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Weekly Australian Health IT Links – 1 August, 2022.
Here are a few I have come across the last week or so. Note: Each link is followed by a title and a few paragraphs. For the full article click on the link above title of the article. Note also that full access to some links may require site registration or subscription payment.General Comment-----Quite a lot this week – especially regarding the NBN and Labor trying to regain control of what it is actually for – service provision – and not making a huge profit – in their view. Love the new Minister has ambitions to be maximally photogenic and not a ‘techie’!Otherwise all sorts of fun things!-----https://www.ausd...
Source: Australian Health Information Technology - August 1, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
Fight Aging! Newsletter, August 1st 2022
In this study, we used the recently released Infinium Mouse Methylation BeadChip to compare such epigenetic modifications in C57BL/6 (B6) and DBA/2J (DBA) mice. We observed marked differences in age-associated DNA methylation in these commonly used inbred mouse strains, indicating that epigenetic clocks for one strain cannot be simply applied to other strains without further verification. Interestingly, the CpGs with highest age-correlation were still overlapping in B6 and DBA mice and included the genes Hsf4, Prima1, Aspa, and Wnt3a. Furthermore, Hsf4, Aspa, and Wnt3a revealed highly significant age-associated DNA methyla...
Source: Fight Aging! - July 31, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
July 28, 2022 Edition-----Sadly the war drags on, Biden seems to be pretty impotent on most policy fronts and the US seems to be heading into a recession. Not good,In the UK the choosing the next PM is off and running as the country and Europe are cooling down after a heatwave (for them) of biblical proportions!In OZ Parliament is meeting which is when the rubber will really hit the road as a new virus wave runs out of control still! We need to do more to control it as we realise just how bad long COVID is!-----Major Issues.-----https://www.afr.com/policy/economy/how-a-nobel-laureate-got-australian-economists-offside-...
Source: Australian Health Information Technology - July 28, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
Fight Aging! Newsletter, July 4th 2022
This study showed that centenarians had very specific changes in CD4+ T cell populations, which were manifested by an elevated Th17/Treg ratio in vivo, as well as a changed secretory phenotype. Although the T cells of centenarians cannot resist the aging-related expression of proinflammatory genes, their secretory phenotype was altered, explaining the relatively low level of inflammation in centenarians. These results suggested the presence of a mechanism to ameliorate inflammaging in centenarians. This may be achieved by reversing the imbalance of Th17/Treg cells and reducing pro-inflammatory cytokines.
Longevit...
Source: Fight Aging! - July 3, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, January 17th 2022
In conclusion, fibroblasts in monolayers cultured with soluble pentosidine and tridimensional in vitro skin constructs exposed to the combination of AGEs and UVA promote an inflammatory state and an alteration of the dermal compartment in relation to an elastosis-like environment.
Source: Fight Aging! - January 16, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, January 3rd 2022
In this study, we showed that the iPaD (inducing Plagl2 and anti-Dyrk1a) lentivirus substantially rejuvenated the proliferative and neurogenic potential of NSCs in the aged brain. Clonal analysis by a sparse labeling approach as well as transcriptome analysis indicated that iPaD can rejuvenate aged NSCs (19-21 mo of age) to a level comparable with those at 1 or 2 months of age and successfully improved cognition of aged mice.
Once rejuvenated and activated by iPaD, aged dormant NSCs can generate, on average, 4.9 neurons but very few astrocytes in 3-week tracing. Furthermore, these activated NSCs were maintained for ...
Source: Fight Aging! - January 2, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Immune-Boosting Hacks to Remember as the World Reopens
You might think the pandemic has ended by the way many people behave. However, threats remain for many, including the unvaccinated and the immunocompromised.
Even if you are otherwise healthy, the novel coronavirus isn’t the only germ against which you need to protect yourself. Please follow these eight immune-boosting hacks as society reopens.
1. Eat a Healthy Diet
A plant-based diet rich in antioxidants and other vital nutrients is your best bet for providing your body with the requisite building blocks for ongoing health. The phytonutrients contained in plants neutralize toxins from pollution, bacteria and vi...
Source: PickTheBrain | Motivation and Self Improvement - June 28, 2021 Category: Consumer Health News Authors: Kara Reynolds Tags: featured health and fitness philosophy self education self-improvement covid protection virus Source Type: blogs
Do A & P Textbooks Have Too Much Content? | TAPP 94
Oh, thathuge A&P textbook I teach from! Do I really need tocover all of it? Host Kevin Patton discusses his take on this age-old problem. Does thecolor of my marking pen send a signal that I don't want to send to my students? A breakthrough in understandinghow teeth sense cold. And what in the world is atunneling nanotube—and can I get one at my local hardware store?Greek names for SARS-CoV-2 variants simplifies conversation and avoids stigma.00:00 | Introduction00:43 | How Do Teeth Sense Cold?07:04 | Sponsored by AAA08:32 | Red& Green for Student Feedback18:03 | What's a TNT?23:52 | Sponsored by HAPI25...
Source: The A and P Professor - June 7, 2021 Category: Physiology Authors: Kevin Patton Source Type: blogs
Fight Aging! Newsletter, March 29th 2021
Discussion of Systemic Inflammation and its Contribution to Dementia
Fisetin Reduces D-Galactose Induced Cognitive Loss in Mice
Reprogramming Cancer Cells into Normal Somatic Cells
Considering Longevity Medicine and the Education of Physicians
Researchers Generate Thyroid Organoids Capable of Restoring Function in Mice
In Search of Transcriptional Signatures of Aging
A Pace of Aging Biomarker Correlates with Manifestations of Aging
Targeting Tissues with Extracellular Vesicles
Calorie Restriction Slows Aging of the Gut Microbiome in Mice
Mitochondrial DNA Heteroplasmy in the Aging Heart
Evidence for Hea...
Source: Fight Aging! - March 28, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, March 1st 2021
This study may have important implications for preventing cell senescence and aging-induced tendinopathy, as well as for the selection of novel therapeutic targets of chronic tendon diseases.
Our results showed that the treatment of bleomycin, a DNA damaging agent, induced rat patellar TSC (PTSC) cellular senescence. The senescence was characterized by an increase in the senescence-associated β-galactosidase activity, as well as senescence-associated changes in cell morphology. On the other hand, rapamycin could extend lifespan in multiple species, including yeast, fruit flies, and mice, by decelerating DNA damage ...
Source: Fight Aging! - February 28, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Through the Looking Glass: Microscopic Structures in Many Sizes
We seldom see microscopic objects next to one another, so it can be difficult to picture how they compare. For instance, it might surprise you that a thousand cold-virus particles could line up across one human skin cell! The largest objects that scientists view through microscopes are about a millimeter (roughly the size of a poppyseed), and they’re about 10 million times larger than the smallest molecules scientists can view: atoms.
This insightful Cell Size and Scale interactive from the Genetic Science Learning Center at the University of Utah helps put the size of many biological structures in context. Suppor...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - February 17, 2021 Category: Research Authors: Matt Mills Tags: Cells Molecular Structures Bacteria Proteins Viruses Source Type: blogs
Laws Against Discussing Pandemics, Cont ’d: Privacy
Walter OlsonIwrote last week in this space about government ’s longstanding tendency during dangerous outbreaks of contagious disease to assert control over public discussion of medical matters on the rationale of preventing the spread of misinformation. (Some members of Congressare currently trying to browbeat platforms into taking down social media posts that promote erroneous notions about vaccines.) Citing the flu pandemic of 1918 –19, I pointed out that “rather than quieting the rumor mill and the popular spread of false ideas about the virus, the tight control of information [often does] the reverse.”The...
Source: Cato-at-liberty - February 8, 2021 Category: American Health Authors: Walter Olson Source Type: blogs
What a Year! | Pandemic Teaching & More | A Reflection | TAPP 86
Discussions that matter. In our private space, we can have the vulnerability needed for authentic, deep discussions. Discussions not limited to a sentence or two at a time.No ads. No spam. No fake news. No thoughtless re-shares. Just plain old connection with others who do what you do!Privacy. The A&P Professor community has the connectivity of Facebook and Twitter, but the security of a private membership site. None of your information can be shared outside the community, so you can share what you like without it being re-shared to the world. Like your dean, for instance. In our community, you can share your frustrati...
Source: The A and P Professor - January 27, 2021 Category: Physiology Authors: Kevin Patton Source Type: blogs
