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The Year of Living Dangerously
It ' s been exactly one year since our lives changed. On March 10, 2020, Governor Charlie Baker declared a state of emergency for Massachusetts, changing the way many of us travel. On March 11, 2020, the World Health Organization declared COVID-19 a global pandemic, its first such designation since declaring H1N1 influenza a pandemic in 2009. On March 15, 2020, I flew to Minnesota and prepared my Rochester apartment for a lockdown. I said my goodbyes to colleagues on March 16 and flew back to Boston. We ' ve run the Mayo Clinic Platform at a distance for the past year.During the pandemic, those old enough to have overcome ...
Source: Life as a Healthcare CIO - March 16, 2021 Category: Information Technology Source Type: blogs

Fight Aging! Newsletter, March 1st 2021
This study may have important implications for preventing cell senescence and aging-induced tendinopathy, as well as for the selection of novel therapeutic targets of chronic tendon diseases. Our results showed that the treatment of bleomycin, a DNA damaging agent, induced rat patellar TSC (PTSC) cellular senescence. The senescence was characterized by an increase in the senescence-associated β-galactosidase activity, as well as senescence-associated changes in cell morphology. On the other hand, rapamycin could extend lifespan in multiple species, including yeast, fruit flies, and mice, by decelerating DNA damage ...
Source: Fight Aging! - February 28, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

On the Aging Adaptive Immune System
An interesting fact about the adaptive immune system: the number of T cells in the body remains much the same across the entire lifespan, even after the supply of new T cells all but ceases in middle age. T cells are created as thymocytes by hematopoietic cells in the bone marrow, and then mature in the thymus. The supply of new cells from the bone marrow is negatively affected by age, while the thymus atrophies, active tissue becoming replaced with fat. Lacking replacements, the T cell population in the body becomes increasingly exhausted, senescent, and otherwise damaged. Many T cells become inappropriately specialized t...
Source: Fight Aging! - February 26, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

This Is How We Can End COVID In 6 Steps
There is frankly one question today on everybody’s mind: when will all this end? And although deep inside we all know this won’t really be over till it’s… over, we strive for a definite answer. Say, in June. The sad news is, the pandemic will be with us until we finally take individual responsibility. Instead of trying to avoid the jab, we should get ourselves vaccinated as soon as possible. Why? I’ll tell you in six simple, self-explanatory logical steps. 1. COVID-19 will end when the coronavirus becomes endemic A virus becomes endemic when it has a constant presence within a population in a certain ar...
Source: The Medical Futurist - February 25, 2021 Category: Information Technology Authors: Judit Kuszkó Tags: Covid-19 Digital Health Research E-Patients Healthcare ethical vaccination coronavirus lockdown vaccine flu hospitals Italy Spanish flu Source Type: blogs

This Is How We Can End COVID In 6 Logical Steps
There is frankly one question today on everybody’s mind: when will all this end? And although deep inside we all know this won’t really be over till it’s… over, we strive for a definite answer. Say, in June. The sad news is, the pandemic will be with us until we finally take individual responsibility. Instead of trying to avoid the jab, we should get ourselves vaccinated as soon as possible. Why? I’ll tell you in six simple, self-explanatory logical steps. 1. COVID-19 will end when the coronavirus becomes endemic A virus becomes endemic when it has a constant presence within a population in a certain ar...
Source: The Medical Futurist - February 25, 2021 Category: Information Technology Authors: Judit Kuszkó Tags: Covid-19 Digital Health Research E-Patients Healthcare ethical vaccination coronavirus lockdown vaccine flu hospitals Italy Spanish flu Source Type: blogs

The Feds ’ Sorry Record on COVID-19
David BoazThey say journalism is the first rough draft of history. With the Covid pandemic now a year old, we are starting to seebooks on the topic. And variouslibertarianstudies andarticles, critically examining government andprivate-sector responses to the crisis, have appeared. But some of those rough drafts in the major media add up to a pretty strong critique of government failure by themselves. Just consider the disappointing, even tragic, analyses that have been appearing over the past year:The federal government hadreports andwarnings andwar games aboutpandemic danger at least as far back as 2001, butwas apparently...
Source: Cato-at-liberty - February 24, 2021 Category: American Health Authors: David Boaz Source Type: blogs

Fight Aging! Newsletter, February 22nd 2021
In conclusion, long term LRIC could decrease blood pressure and ameliorate vascular remodeling via inflammation regulation. The Damage of a Heart Attack Causes the Immune System to Overreact https://www.fightaging.org/archives/2021/02/the-damage-of-a-heart-attack-causes-the-immune-system-to-overreact/ Researchers here note a mechanism that causes T cells of the adaptive immune system to spur chronic inflammation and tissue damage following a heart attack. As the researchers note, not all inflammation is the same. Some is maladaptive, and this is particularly the case in older individuals. The aged immune...
Source: Fight Aging! - February 21, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Mandatory COVID-19 Vaccination: It ’s Worth a Shot
Morgan Hart (University of Mississippi) Mandatory COVID-19 Vaccination: It ’s Worth a Shot, SSRN: The last greatest plague in the United States was the 1918 Spanish Flu. However, in December 2019, a novel coronavirus that originated in Wuhan, China ultimately ended...
Source: HealthLawProf Blog - February 10, 2021 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs

Laws Against Discussing Pandemics, Cont ’d: Privacy
Walter OlsonIwrote last week in this space about government ’s longstanding tendency during dangerous outbreaks of contagious disease to assert control over public discussion of medical matters on the rationale of preventing the spread of misinformation. (Some members of Congressare currently trying to browbeat platforms into taking down social media posts that promote erroneous notions about vaccines.) Citing the flu pandemic of 1918 –19, I pointed out that “rather than quieting the rumor mill and the popular spread of false ideas about the virus, the tight control of information [often does] the reverse.”The...
Source: Cato-at-liberty - February 8, 2021 Category: American Health Authors: Walter Olson Source Type: blogs

COVID-19 vaccines: Safety, side effects –– and coincidence
As the pandemic rages on, it’s increasingly clear that widespread vaccination is essential to help contain it. Physical distancing, universal face coverings, and frequent handwashing are effective, but not foolproof. And of course, these measures don’t work if they are not followed. So, the rapid development of mRNA vaccines and other vaccines to prevent COVID-19 is welcome — some say miraculous — news. But while many people are scrambling to get a vaccine, others are hesitating. Start here: Are these vaccines safe and effective? It’s natural to wonder if brand new vaccines against a novel coronavirus, developed ...
Source: Harvard Health Blog - February 8, 2021 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Health Vaccines Source Type: blogs

COVID-19 vaccines: Safety, side effects — and coincidence
As the pandemic rages on, it’s increasingly clear that widespread vaccination is essential to help contain it. Physical distancing, universal face coverings, and frequent handwashing are effective, but not foolproof. And of course, these measures don’t work if they are not followed. So, the rapid development of mRNA vaccines and other vaccines to prevent COVID-19 is welcome — some say miraculous — news. But while many people are scrambling to get a vaccine, others are hesitating. Start here: Are these vaccines safe and effective? It’s natural to wonder if brand new vaccines against a novel coronavirus, developed ...
Source: Harvard Health Blog - February 8, 2021 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Health Vaccines Source Type: blogs

COVID-19 vaccines are safe for people with severe allergies
The intensive care unit nurse was worried the COVID-19 vaccine would kill her. In the past, just minutes after getting the influenza vaccine, she had hives, wheezing, and throat swelling. Her life-threatening reaction only resolved after an epinephrine injection and monitoring in the emergency room. She vowed never to get another vaccine. With the arrival […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more.
Source: Kevin, M.D. - Medical Weblog - February 3, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/charles-feng" rel="tag" > Charles Feng, MD < /a > < /span > Tags: Conditions COVID-19 coronavirus Infectious Disease Source Type: blogs

What a Year! | Pandemic Teaching & More | A Reflection | TAPP 86
Discussions that matter. In our private space, we can have the vulnerability needed for authentic, deep discussions. Discussions not limited to a sentence or two at a time.No ads. No spam. No fake news. No thoughtless re-shares. Just plain old connection with others who do what you do!Privacy. The A&P Professor community has the connectivity of Facebook and Twitter, but the security of a private membership site. None of your information can be shared outside the community, so you can share what you like without it being re-shared to the world. Like your dean, for instance. In our community, you can share your frustrati...
Source: The A and P Professor - January 27, 2021 Category: Physiology Authors: Kevin Patton Source Type: blogs

Fight Aging! Newsletter, January 25th 2021
In conclusion, our studies highlight the important role of the tyrosine degradation pathway and position TAT as a link between neuromediator production, dysfunctional mitochondria, and aging.
Source: Fight Aging! - January 24, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs