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Sore arm and chills after the COVID vaccine? Will Tylenol or NSAIDs such as Motrin or Aleve lower vaccine efficacy?
This is a common question, "I have a sore arm and chills after the COVID vaccine? Will taking Tylenol or NSAIDs such as Motrin or Aleve lower vaccine efficacy?".The short answer is, no. You can take antipyretic analgesics (Tylenol, and NSAIDs such as Motrin or Aleve), if needed, to control symptoms after a COVID immunization. Ideally, do not take the medications before the vaccine. You can take them, if needed, after the vaccine. The details are below. Antipyretic analgesics (Tylenol, and NSAIDs such as Motrin, Aleve) are widely used to ameliorate vaccine adverse reactions. Observational studies reporting on antipyretic us...
Source: Clinical Cases and Images - Blog - January 15, 2021 Category: Universities & Medical Training Tags: Vaccines Source Type: blogs

Fight Aging! Newsletter, January 11th 2021
This study demonstrates the potential of a natural (o-Vanillin) and a synthetic (RG-7112) senolytic compounds to remove senescent IVD cells, decrease SASP factors release, reduce the inflammatory environment and enhance the IVD matrix production. Removal of senescent cells, using senolytics drugs, could lead to improved therapeutic interventions and ultimately decrease pain and a provide a better quality of life of patients living with intervertebral disc degeneration and low back pain. From Ying Ann Chiao of Oklahoma Medical Research Foundation: Mitochondrial dysfunction plays a central role in aging and cardiovasc...
Source: Fight Aging! - January 10, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Wondering about COVID-19 vaccines if you ’re pregnant or breastfeeding?
Now that COVID-19 vaccines are rolling out, pregnant and breastfeeding people have many questions around risks and benefits. At first, many of those receiving vaccines in US will be healthcare workers, although the circles for vaccine eligibility are widening. The Centers for Disease Control and Prevention (CDC), the American College of Obstetrics and Gynecology (ACOG), and the Society for Maternal-Fetal Medicine agree that the new mRNA COVID-19 vaccines should be offered to pregnant and breastfeeding individuals who are eligible for vaccination. Here are answers to some basic questions you may have about getting a COVID-1...
Source: Harvard Health Blog - January 7, 2021 Category: Consumer Health News Authors: Ilona T. Goldfarb, MD, MPH Tags: Coronavirus and COVID-19 Health Parenting Pregnancy Prevention Vaccines Source Type: blogs

Fight Aging! Newsletter, January 4th 2021
The objective of this study is to quantify the overall and cancer type-specific risks of subsequent primary cancers (SPCs) among adult-onset cancer survivors by first primary cancer (FPC) types and sex. Among 1,537,101 survivors (mean age, 60.4 years; 48.8% women), 156,442 SPC cases and 88,818 SPC deaths occurred during 11,197,890 person-years of follow-up (mean, 7.3 years). Among men, the overall risk of developing any SPCs was statistically significantly higher for 18 of the 30 FPC types, and risk of dying from any SPCs was statistically significantly higher for 27 of 30 FPC types as compared with risks in the general po...
Source: Fight Aging! - January 3, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

A Look Back at 2020: Progress Towards the Treatment of Aging as a Medical Condition
While I suspect that COVID-19 will feature prominently in most retrospectives on 2020, I'll say only a little on it. The data on mortality by year end, if taken at face value, continues to suggest that the outcome will fall at the higher end of the early estimates of a pandemic three to six times worse than a bad influenza year, ten times worse than a normal influenza year. The people who die are near entirely the old, the co-morbid, and the immunocompromised. They die because they are suffering the damage and dysfunction of aging. Yet the societal conversation and the actions of policy makers ignore this. There is ...
Source: Fight Aging! - December 31, 2020 Category: Research Authors: Reason Tags: Of Interest Source Type: blogs

Fight Aging! Newsletter, December 28th 2020
In conclusion, our study demonstrated that the molecular processes of aging are relatively subtle in their progress, and the aging process of every tissue depends on the tissue's specialized function and environment. Hence, individual gene or process alone cannot be described as the key of aging in the whole organism. Mouse Age Matters: How Age Affects the Murine Plasma Metabolome A large part of metabolomics research relies on experiments involving mouse models, which are usually 6 to 20 weeks of age. However, in this age range mice undergo dramatic developmental changes. Even small age differences may l...
Source: Fight Aging! - December 27, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Should you take the Covid-19 Vaccine if You ’re Pregnant?
(Updated 12/27/20) The FDA took an important step on Friday by authorizing the Emergency Use for Pfizer-BioNTech’s COVID-19 vaccine. Recognizing the risks inherent in COVID-19 infection can be significant, while those identified to date for its vaccine appear to be low, they have not advised against vaccination during pregnancy. However, its important to note that have they not specifically approved the vaccine for use in pregnancy. That’s because we have only limited animal and human data on use of the COVID-19 vaccine during pregnancy or breastfeeding. This is incredibly frustrating to those of us ...
Source: The Blog That Ate Manhattan - December 13, 2020 Category: Primary Care Authors: Margaret Polaneczky, MD Tags: Uncategorized Covid-19 pfizer pregnancy pregnant Vaccine Source Type: blogs

Should you take the Covid-19 Vaccine if You ’ re Pregnant?
(Updated 12/27/20) The FDA took an important step on Friday by authorizing the Emergency Use for Pfizer-BioNTech’s COVID-19 vaccine. Recognizing the risks inherent in COVID-19 infection can be significant, while those identified to date for its vaccine appear to be low, they have not advised against vaccination during pregnancy. However, its important to note that have they not specifically approved the vaccine for use in pregnancy. That’s because we have only limited animal and human data on use of the COVID-19 vaccine during pregnancy or breastfeeding. This is incredibly frustrating to those of us ...
Source: The Blog That Ate Manhattan - December 13, 2020 Category: Primary Care Authors: Margaret Polaneczky, MD Tags: Uncategorized Covid-19 pfizer pregnancy pregnant Vaccine Source Type: blogs

Should you take the Covid-19 Vaccine if You ’re Pregnant?
The FDA took an important step on Friday by authorizing the Emergency Use for Pfizer-BioNTech’s COVID-19 vaccine. Recognizing the risks inherent in COVID-19 infection can be significant, while those identified to date for its vaccine appear to be low, they have not advised against vaccination during pregnancy. However, its important to note that have they not specifically approved the vaccine for use in pregnancy. That’s because we have neither animal or human data on use of the COVID-19 vaccine during pregnancy or breastfeeding. This is incredibly frustrating to those of us who care from women of repro...
Source: The Blog That Ate Manhattan - December 13, 2020 Category: Primary Care Authors: Margaret Polaneczky, MD Tags: Uncategorized Covid-19 pfizer pregnancy pregnant Vaccine Source Type: blogs

Grimacing Or Smiling Can Make An Injection Feel Less Painful
By Emma Young If you’re preparing to receive a flu vaccine — or even a COVID-19 vaccine — this winter, you’ll be interested in the results of a new study that investigates whether it’s better to smile or grimace your way through the pain of an injection. The idea that manipulating our facial expressions can affect our emotions has a long and storied history. There are many advocates of this “facial feedback hypothesis”, and many critics, too. Indeed, one of the classic findings in the field — that people find cartoons funnier if they hold a pen between their teeth, inducing a smile — recent...
Source: BPS RESEARCH DIGEST - December 1, 2020 Category: Psychiatry & Psychology Authors: BPS Research Digest Tags: Emotion Faces Source Type: blogs

Can the Government Mandate a Covid-19 Vaccine? Will It Have To?
Conclusion As governments assess how to contend with reaching effective levels of vaccination, they are preparing to tread carefully around vaccine skepticism while transparently and apolitically addressing common concerns about safety and due process. Attitudes could change as vaccines are distributed to the public and, hopefully, demonstrate safety and effectiveness, encouraging individuals to rapidly vaccinate. For government, a heavy-handed approach could backfire, fueling further anti-government/anti-science sentiment, but not pursuing vaccination with ample vigor could mean a prolonged timeline for co...
Source: The Health Care Blog - November 23, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Health Policy COVID-19 vaccine Phillip Meylan Source Type: blogs

Fight Aging! Newsletter, November 23rd 2020
In conclusion, the study indicates that HBOT may induce significant senolytic effects that include significantly increasing telomere length and clearance of senescent cells in the aging populations. Data on the Prevalence of Liver Fibrosis in Middle Age https://www.fightaging.org/archives/2020/11/data-on-the-prevalence-of-liver-fibrosis-in-middle-age/ Fibrosis is a consequence of age-related disarray in tissue maintenance processes, leading to the deposition of scar-like collagen that disrupts tissue structure and function. It is an ultimately fatal issue for which there are only poor treatment options a...
Source: Fight Aging! - November 22, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Overhyping the Effects of Hyperbaric Oxygen Treatment on Aging
In conclusion, the study indicates that HBOT may induce significant senolytic effects including significantly increasing telomere length and clearance of senescent cells in the aging populations.
Source: Fight Aging! - November 20, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs