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Federal Aid Creates Central ‐​Planning Power
This study argues that Congress should repeal all federal aid-to-state programs for many reasons, including that aid comes with costly strings attached that destroy local democracy.Richard Epstein and Mario Loyolanoted about aid programs: “When Americans vote in state and local elections, they think they are voting on state and local policies. But often they are just deciding which local officials get to implement the dictates of distant and insulated federal bureaucrats, whom even Congress can’t control.”I came across a table (p. 82) in New Jersey ’s budget that lists the $15 billion the state received in 2020 fro...
Source: Cato-at-liberty - September 4, 2020 Category: American Health Authors: Chris Edwards Source Type: blogs

Fight Aging! Newsletter, August 24th 2020
We report that electrical stimulation (ES) stimulation of post-stroke aged rats led to an improved functional recovery of spatial long-term memory (T-maze), but not on the rotating pole or the inclined plane, both tests requiring complex sensorimotor skills. Surprisingly, ES had a detrimental effect on the asymmetric sensorimotor deficit. Histologically, there was a robust increase in the number of doublecortin-positive cells in the dentate gyrus and SVZ of the infarcted hemisphere and the presence of a considerable number of neurons expressing tubulin beta III in the infarcted area. Among the genes that were unique...
Source: Fight Aging! - August 23, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Centenarians are Comparatively Resistant to Age-Related Disease
Centenarians, people who survive to 100 years of age or more, are comparatively resistant to age-related disease. They are not in good shape in comparison to a much younger person, of course. They are much reduced in vigor and capacity, and aging has gnawed away at their bodies and minds. But nonetheless, the very modest goals of much of the aging research community - to slow aging and extend healthy life span by just a few years - leads to the view that centenarian biochemistry is an interesting place to look for the basis for treatments. If the goal is only a couple more years of life, then why not investigate how it is ...
Source: Fight Aging! - August 20, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, August 10th 2020
This study aimed to characterize the role of BDNF in age-related microglial activation. Initially, we found that degrees of microglial activation were especially evident in the substantia nigra (SN) across different brain regions of aged mice. The levels of BDNF and TrkB in microglia decreased with age and negatively correlated with their activation statuses in mice during aging. Interestingly, aging-related microglial activation could be reversed by chronic, subcutaneous perfusion of BDNF. Peripheral lipopolysaccharide (LPS) injection-induced microglial activation could be reduced by local supplement of BDNF, while shTrkB...
Source: Fight Aging! - August 9, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Mental Health in the Digital Realm
In the time of a global health crisis, when we are asked to close our doors and forced into isolation, we are left feeling deeply uncomfortable and disconnected. We have no option but to sit, stew and stir in our thoughts and emotions. The one thing that is keeping us sane, helping us feel connected and cared for and allowing us to move through the day, is the digital world. The online space is increasingly being recognized as a platform to encourage conversations around mental health. Whether it is noticing symptoms, exploring ways to cope or validating a person’s experience, it has transformed into a tool to champion t...
Source: World of Psychology - August 6, 2020 Category: Psychiatry & Psychology Authors: Rhea Mathews Tags: Friends Minding the Media Racism Relationships Stigma Technology LGBTQ Media Platforms social media Source Type: blogs

Redefining Values in American Health Care
By RICHARD HOEHN, MD Experts claim we could have been better prepared when the COVID-19 pandemic struck in early 2020. With an annual budget of $400-700 million, the Strategic National Stockpile (SNS) is designed to respond to chemical, biological, and other disasters. Its $8 billion inventory included 13,000 ventilators and a limited supply of personal protective equipment, N95 masks, and medical supplies. This left state and local governments scrambling as the COVID-19 pandemic accelerated and the capacity of many hospitals was overwhelmed. Faced with immediate and visible death and suffering, leaders took drastic...
Source: The Health Care Blog - August 6, 2020 Category: Consumer Health News Authors: Christina Liu Tags: Economics Health Policy Healthcare spending Richard Hoen Source Type: blogs

Podcast: My Husband Has Psychosis
  What does psychosis feel like? What’s the difference between a delusion that demons exist and a religious belief of the same? In today’s show, Gabe and Lisa recall Gabe’s real-life psychotic episodes and discuss all the pain and stress surrounding psychosis. Join us as Gabe shares how it felt when there were demons under his bed and when the window washers were watching his every move. (Transcript Available Below) Please Subscribe to Our Show: And We Love Written Reviews!  About The Not Crazy podcast Hosts Gabe Howard is an award-winning writer and speaker who lives with bipolar disorder. He is the auth...
Source: World of Psychology - August 4, 2020 Category: Psychiatry & Psychology Authors: Not Crazy Podcast Tags: Bipolar General Not Crazy Podcast Schizophrenia Source Type: blogs

How Calorie Restriction Improves Intestinal Stem Cell Function
The practice of calorie restriction, eating up to 40% fewer calories while still maintaining an optimal intake of micronutrients, is well demonstrated to slow aging and extend healthy life span in near all species and lineages tested to date. It produces sweeping effects on the operation of metabolism - near everything changes, which has made it something of a challenge to identify the principal points of action. Nonetheless, more efficient operation of the cellular housekeeping mechanisms of autophagy is the most plausible mechanism to account for the majority of the benefits. That calorie restriction fails to extend life...
Source: Fight Aging! - August 3, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Fight Aging! Newsletter, July 13th 2020
In conclusion, sitting for prolonged periods of time without interruption is unfavorably associated with DBP and HDL cholesterol. Exercise Slows Inappropriate Growth of Blood Vessels in a Mouse Model of Macular Degeneration https://www.fightaging.org/archives/2020/07/exercise-slows-inappropriate-growth-of-blood-vessels-in-a-mouse-model-of-macular-degeneration/ Excessive growth of blood vessels beneath the retina is a proximate cause of blindness in conditions such as macular degeneration. Researchers here provide evidence for physical activity to be influential in the pace at which this process of tissue...
Source: Fight Aging! - July 12, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Autoimmune lung disease: Early recognition and treatment helps
A man who was diagnosed with rheumatoid arthritis (RA) five years ago sees his rheumatologist for a follow-up visit. Fortunately, his arthritis is well controlled through medication. He can walk and do all his daily activities without pain. But over the past six months, he’s been feeling short of breath when climbing stairs. He has an annoying dry cough, too. COVID-19? That’s ruled out quickly. But a CT scan of his chest reveals early fibrosis (scarring) of the lungs, most likely related to rheumatoid arthritis. “I can finally walk normally, and now I can’t breathe when I walk!” says the frustrated patient, whose...
Source: Harvard Health Blog - June 24, 2020 Category: Consumer Health News Authors: Paul F. Dellaripa, MD Tags: Arthritis Autoimmune diseases Health Inflammation Lung disease Source Type: blogs

Fight Aging! Newsletter, June 22nd 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - June 21, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Podcast: Using Nature and Animals to Manage Anxiety
 When was the last time you simply enjoyed being in nature? Whether it’s a camping trip to the mountains, a walk in the park or just watching the squirrels from your backyard, being in nature is profoundly healing. In today’s Psych Central Podcast, our guest Richard Louv, a journalist, author and co-founder of the nonprofit Children & Nature Network, discusses the science behind nature’s healing powers. What counts as “nature?” Are pets included? What are some modern barriers to accessing nature, and how can we overcome them? Join us for the answers to these questions and more. SUBSCRIBE & REVIEW Gu...
Source: World of Psychology - May 21, 2020 Category: Psychiatry & Psychology Authors: The Psych Central Podcast Tags: Anxiety and Panic General Green and Environment Interview LifeHelper Mental Health and Wellness Podcast Stress The Psych Central Show Source Type: blogs

Inside Schizophrenia: The Role Nurses Play in Schizophrenia Treatment
Some of the professionals that work most with helping people with schizophrenia are nurses. There are so many types with different skill sets. Host Rachel Star Withers and Co-host Gabe Howards learn who these often overlooked healthcare workers are. Dr. Tari Dilks, Professor and President of the American Psychiatric Nurses Association, joins with insight on what goes into being a psychiatric nurse.  Highlights in “The Role Nurses Play in Schizophrenia Treatment” Episode [01:14] Doctor sidekicks? [04:00] The types of nurses [06:40] Nurse Practitioners [11:00] Nurses specialties [13:00] Psychiatric Nursing [1...
Source: World of Psychology - May 20, 2020 Category: Psychiatry & Psychology Authors: Rachel Star Withers Tags: Inside Schizophrenia Mental Health and Wellness Psychiatry Psychology Mental Disorder Mental Illness Nurses Nursing Psychiatric Nurse Psychotherapy Treatment For Schizophrenia Source Type: blogs

And now for some good news on health
When it comes to health concerns, the COVID-19 pandemic is top of mind for most people right now. And that’s for good reason. But there is some very good non-COVID health news that may not be getting the attention it deserves. According to the CDC, the rates of six of the top 10 causes of death in this country, which account for about three-quarters of all deaths, have been declining. That’s remarkable. And these improvements are occurring despite an aging population and an obesity epidemic that affects several health conditions. Six positive health trends Let’s look at the trends in these conditions and their rank ...
Source: Harvard Health Blog - May 15, 2020 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Cancer Health Health trends Heart Health Source Type: blogs

Fight Aging! Newsletter, May 11th 2020
In this study, we found that older nematodes have higher ROS levels. Interestingly, after hydrogen treatment, the ROS levels were significantly decreased, and hydrogen could significantly extend the lifespans of the N2, sod-3 and sod-5 mutant strains, by approximately 22.7%, 9.5%, and 8.7%, respectively. In addition, aging is regulated by a variety of pathways, such as the insulin signaling pathway, the rapamycin target signaling pathway, and the caloric restriction pathway. However, our results showed that the lifespans of the daf-2 and daf-16 strains, in which these pathways are upregulated, were not affected afte...
Source: Fight Aging! - May 10, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs