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In an Ideal World, How Much Would We Spend on Health Care?
BY BEN WHEATLEY We have heard it said before, and it is no longer shocking to say, that in 2021 the United States spent $4.3 trillion on health care. To put this gaudy number in some perspective, we measure it as a share of our economy and report that health care comprised 18.3% of our gross domestic product. CMS projects that health care will approach 20% of GDP in coming years—one-fifth of everything we buy and sell in this country.  In a recent report, the Health Affairs Council on Health Care Spending and Value said that “it is unclear what percentage of GDP would represent the ideal level to devote to h...
Source: The Health Care Blog - May 11, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Policy Ben Wheatley Health care spending medical debt Patent Source Type: blogs

Nursing the Nation and the World
Nurses are everywhere. They are legion. The ubiquitous nurse is present in the care of children, the elderly, the disabled, and the dying. Nurses don ' t shy away from responsibility — they embrace it. Nurses run towards the metaphorical fire. Just as firefighters rush into burning buildings and police officers run towards the active shooter, nurses don their gloves and deal with the sputum, the blood, the pus, the emesis, the feces, and the urine — body fluids be damned, th ere ' s work to do and nurses do it. The Ubiquitous NurseWhere would the country be without nurses? Without nurses, the healthcare system wou...
Source: Digital Doorway - May 8, 2023 Category: Nursing Source Type: blogs

Fight Aging! Newsletter, April 17th 2023
In conclusion, oral NR altered the gut microbiota in rats and mice, but not in humans. In addition, NR attenuated body fat mass gain in rats, and increased fat and energy absorption in the HFD context. Glycine Supplementation as a Methionine Restriction Mimetic https://www.fightaging.org/archives/2023/04/glycine-supplementation-as-a-methionine-restriction-mimetic/ Supplementation with the non-essential amino acid glycine has been shown to modestly slow aging in short-lived laboratory species. In today's open access review paper, researchers note glycine supplementation as essentially a calorie restrictio...
Source: Fight Aging! - April 16, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fast Facts about Medicare and Social Security
Romina Boccia and Dominik LettMedicare and Social Security are the two largest federal government programs that are also growing the fastest. They are fiscally unsustainable as currently structured. Medicare consists of four parts which provide inpatient care (Part A), outpatient care (Part B), prescription drug coverage (Part D), and subsidies for seniors to choose alternative health insurance providers through Medicare Advantage (Part C). Social Security consists of Old Age and Survivors Insurance (OASI) and Disability Insurance (DI). For the purposes of this fact sheet, Social Security will refer to OASI only. This fact...
Source: Cato-at-liberty - April 13, 2023 Category: American Health Authors: Romina Boccia, Dominik Lett Source Type: blogs

Fight Aging! Newsletter, April 3rd 2023
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - April 2, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Complicating the Relationship Between Cellular Senescence and Late Life Depression
Inflammatory signaling may be influential in major depressive disorder. For any condition in which inflammation is important, attention should be given to the possible role of cellular senescence, given the advent of senolytic therapies to clear these cells. Senescent cells grow in number throughout the body with age, and while never a large fraction of all cells, they energetically generate pro-inflammatory signals. Here, researchers discuss the sometimes there, sometimes not correlation between burden of senescent cells and incidence of major depressive disorder in later life. Previous studies suggested the role...
Source: Fight Aging! - March 30, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Aggrephagy in Hematopoietic Stem Cell Aging
Autophagy is the name given to a complex, varied set of processes that tag and recycle broken or excess proteins and structures in the cell. The destination for materials to be recycled is the lysosome, a membrane-wrapped collection of enzymes capable of breaking down near all of the proteins and other molecules a cell is likely to encounter. How materials are selected and how exactly they make their way to the lysosome varies considerably. Alongside autophagy, the ubiquitin-proteasome system is another way for cells to identify problem proteins, such as those that misfold into toxic configurations, and then break them dow...
Source: Fight Aging! - March 29, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Addressing disparities in gynecological care for women with physical disabilities
I recently read a story in which a woman named H. Lee, who has muscular dystrophy, details a decade-long struggle to receive adequate cervical cancer screening. Providers have been unable to find her cervix due to the curvature of her spine, examined her in her wheelchair because there were no height-adjustable examination tables, and outright Read more… Addressing disparities in gynecological care for women with physical disabilities originally appeared in KevinMD.com.
Source: Kevin, M.D. - Medical Weblog - March 1, 2023 Category: General Medicine Authors: Tags: Policy OB/GYN Primary Care Source Type: blogs

Fight Aging! Newsletter, February 27th 2023
This study tested the hypothesis that ischemic vascular repair in aging by Ang-(1-7) involves attenuation of myelopoietic potential in the bone marrow and decreased mobilization of inflammatory cells. Young or Old male mice of age 3-4 and 22-24 months, respectively, received Ang-(1-7) for four weeks. Myelopoiesis was evaluated in the bone marrow (BM) cells by carrying out the colony forming unit (CFU-GM) assay followed by flow cytometry of monocyte-macrophages. Expression of pro-myelopoietic factors and alarmins in the hematopoietic progenitor-enriched BM cells was evaluated. Hindlimb ischemia (HLI) was induced by ...
Source: Fight Aging! - February 26, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

More Visible Examples of Progress in the Longevity Biotech Industry in 2022
Much of the progress that takes place year after year in any segment of the broader biotech industry is invisible, and the growing portion of that industry focused on aging and longevity is no exception. Biotech is not a high profile industry, particularly because of the heavy dependence on intellectual property and trade secrets as a basis for government-granted monopolies on particular treatments. Details are kept quiet least larger entities in the industry to decide replicate a therapy and call it their own, because the potential rewards are worth the near certainty of a lawsuit. Thus every visible presentation or press...
Source: Fight Aging! - February 22, 2023 Category: Research Authors: Reason Tags: Longevity Industry Source Type: blogs

Tivity Health Acquires Industry Leading Digital Health and Wellness Platform Burnalong
Acquisition will accelerate digital transformation and enhance efforts to support diverse populations and address chronic disease Tivity Health®, a leading provider of healthy life-changing solutions, today announced that it has acquired Burnalong®, a digital health, wellness and fitness platform. The acquisition will accelerate Tivity Health’s efforts to provide consumers with a robust digital platform and extensive health and wellness content, in addition to in-person opportunities through its network of fitness locations. Burnalong will also further enable Tivity Health to support diverse and at-risk populations...
Source: EMR and HIPAA - February 14, 2023 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Burnalong Chronic Disease Management Chronic Diseases Chronic Illness Daniel Freedman Digital Health Fitness and Wellness Health IT Acquisitions Healthcare M&A Mike Kott Richard Ashworth SilverSnea Source Type: blogs

Fight Aging! Newsletter, February 6th 2023
In conclusion, our study reveals that aging enhances atherosclerosis via increased inflammation of visceral fat. Our study suggests that future therapies targeting the visceral fat may reduce atherosclerosis diseaseburden in the expanding older population. Is the Gut a Significant Source of Amyloid-β in Alzheimer's Disease? https://www.fightaging.org/archives/2023/02/is-the-gut-a-significant-source-of-amyloid-%ce%b2-in-alzheimers-disease/ The early stages of Alzheimer's disease are characterized by rising levels of amyloid-β in the brain and the formation of misfolded amyloid aggregates. It is presentl...
Source: Fight Aging! - February 5, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, January 30th 2023
In conclusion, deletion of p16Ink4a cells did not negatively impact beta-cell mass and blood glucose under basal and HFD conditions and proliferation was restored in a subset of HFD mice opening further therapeutic targets in the treatment of diabetes. Communication Between Blood and Brain in Aging and Rejuvenation https://www.fightaging.org/archives/2023/01/communication-between-blood-and-brain-in-aging-and-rejuvenation/ As noted here, joining the circulatory systems of an old and young mouse results in some degree of rejuvenation in the old mouse. Where brain function is improved, researchers are inter...
Source: Fight Aging! - January 29, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Using Design Thinking to Advance SDOH Data Exchange Initiatives
The following is a guest article by Sarah Samis, VP, Public Health Products & Platforms at GCOM. Chronic diseases, which most Americans have at least one of, are the leading causes of death and disability in the U.S. These ongoing and usually incurable diseases account for more than 80% of hospital admissions, 90% of prescriptions filled, and 75% of all physician’s visits. Two-thirds of all deaths are caused by five chronic diseases in particular: heart disease, cancer, stroke, diabetes, and chronic obstructive pulmonary disease.  Preventing and managing chronic disease is not solely a job for an individual and thei...
Source: EMR and HIPAA - January 26, 2023 Category: Information Technology Authors: Guest Author Tags: Analytics/Big Data Communication and Patient Experience Healthcare IT cancer CDC Center for Disease Control Chronic Diseases Chronic Illness Chronic Obstructive Pulmonary Disease Data Exchange Design Thinking diabetes GCOM Heart Source Type: blogs

Considering Autophagy in Long-Lived Species
To what degree is autophagy important in the sizable differences in life span between mammalian species? That is an interesting question. It appears that long-lived species exhibit more effective autophagy, and it also appears that many of the methods of altering metabolism in order to modestly slow aging that were discovered over the past thirty years involve upregulation of autophagy. The effects of calorie restriction on longevity depend upon the correct function of autophagy, and vanish if autophagy is disabled. It is worth noting that autophagy is difficult to measure, however. It involves many distinct process...
Source: Fight Aging! - January 25, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs