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Infectious Disease: Influenza

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Total 929 results found since Jan 2013.

TWiV 878: Shape matters sometimes
TWiV revisits chronic wasting disease of cervids and the ability of the prions to infect meadow voles and raccoons, and the suggestion that stochastic assembly of influenza virus particles may play a role in phenotypic diversity.
Source: virology blog - March 20, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology cervid chronic wasting disease influenza virus prion transmissible spongiform encephalopathy viral viruses Source Type: blogs

Whither Covid?
I recommend this Twitter thread by John Burn-Murdoch, as most Americans and their political leaders have apparently decided that the pandemic is over. It isn ' t, although here in the U.S. we are in a better place than we were a year ago. In a nutshell, new cases and hospitalizations are rising in much of the world, including much of Europe. This isn ' t so much because of loosened mitigation measures, but because of the emergence of a new variant, Omicron B.A2 which is evidently even more contagious than the original Omicron and perhaps a bit better at getting around existing immunity. It ' s just starting to show up...
Source: Stayin' Alive - March 18, 2022 Category: American Health Source Type: blogs

The (sort of, partial) Father mRNA Vaccines Who Now Spreads Vaccine Misinformation (Part 2)
By DAVID WARMFLASH, MD This is part 2 of David Warmlash’s takedown of Robert W. Malone’s appearance (transcript) on the Rogan podcast. Part 1 is here Menstruation and Fertility Much more than the line about reproductive damage in the Wisconsin News clip that we used to open the story, Malone used the Rogan interview to dive more deeply into the topic, starting with:  …there’s a huge number of dysmenorrhea and menometrorrhagia… By that, he meant excessive menstrual cramping and very heavy, often irregular, bleeding, which he followed up with: …they DENY it… Judging by other parts ...
Source: The Health Care Blog - March 18, 2022 Category: Consumer Health News Authors: matthew holt Tags: COVID-19 Health Policy antivaxxer COVID-19 vaccine David Warmflash Joe Rogan Robert Malone Source Type: blogs

Microfluidic Device for Quick and Accurate SARS-CoV-2 Testing
Researchers at the Institute of Photonic Sciences in Barcelona, Spain, have created a microfluidic chip that can detect the SARS-CoV-2 virus in less than 30 minutes, and with a similar level of accuracy as the current gold-standard test, PCR. The tec...
Source: Medgadget - March 1, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Diagnostics Public Health Source Type: blogs

‘Just Follow the Science’ Shows Some Improvement
Peter Van DorenDuring summer 2020 I wrote anessay about what science can and cannot do and the role it can play in public policy decisions including those pertaining to the COVID-19 pandemic. I concluded that science explains relationships between cause and effect: no more and no less. No normative conclusions about individual or collective decisions follow directly from science. Instead, costs, benefits, and other values properly enter both individual and collective decisions.I have writtenthreetimessince then about gradual recognition of this argument among medical professionals as well as journalists. I a...
Source: Cato-at-liberty - February 16, 2022 Category: American Health Authors: Peter Van Doren Source Type: blogs

Photographing the Physics of Cells
Dr. Melike Lakadamyali with a microscope. Credit: Courtesy of Dr. Lakadamyali. “It would be a dream come true if I could look at a cell within a tissue and have a Google Maps view to zoom in until I saw individual molecules,” says Melike Lakadamyali, Ph.D., an associate professor of physiology at the University of Pennsylvania’s Perelman School of Medicine in Philadelphia. Her lab is helping make part of that dream a reality by developing super-resolution microscopy tools that visualize cells at a near-molecular level. Blending Physics and Biology Science and math fascinated Dr. Lakadamyali since childhood, ...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - February 2, 2022 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Cells Tools and Techniques Cellular Imaging Cellular Processes Cool Tools/Techniques Profiles Source Type: blogs

Avian influenza (bird flu)
My local park has notices up about an outbreak.  Here are sources of latest official information (for the UK).  Travel related information is at the end of the post. In addition to the sites below try your local authority ' s website.Animal and Plant Health Agency reports relating to wild birdsDEFRA and APHA, preliminary outbreak assessment, for Europe, Russia and the UK - includes Weekly disease reportsDEFRA and APHA, guidanceDepartment of Agriculture, Environment and Rural Affairs (Northern Ireland), Avian influenzaHealth and Safety Executive, Avian influenza(PDF) (information particularly for those i...
Source: Browsing - January 26, 2022 Category: Databases & Libraries Tags: avian influenza Source Type: blogs

Fight Aging! Newsletter, January 17th 2022
In conclusion, fibroblasts in monolayers cultured with soluble pentosidine and tridimensional in vitro skin constructs exposed to the combination of AGEs and UVA promote an inflammatory state and an alteration of the dermal compartment in relation to an elastosis-like environment.
Source: Fight Aging! - January 16, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Senescent Cells Negatively Affect T Helper Cell Differentiation
The accumulation of senescent cells with age harms tissues and cell behavior throughout the body. Senescent cells generate a pro-growth, pro-inflammation mix of molecules, the senescence-associated secretory phenotype (SASP). Researchers are still comparatively early in the process of producing a complete list of problems caused by the SASP. One of the better studied SASP components is TGF-β, and here researchers demonstrates that it causes disarray in the normal behavior of T-helper cells of the adaptive immune system. Applying senolytic treatments that selectively destroy senescent cells can reverse this aspect of aging...
Source: Fight Aging! - January 13, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

A brief note on epidemiology
Mark Sumner at DK has aroundup of news from overwhelmed health care systems around the country. This seems to be getting very little attention from national media, for some reason -- this is a list of local stories, which don ' t seem to have gotten the attention of editors at CNN or the New York Times.This is definitely bad news in the present, but it ' s better news in the long run. The Covid-19 variant that ' s causing this is extremely contagious -- as contagious a measles, apparently. That means you can become infected just by briefly being in the vicinity of an infectious person. One thing that ' s really unpleasant ...
Source: Stayin' Alive - January 8, 2022 Category: American Health Source Type: blogs

Fight Aging! Newsletter, January 3rd 2022
In this study, we showed that the iPaD (inducing Plagl2 and anti-Dyrk1a) lentivirus substantially rejuvenated the proliferative and neurogenic potential of NSCs in the aged brain. Clonal analysis by a sparse labeling approach as well as transcriptome analysis indicated that iPaD can rejuvenate aged NSCs (19-21 mo of age) to a level comparable with those at 1 or 2 months of age and successfully improved cognition of aged mice. Once rejuvenated and activated by iPaD, aged dormant NSCs can generate, on average, 4.9 neurons but very few astrocytes in 3-week tracing. Furthermore, these activated NSCs were maintained for ...
Source: Fight Aging! - January 2, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Towards More Broadly Effective Influenza Vaccines
Might it be possible to develop a vaccine that works on every strain of influenza, rather than going through a seasonal exercise of vaccination every year? Or at least many strains, rather than just a few? In today's research materials, scientists discuss a possible approach, identifying a novel part of the influenza virus to target, a part of the viral structure that may mutate less readily than the usual vaccine targets. Viruses mutate aggressively when they infect large population, a challenge to both vaccination and natural immunity. The immune system recognizes small parts of a virus, epitopes, and the epitopes most r...
Source: Fight Aging! - December 30, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Flu Virus-Inspired Nanoparticles for mRNA Delivery
Researchers at the University of California San Diego developed a new delivery technique for mRNA. The method involves flu virus-inspired nanoparticles that can escape endosomes, the acidic vesicles that engulf and destroy materials that attempt to e...
Source: Medgadget - December 13, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Genetics Medicine Nanomedicine Public Health flu mRNA vaccine UCSD Source Type: blogs

Fight Aging! Newsletter, December 13th 2021
In conclusion, there is a good amount of pre-clinical and clinical data showing a strong positive correlation between reduction of senescent cells frequencies and functional improvement of skin. Whether senescence of skin cells makes a significant causal contribution to skin ageing can still not be conclusively decided, however. Nonetheless, there is strong evidence existing today to assume that better understanding of cell senescence in skin may lead to a breakthrough in interventions into skin ageing. Isomerization of Tau May be Involved in Alzheimer's Disease https://www.fightaging.org/archives/2021/12/isome...
Source: Fight Aging! - December 12, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Innovation, mRNA, and Public Policy
Chris EdwardsThe main weapons against COVID-19 are the vaccines developed by Moderna and BioNTech after a decade of their research into mRNA technologies. That research was supported by more than $3 billion of private angel investment and venture capital.Democrats and Republicans both support medical research funding, and Republicans tout the Trump administration ’s Operation Warp Speed. But governments were not the key to mRNA development. Instead, we can thank the leaders and scientists at Moderna and BioNTech and the suppliers of private capital to them, as I discusshere andhere.TheWall Street Journal ’s A...
Source: Cato-at-liberty - December 6, 2021 Category: American Health Authors: Chris Edwards Source Type: blogs