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Fight Aging! Newsletter, June 29th 2020
In conclusion, metabolomics is a promising approach for the assessment of biological age and appears complementary to established epigenetic clocks. Sedentary Behavior Raises the Risk of Cancer Mortality https://www.fightaging.org/archives/2020/06/sedentary-behavior-raises-the-risk-of-cancer-mortality/ Living a sedentary lifestyle is known to be harmful to long term health, raising the risk of age-related disease and mortality. Researchers here show that a sedentary life specifically increases cancer mortality, and does so independently of other factors. This is one of many, many reasons to maintain a re...
Source: Fight Aging! - June 28, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

How risky is a hug right now?
“Can I get a hug?” It’s a simple question for a simple act that’s been especially missed because of COVID-19 distancing. “Human beings need social contact,” says Dr. Eugene Beresin, executive director of The Clay Center for Young Healthy Minds at Massachusetts General Hospital, and professor of psychiatry at Harvard Medical School. “We are not hermits. We are not solo pilots. We are pack animals.” Not that it needs more promotion, but along with feeling connected, a hug has been shown to help fight off a cold and help your mood when dealing with conflict. But even as restrictions have started to loosen, the...
Source: Harvard Health Blog - June 25, 2020 Category: Consumer Health News Authors: Steve Calechman Tags: Cold and Flu Coronavirus and COVID-19 Health Risks and Prevention Safety Source Type: blogs

Lifestyle Medicine Could Be The Key For Digital Health Adoption
I’ve been wearing my Fitbit for a couple of years and only remove it when I shower. I use it to track my sleep and its smart alarm wakes me up at the optimal time every morning. With the pocketable Kardia, I regularly check my ECG at home to detect any anomalies. For an in-depth analysis of what my genetic makeup predisposes me to, I had my whole genome sequenced. And I bring relevant data to my general practitioner during my checkups so that we can decide on preventive measures. In short, I’m trying to live like the patient of the future. However, posing as such a patient is not feasible for many among us. Firs...
Source: The Medical Futurist - June 23, 2020 Category: Information Technology Authors: Prans Tags: Lifestyle medicine E-Patients Health Sensors & Trackers Healthcare Design Medical Education Personalized Medicine sleep stress food scanner sleep apnea Apple Watch Dr. Vernes Baylor ACLM Source Type: blogs

Fight Aging! Newsletter, June 22nd 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - June 21, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Threonine Restriction Promotes Health in Mice
Calorie restriction, eating up to 40% fewer calories while maintaining optimal micronutrient intake, improves health and reliably extends life in most species. In humans it produces robust improvements in health, but we experience a much lesser degree of life extension than short-lived species such as mice. Calorie restriction research has given rise to a number of lines of work in which specific dietary components (such as individual essential amino acids) are restricted, to try to identify which of these components are responsible for the benefits. A sizable fraction of the calorie restriction response is thought to be t...
Source: Fight Aging! - June 16, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Cancer Recovery During a Pandemic
It’s been 18 months since I finished chemo for breast cancer, 15 months since I finished radiation at this writing, June 2020. My hair grew back a year ago. The tingling in my fingers is gone. I used to have heart flutters and some chest congestion; those symptoms have passed.   I had a mammogram recently; it was good. No “signs of malignancy.” That’s how the official language goes. I wasn’t expecting anything bad, but you never know. I saw my oncologist the following week. She felt my scar tissue. I have tenderness under my armpit where four lymph nodes were removed. She said it all felt fine. She also told m...
Source: World of Psychology - June 14, 2020 Category: Psychiatry & Psychology Authors: Felicia Carparelli Tags: Health-related Mental Health and Wellness Personal Cancer coronavirus COVID-19 pandemic social distancing Source Type: blogs

Fight Aging! Newsletter, June 8th 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - June 7, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Podcast: Lazy, Crazy, and Disgusting – How Stigma is Everywhere
What is stigma? And how does it affect a person’s mental health and quality of life? In today’s Psych Central Podcast, Gabe talks with anthropologists Alex Brewis and Amber Wutich about the deeply dehumanizing impact of stigma in society. Whether it’s your mental health diagnosis, your neighborhood, your race or your inability to meet society’s standards in some way, stigma is alive and well in today’s world. People even tend to stigmatize themselves, intensifying their suffering.  Why are people so quick to stigmatize? And how does stigma affect mental health treatment? Tune into the show for an in-depth look ...
Source: World of Psychology - June 4, 2020 Category: Psychiatry & Psychology Authors: The Psych Central Podcast Tags: General Interview Mental Health and Wellness Podcast Psychology The Psych Central Show Source Type: blogs

Targeting the Failure of Mitophagy as a Basis for Treating Age-Related Disease
Evidence strongly suggests that the global faltering of mitochondrial function throughout the body with advancing age has a lot to do with a decline in the effectiveness of mitophagy. Mitochondria are the power plants of the cell, a herd of hundreds swarming and replicating like bacteria in every cell to produce the chemical energy store molecule ATP. Mitophagy is the specialized form of autophagy that destroys worn and damaged mitochondria, recycling their component parts. Without it, cells would become overtaken by broken, malfunctioning mitochondria. Mitochondrial dysfunction leads to too little ATP, but also higher lev...
Source: Fight Aging! - June 3, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, June 1st 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - May 31, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Visceral Fat Behaves Differently in Long-Lived Dwarf Mice
A few varieties of dwarf mice exhibit considerable longevity. They are produced via forms of mutation that disable portions of growth hormone metabolism, such as via growth hormone receptor knockout. Most research has thus focused on insulin signaling, IGF-1, and other pathways closely tied to growth hormone. Here, scientists instead focus on the behavior of fat tissue in these long-lived mouse lineages, suggesting that the significant differences they observe in the metabolism of visceral fat may contribute to the impact on aging. It is well known that visceral fat is metabolically active, and excess amounts create...
Source: Fight Aging! - May 29, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Vaccination as a Limited Option for Removal of Senescent Cells
In today's open access paper, the authors demonstrate a form of vaccination against a surface marker that appears on a subset of senescent T cells that reside in fat tissue, thus directing the rest of the immune system to attack and destroy these cells. There is good evidence for excess fat tissue to result in an increased burden of senescent cells, which disrupt metabolism via the generation of inflammatory signals. A novel branch of medicine is under construction, based on senolytic therapies capable of selectively destroying senescent cells in aged tissues. The growing numbers of senescent cells in older people (and eve...
Source: Fight Aging! - May 26, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Chemicals and Pregnant Women: Taking Care of Your Unborn Baby
This study is not a warning of a scary new epidemic of problems arriving with next year’s babies. Instead, it’s a peak behind the curtain at what might be the hidden story behind the marvelous kids we already see on today’s playgrounds across the country. Most are very healthy – among the healthiest kids in history. Yes, too many are overweight. Too many have asthma. Too many have allergies. Too many have learning problems. Too many start puberty early. More than half have some chronic illness. But this isn’t slowing kids down as much as the devastating infectious diseases of the past. It is a vib...
Source: Conversations with Dr Greene - May 25, 2020 Category: Child Development Authors: Alan Greene MD Tags: Uncategorized Source Type: blogs

Fight Aging! Newsletter, May 25th 2020
In conclusion, our results suggest a previously unknown mechanism whereby the canonical NF-κB cascade and a mitochondrial fission pathway interdependently regulate endothelial inflammation. Lin28 as a Target for Nerve Regeneration https://www.fightaging.org/archives/2020/05/lin28-as-a-target-for-nerve-regeneration/ Researchers here show that the gene Lin28 regulates axon regrowth. In mice, raised levels of Lin28 produce greater regeneration of nerve injuries. Past research has investigated Lin28 from the standpoint of producing a more general improvement in regenerative capacity. It improves mitochondri...
Source: Fight Aging! - May 24, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Podcast: Using Nature and Animals to Manage Anxiety
 When was the last time you simply enjoyed being in nature? Whether it’s a camping trip to the mountains, a walk in the park or just watching the squirrels from your backyard, being in nature is profoundly healing. In today’s Psych Central Podcast, our guest Richard Louv, a journalist, author and co-founder of the nonprofit Children & Nature Network, discusses the science behind nature’s healing powers. What counts as “nature?” Are pets included? What are some modern barriers to accessing nature, and how can we overcome them? Join us for the answers to these questions and more. SUBSCRIBE & REVIEW Gu...
Source: World of Psychology - May 21, 2020 Category: Psychiatry & Psychology Authors: The Psych Central Podcast Tags: Anxiety and Panic General Green and Environment Interview LifeHelper Mental Health and Wellness Podcast Stress The Psych Central Show Source Type: blogs