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This is a selection of articles from the February 2008 archive. Click here for this month's Research headlines.

Selected Update: Stem cells: Safeguarding pluripotencyemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nature Signaling Update - February 29, 2008 Source Type: info

Selected Update: Gene regulation: Gathering a bouquet of miRNA targetsemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nature Signaling Update - February 29, 2008 Source Type: info

Research Library: Smad3 and NFAT cooperate to induce Foxp3 expression through its enhanceremail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nature Signaling Update - February 29, 2008 Source Type: info

Extramural Associates Research Development Award (EARDA) (G11)email this article save this article to My Clippings discuss this articlediscuss this article
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 29, 2008 Source Type: info

Mayo Clinic researchers propose new strategies to combat side effects of common breast cancer drug treatmentemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Mayo Clinic Research News - February 28, 2008 Authors: Mayo Clinic Source Type: info

Networking an organismemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nature Methods - February 28, 2008 Authors: Natalie de Souza Tags: Research Highlights Source Type: info

An origami chip of DNAemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nature Methods - February 28, 2008 Authors: Irene Kaganman Tags: Research Highlights Source Type: info

A global view of transcriptional regulation by nuclear receptors: gene expression, factor localization, and DNA sequence analysis.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Nucl Recept Signal - February 28, 2008 Authors: Kininis M, Kraus WL Tags: Nucl Recept Signal Source Type: info

Estrogen receptor beta: an overview and update.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Nucl Recept Signal - February 28, 2008 Authors: Zhao C, Dahlman-Wright K, Gustafsson JA Tags: Nucl Recept Signal Source Type: info

Structural basis for recognition of Co2+ by RNA aptamersemail this article save this article to My Clippings discuss this articlediscuss this article
Source: FEBS Journal - February 28, 2008 Tags: article Source Type: info

Notice Regarding PAR-06-485 Occupational Safety and Health Education and Research Centersemail this article save this article to My Clippings discuss this articlediscuss this article
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 28, 2008 Source Type: info

Limited Competition for Data Deposition and Analyses of Genome Wide Association Studies of Mental Disorders (Collaborative R01)email this article save this article to My Clippings discuss this articlediscuss this article
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 28, 2008 Source Type: info

Notice of Change in Council Review Dates for RFA-DK-07-004, RFA-DK-07-006, RFA-DK-07-010 and RFA-DK-07-012email this article save this article to My Clippings discuss this articlediscuss this article
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 28, 2008 Source Type: info

The third RNA recognition motif of Drosophila ELAV protein has a role in multimerizationemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nucleic Acids Research - February 28, 2008 Authors: Toba, G., White, K. Tags: RNA Source Type: info

Assembly and structural analysis of a covalently closed nano-scale DNA cageemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nucleic Acids Research - February 28, 2008 Authors: Andersen, F. F., Knudsen, B., Oliveira, C. L. P., Frohlich, R. F., Kruger, D., Bungert, J., Agbandje-McKenna, M., McKenna, R., Juul, S., Veigaard, C., Koch, J., Rubinstein, J. L., Guldbrandtsen, B., Hede, M. S., Karlsson, G., Andersen, A. H., Pedersen, J. Tags: Structural Biology Source Type: info

Saccharomyces cerevisiae HMO1 interacts with TFIID and participates in start site selection by RNA polymerase IIemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nucleic Acids Research - February 28, 2008 Authors: Kasahara, K., Ki, S., Aoyama, K., Takahashi, H., Kokubo, T. Tags: Molecular Biology Source Type: info

Detection of a circadian enhancer in the mDbp promoter using prokaryotic transposon vector-based strategyemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nucleic Acids Research - February 28, 2008 Authors: Kiyohara, Y. B., Nishii, K., Ukai-Tadenuma, M., Ueda, H. R., Uchiyama, Y., Yagita, K. Tags: Genomics Methods Online Source Type: info

Structural insights into RNA-dependent eukaryal and archaeal selenocysteine formationemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nucleic Acids Research - February 28, 2008 Authors: Araiso, Y., Palioura, S., Ishitani, R., Sherrer, R. L., O'Donoghue, P., Yuan, J., Oshikane, H., Domae, N., DeFranco, J., Soll, D., Nureki, O. Tags: Structural Biology Source Type: info

Loop dependence of the stability and dynamics of nucleic acid hairpinsemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nucleic Acids Research - February 28, 2008 Authors: Kuznetsov, S. V., Ren, C.-C., Woodson, S. A., Ansari, A. Tags: Structural Biology Source Type: info

Drosophila Ebi mediates Snail-dependent transcriptional repression through HDAC3-induced histone deacetylationemail this article save this article to My Clippings discuss this articlediscuss this article
Source: The EMBO Journal AOP - February 28, 2008 Authors: Dai QiMattias BergmanHitoshi AiharaYutaka NibuMattias Mannervik Tags: Article Source Type: info

The cucumovirus 2b gene drives selection of inter-viral recombinants affecting the crossover site, the acceptor RNA and the rate of selectionemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nucleic Acids Research - February 28, 2008 Authors: Shi, B.-J., Symons, R. H., Palukaitis, P. Tags: RNA Source Type: info

Proteomic screen defines the hepatocyte nuclear factor 1{alpha}-binding partners and identifies HMGB1 as a new cofactor of HNF1{alpha}email this article save this article to My Clippings discuss this articlediscuss this article
Source: Nucleic Acids Research - February 28, 2008 Authors: Yu, M., Wang, J., Li, W., Yuan, Y. Z., Li, C. Y., Qian, X. H., Xu, W. X., Zhan, Y. Q., Yang, X. M. Tags: Molecular Biology Source Type: info

Conserved elements with potential to form polymorphic G-quadruplex structures in the first intron of human genesemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nucleic Acids Research - February 28, 2008 Authors: Eddy, J., Maizels, N. Tags: Genomics Source Type: info

Induction of initial heart α-actin, smooth muscle α-actin, in chick pregastrula epiblast: The role of hypoblast and fibroblast growth factor-8email this article save this article to My Clippings discuss this articlediscuss this article
Source: Development, Growth and Differentiation - February 27, 2008 Tags: article Source Type: info

Do animal personalities emerge?email this article save this article to My Clippings discuss this articlediscuss this article
Source: Nature - February 27, 2008 Authors: François MassolPierre-André Crochet Tags: Brief Communication Arising Source Type: info

Topoisomerase inhibitors as anti-arthritic agentsemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Inflammation Research - February 27, 2008 Tags: Inflammation Research Source Type: info

Development and Aging Expression of Cystathionine-Beta Synthase in the Temporal Lobe and Cerebellum of Down Syndrome Patientsemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Neuroembryology and Aging - February 27, 2008 Source Type: info

Postnatal Developmental Changes of Vitreous and Lens Volumes in Sprague-Dawley Ratsemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Neuroembryology and Aging - February 27, 2008 Source Type: info

Warwick & Coventry Primary Care Researchemail this article save this article to My Clippings discuss this articlediscuss this article
Source: RDFunding RSS feed - February 27, 2008 Source Type: info

CO2 regulator SLAC1 and its homologues are essential for anion homeostasis in plant cellsemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nature AOP - February 27, 2008 Authors: Juntaro NegiOsamu MatsudaTakashi NagasawaYasuhiro ObaHideyuki TakahashiMaki Kawai-YamadaHirofumi UchimiyaMimi HashimotoKoh Iba Tags: Letter Source Type: info

Political debate: it is a risk, but one that's worth takingemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nature - February 27, 2008 Authors: Neal Lane Tags: Correspondence Source Type: info

Abstractionsemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nature - February 27, 2008 Tags: Authors Source Type: info

In utero Repair of Myelomeningocele: Rationale, Initial Clinical Experience and a Randomized Controlled Prospective Clinical Trialemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Neuroembryology and Aging - February 25, 2008 Source Type: info

BWH Researchers Identify Mutated Genes Unique to Mesothelioma Tumorsemail this article save this article to My Clippings discuss this articlediscuss this article
Source: BWH for Journalists - February 24, 2008 Source Type: info

SNP discovery and allele frequency estimation by deep sequencing of reduced representation librariesemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nature Methods - February 24, 2008 Authors: Curtis P Van TassellTimothy P L SmithLakshmi K MatukumalliJeremy F TaylorRobert D SchnabelCynthia Taylor LawleyChristian D HaudenschildStephen S MooreWesley C WarrenTad S Sonstegard Tags: Article Source Type: info

Identification of a serotonin/glutamate receptor complex implicated in psychosisemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nature AOP - February 24, 2008 Authors: Javier González-MaesoRosalind L. AngTony YuenPokman ChanNoelia V. WeisstaubJuan F. López-GiménezMingming ZhouYuuya OkawaLuis F. CalladoGraeme MilliganJay A. GingrichMarta FilizolaJ. Javier MeanaStuart C. Sealfon Tags: Letter Source Type: info

Preserving cell shape under environmental stressemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nature AOP - February 24, 2008 Authors: Boaz CookRobert W. HardyWilliam B. McConnaugheyCharles S. Zuker Tags: Letter Source Type: info

Selected Update: Tumour immunology: TGFbeta betrays immunity for tumorigenesisemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nature Signaling Update - February 22, 2008 Source Type: info

Centers of Excellence in Genomics Science (CEGS) (P50)email this article save this article to My Clippings discuss this articlediscuss this article
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 22, 2008 Source Type: info

Notice of Clarification of Funding Ceiling for RFA-OH-08-003email this article save this article to My Clippings discuss this articlediscuss this article
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 22, 2008 Source Type: info

The Use of an Anti-CD40 Agonist Monoclonal Antibody During Immunizations Enhances Hybridoma Generationemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Hybridoma - February 22, 2008 Tags: article Source Type: info

Production and Characterization of Monoclonal Antibody to Botulinum Neurotoxin Type B Light Chain by Phage Displayemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Hybridoma - February 22, 2008 Tags: article Source Type: info

Monoclonal Antibody-Based Lateral Flow Assay for Detection of Botulinum Neurotoxin Type Aemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Hybridoma - February 22, 2008 Tags: article Source Type: info

Value and feasibility of HPV DNA test in cervical scraping smearsemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Journal of Huazhong University of Science and Technology -- Medical Sciences -- - February 22, 2008 Tags: Journal of Huazhong University of Science and Technology -- Medical Sciences -- Source Type: info

Functional role of dendritic cells in patients with unstable anginaemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Journal of Huazhong University of Science and Technology -- Medical Sciences -- - February 22, 2008 Tags: Journal of Huazhong University of Science and Technology -- Medical Sciences -- Source Type: info

Effects of postoperative enteral immune-enhancing diet on plasma endotoxin level, plasma endotoxin inactivation capacity and clinical outcomeemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Journal of Huazhong University of Science and Technology -- Medical Sciences -- - February 22, 2008 Tags: Journal of Huazhong University of Science and Technology -- Medical Sciences -- Source Type: info

Toward a global database for the molecular typing of Saccharomyces cerevisiae strainsemail this article save this article to My Clippings discuss this articlediscuss this article
Source: FEMS Yeast Research - February 22, 2008 Tags: article Source Type: info

LPS Induces Hypoxia-Inducible Factor 1 Activation in Macrophage-Differentiated Cells in a Reactive Oxygen Species–Dependent Manneremail this article save this article to My Clippings discuss this articlediscuss this article
Source: Antioxidants and Redox Signaling - February 21, 2008 Tags: article Source Type: info

Cooperative Research Partnerships for Biodefense and Emerging Infectious Diseases (U01)email this article save this article to My Clippings discuss this articlediscuss this article
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 21, 2008 Source Type: info

Molecular Phenotypes for Lung Diseases (R01)email this article save this article to My Clippings discuss this articlediscuss this article
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 21, 2008 Source Type: info

Administrative Supplements for Making Knockout Miceemail this article save this article to My Clippings discuss this articlediscuss this article
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 21, 2008 Source Type: info

Notice of Amendment to the Foreign Component Restriction, Institutional Clinical and Translational Science Award (U54), RFA-RM-06-002, RM-07-002 and RM-07-007email this article save this article to My Clippings discuss this articlediscuss this article
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 21, 2008 Source Type: info

Participation of NINDS in PA-08-071, Lab to Marketplace: Tools for Brain and Behavioral Research (SBIR [R43/R44])email this article save this article to My Clippings discuss this articlediscuss this article
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 21, 2008 Source Type: info

Nominations open for the BA Award Lectures 2008email this article save this article to My Clippings discuss this articlediscuss this article
Source: Medical Research Council Funding News - February 21, 2008 Source Type: info

A methodological framework to distinguish spectrum effects from spectrum biases and to assess diagnostic and screening test accuracy for patient populations. Application to the Papanicolaou cervical cancer smear testemail this article save this article to My Clippings discuss this articlediscuss this article
Source: BMC Medical Research Methodology - Latest articles - February 21, 2008 Authors: Caroline Elie and Joel Coste Source Type: info

Mutant Huntingtin reduces HSP70 expression through the sequestration of NF-Y transcription factoremail this article save this article to My Clippings discuss this articlediscuss this article
Source: The EMBO Journal AOP - February 21, 2008 Authors: Tomoyuki YamanakaHaruko MiyazakiFumitaka OyamaMasaru KurosawaChika WashizuHiroshi DoiNobuyuki Nukina Tags: Article Source Type: info

Perturbed desmosomal cadherin expression in grainy head-like 1-null miceemail this article save this article to My Clippings discuss this articlediscuss this article
Source: The EMBO Journal AOP - February 21, 2008 Authors: Tomasz WilanowskiJacinta CaddyStephen B TingNikki R HislopLoretta CerrutiAlana AudenLin-Lin ZhaoStephen AsquithSarah EllisRodney SinclairJohn M CunninghamStephen M Jane Tags: Article Source Type: info

Protective effects of a new metalloporphyrin on paraquat-induced oxidative stress and apoptosis in N27 cellsemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Acta Biochimica et Biophysica Sinica - February 20, 2008 Tags: article Source Type: info

Energetic neutral atoms as the explanation for the high-velocity hydrogen around HD 209458bemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nature - February 20, 2008 Authors: M. HolmströmA. EkenbäckF. SelsisT. PenzH. LammerP. Wurz Tags: Letter Source Type: info

Phosphoinositide signalling links O-GlcNAc transferase to insulin resistanceemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nature - February 20, 2008 Authors: Xiaoyong YangPat P. OngusahaPhilip D. MilesJoyce C. HavstadFengxue ZhangW. Venus SoJeffrey E. KudlowRobert H. MichellJerrold M. OlefskySeth J. FieldRonald M. Evans Tags: Article Source Type: info

Global trends in emerging infectious diseasesemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nature - February 20, 2008 Authors: Kate E. JonesNikkita G. PatelMarc A. LevyAdam StoreygardDeborah BalkJohn L. GittlemanPeter Daszak Tags: Letter Source Type: info

HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1αemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nature - February 20, 2008 Authors: Zoltan AranyShi-Yin FooYanhong MaJorge L. RuasArchana Bommi-ReddyGeoffrey GirnunMarcus CooperDina LaznikJessica ChinsomboonShamina M. RangwalaKwan Hyuck BaekAnthony RosenzweigBruce M. Spiegelman Tags: Letter Source Type: info

Martian stepped-delta formation by rapid water releaseemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nature - February 20, 2008 Authors: Erin R. KraalMaurits van DijkGeorge PostmaMaarten G. Kleinhans Tags: Letter Source Type: info

Role of melatonin in regulating matrix metalloproteinase-9 via tissue inhibitors of metalloproteinase-1 during protection against endometriosisemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Journal of Pineal Research - February 20, 2008 Tags: article Source Type: info

Networking Technique Enables Gene Discoveryemail this article save this article to My Clippings discuss this articlediscuss this article
Source: NIGMS Biomedical Beat - February 20, 2008 Source Type: info

Exhibition: Cultures in the capitalemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nature - February 20, 2008 Authors: Jane Rees Tags: Books and Arts Source Type: info

The developmental genetics of congenital heart diseaseemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nature - February 20, 2008 Authors: Benoit G. Bruneau Tags: Insight Source Type: info

Interrelationship between serum and sputum inflammatory mediators in chronic obstructive pulmonary disease.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Braz J Med Biol Res - February 20, 2008 Authors: Bizeto L, Mazzolini AB, Ribeiro M, Stelmach R, Cukier A, Nunes MP Tags: Braz J Med Biol Res Source Type: info

The search for new cardiovascular biomarkersemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nature - February 20, 2008 Authors: Robert E. GersztenThomas J. Wang Tags: Insight Source Type: info

Architectural healingemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nature - February 20, 2008 Authors: D. Kirk Hamilton Tags: Books and Arts Source Type: info

Imaging of atherosclerotic cardiovascular diseaseemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nature - February 20, 2008 Authors: Javier SanzZahi A. Fayad Tags: Insight Source Type: info

Proline-catalysed Mannich reactions of acetaldehydeemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nature AOP - February 20, 2008 Authors: Jung Woon YangCarley ChandlerMichael StadlerDaniela KampenBenjamin List Tags: Letter Source Type: info

Citations in supplementary information are invisibleemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Nature - February 20, 2008 Authors: Frank Seeber Tags: Correspondence Source Type: info

A peptide deformylase–ribosome complex reveals mechanism of nascent chain pro