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‘Just Follow the Science’ Shows Some Improvement
Peter Van DorenDuring summer 2020 I wrote anessay about what science can and cannot do and the role it can play in public policy decisions including those pertaining to the COVID-19 pandemic. I concluded that science explains relationships between cause and effect: no more and no less. No normative conclusions about individual or collective decisions follow directly from science. Instead, costs, benefits, and other values properly enter both individual and collective decisions.I have writtenthreetimessince then about gradual recognition of this argument among medical professionals as well as journalists. I a...
Source: Cato-at-liberty - February 16, 2022 Category: American Health Authors: Peter Van Doren Source Type: blogs

Lessons of pandemic : Tackling Covid is much easier task, than the onslaught of Science !
This article  by Dr. Anand Krishnan, Professor of  community medicine, AIIMS New Delhi, has some enlightening content https://timesofindia.indiatimes.com/india/whys-pandemic-policymaking-still-short-of-science/articleshow/88650912.cms
Source: Dr.S.Venkatesan MD - February 12, 2022 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized Source Type: blogs

The Social Science of Covid
By MIKE MAGEE As we enter the third year of the Covid pandemic, with perhaps a partial end in sight, the weight of the debate shows signs of shifting away from genetically engineered therapies, and toward a social science search for historic context. Renowned historian, Charles E. Rosenberg, envisioned a similar transition for the AIDS epidemic in 1989. He described its likely future course then as a “social phenomenon” with these words, “Epidemics start at a moment in time, proceed on a stage limited in space and duration, follow a plot line of increasing and revelatory tension, move to a crisis of individual ...
Source: The Health Care Blog - January 31, 2022 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Policy COVID-19 COVID-19 vaccine Mike Magee vaccines Source Type: blogs

The next plague
Here ' s a discussion by Kelly Piper of the ominous implications of the Omicron variant of Covid-19. Most people are thinking that in the long run, it ' s good news that we have this highly contagious, but less virulent strain of the virus. Once we get past the surge and the problems of overwhelmed hospitals and too many people out sick, we ' ll have a degree of herd immunity and it will be comparable to flu and other respiratory viruses that we already live with.That may be true, although it ' s too soon to tell. Another more dangerous variant may yet emerge. But it also points to a danger -- this highly contagious virus ...
Source: Stayin' Alive - January 28, 2022 Category: American Health Source Type: blogs

Vortioxetine for Post-COVID Brain Fog
If you ' re relatively young and healthy, is a mild case of COVID-19 really “mild”, like a cold or the flu? Are you still at risk forlong COVID— a persistent state of fatigue, anxiety, insomnia, exercise intolerance, and “brain fog” (impairments in memory, attention, and concentration)— even if you ' re fully vaccinated?If you have post-COVID brain fog and live in Toronto, you might beeligible for a clinical trial run by the Brain and Cognition Discovery Foundation. The study will assess the effects ofvortioxetine (brand name Trintellix), an FDA-approved antidepressant thatmay improve cognitive function in peop...
Source: The Neurocritic - January 17, 2022 Category: Neuroscience Authors: The Neurocritic Source Type: blogs

5 COVID-19 Discussions That Will Dominate 2022
Discussions That Will Dominate 2022 appeared first on The Medical Futurist.
Source: The Medical Futurist - January 11, 2022 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: Covid-19 Forecast Artificial Intelligence in Medicine Science Fiction vaccination pandemic vaccine pfizer fatigue booster Source Type: blogs

Diverting children from unnecessary hospital attendances in York
NHS Confederation -Local GP provider organisation Nimbuscare worked with the local authority, volunteers, local businesses and health providers in York to turn an area of wasteland into the beginnings of a health village. The disused car park hosts an innovative paediatric hub pilot scheme to help prevent under-fives from going into hospital, provides preventative health checks and delivers flu, Covid-19 and booster vaccinations on behalf of the eleven GP practices within the city. Case studyMore detail
Source: Health Management Specialist Library - January 11, 2022 Category: UK Health Authors: The King ' s Fund Library Tags: Primary and community care Source Type: blogs

A brief note on epidemiology
Mark Sumner at DK has aroundup of news from overwhelmed health care systems around the country. This seems to be getting very little attention from national media, for some reason -- this is a list of local stories, which don ' t seem to have gotten the attention of editors at CNN or the New York Times.This is definitely bad news in the present, but it ' s better news in the long run. The Covid-19 variant that ' s causing this is extremely contagious -- as contagious a measles, apparently. That means you can become infected just by briefly being in the vicinity of an infectious person. One thing that ' s really unpleasant ...
Source: Stayin' Alive - January 8, 2022 Category: American Health Source Type: blogs

Some thoughts on Omicron and COVID19 in the last week or so
  Some recent Tweets and threads from me on Omicron and related topicsI am dismayed by the people, including leaders, who are treating#Omicron as " mild "& therefore not a big deal ignoring the unvaccinated& unboosted, long covid, at risk groups and that it is not " mild " for everyone, just on average has less severe effects to the vaccinated Jonathan Eisen (@phylogenomics)January 5, 2022If you are citing something written by Monica Gandhi on COVID please read this and other threads pointing out just how many times she has been wrong wrong wrong and wrong.https://t.co/XJcJ2kytlt Jonathan Eisen (@phylogenomi...
Source: The Tree of Life - January 7, 2022 Category: Microbiology Source Type: blogs

Fight Aging! Newsletter, January 3rd 2022
In this study, we showed that the iPaD (inducing Plagl2 and anti-Dyrk1a) lentivirus substantially rejuvenated the proliferative and neurogenic potential of NSCs in the aged brain. Clonal analysis by a sparse labeling approach as well as transcriptome analysis indicated that iPaD can rejuvenate aged NSCs (19-21 mo of age) to a level comparable with those at 1 or 2 months of age and successfully improved cognition of aged mice. Once rejuvenated and activated by iPaD, aged dormant NSCs can generate, on average, 4.9 neurons but very few astrocytes in 3-week tracing. Furthermore, these activated NSCs were maintained for ...
Source: Fight Aging! - January 2, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Towards More Broadly Effective Influenza Vaccines
Might it be possible to develop a vaccine that works on every strain of influenza, rather than going through a seasonal exercise of vaccination every year? Or at least many strains, rather than just a few? In today's research materials, scientists discuss a possible approach, identifying a novel part of the influenza virus to target, a part of the viral structure that may mutate less readily than the usual vaccine targets. Viruses mutate aggressively when they infect large population, a challenge to both vaccination and natural immunity. The immune system recognizes small parts of a virus, epitopes, and the epitopes most r...
Source: Fight Aging! - December 30, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Flu Virus-Inspired Nanoparticles for mRNA Delivery
Researchers at the University of California San Diego developed a new delivery technique for mRNA. The method involves flu virus-inspired nanoparticles that can escape endosomes, the acidic vesicles that engulf and destroy materials that attempt to e...
Source: Medgadget - December 13, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Genetics Medicine Nanomedicine Public Health flu mRNA vaccine UCSD Source Type: blogs

Fight Aging! Newsletter, December 13th 2021
In conclusion, there is a good amount of pre-clinical and clinical data showing a strong positive correlation between reduction of senescent cells frequencies and functional improvement of skin. Whether senescence of skin cells makes a significant causal contribution to skin ageing can still not be conclusively decided, however. Nonetheless, there is strong evidence existing today to assume that better understanding of cell senescence in skin may lead to a breakthrough in interventions into skin ageing. Isomerization of Tau May be Involved in Alzheimer's Disease https://www.fightaging.org/archives/2021/12/isome...
Source: Fight Aging! - December 12, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Innovation, mRNA, and Public Policy
Chris EdwardsThe main weapons against COVID-19 are the vaccines developed by Moderna and BioNTech after a decade of their research into mRNA technologies. That research was supported by more than $3 billion of private angel investment and venture capital.Democrats and Republicans both support medical research funding, and Republicans tout the Trump administration ’s Operation Warp Speed. But governments were not the key to mRNA development. Instead, we can thank the leaders and scientists at Moderna and BioNTech and the suppliers of private capital to them, as I discusshere andhere.TheWall Street Journal ’s A...
Source: Cato-at-liberty - December 6, 2021 Category: American Health Authors: Chris Edwards Source Type: blogs

Cytomegalovirus Harmfully Alters Immune Cell Populations in the Aging Immune System
The aging of the immune system isn't just a matter of becoming vulnerable to commonplace infectious diseases, such as influenza. The immune system also removes senescent cells and cancerous cells, both of which present sizable risks to health in later life. Additionally, immune cells participate in normal tissue maintenance in a variety of ways. Further, the chronic inflammation characteristic of an aged immune system disrupts the normal function of many types of cell and tissue, contributing to a diverse range of age-related conditions. For most people, cytomegalovirus (CMV) is an apparently innocuous persistent he...
Source: Fight Aging! - December 6, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs