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Total 782 results found since Jan 2013.

The Implications of Greater Amounts of Remnant Cholesterol in the Bloodstream
We examined 9293 individuals from the Copenhagen General Population Study using nuclear magnetic resonance spectroscopy measurements of total cholesterol, free- and esterified cholesterol, triglycerides, phospholipids, and particle concentration. Fourteen subclasses of decreasing size and their lipid constituents were analysed: six subclasses were very low-density lipoprotein (VLDL), one intermediate-density lipoprotein (IDL), three low-density lipoprotein (LDL), and four subclasses were high-density lipoprotein (HDL). Remnant lipoproteins were VLDL and IDL combined. Mean nonfasting cholesterol concentration was 72â...
Source: Fight Aging! - August 7, 2019 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

OMI Confirmed by POCUS Echo in a 50 year man
Case submitted and written by Alex BraceyA man in his 50s with no significant past medical history presented from a local beach with epigastric " burning " pain that had been intermittent for 4 days until this morning when it became constant at rest. He had associated nausea and diaphoresis, but overall looked well and had arrived by private vehicle to front triage. An ECG was performed there and brought to me for review:What do you think?STE in V2-4 that might just barely meet STEMI criteriaSTE in aVL, and to a lesser extent lead IObvious reciprocal STD in II, III, aVFRegardless of whether this ECG truly meets STEMI crite...
Source: Dr. Smith's ECG Blog - August 1, 2019 Category: Cardiology Authors: Pendell Source Type: blogs

A Text Message in the Middle of the night. Do you give thrombolytics?
I awoke in the morning and discovered a text with this ECG that was sent 6 hours prior by a former resident:" 60 year old with classic chest pain.  The cath lab is occupied for the next 90 minutes.  Cards says " not a STEMI " .  Thinking of giving lytics. "What do you think?What do you do?I texted back: " Sorry for delay!  Was sleeping.  This is OMI!!  Did you give lytics?  Proximal LAD.  Great catch! "There is 0.5 mm of ST Elevation in V3-V6.  The T-wave in V4 is far too large for the QRS.  The LAD occlusion formula would be very high due to the extremely small R-wave in V...
Source: Dr. Smith's ECG Blog - July 16, 2019 Category: Cardiology Authors: Steve Smith Source Type: blogs

Landmark Results Achieved in Aging and Chronic Disease: Danish Group Extends Disease-free Life by 8 Years
By WILLIAM H. BESTERMANN JR., MD New Scientific Breakthroughs Can Provide a Longer Healthier Life Twenty-one years of follow-up comparing usual care with a protocol-driven team-based intervention in diabetes proved that healthy life in humans can be prolonged by 8 years. These results were achieved at a lower per patient per year cost. Aging researchers have been confident that we will soon be able to prolong healthy life. This landmark study shows this ambitious goal can be achieved now with lifestyle intervention and a few highly effective proven medications. These medications interfere with the core molecular biol...
Source: The Health Care Blog - July 11, 2019 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Patients aging chronic disease Denmark Diabetes William Bestermann Source Type: blogs

Artificial Bacterial Protein Allows Stem Cells to Home to the Heart
Researchers at the University of Bristol have developed a way to make stem cells move toward heart tissue when they are injected intravenously. The treatment could improve the efficacy of stem cell therapies for heart disease, which are currently ham...
Source: Medgadget - July 8, 2019 Category: Medical Devices Authors: Conn Hastings Tags: Cardiac Surgery Cardiology Genetics Rehab Source Type: blogs

Would you have given thrombolytics to this NSTEMI patient?
Case submitted by Dr. James AlvaA middle aged male called EMS for chest pain. EMS arrived and confirmed that the patient was complaining of chest pain and shortness of breath.They recorded this prehospital ECG:What do you think?Normal QRS complex rhythm with hyperacute T-waves in V2-V6, I and aVL. Slight STE in V2 only, with significant STD and thus de-Winter pattern in V4-V6. Leads II and III show reciprocal depression of the ST segment (II) and T-wave (III). This is diagnostic of acute myocardial infarction of the anterolateral walls, with the most likely etiology being Occlusion of the LAD. In other words, this ECG show...
Source: Dr. Smith's ECG Blog - July 6, 2019 Category: Cardiology Authors: Pendell Source Type: blogs

BraveHeart Wireless Announces FDA Clearance of the BraveHeart Life Sensor Cardiac Monitoring System
• The BraveHeart Life Sensor Cardiac Monitoring system has been cleared for use in health care settings. • The Life Sensor monitoring system securely captures patients’ heart rate and EKG data, and transmits the data to health care providers...
Source: Medgadget - July 1, 2019 Category: Medical Devices Authors: Laurie Dove Tags: Cardiology Sponsored Content Source Type: blogs

Fight Aging! Newsletter, July 1st 2019
In this study, we determine whether transient reintroduction of embryonic stem cell cycle miR-294 promotes cardiomyocyte cell cycle reentry enhancing cardiac repair after myocardial injury. A doxycycline-inducible AAV9-miR-294 vector was delivered to mice for activating miR-294 in myocytes for 14 days continuously after myocardial infarction. miR-294-treated mice significantly improved left ventricular functions together with decreased infarct size and apoptosis 8 weeks after MI. Myocyte cell cycle reentry increased in miR-294 hearts parallel to increased small myocyte number in the heart. Isolated adult myocytes from miR-...
Source: Fight Aging! - June 30, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

2 ECGs texted to me. Minimal STE in inferior leads. How important is it?
These 2 ECGs were texted to me with the words " I think acute MI, but cardiology does not. "I believed these to be 2 serial ECGs:ECG 1: (later found to be time zero):Computer read: " minimal ST depression 0.025 mm "There is a small amount of STE in II, III, aVFFrom less than 0.5 mm - 0.5 mm.There is les than 0.5 mm of reciprocal ST depression in aVL, and an inverted T-waveAnd the other: (later found to be time 24 minutes):Now there is more STE and more STDOne very telling finding are the ST segments in V2-V6:ST depression has developed in V2-V6, downsloping in V4-V6.Though minimal, this is very specific adjunctive data for...
Source: Dr. Smith's ECG Blog - June 22, 2019 Category: Cardiology Authors: Steve Smith Source Type: blogs

AI System Can Identify Cardiac Arrest by Listening to Breathing
Researchers at the University of Washington have used machine learning to teach an AI system to identify when someone is having a cardiac arrest. The system learned to identify agonal breathing, which occurs when someone gasps for breath during cardi...
Source: Medgadget - June 20, 2019 Category: Medical Devices Authors: Conn Hastings Tags: Cardiology Emergency Medicine Informatics Net News cardiac arrest heart attacks Source Type: blogs

Patches Made of Heart Tissue Going to Clinical Trials
Stem cell therapies to heal damaged hearts have proven to be lacking so far, probably because simply injecting new cells into afflicted regions isn’t enough. Researchers from Imperial College London have now created patches made of cardiac tiss...
Source: Medgadget - June 4, 2019 Category: Medical Devices Authors: Medgadget Editors Tags: Cardiac Surgery Cardiology Materials Radiology Rehab Vascular Surgery Source Type: blogs

A man in his sixties with chest pain at midnight with undetectable troponin
Written by Pendell MeyersA male in his 60s with no known past medical history presented at midnight with chest pain over the past 3 hours. The pain started just after eating, and at first he thought it was " reflux, " however he decided to call 911 after a few hours when it did not improve.Here is his presenting ECG:What do you think?Here are the relevant findings:Slight STE in V12.5 mm STE in V2Slight STD in V4-V6Definite STD in II, III, and aVFHyperacute T-waves in V2, and likely also in aVLThese findings are highly specific for LAD occlusion. We have many cases of this pattern on this blog, involving STE and hyperacute ...
Source: Dr. Smith's ECG Blog - May 25, 2019 Category: Cardiology Authors: Pendell Source Type: blogs

Drug eluting stent vs drug coated balloon in primary PCI
Paclitaxel coated balloon angioplasty was compared with drug eluting stent in acute ST elevation myocardial Infarction (STEMI) in the REVELATION ( REVascularization with paclitaxEL-coated balloon angioplasty versus drug-eluting stenting in acute myocardial infarcTION) Trial [1]. Drug coated balloons for angioplasty aims at reducing the potential disadvantages of stent implantation like stent thrombosis. It is thought improve the restenosis compared to plain old balloon angioplasty. REVELATION was a single center prospective randomized trial in patients with STEMI. Those with a new culprit lesion in a native coronary arte...
Source: Cardiophile MD - May 25, 2019 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology Source Type: blogs

Ultrathin strut drug eluting stents for small vessel disease
Implantation of stents in small vessels is often avoided due to the risk of adverse events like stent thrombosis and restenosis. Ultra thin strut drug eluting stents may an option in such cases. A study published in JAMA Cardiology compared ultra thin strut stents with very thin strut stents and previous generation drug eluting stents in small vessel coronary artery disease [1]. It was a pre-specified substudy of the Comparison of Biodegradable Polymer and Durable Polymer Drug-eluting Stents in an All Comers Population (BIO-RESORT) trial. The types of stents used were ultrathin strut sirolimus eluting stents, very thin...
Source: Cardiophile MD - May 24, 2019 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Angiography and Interventions Coronary Interventions Source Type: blogs

Diabetes: What price comfort and habit?
I was in suburban Chicago recently one morning, hoping to get something to eat for breakfast. I’d heard that the Panera chain was now serving breakfast that you could order any way you wanted. It’s called “Panera Bread,” but I thought I’d give it a try, as I’ve safely consumed their salads in past. At the counter, I placed my order for 3 eggs over easy, sausage, and bacon—not perfect, given our inability to scrutinize foods and ingredients in such places, but I was willing to try. Obviously, I turned down the breads/toasts that were included. The middle-aged Hispanic woman behind t...
Source: Wheat Belly Blog - May 15, 2019 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly diabetes grain-free grains Inflammation sugar undoctored Source Type: blogs