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What to do if you want to be a cruise ship doctor
In 2013 I began searching for ways I could change my career to reduce my workload, but not give up medicine altogether. During that time I took a cruise and looked at various jobs I could do on a cruise ship. One of the jobs I was qualified for, I thought, was to be a Cruise Ship Doctor. After talking with the ship’s doctor to find out what it was like to be the doctor on a ship, I realized that I would enjoy that life. When I arrived back home I sent in an application to a cruise line. I was promptly informed that general surgeons were not qualified to be a ship’s doctor. They only accept physicians who practice emerg...
Source: Kevin, M.D. - Medical Weblog - May 25, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/cory-fawcett" rel="tag" > Cory Fawcett, MD < /a > Tags: Physician Practice Management Primary Care Source Type: blogs

Uncovering the Senolytic Mechanism of Piperlongumine
Senolytic compounds are those capable of selectively destroying senescent cells. They are useful because the buildup of senescent cells over time is one of the root causes of aging. A number of mechanisms have been discovered by which senescent cells can be provoked into self-destruction, such as bcl-2 inhibition or interference in FOXO4-p53 interactions. These examples are fairly well understood. Other mechanisms are known but less well understood; they require more work in order to proceed on the production of improved senolytic compounds. In some cases, however, the primary mechanism of action of a compound found...
Source: Fight Aging! - May 21, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

What do low-tar cigarettes, low-fat yogurt and healthy whole grains have in common?
Followers of the Undoctored and Wheat Belly books and lifestyle understand a basic truth in logic: Just because something is less bad does not necessarily make it good. Low-tar cigarettes have less of the toxic compounds that leave the brown residue–“tar”–after tobacco is burned, but smoking low-tar cigarettes does not reduce risk for lung cancer, mouth/throat cancer, or cardiovascular disease. From Stanford.edu  on the impact of tobacco advertising: Claims of low ‘tar,’ less ‘tar,’ or even lowest ‘tar’ have been circulating in cigarette advertisements for dec...
Source: Wheat Belly Blog - May 16, 2018 Category: Cardiology Authors: Dr. Davis Tags: Grain Free Lifestyle News & Updates blood sugar diabetes diy health Dr. Davis grain-free grains healthy whole-grains low-carb low-fat undoctored wheat wheat belly Wheat Belly Total Health Source Type: blogs

Fight Aging! Newsletter, May 7th 2018
The objective here is a set of tests that (a) match up to the expected outcome based on human trials of mitochondrially targeted antioxidants, and (b) that anyone can run without the need to involve a physician, as that always adds significant time and expense. These tests are focused on the cardiovascular system, particularly measures influenced by vascular stiffness, and some consideration given to parameters relevant to oxidative stress and the development of atherosclerosis. A standard blood test, with inflammatory markers. An oxidized LDL cholesterol assessment. Resting heart rate and blood pressure. Heart r...
Source: Fight Aging! - May 6, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

No Microbiome Santa Claus we cannot magically convert correlative studies into causal ones. And scientists dishing out medical advice about vaping based on such bad science is ridiculous.
Conclusions. In summary, we found that tobacco smokingsignificantly alters the bacterial profiles in feces, buccal, and saliva samples.Nooooooooooooooooo. Nooooooo. No.So - you might ask -- why does this matter? This is just a little bit of a word choice issue right? Wrong. The press release and the paper mislead as to what was found here. You might then say "so what - what does it matter?". Well, it does matter because when you make these types of misleading statements they might get picked up by the press or the public. Like in the examples below:Daily Mail:An incentive to switch to e-cigare...
Source: The Tree of Life - April 30, 2018 Category: Microbiology Authors: Jonathan Eisen Source Type: blogs

4 ways to protect against skin cancer (other than sunscreen)
It’s almost May and here in the northeast, front-of-the-pharmacy aisles are filled with myriad brands and types of sunscreen. While sunscreen is essential to lowering your risk for skin cancer, there are other simple, over-the-counter options you can incorporate into your summer skin protection routine. Nicotinamide may help prevent certain skin cancers Nicotinamide is a form of vitamin B3 that has been shown to reduce the number of skin cancers. In a randomized controlled trial performed in Australia (published in the New England Journal of Medicine), the risks of basal cell carcinoma and squamous cell carcinoma were si...
Source: Harvard Health Blog - April 27, 2018 Category: Consumer Health News Authors: Emily S. Ruiz, MD, MPH Tags: Cancer Health Prevention Skin and Hair Care Source Type: blogs

Fight Aging! Newsletter, April 16th 2018
This study demonstrates that small peptide domains derived from native protein amelogenin can be utilized to construct a mineral layer on damaged human enamel in vitro. Six groups were prepared to carry out remineralization on artificially created lesions on enamel: (1) no treatment, (2) Ca2+ and PO43- only, (3) 1100 ppm fluoride (F), (4) 20 000 ppm F, (5) 1100 ppm F and peptide, and (6) peptide alone. While the 1100 ppm F sample (indicative of common F content of toothpaste for homecare) did not deliver F to the thinly deposited mineral layer, high F test sample (indicative of clinical varnish treatment) formed mainly C...
Source: Fight Aging! - April 15, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Anti-Microbial Nanotechnology: Interview with Adrian Fellows, Head of R & D at AGA Nanotech
AGA Nanotech, a medtech company based in the UK, has developed nanotechnologies aimed at overcoming antimicrobial resistance, with a view to offering an alternative to conventional antibiotics. The company has collaborated with researchers from Unive...
Source: Medgadget - April 12, 2018 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Materials Nanomedicine Public Health Source Type: blogs

Fight Aging! Newsletter, April 2nd 2018
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - April 1, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

How silence can help us learn from our patients
As the patient talked, I found myself nodding my head. In so many ways, she was just like me. Highly educated, a professional, a woman who had worked hard and long to get where she was. And then cancer took it all away, or at least that’s the way she described it. She was diagnosed with metastatic cancer one year ago and finally had time to take a breath after the rigors of surgery, radiation, endocrine manipulation therapy, and chemotherapy. Nothing seems to have gone right for her; she was hospitalized with febrile neutropenia twice during the months of chemotherapy, she has osteoporosis and has had to stop the winter ...
Source: Kevin, M.D. - Medical Weblog - March 29, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/anne-katz" rel="tag" > Anne Katz, RN, PhD < /a > Tags: Conditions Oncology/Hematology Source Type: blogs

What Causes the Chronic Inflammation of Aging?
Many mechanisms of aging are two-way streets: A accelerates B, but B also makes A worse. Or A leads to B that causes C which aggravates A. Chronic inflammation, a persistent and damaging activation of the immune system, is a player in many of these sorts of circular relationships and feedback loops. The open access paper noted here briefly covers some of the known contributions to increased inflammation in aging. Inflammation is a vital part of the way in which the immune system coordinates with tissues in order to repel invaders and respond to injury; it is beneficial when temporary. When inflammation is constant, however...
Source: Fight Aging! - March 26, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

The Other Opioid Crisis: Hospital Shortages Lead To Patient Pain, Medical Error
I came across this public-accesss story, and wanted to share the perspective: Pauline Bartolone, Kaiser Health News Even as opioids flood American communities and fuel widespread addiction, hospitals are facing a dangerous shortage of the powerful painkillers needed by patients in acute pain, according to doctors, pharmacists and a coalition of health groups. The shortage, though more significant in some places than others, has left many hospitals and surgical centers scrambling to find enough injectable morphine, Dilaudid and fentanyl — drugs given to patients undergoing surgery, fighting cancer or suffering traumatic i...
Source: Suboxone Talk Zone - March 26, 2018 Category: Addiction Authors: admin Tags: Acute Pain Anesthesia Public policy surgery Chronic pain opioid addiction Source Type: blogs