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Fight Aging! Newsletter, April 3rd 2017
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more.
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Source: Fight Aging! - April 2, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, March 27th 2017
In conclusion, DNAm of multiple disease-related genes are strongly linked to mortality outcomes.
The recently established epigenetic clock (DNAm age) has received growing attention as an increasing number of studies have uncovered it to be a proxy of biological ageing and thus potentially providing a measure for assessing health and mortality. Intriguingly, we targeted mortality-related DNAm changes and did not find any overlap with previously established CpGs that are used to determine the DNAm age. Our findings are in line with evidence, suggesting that DNAm involved in ageing or health-related outcomes are mostly...
Source: Fight Aging! - March 26, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
A Demonstration of Chimeric Tissue Farming: Mouse Pancreatic Tissue Grown in Rats
We examined them closely for the presence of any rat cells, but we found that the mouse's immune system had eliminated them. This is very promising for our hope to transplant human organs grown in animals because it suggests that any contaminating animal cells could be eliminated by the patient's immune system after transplant." Importantly, the researchers also did not see any signs of tumor formation or other abnormalities caused by the pluripotent mouse stem cells that formed the islets. Tumor formation is often a concern when pluripotent stem cells are used in an animal due to the cells' remarkable developmental plasti...
Source: Fight Aging! - January 26, 2017 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
The Case for Defeating Death by Aging
This flashy popular press article in the modern style of scrolling illustrates an important point: that it is actually quite difficult for newcomers to build a coherent picture from the varied claims and lines of research taking place in the field of longevity science. The thing that they are missing, and which takes some time to put together for yourself, is enough of an understanding of the underlying biology to make estimates of likelihood of success for given project versus the plausible scale of the outcome. Will it produce a lengthening of life or postponement of age-related disease, and for how long? Absent this und...
Source: Fight Aging! - January 19, 2017 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
The Technological Future of Surgery
The future of surgery offers an amazing cooperation between humans and technology, which could elevate the level of precision and efficiency of surgeries so high we have never seen before.
Will we have Matrix-like small surgical robots? Will they pull in and out organs from patients’ bodies?
The scene is not impossible. It looks like we have come a long way from ancient Egypt, where doctors performed invasive surgeries as far back as 3,500 years ago. Only two years ago, Nasa teamed up with American medical company Virtual Incision to develop a robot that can be placed inside a patient’s body and then controlled rem...
Source: The Medical Futurist - January 17, 2017 Category: Information Technology Authors: nora Tags: Future of Medicine Medical Augmented Reality Medical Robotics Virtual Reality in Medicine 3d printing AI artificial intelligence diagnostics gc4 Surgery surgical robot technology Source Type: blogs
What We Learnt in Digital Health in 2016
In order to successfully move into 2017, it is crucial to draw the lessons of the past year in terms of successes, failures, remaining challenges and impenetrable obstacles in the field of digital health. Food for thought!
An impulsive year in science and healthcare
2016 was a bold, busy and impulsive year in science and healthcare. Elon Musk, CEO of Tesla, founder of SpaceX and great visionary raised the stakes in astronautics again for the greatest pleasure of the fans of space flights. He promised no less than to take humanity to Mars as soon as possible (I explored the medical challenges of the project here). In July, ...
Source: The Medical Futurist - December 20, 2016 Category: Information Technology Authors: nora Tags: Future of Medicine artificial intelligence artificial pancreas big data Boston Dynamics digital health food scanner GC1 google Innovation precision medicine robotics theranos trackers virtual reality wearables Source Type: blogs
A Reasonable Perspective on Cryonics
In this article, one of the scientists involved in our rejuvenation research community outlines a very reasonable view on cryonics and cryopreservation. Cryonics is the low-temperature preservation of at least the brain following death, done these days with the use of cryoprotectants and vitrifiction to minimize ice crystal formation. It offers an unknown chance at a future restoration to life: technology marches onwards year after year, and for so long as the structures that encode the data of the mind are preserved, there is the possibility of living again in a future age that has mastered the technologies needed for res...
Source: Fight Aging! - December 2, 2016 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, September 26th 2016
This study included 647 patients 80 to 106 years of age who had audiometric evaluations at an academic medical center (141 had multiple audiograms). The degree of hearing loss was compared across the following age brackets: 80 to 84 years, 85 to 89 years, 90 to 94 years, and 95 years and older. From an individual perspective, the rate of hearing decrease between 2 audiograms was compared with age. The researchers found that changes in hearing among age brackets were higher during the 10th decade of life than the 9th decade at all frequencies for all the patients (average age, 90 years). Correspondingly, the annual rate of ...
Source: Fight Aging! - September 25, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, September 19th 2016
In conclusion, we found that IS status was associated with a significant increase in Hannum DNA methylation, likely as a consequence of the accumulation of cardiovascular risk factors, and near signification with Horvath method. Patients with IS were biologically older than controls, a difference that was more obvious in young stroke. This could open up the possibility of useful new biomarker of stroke risk.
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A Profile of Kelsey Moody and Ichor Therapeutics
https://www.fightaging.org/archives/2016/09/a-profile-of-kelsey-moody
Source: Fight Aging! - September 18, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
A Visual Introduction to SENS Rejuvenation Research
The SENS Research Foundation has assembled a set of narrated cellular biochemistry animations that serve as an introduction to the various distinct projects that make up the field of rejuvenation biotechnology. The videos outline the forms of cell and tissue damage that are the root cause of aging and age-related disease, as well as the classes of therapy that could, once constructed, either repair that damage or bypass it entirely. Since aging is exactly an accumulation of damage and the consequences of that damage, repair of the damage is the basis for rejuvenation, the reversal and prevention of degenerative aging and a...
Source: Fight Aging! - September 15, 2016 Category: Research Authors: Reason Tags: Activism, Advocacy and Education Source Type: blogs
The Most Over-Hyped Technologies in Healthcare
The hype about the technological development in healthcare should not blind you in terms of the probabilities and possibilities of today’s healthcare and the future of medicine. In order to remain objective, conscious but optimistic, let’s look at the most over-hyped technologies and keep in mind the realistic development opportunities in healing.
You know the saying: the pessimist says the glass is half empty, the optimist says it is half full, and, well, the cynic asks who drank the other half? I’m truly an optimist – especially when it comes to the future of medicine and healthcare.
And although my optimism is ...
Source: The Medical Futurist - September 13, 2016 Category: Information Technology Authors: nora Tags: Future of Medicine 3d printing GC1 Healthcare hype organs robotics technology theranos virtual reality wearables Source Type: blogs
Fight Aging! Newsletter, September 12th 2016
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more.
This content is...
Source: Fight Aging! - September 11, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, September 5th 2016
This study is a good example of the degree to which the choice to remain active in later life makes a difference. That implies a range of other choices over the decades in order to raise the odds that you can in fact choose to remain active when older, such as avoiding weight gain.
Moderate physical activity is associated with a greater than 50% reduction in cardiovascular death in over-65s. The 12 year study in nearly 2500 adults aged 65 to 74 years found that moderate physical activity reduced the risk of an acute cardiovascular event by more than 30%. High levels of physical activity led to greater risk reducti...
Source: Fight Aging! - September 4, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The Potential Use of Cell Therapies to Treat Immunosenescence
Immunosenescence is the name given to the decline of immune system effectiveness with aging, a large component of the frailty that arises in later life. This decline is partially a result of a failing supply of new immune cells, and partially a result of a growing misconfiguration of the immune system as a whole, driven by life-long exposure to infections. On this second front, persistent infection by herpesviruses such as cytomegalovirus appears to be particularly problematic, the cause of large fractions of the immune cell population in an old individual becoming specialized and unable to react to new threats. This open ...
Source: Fight Aging! - August 30, 2016 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, August 29th 2016
This study demonstrates that TNTs play a significant part in the intercellular transfer of α-synuclein fibrils and reveals the specific role of lysosomes in this process. This represents a major breakthrough in understanding the mechanisms underlying the progression of synucleinopathies. These compelling findings, together with previous reports from the same team, point to the general role of TNTs in the propagation of prion-like proteins in neurodegenerative diseases and identify TNTs as a new therapeutic target to combat the progression of these incurable diseases.
Shorter Period of Rapamycin Treatment in Mice...
Source: Fight Aging! - August 28, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
