
Source: J Cell Mol Med - February 24, 2008 Authors: Sun F, Kanthasamy A, Song C, Yang Y, Anantharam V, Kanthasamy AG Tags: J Cell Mol Med Source Type: news

The development of several organs and appendages is impaired in mice lacking Sp6email this article save this article to My Clippings discuss this articlediscuss this article
Source: Developmental Dynamics - February 24, 2008 Authors: Valérie Hertveldt, Stéphane Louryan, Thierry van Reeth, Pierre Drèze, Pascale van Vooren, Josiane Szpirer, Claude Szpirer Source Type: news

Proliferation and differentiation of intestinal stem cells during metamorphosis of the red flour beetle, Tribolium castaneumemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Developmental Dynamics - February 24, 2008 Authors: R. Parthasarathy, Subba R. Palli Source Type: news

Hydrothermal Stability of Adenine Under Controlled Fugacities of N(2), CO (2) and H (2).email this article save this article to My Clippings discuss this articlediscuss this article
Source: Origins of Life and Evolution of the Biosphere - February 23, 2008 Authors: Franiatte M, Richard L, Elie M, Nguyen-Trung C, Perfetti E, Larowe DE Tags: Orig Life Evol Biosph Source Type: news

Raves and risks for erythropoietin.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Cytokine and Growth Factor Reviews - February 23, 2008 Authors: Maiese K, Chong ZZ, Shang YC Tags: Cytokine Growth Factor Rev Source Type: news

Post-Messinian evolutionary relationships across the Sicilian channel: Mitochondrial and nuclear markers link a new green toad from Sicily to African relativesemail this article save this article to My Clippings discuss this articlediscuss this article
Source: BMC Evolutionary Biology - Latest articles - February 23, 2008 Authors: Matthias Stock, Alessandra Sicilia, Natalia M Belfiore, David Buckley, Sabrina Lo Brutto, Mario Lo Valvo and Marco Arculeo Source Type: news

Inhibitory action of polyunsaturated fatty acids on Cdt1-geminin interaction.email this article save this article to My Clippings discuss this articlediscuss this article
Source: International Journal of Molecular Medicine - February 22, 2008 Authors: Mizushina Y, Takeuchi T, Takakusagi Y, Sugawara F, Sakaguchi K, Yoshida H, Fujita M Tags: Int J Mol Med Source Type: news

Fourier transform infrared spectromicroscopy and hierarchical cluster analysis of human meningiomas.email this article save this article to My Clippings discuss this articlediscuss this article
Source: International Journal of Molecular Medicine - February 22, 2008 Authors: Ali K, Lu Y, Christensen C, May T, Hyett C, Griebel R, Fourney D, Meguro K, Resch L, Sharma RK Tags: Int J Mol Med Source Type: news

Significance of mitochondrial calcium and nitric oxide for apoptosis of human breast cancer cells induced by tamoxifen and etoposide.email this article save this article to My Clippings discuss this articlediscuss this article
Source: International Journal of Molecular Medicine - February 22, 2008 Authors: Parihar A, Parihar MS, Ghafourifar P Tags: Int J Mol Med Source Type: news

Analysis of polymorphisms in the 3' untranslated region of the LDL receptor gene and their effect on plasma cholesterol levels and drug response.email this article save this article to My Clippings discuss this articlediscuss this article
Source: International Journal of Molecular Medicine - February 22, 2008 Authors: Chen W, Wang S, Ma Y, Zhou Y, Liu H, Strnad P, Kraemer FB, Krauss RM, Liu J Tags: Int J Mol Med Source Type: news

Tissue expression of porcine FoxO1 and its negative regulation during primary preadipocyte differentiation.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Molecular Biology Reports - February 22, 2008 Authors: Pang WJ, Yu TY, Bai L, Yang YJ, Yang GS Tags: Mol Biol Rep Source Type: news

An iodoetherification-dehydroiodination strategy for the synthesis of complex spiroketals from dihydroxyalkene precursorsemail this article save this article to My Clippings discuss this articlediscuss this article
Source: RSC - Organic Biomolecular Chemistry - February 22, 2008 Authors: K. A. TonyXiaohua Li Darrin Dabideen Jialiang Li David R. Mootoo Source Type: news

EAPF/Phafin-2, a novel endoplasmic reticulum-associated protein, facilitates TNF-α-triggered cellular apoptosis through endoplasmic reticulum-mitochondrial apoptotic pathwayemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Journal of Molecular Medicine - February 21, 2008 Tags: Journal of Molecular Medicine Source Type: news

Epigenetic regulation of Hox gene activation: the waltz of methylsemail this article save this article to My Clippings discuss this articlediscuss this article
Source: BioEssays - February 21, 2008 Authors: Natalia Soshnikova, Denis Duboule Tags: What the papers say Source Type: news

Intrinsic disorder in pathogenic and non-pathogenic microbes: discovering and analyzing the unfoldomes of early-branching eukaryotesemail this article save this article to My Clippings discuss this articlediscuss this article
Source: RSC - Mol. BioSyst. latest articles - February 21, 2008 Authors: Amrita MohanWilliam J. Sullivan Jr Predrag Radivojac A. Keith Dunker Vladimir N. Uversky Source Type: news

Modular transporters for subcellular cell-specific targeting of anti-tumor drugsemail this article save this article to My Clippings discuss this articlediscuss this article
Source: BioEssays - February 21, 2008 Authors: Alexander S. Sobolev Tags: Challenges Source Type: news

Self-assembled polyhydroxy fatty acids vesicles: a mechanism for plant cutin synthesisemail this article save this article to My Clippings discuss this articlediscuss this article
Source: BioEssays - February 21, 2008 Authors: José A. Heredia-Guerrero, José J. Benítez, Antonio Heredia Tags: Hypotheses Source Type: news

Epithelial topologyemail this article save this article to My Clippings discuss this articlediscuss this article
Source: BioEssays - February 21, 2008 Authors: Radhika Nagpal, Ankit Patel, Matthew C. Gibson Tags: Problems and paradigms Source Type: news

The epidermal growth factor receptor and its ligands in female reproduction: Insights from rodent models.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Cytokine and Growth Factor Reviews - February 21, 2008 Authors: Schneider MR, Wolf E Tags: Cytokine Growth Factor Rev Source Type: news

GRIM-19 Is Essential for Maintenance of Mitochondrial Membrane Potential.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Mol Biol Cell - February 20, 2008 Authors: Lu H, Cao X Tags: Mol Biol Cell Source Type: news

Proteasome modulators: essential chemical genetic tools for understanding human diseasesemail this article save this article to My Clippings discuss this articlediscuss this article
Source: RSC - Mol. BioSyst. latest articles - February 20, 2008 Authors: Marie WehenkelJin Tae Hong Kyung Bo Kim Source Type: news

Neuronal Death by Oxidative Stress Involves Activation of FOXO3 through a Two-Arm Pathway that Activates Stress Kinases and Attenuates Insulin-like Growth Factor I Signalling.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Mol Biol Cell - February 20, 2008 Authors: Dávila D, Torres-Aleman I Tags: Mol Biol Cell Source Type: news

The Cargo Receptors Surf4, ERGIC-53 and p25 are Required to Maintain the Architecture of ERGIC and Golgi.