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95% of Centenarians are Frail
Survival to 100 years of age is a rarity at the present time, but if the present slow upward trend in life expectancy continues, most people born today will live to 100 or more. That trend will, of course, not continue as-is. The past trend was due to incidental effects of public health measures and general progress in medicine on the mechanisms of aging. The trend in life expectancy will leap upwards with the advent of rejuvenation therapies that deliberately target the reversal and repair of those mechanisms. But that is a topic for another post. Here, let us focus on what actually happens at the present time to p...
Source: Fight Aging! - August 27, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Fight Aging! Newsletter, August 2nd 2021
This study aimed to determine the association between: (i) cognitive decline and bone loss; and (ii) clinically significant cognitive decline on Mini Mental State Examination (MMSE) over the first 5 years and subsequent fracture risk over the following 10 years. A total of 1741 women and 620 men aged ≥65 years from the population-based Canadian Multicentre Osteoporosis Study were followed from 1997 to 2013. Over 95% of participants had normal cognition at baseline. After multivariable adjustment, cognitive decline was associated with bone loss in women but not men. Approximately 13% of participants experienced sign...
Source: Fight Aging! - August 1, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Treating Aging as a Medical Condition Should Long Have Been a Priority
Aging kills most people in the world, and near all people in the wealthier parts of the world. It doesn't just kill, but also produces decades of declining health and capabilities, increased pain and suffering. Addressing the causes of aging, uncovering the mechanisms of aging and treating them, should have been the top priority in medicine ever since the advent of modern antibiotics allowed for control over the majority of infectious disease. Decades in which meaningful progress could have taken place have been wasted, and work on the mechanisms of aging is still only a small field within the life sciences, a small indust...
Source: Fight Aging! - July 23, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

The Fable of the Cats
George SelginThe comparison has by now been made so often that it may qualify as a  platitude. I mean that between stablecoin issuers and “wildcat” banks, the fly‐​by‐​night scams that supposedly flooded the antebellum United States with notes nominally worth some stated amount of gold or silver, but actually worth little more than the rag paper they were made of.Such disreputable stuff, we keep hearing, is what “private” currency always tends to be like. The paper sort survived until federal authorities nationalized the nation’s paper money during the Civil War. And (we are told), digital currency will...
Source: Cato-at-liberty - July 6, 2021 Category: American Health Authors: George Selgin Source Type: blogs

Emerging Trends: Technology ’s Response To Alzheimer’s Disease
In our new series, Emerging Trends, we are looking at those technologies in digital health that are on a particular ‘hype cycle’ – technologies and solutions that currently stand out from the rest because of their novelty, timeliness, or greatness. These are solutions everyone’s talking about or the ones they should. Technological solutions to cognitive decline and Alzheimer’s disease, in particular, are rising with increasing pipeline drug development, promising biomarkers, and more. Let’s jump right in. Liza Marshall was “over the moon” when she said yes to the love of her life in a small cerem...
Source: The Medical Futurist - June 29, 2021 Category: Information Technology Authors: berci.mesko Tags: Forecast Lifestyle medicine Artificial Intelligence in Medicine E-Patients Future of Medicine Personalized Medicine Robotics Telemedicine & Smartphones alzheimer brain diagnosis digital digital health Healthcare Innovation me Source Type: blogs

We Like The Original Versions Of Abstract Artworks More Than Colour-Shifted Ones
By Emma Young Take a look at this 1930 painting, “Rhythm, Joy of Life”, by French artist Robert Delaunay. Do you find it colourful? And do you like it? Robert Delaunay – Rhythm, Joy of Life (1930) Now what if every pixel in a digital version was rotated an equal distance on a “colour wheel” that represents every colour that people can see? Technically, the number of different colours in the image would be the same — but you’d probably perceive it to be less colourful. And, even if you’d never seen the original before, you’d probably like it less.  That, at least, is the con...
Source: BPS RESEARCH DIGEST - June 21, 2021 Category: Psychiatry & Psychology Authors: BPS Research Digest Tags: Perception Source Type: blogs

Fight Aging! Newsletter, April 19th 2021
In conclusion, airway pressure treatment and adherence are independently associated with lower odds of incident AD diagnoses in older adults. Results suggest that treatment of OSA may reduce risk of subsequent dementia.
Source: Fight Aging! - April 18, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

As One Licensed NC Physician To Another Unlicensed One (Dr. Mary Johnson to Dr. Mandy Cohen/NC DHHS Secretary): PROTECT MEDICAL WHISTLEBLOWERS NOW!
Related to mylast post - which went up (after much soul-searching and trepidation) on 2/28/20201 one of the biggest complaints (coming largely from folks reading on mobile phones) was that the post was " so long " .  They wanted something more " concise " . The post relates my own horrific pandemic experience with Central Carolina Hospital/ApolloMD and Duke Lifepoint in Sanford, North Carolina.  It ' s my third dance as a medical whistle-blower in 23 years.  And much like the first two cases (Asheboro in 1998, and ETSU/Ballad Health in 2017), it ' s really NOT " soundbite " material (it would ...
Source: Dr.J's HouseCalls - March 4, 2021 Category: American Health Tags: ApolloMD Central Carolina Hospital CMS Dr. Seuss Duke Lifepoint HIPAA Mandy Cohen Medicaid Medical Whistleblower NCDHHS Pandemic Pediatric Hospitalist Source Type: blogs

Fight Aging! Newsletter, February 8th 2021
This study was divided in two phases: CALERIE-1 and CALERIE-2. CALERIE-1 study was performed to assess the possible effects induced by a reduction of 10-30% of caloric intake on body composition parameters and lipid profile after 6 and 12 months in a population of middle-aged non-obese subjects. CALERIE-1 results showed an improvement in lipid and glycemic profile and a reduction in body weight (BW) and fat mass. CALERIE-2 was the largest multi-center study on CRD. A total of 220 subjects were enrolled randomly with a 2:1 allocation into two subgroups: 145 in the CRD group and 75 in the ad libitum group. The CRD gro...
Source: Fight Aging! - February 7, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Great Transformation
This is the title of a  book published in 1944 by the Hungarian-American political economist Karl Polanyi. It is widely considered to be an important work in political economy, so read it if you can.But the Wikipedia summary actually isn ' t bad. Polanyi addresses many of the problems and issues that concerned Karl Marx, but with 100 years of added perspective, including of course the experience of actually existing Communism. I ' m going to run a trick play here and quote from the Communist Manifesto, which was first published in 1848. (The wordsmithing was actually mostly by Friedrich Engels, who was a better commun...
Source: Stayin' Alive - December 21, 2020 Category: American Health Source Type: blogs

A health librarian at the cinema - Radioactive
Not at the cinema, really, but a DVD, but it was a feature film.The film is about the life and work of Marie Curie, and her work with Pierre Curie.Marie and Pierre, and Henri Becquerel, were awarded the Nobel Prize in 1903.  The film has Pierre reporting that the Nobel Committee did not name Marie on the award.  And that Pierre told them that if they did not name her, he would not accept the award.  I don ' t know if those things were so.  The film does have a scene where Pierre comes back from Stockholm, having accepted the award, and it is clear that Marie has not attended.  R...
Source: Browsing - December 10, 2020 Category: Databases & Libraries Source Type: blogs

Top 10 Online Medical Resources For The Patients Of The Future
There are over 1 billion health-related searches on Google every single day, according to a report. This was about 7% of all searches on the platform before, and no one will be surprised when the 2020 data massively surpasses this number. After all, the internet is likely the first source to turn to with your health-related questions. But which hits are relevant, and which lead to straightforward la la land – even with the best intentions and the best A.I. toolset, the search giant can’t exclude the latter from among the results. And yet, doing so is especially important in the case of medicine and healthcare, s...
Source: The Medical Futurist - December 10, 2020 Category: Information Technology Authors: berci.mesko Tags: Digital Health Research E-Patients Medical Education Medicine social media Webicina webmd gc2 online resources pharmaceutics Topol Mayo Clinic ePatients Medscape Eric Topol Smart Patients Medline Plus National Library of Source Type: blogs

CRAZY AMERICA: Health Insurance Covers Testing When You Are Well But Not When You Are Sick
By HANS DUVEFELT Insurance is the wrong word for what we have here. Our private health insurance system’s prioritization of sometimes frivolous screenings but non-coverage for common illnesses and emergencies is a travesty and an insult to typical American middle class families. State Medicaid insurance for the underemployed has minimal copays of just a few dollars for doctor visits and medications. From my vantage point as a physician, it is the best insurance a patient can have. They cover almost everything and it is clear to me how to apply for exceptions or follow their step care requirements. I cannot...
Source: The Health Care Blog - December 9, 2020 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Physicians Source Type: blogs

Bayes in Medicine
What is Bayesian Analysis and where did it come from? Sometimes referred to as Bayesian Inference in Mathematics, Bayes’ is a method of statistical inference centered around population information, variables, and evidence to determine the probability of a particular event occurring. In essence, it is the mathematical calculation of how likely something is to happen based on the evidence.  The creator of the method was Thomas Bayes –  an 18th century English statistician and Presbyterian minister. Although he did not publish his mathematical theories during his life, the publication of his work was post-humously c...
Source: GIDEON blog - November 5, 2020 Category: Databases & Libraries Authors: Kristina Symes Tags: Epidemiology News Product Source Type: blogs

Doctors Urge Caution in Interpretation of Research in Times of COVID-19
September 9, 2020 To:       American College of Cardiology American College of Chest Physicians American College of Physicians American College of Radiology American Heart Association American Society of Echocardiography American Thoracic Society European Association of Cardiovascular Imaging European Society of Cardiology European Society of Radiology Heart Rhythm Society Infectious Disease Society of America North American Society of Cardiovascular Imaging Radiologic Society of North America Society of Cardiovascular Magnetic Resonance Soci...
Source: The Health Care Blog - September 17, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Medical Practice Patients Physicians myocarditis Saurabh Jha Source Type: blogs