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Infectious Disease: Influenza
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Total 929 results found since Jan 2013.
We Should Actually Try to Treat Aging for a Change
I am generally in favor of the sentiment offered in this commentary on recent clinical trial failures for the first attempts to guide anti-aging technologies through the FDA gauntlet, which is that researchers and developers should be aiming to treat aging, not specific age-related diseases. There is likely to be a greater incidence of failure on the way to the clinic, and for entirely avoidable reasons, if everyone is attempting to force a more or less square peg into a more or less round hole.
Longevity trials: time to change the approach?
Following the recent clinical trial failures by Unity Biotechnolog...
Source: Fight Aging! - September 8, 2020 Category: Research Authors: Reason Tags: Politics and Legislation Source Type: blogs
Federal Aid Creates Central ‐Planning Power
This study argues that Congress should repeal all federal aid-to-state programs for many reasons, including that aid comes with costly strings attached that destroy local democracy.Richard Epstein and Mario Loyolanoted about aid programs: “When Americans vote in state and local elections, they think they are voting on state and local policies. But often they are just deciding which local officials get to implement the dictates of distant and insulated federal bureaucrats, whom even Congress can’t control.”I came across a table (p. 82) in New Jersey ’s budget that lists the $15 billion the state received in 2020 fro...
Source: Cato-at-liberty - September 4, 2020 Category: American Health Authors: Chris Edwards Source Type: blogs
Announcing The COVID-19 Symptom Data Challenge
By FARZAD MOSTASHARI
In Partnership with Resolve to Save Lives, Carnegie Mellon University, and University of Maryland, Catalyst @ Health 2.0 is excited to announce the launch of The COVID-19 Symptom Data Challenge. The COVID-19 Symptom Data Challenge is looking for novel analytic approaches that use COVID-19 Symptom Survey data to enable earlier detection and improved situational awareness of the outbreak by public health and the public.
How the Challenge Works:
In Phase I, innovators submit a white paper (“digital poster”) summarizing the approach, methods, analysis, findings, relevant figures and graphs ...
Source: The Health Care Blog - September 1, 2020 Category: Consumer Health News Authors: matthew holt Tags: COVID-19 Data Health Policy challenge Facebook Source Type: blogs
FDA Determined Convalescent Plasma Is Safe, Leaves Decisions on Efficacy up to Clinicians/ Patients. That’s the Way It Should Always Be
Jeffrey A. SingerYesterday the Food and Drug Administration released a clinical memorandum giving Emergency Use Authorization for COVID-19 Convalescent Plasma (CCP) therapy, a previously unapproved biological product. Forseveral months clinicians treating severely ill COVID-19 patients have transfused plasma donated by convalescing COVID-19 patients, rich with the antibodies to the virus produced by their immune system, hoping that these same antibodies can help patients suffering from active infection. Early results have been promising but, as somecritics of the FDA decision have stated, more data is needed befo...
Source: Cato-at-liberty - August 24, 2020 Category: American Health Authors: Jeffrey A. Singer Source Type: blogs
Fight Aging! Newsletter, August 24th 2020
We report that electrical stimulation (ES) stimulation of post-stroke aged rats led to an improved functional recovery of spatial long-term memory (T-maze), but not on the rotating pole or the inclined plane, both tests requiring complex sensorimotor skills. Surprisingly, ES had a detrimental effect on the asymmetric sensorimotor deficit.
Histologically, there was a robust increase in the number of doublecortin-positive cells in the dentate gyrus and SVZ of the infarcted hemisphere and the presence of a considerable number of neurons expressing tubulin beta III in the infarcted area. Among the genes that were unique...
Source: Fight Aging! - August 23, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Towards Better Vaccines and a Lower Burden of Infectious Disease in Old People
Over a lifetime, the burden of infectious disease - and particularly persistent infections such as cytomegalovirus - influences the pace of aging via its detrimental impact on immune function in later life. The slow upward trend in life expectancy over the past two centuries is due in no small part to reductions in infectious disease that accompanied improvements in sanitation and then medicine. In addition, in old age, once the immune system declines into ineffectieness, infectious disease becomes a much more serious concern. Infections that a young person defeats with ease become life-threatening. The primary strategy to...
Source: Fight Aging! - August 17, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Why spiritual health is so important for medical students
A tale of two pandemics: Around the time of the coronavirus outbreak, 2019 also marked a full century since the death of Sir William Osler, who revolutionized medical training. Despite some lingering debate over whether Dr. Osler ’s pneumonia-related death should be counted among the 50 million lost to the 1918 influenza pandemic, his notes suggest […]Find jobs at Careers by KevinMD.com. Search thousands of physician, PA, NP, and CRNA jobs now. Learn more.
Source: Kevin, M.D. - Medical Weblog - August 14, 2020 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/elizabeth-j-berger" rel="tag" > Elizabeth J. Berger, APBCC < /a > < /span > Tags: Conditions COVID-19 coronavirus Infectious Disease Source Type: blogs
Fight Aging! Newsletter, August 10th 2020
This study aimed to characterize the role of BDNF in age-related microglial activation. Initially, we found that degrees of microglial activation were especially evident in the substantia nigra (SN) across different brain regions of aged mice. The levels of BDNF and TrkB in microglia decreased with age and negatively correlated with their activation statuses in mice during aging. Interestingly, aging-related microglial activation could be reversed by chronic, subcutaneous perfusion of BDNF. Peripheral lipopolysaccharide (LPS) injection-induced microglial activation could be reduced by local supplement of BDNF, while shTrkB...
Source: Fight Aging! - August 9, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Vaccines save lives
August is National Immunization Awareness Month (NIAM) and this year vaccines and immunology are probably on many more people’s minds than usual – for obvious reasons. While medical professionals and researchers work tirelessly on developing and testing a COVID-19 vaccine (amongst others), let’s briefly remind ourselves how far we have come in such a brief segment of human history.
224 years, 40 vaccines
The first vaccine, developed in 1796 for smallpox, was not put into mass production until many years later – but was a monumental breakthrough in Medicine. It took almost another 100 years before the next vaccines ...
Source: GIDEON blog - August 6, 2020 Category: Databases & Libraries Authors: Kristina Symes Tags: News Source Type: blogs
Influenza Vaccine Use Correlates with Lower Risk of Alzheimer ' s Disease
Researchers here note a correlation between receiving influenza vaccination, even once, and the later risk of Alzheimer's disease. This is interesting in the context of the present debate over the mechanisms of Alzheimer's, particularly regarding whether or not persistent viral infection is an important driver of the condition. Inflammation and immune system dysfunction are also clearly important in the progression of neurodegenerative conditions. How exactly influenza vaccines might influence this complex decline is an open question. One might hypothesize that this is mediated by something other than biology - that people...
Source: Fight Aging! - August 3, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Post #51 Our Family ’s School Decision Making Process
My boys do not want to wear pants.A small factor, but part of the reason they campaigned for remote learning. My daughter, who generally prefers clothing, remained on the fence.The remote vs. in-person learning decision has so many different factors it is very difficult as a pediatrician to give families a single clear answer.As new data emerges, it further confounds a family ’s decision that seemed crystal clear just 2 internet articles ago.Several people have asked point blank, “What are you doing for your own kids?”If I have left your text unanswered or have not replied to your email or Facebook comment, I apologi...
Source: A Pediatrician's Blog - August 1, 2020 Category: Pediatrics Source Type: blogs
COVID herd immunity: At hand or forever elusive?
By MICHEL ACCAD, MD
With cases of COVID-19 either disappeared or rapidly diminishing from places like Wuhan, Italy, New York, and Sweden, many voices are speculating that herd immunity may have been reached in those areas and that it may be at hand in the remaining parts of the world that are still struggling with the pandemic. Lockdowns should end—or may not have been needed to begin with, they conclude. Adding plausibility to their speculation is the discovery of biological evidence suggesting that prior exposure to other coronaviruses may confer some degree of immunity against SARS-CoV2, a...
Source: The Health Care Blog - July 30, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Health Policy immunity MICHEL ACCAD Pandemic Source Type: blogs
The Dual Epidemics of COVID-19 and Influenza: Vaccine Acceptance, Coverage, and Mandates
Lawrence O. Gostin (Georgetown University), Daniel Salmon (Johns Hopkins University), The Dual Epidemics of COVID-19 and Influenza: Vaccine Acceptance, Coverage, and Mandates, JAMA Online (2020): The confluence of coronavirus disease 2019 (COVID-19) and seasonal influenza this fall and winter will...
Source: HealthLawProf Blog - July 24, 2020 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs
Post #50 School Reopening during the COVID-19 Pandemic
There is probably a no more emotionally charged topic of discussion currently than that of school reopening this fall. And for good reason - nearly everyone has a stake in it.Society is concerned because of the real risk of increased community spread.Teachers are concerned because of the COVID-19 risk to themselves and how the logistics of school will directly affect their livelihood and stress level as they have to constantly adjust to the barrage of changes and duties. Families are concerned because of the COVID-19 risk to their children and to those living at home. Not to mention, many depend on school to allow for...
Source: A Pediatrician's Blog - July 23, 2020 Category: Pediatrics Source Type: blogs
Vaccines for COVID-19 moving closer
As the world reels from illnesses and deaths due to COVID-19, the race is on for a safe, effective, long-lasting vaccine to help the body block the novel coronavirus SARS-CoV-2. The three vaccine approaches discussed here are among the first to be tested clinically in the United States.
How vaccines induce immunity: The starting line
In 1796, in a pastoral corner of England, and during a far more feudal and ethically less enlightened time, Edward Jenner, an English country surgeon, inoculated James Phipps, his gardener’s eight-year-old son, with cowpox pustules obtained from the arm of a milkmaid. It was widely believed ...
Source: Harvard Health Blog - July 21, 2020 Category: Consumer Health News Authors: Shiv Pillai, PhD, MBBS Tags: Coronavirus and COVID-19 Health Infectious diseases Vaccines Source Type: blogs
