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Commentary on More Drastic Scenarios of Partial Brain and Full Body Replacement
Is outright replacement of tissues a viable option for the treatment of aging? There are factions within the longevity-interested community who think that the paths to either (a) engineering replacement brain tissue for parts of the brain not involved in memory, or (b) transplantation of an old head onto a young body or brain into a young body, are short enough to be worth pursuing, where "short enough" means a few decades of work given sufficient funding. To my mind, major surgery of the sort implied by replacement of large sections of tissue or entire organs is something to be avoided in later life, given the risks and c...
Source: Fight Aging! - January 10, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Bonus Features – January 8, 2023 – Omnibus bill extends telehealth expansion through end of 2024, 60% of solution providers pouring all event marketing money into in-person events, and more
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. News On Dec. 29, 2022, President Biden signed the omnibus spending bill. The biggest news for healthcare IT was the extension of telehealth expansion under Medicare through the end of 2024. This includes expansion of originating...
Source: EMR and HIPAA - January 8, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT 4medica ADAPT AdvancedMD AHA Ardent Health Services Blendid Brian Berning Cadence Carenet Health Carol DeVol CharmHealth CipherHealth Comcast Healthcare CORL directtrust East Tennessee Health Information Netwo Source Type: blogs

Healthcare AI – 2023 Health IT Predictions
As we head into 2023, we wanted to kick off the new year with a series of 2023 Health IT predictions.  We asked the Healthcare IT Today community to submit their predictions and we received a wide ranging set of responses that we grouped into a number of themes.  Check out our communities predictions below and be sure to add your own thoughts and/or places you disagree with these predictions in the comments and on social media. Check out our community’s healthcare AI predictions. Evangelos Hytopoulos, Sr. Director of Data Science at iRhythm Technologies There is no doubt that AI has become mainstream in many areas....
Source: EMR and HIPAA - January 3, 2023 Category: Information Technology Authors: John Lynn Tags: AI/Machine Learning Health IT Company Healthcare IT 2023 Health IT Predictions 4D Path Carlene MacMillan CommBox Dave Bennett Evangelos Hytopoulos Gabriel Mecklenburg Healthcare AI Hinge Health iRhythm Technologies Judy Jiao Na Source Type: blogs

Fight Aging! Newsletter, January 2nd 2023
In conclusion, circulating monocytes in older adults exhibit increased expression of activation, adhesion, and migration markers, but decreased expression of co-inhibitory molecules. MERTK Inhibition Increases Bone Density via Increased Osteoblast Activity https://www.fightaging.org/archives/2022/12/mertk-inhibition-increases-bone-density-via-increased-osteoblast-activity/ Bone density results from the balance of constant activity on the part of osteoblasts and osteoclasts, the former building bone, the latter breaking it down. With advancing age, the balance of activity shifts to favor osteoclasts, prod...
Source: Fight Aging! - January 1, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

A Look Back at 2022: Progress Towards the Treatment of Aging as a Medical Condition
At the end of 2022, we can reflect on the fact that we are steadily entering a new era of medicine, one in which mechanisms of aging are targeted rather than ignored. It is a profound change, one that will change the shape of a human life and ultimately the human condition by eliminating the greatest sources of suffering and death in the world. Year after year, we see increased funding, ongoing progress towards therapies capable of slowing aging or reversing aspects of aging, and a growing taxonomy of such potential therapies and their target mechanisms. The view of aging in the medical community and public at large...
Source: Fight Aging! - December 30, 2022 Category: Research Authors: Reason Tags: Of Interest Source Type: blogs

Fight Aging! Newsletter, December 19th 2022
In conclusion, p16 deletion or p16 positive cell clearance could be a novel strategy preventing long term HFD-induced skin aging. Association of LDL-Cholesterol with Mortality https://www.fightaging.org/archives/2022/12/association-of-ldl-cholesterol-with-mortality/ Researchers here report on a study of LDL-cholesterol and mortality risk in older people. As they note, data on this topic is conflicted once one moves beyond the matter of cardiovascular disease. Over a lifetime, higher LDL-cholesterol makes it easier to reach the tipping point at which cholesterol deposited in blood vessel walls produces en...
Source: Fight Aging! - December 18, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

65 One Sided Relationship Quotes to Help You Find a Way Forward in Your Life
Being in a one sided relationship isn’t fun. You’re there when they need something. A listening ear. A ride to the airport. Kindness and love when times are tough. But when you need something then they don't help out the way you've done. They may not even answer the phone or listen when you're trying to tell them about the tough week you’ve had. If you are in such a situation then I hope these 65 one sided relationship quotes will be helpful for you. To bring you some comfort and make you see you’re not alone. And more importantly, to help you find a healthy way forward starting today. And if you want even more se...
Source: Practical Happiness and Awesomeness Advice That Works | The Positivity Blog - December 6, 2022 Category: Consumer Health News Authors: Henrik Edberg Tags: Inspirational Quotes Personal Development Source Type: blogs

Undisclosed Conflicts of Interest by Physicians Creating the CDC Opioid Prescribing Guidelines: An Epilogue
by Chad D. Kollas, MD, Beverly Schechtman and Carrie JudySeveral important developments have occurred since the publication of our article, “Undisclosed Conflicts of Interest by Physicians Creating the CDC Opioid Prescribing Guidelines: Bad Faith or Incompetence? ” in Pallimed on September 12, 2022 (1). Most notably, this includes the publication of the 2022 CDC Clinical Practice Guideline for Prescribing Opioids for Pain (2), which updated the guidance previously provided by the 2016 CDC Guideline for Prescribing Opioids for Chronic Pain (3). In this epilogue, we will describe those important developments and examine ...
Source: Pallimed: A Hospice and Palliative Medicine Blog - November 29, 2022 Category: Palliative Care Tags: CDC judy kollas opioids schechtman Source Type: blogs

A woman in her 20s with syncope
Written by Destiny Folk MD, with edits by Meyers, peer reviewed by Smith and GrauerA woman in her late 20s with a past medical history of cervical cancer status post chemotherapy and radiation therapy presented to the emergency department for shortness of breath, chest tightness, and two episodes of syncope.Her initial vital signs revealed a temp of 97.7F, HR 125, RR 20, BP 115/90, and an oxygen saturation of 95% on room air. Upon arrival, she did not appear in acute distress. She was noted to be tachycardic and her heart sounds were distant on physical exam. She had a normal respiratory effort, and her lungs were clear to...
Source: Dr. Smith's ECG Blog - November 28, 2022 Category: Cardiology Authors: Pendell Source Type: blogs

How much “ pain ed ” do people need? And what to do when someone is not convinced …
This post has been a long time coming. There’s no doubt that giving explanations about pain mechanisms is common, and that we’ve (health professionals) been doing it a looooong time. Yes, way back to the 1970’s! In the early 1980’s when I started working in this field it was already commonplace to offer people an explanation for chronic pain (and to explain why some pains are such pains, while others bother us less – even when they involve the same degree of nociceptive input). Of course, way back then we used Gate Control Theory (GCT) to explain the distinction between hurt and harm, to explo...
Source: HealthSkills Weblog - November 27, 2022 Category: Anesthesiology Authors: BronnieLennoxThompson Tags: Chronic pain Clinical reasoning Education/CME Research Science in practice biopsychosocial Explain pain pain explanations PNE Therapeutic approaches Source Type: blogs

Forgiveness
Mrs. Dalai was the love of my life, and I had the great honor of sharing the past 36 years with her. I will miss her more than I can possibly describe. She was often a contradiction in terms. She could be shy, she could be brash. She was retiring, she was outgoing. She felt the presence of God, but she didn ’t much like dealing with religion. She was easy to love, and she could be hard to love. But we loved her anyway. Mrs. Dalai and I met on a blind date on July 19, 1986. For me, it was love at first sight. For her, it took a little longer. She didn’t know what to do with me. She kept telling me to go away, and I kept...
Source: Dalai's PACS Blog - November 24, 2022 Category: Radiology Source Type: blogs

Fight Aging! Newsletter, November 21st 2022
In this study researchers added new insight, showing that high-intensity aerobic exercise, which derives its energy from sugar, can reduce the risk of metastatic cancer by as much as 72%. If so far the general message to the public has been 'be active, be healthy', now researchers can explain how aerobic activity can maximize the prevention of the most aggressive and metastatic types of cancer. The study combined an animal model in which mice were trained under a strict exercise regimen, with data from healthy human volunteers examined before and after running. The human data, obtained from an epidemiological study ...
Source: Fight Aging! - November 20, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

What do you think of this " Ventricular Bigeminy " ?
Written by Bobby Nicholson MD, with edits by MeyersA woman in her 50s with past medical history of heart failure, prior stroke, atrial fibrillation on Eliquis, lung cancer in remission, and CKD, presented to the emergency department for evaluation of cough and shortness of breath. EKG was obtained in triage and read as ventricular bigeminy. What do you think?On my first read of the EKG, I agreed with the initial interpretation. Pendell Meyers then recommended that I take a second look at the morphology of the QRS complexes. I think it was easiest for me to see in the rhythm strip, but there are clearly P waves in front of ...
Source: Dr. Smith's ECG Blog - November 19, 2022 Category: Cardiology Authors: Pendell Source Type: blogs

Better Understanding the Outcome of Destroying and Rebuilding the Immune System
The use of chemotherapy to destroy as much of the peripheral immune system as possible, followed by some form of stem cell transplant to rebuild it, has been used for some years as a way to treat multiple sclerosis. In this autoimmune condition, the problem resides in the immune memory, and getting rid of that memory is the solution. The only approach currently demonstrated to work is this somewhat drastic treatment, and the balance of risk and cost means that it is only used for severe diseases such as multiple sclerosis. But in principle, clearance and restoration of the immune system could solve a great many of the issu...
Source: Fight Aging! - November 17, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Global Digital Health 100 – The Medical Futurist ’ s Top Choices in 2022
We first published the list of the Top 100 Digital Health Companies in 2017, highlighting the mindblowing growth the sector registered in the previous year. “Global digital health investments totalled more than 8 billion USD in 2016” – we wrote. Looking at the latest data, we better keep our seatbelts fastened: this figure was USD 57.2 billion in 2021, with a year-on-year growth of 79%. Digital health is booming, with dozens, hundreds of startups and scale-ups entering the realm each year. While their spectacular promises are loud, failure is silent – unless it happens to one of the tech giants ...
Source: The Medical Futurist - November 7, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF bioprinting digital health Healthcare wearables top 100 telemedicine digital health companies remote care digital therapeutics Source Type: blogs