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A Recent Update on the Use of Immune Ablation and HSCT to Treat Autoimmunity
For more than twenty years now, Richard Burt's research teams have been working on the treatment of autoimmunity through the destruction and recreation of the immune system. Autoimmunity is a malfunction in the self-tolerance of immune cells, leading them to attack patient tissues. The malfunction is entirely contained in the immune system, so if the immune system is destroyed and replaced, the autoimmunity stops. If the genesis of autoimmunity is happenstance, an unfortunate one-time accident, then this is a cure. But if autoimmunity has a trigger outside the immune system in a given patient, it will return after some per...
Source: Fight Aging! - January 22, 2019 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

5 Good Reasons to Drop Out of College
It’s January. If you are in college, January is a month where you can take a breather. First semester is over. So are the holidays. Now there is time to think. Have you been having doubts? Do you want to return for second semester? It is a choice, you know. There are many good reasons both for personal growth and for long term financial health to stay in school. But college isn’t for everyone. It may not be for you or for you at this time. It’s not only okay but important for the return to second semester to be a conscious, purposeful choice — not be on “automatic.” If you are considering taking a break, yo...
Source: World of Psychology - January 13, 2019 Category: Psychiatry & Psychology Authors: Marie Hartwell-Walker, Ed.D. Tags: Children and Teens College Family Grief and Loss Self-Help Student Therapist Students grieving school preparation social life Time Management Work Life Balance Source Type: blogs

Free Webinar: Identifying Past Trauma Responsible for Current Distress
(Please note: This free live webinar will be recorded and a copy made available to all who registered.) Many adult survivors of childhood trauma go through life struggling with both the immediate as well as latent consequences of having been abused, mentally, physically, or sexually. The chaos and unpredictability characteristic of abuse occurring in childhood, especially by someone the adult survivor trusts can leave survivors deficient in their sense of trust, which is a critical component of healthy development. Students will: Learn how to identify the common characteristics of current struggles associated with a trau...
Source: World of Psychology - January 8, 2019 Category: Psychiatry & Psychology Authors: Gabe Howard Tags: General Mental Health and Wellness Self-Help Webinar Child Abuse Coping Domestic Violence Trauma traumatic experience Source Type: blogs

The Fentanyl Crisis and What You Need to Know
What is Fentanyl? According to the National Institute on Drug Abuse, Fentanyl is a powerful synthetic opioid analgesic that is similar to morphine, but is 50 to 100 times more potent. It is a schedule II prescription drug, and it is typically used to treat patients with severe pain, for side effects surrounding aggressive cancer treatments or to manage pain after major surgery. It can be administered as an injection, a transdermal patch or as a lozenge. Under the medical supervision of a professional, there is little risk for addiction. However, that is not to be overlooked, as any exposure to Fentanyl at all will run the ...
Source: Cliffside Malibu - January 3, 2019 Category: Addiction Authors: Jaclyn Uloth Tags: Addiction Addiction Recovery Addiction to Pharmaceuticals Detox Resources for Alcohol and Drugs/Opiates Drug Rehab Information Drug Treatment Heroin Medical Substance Abuse Synthetic drug abuse drug abuse epidemic fentanyl opioid Source Type: blogs

First Ever Medical Humanities Chat (#MedHumChat)
Hey#medtwitter, I'm toying with the idea of starting a narrative medicine twitter chat. each week we discuss a poem, essay, short story (something very brief!) relevant to medicine and our experience. Would folks be interested? Would you participate? Does this already exist?— Colleen Farrell, MD (@colleenmfarrell)December 16, 2018by Christian Sinclair (@ctsinclair)What started off as a spontaneous tweet by resident Colleen Farrell, MD (@colleenmfarrell) generated a swell of interest from the health care Twitter community and now is being fully realized with the first Medical Humanities chat on Twitter (#MedHumCha...
Source: Pallimed: A Hospice and Palliative Medicine Blog - January 2, 2019 Category: Palliative Care Tags: arts humanities sinclair tweetchat twitter Source Type: blogs

Dander Up, Down, and All Around
Today ' s topics: VA health care politics; a clear-eyed and sane report from a bastion of managerialism, with related observations on innovators trying to create real bottom-up value.It ' s the last day of the year, so let ' s get this done. Owing to various largely unforeseen challenges, happily now largely behind us, this " Dander " series was interrupted for some time. Apologies to anyone who noticed. In any case, to refresh: as Chief Blogger and FIRM president Dr. Poses has indicated often enough in these pages, health care developments raising our dander are still everywhere, all the time, and on the increas...
Source: Health Care Renewal - December 31, 2018 Category: Health Management Source Type: blogs

Fight Aging! Newsletter, December 31st 2018
In conclusion, there are many anti-aging strategies in development, some of which have shown considerable promise for slowing down aging or delaying the onset of age-related diseases. From multiple pre-clinical studies, it appears that upregulation of autophagy through autophagy enhancers, elimination of senescent cells using senolytics, transfusion of plasma from young blood, neurogenesis and BDNF enhancement through specific drugs are promising approaches to sustain normal health during aging and also to postpone age-related diseases. However, these approaches will require critical assessment in clinical trials to determ...
Source: Fight Aging! - December 30, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Medgadget ’s Best Medical Technologies of 2018
The year 2018 is nearly over, and it is time for us to reveal what we believe were the most notable developments in medical technology. We considered a technology’s clinical importance, the greatness of the leap that it’s making over exis...
Source: Medgadget - December 28, 2018 Category: Medical Devices Authors: Editors Tags: Exclusive Medicine Society Surgery Source Type: blogs

Exceptional longevity: why some people live to be more than 100-year old
Interventions that promote longevity, remembered by mnemonic:DEEP purple - “eat colorful plant foods:Dietary modification,Exercise, activeEngagement,Purposeful living (click here toenlarge the image).Based on a Mayo Clinic Proceedings article (https://www.mayoclinicproceedings.org/article/S0025-6196(18)30792-4/):Exceptional Human Longevity: the oldest old have an extreme phenotype of delayed onset of age-related diseases and/or resistance to lethal illnesses occurring earlier in life.Centenarians have delayed onset of chronic diseasesDuring the span of human history the likelihood of living from birth to age 100 rose fro...
Source: Clinical Cases and Images - Blog - December 25, 2018 Category: Universities & Medical Training Tags: Lifestyle Longevity Mayo Clinic Source Type: blogs

Fight Aging! Newsletter, December 24th 2018
In conclusion, we found a gradient of increasing blood pressure with higher levels of BMI. The fact that this gradient is present even in the fully adjusted analyses suggests that BMI may cause a direct effect on blood pressure, independent of other clinical risk factors. PRRX1 as a Possible Point of Control for Remyelination https://www.fightaging.org/archives/2018/12/prrx1-as-a-possible-point-of-control-for-remyelination/ Researchers here outline what is possibly a new point of intervention in the processes that maintain the myelin sheath that wraps nerves. This sheath is vital to the correct operatio...
Source: Fight Aging! - December 23, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Growth Signaling and Aging in Mammals
While the causes of aging are comparatively well mapped, supported by a great deal of solid evidence, the field more than ready for the development of rejuvenation therapies to begin in earnest, the biochemical details of the progression of aging remains a vast and poorly explored forest. This is also true of cellular metabolism as a whole: to fully understand aging, one must fully understand the inner workings of the cell to the finest level of detail. The research community is a lifetime removed from that goal, even taking into account a rapid pace of future progress in the capabilities of biotechnology. Still, so...
Source: Fight Aging! - December 21, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Matters of the Heart
So I guess I ’m going to talk about this thing, which has nothing to do with disability advocacy or Schuyler, except of course it does, because those are the parts of my life that I couldn’t separate from the rest even if I wanted to, and I very much don’t.Last March, as you might remember, I had a hospital scare that ended in me getting my own health regimen back on track. That day sucked, to be sure, and it was followed by plenty more that were also pretty awful. But it ended up for the best, I suppose. I got better and my health improved to a point where it was more solid than it ’s been in years. I ended up tra...
Source: Schuyler's Monster: The Blog - December 17, 2018 Category: Disability Authors: Robert Rummel-Hudson Source Type: blogs

Designer Babies: A Dystopian Sidetrack of Gene Editing
A Chinese scientist shocked the scientific community a couple of days ago with the announcement of having modified the very blueprint of life. If his claims are true, he tried to bestow two baby girls the ability to resist possible future infections with HIV. The outrage shows that humanity is not prepared to utilize the power of gene editing on embryos yet. We have no idea about the biological consequences, and we haven’t tackled the necessary legal and ethical issues. Genes to become toys of the “Gods”? Humanity has come a long way since Aldous Huxley pinned down how methods of genetic engineering, biological cond...
Source: The Medical Futurist - December 15, 2018 Category: Information Technology Authors: nora Tags: Bioethics Future of Medicine Genomics designer babies designer baby Gene gene editing genes Genome genome sequencing Health Healthcare healthcare system Innovation technology Source Type: blogs

A Wee Wiggle in my Journey to Family
You're reading A Wee Wiggle in my Journey to Family, originally posted on Pick the Brain | Motivation and Self Improvement. If you're enjoying this, please visit our site for more inspirational articles. Many of us have faced depression, struggled with low self-esteem, and other debilitating mental health challenges. My own journey with depression was a result of growing up with a rare blood disorder and being told I could never have children of my own. This completely changed my dreams of what family and life meant. Years later I suffered with a rare soft tissue sarcoma, yet, baffling the best of doctors, I survived. I’...
Source: PickTheBrain | Motivation and Self Improvement - December 13, 2018 Category: Consumer Health News Authors: donnagrantwilcox Tags: depression featured psychology self improvement best books Donna Grant Wilcox faith family mental health pickthebrain Source Type: blogs

Fight Aging! Newsletter, December 10th 2018
In conclusion, this is the first report to show that pyroptotic cell death occurs in the aging brain and that the inflammasome can be a viable target to decrease the oxidative stress that occurs as a result of aging. Reducing Levels of Protein Manufacture Slows Measures of Aging in Nematodes https://www.fightaging.org/archives/2018/12/reducing-levels-of-protein-manufacture-slows-measures-of-aging-in-nematodes/ Researchers here demonstrate that an antibiotic slows aging in nematode worms, providing evidence for it to work through a reduction in protein synthesis. Beyond a slowing of aging, one of the con...
Source: Fight Aging! - December 9, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs