This is a selection of articles from the March 2008 archive. Click here for this month's Molecular Biology headlines.
Cucurbit[7]uril host-guest complexes with small polar organic guests in aqueous solution
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Source: RSC - Organic Biomolecular Chemistry - March 31, 2008 Authors: Ian W. WymanDonal H. Macartney Source Type: news
Sitimagene ceradenovec, a gene therapeutic for the treatment of glioma
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Source: Current Opinion in Molecular Therapeutics - March 31, 2008 Authors: N Düzgünes Source Type: news
Cytocidal effect of interleukin 1 (IL-1) on HeLa cells is mediated by both soluble and transmembrane tumor necrosis factor (TNF).
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Source: Cytokine - March 31, 2008 Authors: Doszczak M, Pierzchalski A, Grzenkowicz J, Stasiłojć G, Bigda JJ Tags: Cytokine Source Type: news
Paper alert
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Source: Current Opinion in Molecular Therapeutics - March 31, 2008 Authors: RE Hurst Source Type: news
Synthesis of 3-(2-N,N-diethylaminoethoxy)indoles as potential 5-HT6 receptor ligands
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Source: RSC - Organic Biomolecular Chemistry - March 31, 2008 Authors: Karolin AlexNicolle Schwarz Vivek Khedkar Iliyas Ali Sayyed Annegret Tillack Dirk Michalik Jorg Holenz Jose Luis Diaz Matthias Beller Source Type: news
Multifunctional peptide-based nanosystems for improving delivery and molecular imaging
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Source: Current Opinion in Molecular Therapeutics - March 31, 2008 Authors: DF Emerich and CG Thanos Source Type: news
VB4-845: A conjugated recombinant antibody and immunotoxin for head and neck cancer and bladder cancer
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Source: Current Opinion in Molecular Therapeutics - March 31, 2008 Authors: K Biggers and N Scheinfeld Source Type: news
Membrane proteins as diagnostic biomarkers and targets for new therapies
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Source: Current Opinion in Molecular Therapeutics - March 31, 2008 Authors: D Josic, JG Clifton, S Kovac and DC Hixson Source Type: news
A scoring matrix approach to detecting miRNA target sites
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Source: Algorithms for Molecular Biology - March 31, 2008 Authors: Simon Moxon, Vincent Moulton and Jan T Kim Source Type: news
Human mastoid periosteum-derived stem cells: promising candidates for skeletal tissue engineering.
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Source: Journal of Tissue Engineering and Regenerative Medicine - March 31, 2008 Authors: Ringe J, Leinhase I, Stich S, Loch A, Neumann K, Haisch A, Häup T, Manz R, Kaps C, Sittinger M Tags: J Tissue Eng Regen Med Source Type: news
The therapeutic potential of antisense-mediated exon skipping
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Source: Current Opinion in Molecular Therapeutics - March 31, 2008 Authors: Ommen G-J van, Deutekom J van and A Aartsma-Rus Source Type: news
Populations of p53 codon 270 CGT to TGT mutant cells in SKH-1 mouse skin tumors induced by simulated solar light
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Source: Molecular Carcinogenesis - March 31, 2008 Authors: Tracie L. Verkler, Robert R. Delongchamp, Letha H. Couch, Barbara J. Miller, Alan Warbritton, Paul W. Mellick, Paul C. Howard, Barbara L. Parsons Source Type: news
Patent alert
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Source: Current Opinion in Molecular Therapeutics - March 31, 2008 Authors: Scientific Current Awareness Thomson Source Type: news
Synthesis of [small alpha]-cyclodextrin [2]-rotaxanes using chlorotriazine capping reagents
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Source: RSC - Organic Biomolecular Chemistry - March 31, 2008 Authors: Ryan E. DawsonSubashani Maniam Stephen F. Lincoln Christopher J. Easton Source Type: news
p16INK4a downregulation is involved in immortalization of primary human prostate epithelial cells induced by telomerase
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Source: Molecular Carcinogenesis - March 31, 2008 Authors: Genze Shao, Adayabalam S. Balajee, Tom K. Hei, Yongliang Zhao Source Type: news
Pleiotrophin inhibits transforming growth factor [beta]1-induced apoptosis in hepatoma cell lines
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Source: Molecular Carcinogenesis - March 31, 2008 Authors: Tae Jun Park, Bo Ra Jeong, Chise Tateno, Hong Seok Kim, Tomohiro Ogawa, In Kyoung Lim, Katsutoshi Yoshizato Source Type: news
Emerging role of microRNAs in disease pathogenesis and strategies for therapeutic modulation
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Source: Current Opinion in Molecular Therapeutics - March 31, 2008 Authors: J Mattes, A Collison and PS Foster Source Type: news
Resveratrol directly targets COX-2 to inhibit carcinogenesis
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Source: Molecular Carcinogenesis - March 31, 2008 Authors: Tatyana A. Zykova, Feng Zhu, Xiuhong Zhai, Wei-Ya Ma, Svetlana P. Ermakova, Ki Won Lee, Ann M. Bode, Zigang Dong Source Type: news
Sugar boost: When ribose modifications improve oligonucleotide performance
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Source: Current Opinion in Molecular Therapeutics - March 31, 2008 Authors: M Faria and H Ulrich Source Type: news
The regulatory activity of microRNA* species has substantial influence on microRNA and 3′ UTR evolution
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Source: Nature Structural and Molecular Biology - March 30, 2008 Authors: Katsutomo OkamuraMichael D PhillipsDavid M TylerHong DuanYu-ting ChouEric C Lai Tags: Article Source Type: news
MukB acts as a macromolecular clamp in DNA condensation
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Source: Nature Structural and Molecular Biology - March 30, 2008 Authors: Yuanbo CuiZoya M PetrushenkoValentin V Rybenkov Tags: Article Source Type: news
HSP70 is Associated with Endothelial Activation in Placental Vascular Diseases.
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Source: Molecular Medicine - March 30, 2008 Authors: Liu Y, Li N, You L, Liu X, Li H, Wang X Tags: Mol Med Source Type: news
Alteration of cystatin C levels in cerebrospinal fluid of patients with Guillain-Barré Syndrome by a proteomical approach.
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Source: Molecular Biology Reports - March 29, 2008 Authors: Yang Y, Liu S, Qin Z, Cui Y, Qin Y, Bai S Tags: Mol Biol Rep Source Type: news
C-terminal 37 residues of LRP promote the amyloidogenic processing of APP independent of FE65.
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Source: J Cell Mol Med - March 28, 2008 Authors: Lakshmana MK, Chen E, Yoon IS, Kang DE Tags: J Cell Mol Med Source Type: news
SILDENAFIL MEDIATED NEOVASCULARIZATION AND PROTECTION AGAINST MYOCARDIAL ISCHEMIA REPERFUSION INJURY IN RATS: PROBABLE ROLE OF VEGF/ ANGIOPOIETIN-1.
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Source: J Cell Mol Med - March 28, 2008 Authors: Koneru S, Penumathsa SV, Thirunavukkarasu M, Vidavalur R, Zhan L, Singal PK, Engelman RM, Das DK, Maulik N Tags: J Cell Mol Med Source Type: news
H(2)S-induced pancreatic acinar cell apoptosis is mediated via JNK and p38 MAP Kinase.
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Source: J Cell Mol Med - March 28, 2008 Authors: Adhikari S, Bhatia M Tags: J Cell Mol Med Source Type: news
Enzymatic resolution and evaluation of enantiomers of cis-5[prime or minute]-hydroxythalidomide
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Source: RSC - Organic Biomolecular Chemistry - March 28, 2008 Authors: Takeshi YamamotoNorio Shibata Masayuki Takashima Shuichi Nakamura Takeshi Toru Nozomu Matsunaga Hideaki Hara Source Type: news
Rapid generation of macrocycles with natural-product-like side chains by multiple multicomponent macrocyclizations (MiBs)
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Source: RSC - Organic Biomolecular Chemistry - March 28, 2008 Authors: Daniel G. RiveraOtilie E. Vercillo Ludger A. Wessjohann Source Type: news
Electronic volume of CD34 positive cells from peripheral blood apheresis samples
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Source: Cytometry Part B: Clinical Cytometry - March 28, 2008 Authors: Sherry Shariatmadar, Siddharth Sharma, Raquel Cabana, Scott Powell, Phillip Ruiz, Awtar Krishan Source Type: news
Treatment of Diabetic Rats with Encapsulated Islets.
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Source: J Cell Mol Med - March 28, 2008 Authors: Sweet IR, Yanay O, Waldron L, Gilbert M, Fuller JM, Tupling T, Lernmark A, Osborne WR Tags: J Cell Mol Med Source Type: news
Discovery of a new series of jatrophane and lathyrane diterpenes as potent and specific P-glycoprotein modulators
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Source: RSC - Organic Biomolecular Chemistry - March 28, 2008 Authors: Elisa BarileMarianna Borriello Attilio Di Pietro Agnes Doreau Caterina Fattorusso Ernesto Fattorusso Virginia Lanzotti Source Type: news
New insights on signaling cascades induced by cross-talk between angiotensin II and aldosterone
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Source: Journal of Molecular Medicine - March 27, 2008 Tags: Journal of Molecular Medicine Source Type: news
Transcription factor FBI-1 acts as a dual regulator in adipogenesis by coordinated regulation of cyclin-A and E2F-4
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Source: Journal of Molecular Medicine - March 27, 2008 Tags: Journal of Molecular Medicine Source Type: news
Nine color flow cytometry for accurate measurement of T cell subsets and cytokine responses. Part I: Panel design by an empiric approach
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Source: Cytometry Part A - March 27, 2008 Authors: Bridget E. McLaughlin, Nicole Baumgarth, Martin Bigos, Mario Roederer, Stephen C. De Rosa, John D. Altman, Douglas F. Nixon, Janet Ottinger, Carol Oxford, Thomas G. Evans, David M. Asmuth Source Type: news
Protein aggregation in the brain - the molecular basis for Alzheimer's and Parkinson's Diseases.
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Source: Molecular Medicine - March 27, 2008 Authors: Irvine GB, El-Agnaf OM, Shankar GM, Walsh DM Tags: Mol Med Source Type: news
The phylogeny of the Mammalian Heme Peroxidases and the evolution of their diverse functions
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Source: BMC Evolutionary Biology - Latest articles - March 27, 2008 Authors: Noeleen B Loughran, Brendan O'Connor, Ciaran O'Fagain and Mary J O'Connell Source Type: news
Signal transduction pathways used by NLR-type innate immune receptors
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Source: RSC - Mol. BioSyst. latest articles - March 27, 2008 Authors: Thomas A. Kufer Source Type: news
Both selective and neutral processes drive GC content evolution in the human genome
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Source: BMC Evolutionary Biology - Latest articles - March 27, 2008 Authors: Uberto Pozzoli, Giorgia Menozzi, Matteo Fumagalli, Matteo Cereda, Giacomo P Comi, Rachele Cagliani, Nereo Bresolin and Manuela Sironi Source Type: news
Pyrrolo-dC oligonucleotides bearing alkynyl side chains with terminal triple bonds: synthesis, base pairing and fluorescent dye conjugates prepared by the azide-alkyne "click" reaction
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Source: RSC - Organic Biomolecular Chemistry - March 26, 2008 Authors: Frank SeelaVenkata Ramana Sirivolu Source Type: news
Bone regeneration induced by adenoviral vectors carrying til-1/Cbfa1 genes implanted with biodegradable porous materials in animal models of osteonecrosis of the femoral head.
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Source: Journal of Tissue Engineering and Regenerative Medicine - March 26, 2008 Authors: Sakai S, Tamura M, Mishima H, Kojima H, Uemura T Tags: J Tissue Eng Regen Med Source Type: news
Cyclen-based bismacrocycles for biological anion recognition. A potentiometric and NMR study of AMP, ADP and ATP nucleotide complexation
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Source: RSC - Organic Biomolecular Chemistry - March 26, 2008 Authors: Anne-Sophie DelepineRaphael Tripier Henri Handel Source Type: news
Pyk2 Regulates Spreading and Migration of Eosinophils after {beta}2 Integrin Adhesion.
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Source: American Journal of Respiratory Cell and Molecular Biology - March 26, 2008 Authors: Zhu X, Boetticher E, Wang L, Duan Y, Learoyd J, Leff AR Tags: Am J Respir Cell Mol Biol Source Type: news
Directed Expression of Transgenes to Alveolar Type I Cells in the Mouse.
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Source: American Journal of Respiratory Cell and Molecular Biology - March 26, 2008 Authors: Vanderbilt JN, Allen L, Gonzalez RF, Tigue Z, Edmondson J, Ansaldi D, Gillespie AM, Dobbs LG Tags: Am J Respir Cell Mol Biol Source Type: news
Spliceosomal snRNPs Repeatedly Cycle through Cajal Bodies.
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Source: Mol Biol Cell - March 26, 2008 Authors: Stanek D, Pridalova J, Novotny I, Huranová M, Blazikova M, Wen X, Sapra AK, Neugebauer KM Tags: Mol Biol Cell Source Type: news
Ear1p and Ssh4p Are New Adaptors of the Ubiquitin Ligase Rsp5p for Cargo Ubiquitylation and Sorting at Multivesicular Bodies.
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Source: Mol Biol Cell - March 26, 2008 Authors: Léon S, Erpapazoglou Z, Haguenauer-Tsapis R Tags: Mol Biol Cell Source Type: news
Requirement of the Human GARP Complex for Mannose 6-phosphate-receptor-dependent Sorting of Cathepsin D to Lysosomes.
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Source: Mol Biol Cell - March 26, 2008 Authors: Pérez-Victoria FJ, Mardones GA, Bonifacino JS Tags: Mol Biol Cell Source Type: news
Clarification of the role of N-glycans on the common beta-subunit of the human IL-3, IL-5 and GM-CSF receptors and the murine IL-3 beta-receptor in ligand-binding and receptor activation.
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Source: Cytokine - March 26, 2008 Authors: Murphy JM, Soboleva TA, Mirza S, Ford SC, Olsen JE, Chen J, Young IG Tags: Cytokine Source Type: news
The ubiquitous environmental pollutant perfluorooctanoicacid inhibits feeding behavior via peroxisome proliferator-activated receptor-alpha.
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Source: International Journal of Molecular Medicine - March 25, 2008 Authors: Asakawa A, Toyoshima M, Harada KH, Fujimiya M, Inoue K, Koizumi A Tags: Int J Mol Med Source Type: news
The efficacy of apolipoprotein E deficiency in cerebral aneurysm formation.
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Source: International Journal of Molecular Medicine - March 25, 2008 Authors: Aoki T, Moriwaki T, Takagi Y, Kataoka H, Yang J, Nozaki K, Hashimoto N Tags: Int J Mol Med Source Type: news
Synthesis and antitumor activity of aromatic camptothecin esters.
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Source: International Journal of Molecular Medicine - March 25, 2008 Authors: Cao Z, Mendoza J, Dejesus A, Vardeman D, Giovanella B Tags: Int J Mol Med Source Type: news
SREBP-1c, regulated by the insulin and AMPK signaling pathways, plays a role in nonalcoholic fatty liver disease.
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Source: International Journal of Molecular Medicine - March 25, 2008 Authors: Kohjima M, Higuchi N, Kato M, Kotoh K, Yoshimoto T, Fujino T, Yada M, Yada R, Harada N, Enjoji M, Takayanagi R, Nakamuta M Tags: Int J Mol Med Source Type: news
Short-term exposure to high-pressure ventilation leads to pulmonary biotrauma and systemic inflammation in the rat.
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Source: International Journal of Molecular Medicine - March 25, 2008 Authors: Hoegl S, Boost KA, Flondor M, Scheiermann P, Muhl H, Pfeilschifter J, Zwissler B, Hofstetter C Tags: Int J Mol Med Source Type: news
Suppression of NF-kappaB activation blocks osteoclastic bone resorption during estrogen deficiency.
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Source: International Journal of Molecular Medicine - March 25, 2008 Authors: Strait K, Li Y, Dillehay DL, Weitzmann MN Tags: Int J Mol Med Source Type: news
Expression of avian prickle genes during early development and organogenesis
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Source: Developmental Dynamics - March 25, 2008 Authors: Oliver Cooper, Dylan Sweetman, Laura Wagstaff, Andrea Münsterberg Source Type: news
Comparative analysis of genetic toxicity of AZT and ddI antiretrovirals in somatic cells of Drosophila melanogaster
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Source: Environmental and Molecular Mutagenesis - March 25, 2008 Authors: Nilza Nascimento Guimarães, Karla de Castro Pereira, Heloísa Helena Rodrigues de Andrade, Maurício Lehmann, Kênya Silva Cunha Source Type: news
Evaluation of the genotoxicity of river sediments from industrialized and unaffected areas using a battery of short-term bioassays
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Source: Environmental and Molecular Mutagenesis - March 25, 2008 Authors: Assia Aouadene, Carole Di Giorgio, Luc Sarrazin, Xavier Moreau, Laetitia De Jong, Fabrice Garcia, Alain Thiery, Alain Botta, Michel De Méo Source Type: news
Nuclear ferritin-mediated protection of corneal epithelial cells from oxidative damage to DNA
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Source: Developmental Dynamics - March 25, 2008 Authors: Cindy Cai, Anna Ching, Christopher Lagace, Thomas Linsenmayer Source Type: news
Charge environments around phosphorylation sites in proteins
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Source: BMC Structural Biology - Latest articles - March 25, 2008 Authors: James Kitchen, Rebecca E Saunders and Jim Warwicker Source Type: news
The Ino80 chromatin-remodeling enzyme regulates replisome function and stability
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Source: Nature Structural and Molecular Biology - March 23, 2008 Authors: Manolis Papamichos-ChronakisCraig L Peterson Tags: Article Source Type: news
An unannotated alpha/beta hydrolase superfamily member, ABHD6 differentially expressed among cancer cell lines.
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Source: Molecular Biology Reports - March 22, 2008 Authors: Li F, Fei X, Xu J, Ji C Tags: Mol Biol Rep Source Type: news
PhyloFinder: an intelligent search engine for phylogenetic tree databases
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Source: BMC Evolutionary Biology - Latest articles - March 21, 2008 Authors: Duhong Chen, J. Gordon Burleigh, Mukul S. Bansal and David Fernandez-Baca Source Type: news
Identification of a novel human lactate dehydrogenase gene LDHAL6A, which activates transcriptional activities of AP1(PMA).
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Source: Molecular Biology Reports - March 20, 2008 Authors: Chen X, Gu X, Shan Y, Tang W, Yuan J, Zhong Z, Wang Y, Huang W, Wan B, Yu L Tags: Mol Biol Rep Source Type: news
Inhibition of PI3K/AKT and MEK/ERK pathways act synergistically to enhance antiangiogenic effects of EGCG through activation of FOXO transcription factor
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Source: Journal of Molecular Signaling - March 20, 2008 Authors: Sharmila Shankar, Qinghe Chen and Rakesh K. Srivastava Source Type: news
Comments in a Discussion: Differential Rates of D: - and L: -tyrosine Crystallization.
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Source: Origins of Life and Evolution of the Biosphere - March 20, 2008 Authors: Shinitzky M, Deamer D Tags: Orig Life Evol Biosph Source Type: news
Temporal PTEN Inactivation Causes Proliferation of Saphenous Vein Smooth Muscle Cells of Human CABG Conduits.
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Source: J Cell Mol Med - March 19, 2008 Authors: Mitra AK, Jia G, Gangahar DM, Agrawal DK Tags: J Cell Mol Med Source Type: news
The importance of surfaces in single-molecule bioscience
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Source: RSC - Mol. BioSyst. latest articles - March 19, 2008 Authors: Mari-Liis VisnapuuDaniel Duzdevich Eric C. Greene Source Type: news
Product Focus: Software, Databases, and Information Services
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Source: Journal of Biomolecular Screening - March 19, 2008 Tags: Article Source Type: news
Systematic and Simultaneous Gene Profiling of 84 Drug-Metabolizing Genes in Primary Human Hepatocytes
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Source: Journal of Biomolecular Screening - March 19, 2008 Authors: Ning, B., Dial, S., Sun, Y., Wang, J., Yang, J., Guo, L. Tags: Article Source Type: news
The Novel Tail-anchored Membrane Protein Mff Controls Mitochondrial and Peroxisomal Fission in Mammalian Cells.
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