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Drug: Pradaxa

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Total 62 results found since Jan 2013.

How dangerous are NSAIDs in patients with AF?
One of the most commonly asked questions in the office is the treatment of arthritis pain. This comes up because of the concern over taking NSAIDs (non steroidal anti-inflammatory drugs) in patients who are on anticoagulants (such as warfarin, or dabigatran, rivaroxaban, apixaban). My views on this matter have changed. But first, I want to mention a study published in JACC that addressed the issue of NSAID use in pts with AF who take an anticoagulant. This was a sub-analysis of the RELY trial, which pitted dabigatran vs warfarin. Remember, in the original RELY trial, the 150mg dose of dabigatran did better than warfarin at...
Source: Dr John M - July 13, 2018 Category: Cardiology Authors: Dr John Source Type: blogs

NOAC – Cardiology MCQ – Answer
In which of the following conditions non-vitamin K antagonist oral anticoagulants (NOACs) should not be used: Correct answer: c) Mechanical prosthetic valve with atrial fibrillation Subgroup analysis of certain clinical trials support the use of rivaroxaban, apixaban, dabigatran and edoxaban in patients with aortic stenosis, aortic regurgitation or mitral regurgitation patients having atrial fibrillation. NOACs can also be used in aortic bioprosthesis with atrial fibrillation if the valve was implanted more than 3 months back. NOACs are better avoided in those with moderate or severe mitral stenosis and atrial fibrillation...
Source: Cardiophile MD - June 13, 2018 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs

Fighting Hubris in Medicine
By ANISH KOKA The weekend started with a tweet about an elderly man with atrial fibrillation.  Atrial fibrillation is an arrhythmia of the heart that predisposes those who suffer with it to strokes.  The strokes are a  result of clots being thrown from the heart into the brain.  The typical treatment for this condition in those deemed high enough risk is to thin the blood to help prevent these clots from forming, and thus reducing the risk of stroke. 101 year old with a history of a stroke stops his Pradaxa. Only other history hypertension. https://t.co/Ai5z519rcX — Anish Koka (@anish_koka) June 3, 2018 The pro...
Source: The Health Care Blog - June 7, 2018 Category: Consumer Health News Authors: anish_koka Tags: Uncategorized Source Type: blogs

A Tale of 2 FDAs
By ANISH KOKA Frances Oldham Kelsey by all accounts was not mean to have a consequential life.  She was born in Canada in 1914, at a time women were meant to be seen and not heard.  Nonetheless, an affinity for science eventually lead to a masters in pharmacology from the prestigious McGill University.  Her first real break came after she was accepted for PhD level work in the pharmacology lab of a professor at the University of Chicago.  An esteemed professor was starting a pharmacology lab and needed assistants, and the man from Canada seemed to have a perfect resume to fit.  That’s right, I said man.  France...
Source: The Health Care Blog - June 4, 2018 Category: Consumer Health News Authors: anish_koka Tags: Uncategorized Source Type: blogs

MKSAP: 26-year-old woman with a mechanical mitral valve prosthesis
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 26-year-old woman with a mechanical mitral valve prosthesis visits to discuss anticoagulation management during pregnancy. Her last menstrual period was 6 weeks ago and her pregnancy was confirmed by laboratory testing in the office. Her mitral valve was replaced 5 years ago. Her medications are low-dose aspirin, metoprolol, and warfarin (4 mg/d). On physical examination, vital signs are normal. Cardiac auscultation demonstrates a normal mechanical S1. There are no murmurs or added sounds. Her INR is 2.6. Whic...
Source: Kevin, M.D. - Medical Weblog - February 24, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/mksap" rel="tag" > mksap < /a > Tags: Conditions Cardiology OB/GYN Source Type: blogs

Taking an anticlotting drug? If you need a procedure, be prepared
Millions of people with cardiovascular disease take drugs that help prevent blood clots, which can lodge in a vessel and choke off the blood supply to part of a leg, lung, or the brain. These potentially lifesaving medications include warfarin (Coumadin) and a class of drugs called non-vitamin K antagonist oral anticoagulants or NOACs. Examples include dabigatran (Pradaxa) and rivaroxaban (Xarelto). However, if you’re taking one of these drugs and need an invasive procedure — anything from a tooth extraction to a hip replacement — managing the risks can be tricky, says cardiologist Dr. Gregory Piazza, assistant profe...
Source: Harvard Health Blog - November 1, 2017 Category: Consumer Health News Authors: Julie Corliss Tags: Drugs and Supplements Health Heart Health Surgery anticlotting drug anticlotting drugs Source Type: blogs

Cardiology MCQ Test 5
Time limit: 0 Quiz-summary 0 of 20 questions completed Questions: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Information This test series requires login for attempting. You can login easily with your Facebook account (Use the CONNECT WITH icon on the upper part of right sidebar displaying t...
Source: Cardiophile MD - October 22, 2017 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Statins, Like All Medicines, Are Neither Good Nor Bad
We have to talk about drugs. No, not illicit drugs, but medications used by doctors and patients. Plaintiff attorneys run ads on TV that fool people into thinking certain meds are bad. The current one I deal with is the clot-blocking drug rivaroxaban (Xarelto.) Before that, it was dabigatran (Pradaxa). If, or when, the makers of rivaroxaban settle a class action suit, you can bet apixaban (Eliquis) will be next. These ads are a problem because they use fear persuasion (see Scott Adams’ blog), and because they can induce patients to stop taking or not starting a beneficial medicine.  Lots of other medications suffer ...
Source: Dr John M - April 30, 2017 Category: Cardiology Authors: Dr John Source Type: blogs

Small Clots on Replacement Aortic Valves Deserve Attention
This study, like all good studies, raises many questions for future study. I look forward to learning more about this issue. This discovery also highlights the challenge of making progress in cardiology. It’s hard work. I may be wrong, but it’s likely we are in a period of slow incremental progress. JMM Related posts: Possible clot issue on replacement aortic valves slows momentum of TAVR Why shouldn’t Cardiology lead the way in shared decsion-making? The top three Cardiology stories of 2010…and three predictions for 2011
Source: Dr John M - April 6, 2017 Category: Cardiology Authors: Dr John Source Type: blogs

Antidote for dabigatran – Cardiology MCQ
Which of the following is an antidote for dabigatran? a) Abciximab b) Idarucizumab c) Infliximab d) None of the above Correct answer: b) Idarucizumab Abciximab is an antiplatelet agent (glycoprotein Iib/IIIa antagonist) and infliximab is a tumor necrosis factor alpha (TNF-α) antagonist used in the treatment of autoimmune disorders.
Source: Cardiophile MD - March 9, 2017 Category: Cardiology Authors: Johnson Francis Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs

2017 update on the changing use of “blood thinners” for AF
Times have changed in the treatment of patients with atrial fibrillation (AF). First some background: The first of the four pillars of AF care is stroke prevention. The only proven means to protect patients with AF from stroke is use of drugs that block clotting factors–or anticoagulants. Some people call these drugs blood thinners. I don’t. That’s because they don’t thin the blood. They inhibit proteins in the blood that form clots; viscosity of the blood is not affected. Blockade of clotting factors works because static blood in the fibrillating (non-contractile) atria increases the probability of...
Source: Dr John M - February 13, 2017 Category: Cardiology Authors: Dr John Source Type: blogs

Say No to Watchman
Cardiology is on the brink of making a big mistake. We have embraced a new procedure called left atrial appendage isolation. You may be seeing the ads for a device called Watchman. Like this one> The appendage-closure idea was a good one: during atrial fibrillation (AF), blood can pool in the left atrial appendage, and this promotes clot formation. (The LA appendage has many nooks and crannies.) So… if we could put a device in there, see image, this would block clots from getting out and causing stroke.  Also, once the device has been in for months, the body walls it off and the patient can stop the anticoagulan...
Source: Dr John M - November 10, 2016 Category: Cardiology Authors: Dr John Source Type: blogs

Drugs approved for treatment of normotensive patients with pulmonary embolism
Heparin Fondaparinux Rivaroxaban Apixaban Dabigatran Edoxaban Thrombolytic therapy is reserved for rescue in case of decompensation due to right ventricular failure or recurrence of pulmonary embolism in these stable patients.
Source: Cardiophile MD - August 31, 2016 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiology Source Type: blogs

Welcome to my World: Perpetual Alarm Fatigue
By HANS DUVEFELT, MD Part of a series on primary care challenges and their solutions. I missed a drug interaction warning the other day when I prescribed a sulfa antibiotic to Barton, a COPD patient who is also taking dofetilide, an uncommon antiarrhythmic. The pharmacy called me to question the prescription, and I quickly changed it to a cephalosporin. The big red warning had popped up on my computer screen, but I x-ed it away with my right thumb on the trackball without reading the warning. Quite honestly, I am so used to getting irrelevant warnings that it has become a reflex to bring the cursor to the spot where I can ...
Source: The Health Care Blog - August 15, 2016 Category: Consumer Health News Authors: John Irvine Tags: Uncategorized Source Type: blogs

DM / DNB Cardiology Entrance New Test Series 4
Time limit: 0 Quiz-summary 0 of 30 questions completed Questions: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 ...
Source: Cardiophile MD - July 16, 2016 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiology MCQ DM / DNB Cardiology Entrance Featured Source Type: blogs