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Inexpensive Filter Isolates Circulating Tumor Cells
Researchers at Kumamoto University in Japan have designed an inexpensive and convenient filter that can isolate circulating tumor cells from as little as 1 mL of patient blood. The highly sensitive filter can successfully work in samples containing a...
Source: Medgadget - July 2, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Diagnostics Oncology Source Type: blogs

Fight Aging! Newsletter, June 21st 2021
This study showed that the leakage of this mitochondrial nucleic material may occur as a result of mitochondrial dysfunction, which may involve genetic mutations in genes encoding mitochondrial proteins or incomplete degradation of mitochondrial dsDNA in the lysosome - which is a 'degradation factory' of the cell. Upon the leakage into the cytoplasm, this undegraded dsDNA is detected by a 'foreign' DNA sensor of the cytoplasm (IFI16) which then triggers the upregulation of mRNAs encoding for inflammatory proteins." Using a PD zebrafish model (gba mutant), the researchers demonstrated that a combination of PD-like ph...
Source: Fight Aging! - June 20, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, June 7th 2021
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - June 6, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Healthcare AI, Limiting Biases, and Gold Standard Data Sets: Exclusive with Vatsal Ghiya, CEO of Shaip
Shaip is an online platform that focuses on healthcare AI data solutions and offers licensed healthcare data designed to help construct AI models. It provides text-based patient medical records and claims data, audio such as physician recordings...
Source: Medgadget - May 4, 2021 Category: Medical Devices Authors: Alice Ferng Tags: Exclusive Informatics Source Type: blogs

On Med Mal Reform, Democrats Are More Libertarian than Republicans
Michael F. CannonIn a  recentpost, I  announced the release of and provided excerpts from Cato’s latest health policy book,Medical Malpractice Litigation: How It Works, Why Tort Reform Hasn ’t Helped, by Bernard S. Black,David A. Hyman, Myungho S. Paik, William M. Sage, andCharles Silver (foreword by former Senate Majority Leader Tom Daschle).Medical Malpractice Litigationcompiles original research from states that capped damages in “med mal” cases to show that such reforms do not have the effects that physicians and other supporters claim. If anything, damage caps benefit physicians and insurance companies at th...
Source: Cato-at-liberty - May 3, 2021 Category: American Health Authors: Michael F. Cannon Source Type: blogs

3D Printed Shields Protect Guts During Radiotherapy
Researchers at Brigham and Women’s Hospital and MIT have developed 3D printed shields to protect the gastrointestinal tract from the side effects of radiotherapy. Using CT scans, the devices can be custom printed to suit each patient’s anatomy. T...
Source: Medgadget - April 27, 2021 Category: Medical Devices Authors: Conn Hastings Tags: GI Materials Radiation Oncology Radiology Source Type: blogs

Positron Emission Tomography (PET) in Cardiology
Positron emission tomography (PET) imaging is useful in assessment of myocardial perfusion and viability, atherosclerotic plaque activity as well as cardiac innervation in heart failure. PET is also useful in prosthetic valve endocarditis, endocarditis associated with cardiac implantable electronic devices (CIED), infiltrative cardiomyopathy, aortic stenosis and cardio oncology [1]. PET imaging has superior diagnostic accuracy compared to SPECT (Single Photon Emission Computed Tomography). It has improved spatial and temporal resolution and can measure regional blood flow and has less radiation. In PET, high energy gamma...
Source: Cardiophile MD - April 20, 2021 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Positron emission tomography Source Type: blogs

Accelerating the Development of Tests for Endometriosis and Cancer
NIGMS’ Small Business Technology Transfer (STTR) program works toward more effective methods for patient screening, diagnosis, and treatment. Translating lab discoveries into health care products requires large investments of time and resources. Through the STTR Regional Technology Transfer Accelerator Hubs for IDeA States program, NIGMS helps researchers interested in transitioning their discoveries and/or inventions into products. Here are the stories of three researchers working with the XLerator Hub, which funds projects in the southeastern United States and Puerto Rico. Ending Diagnostic Delays for Endomet...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - April 7, 2021 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Injury and Illness Cancer Diseases Profiles Scientific Process Source Type: blogs

After all the years of medical training, I learned how to treat ugly on my own
We first met about two years ago when she came to see me in my clinic as a new patient. I glanced through her chart and reviewed her scans and pathology reports. She had one of the worst possible kinds of lung cancers, called small cell lung cancer, that had spread to both of her […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more.
Source: Kevin, M.D. - Medical Weblog - April 6, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/farhan-s-imran" rel="tag" > Farhan S. Imran, MD < /a > < /span > Tags: Conditions Oncology/Hematology Source Type: blogs

Fight Aging! Newsletter, April 5th 2021
In this study, the research team designed a way to identify small molecules that improve the function of ABCA1 in the body while avoiding unwanted effects to the liver. The researchers honed in on a specific small molecule, CL2-57, due to its ability to stimulate ABCA1 activity with positive effects on liver and plasma triglycerides. The use of this compound showed improved glucose tolerance and insulin sensitivity, as well as reduced weight gain, among other beneficial effects. Age-Related Upregulation of Autophagy as a Possible Contribution to Bat Longevity https://www.fightaging.org/archives/2021/04/age-rela...
Source: Fight Aging! - April 4, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Joshua Greenberg on Antebellum Paper Money
George SelginAlerted by a tweet by him, I recently listened toa December 2020 C-SPAN talk, on " Paper Money in Antebellum America, " by historianJoshua Greenberg, the author ofBank Notes and Shinplasters: The Rage for Paper Money in the Early Republic.I haven ' t yet read his book. But Greenberg ' s talk is worth a listen. I was especially intrigued by his suggestion that, because they had to deal with so many different banknotes, including many of doubtful value, early Americans acquired a degree of financial savviness they sorely lack nowadays. Greenberg ' s related thesis that, by virtue of their very lack of uniformity...
Source: Cato-at-liberty - March 31, 2021 Category: American Health Authors: George Selgin Source Type: blogs

TOP 10 Dangers Of Digital Health
Thanks to the advent of digital health, the future of medicine is truly exciting. With technological advancements that democratise access to care, better treatments are accessible to people than ever before. Breakthrough research and medical developments have eradicated deadly diseases and turned others into manageable conditions. But the very developments that propel healthcare to the 21st century bring their own share of hazards to the field. From the elimination of privacy through hacked medical devices to bioterrorism, there are signs of alarming trends that few take seriously. Nevertheless, we must generate discussion...
Source: The Medical Futurist - March 30, 2021 Category: Information Technology Authors: berci.mesko Tags: Artificial Intelligence in Medicine Bioethics Biotechnology Digital Health Research Healthcare Policy Nanotechnology Security & Privacy Telemedicine & Smartphones algorithm ecg google smartwatch wearables GC1 wannacry ransomw Source Type: blogs

Top 10 Hazards Of Technology In Digital Health
Thanks to the advent of digital health, the future of medicine is truly exciting. With technological advancements that democratise access to care, better treatments are accessible to people than ever before. Breakthrough research and medical developments have eradicated deadly diseases and turned others into manageable conditions. But the very developments that propel healthcare to the 21st century bring their own share of hazards to the field. From the elimination of privacy through hacked medical devices to bioterrorism, there are signs of alarming trends that few take seriously. Nevertheless, we must generate discussion...
Source: The Medical Futurist - March 30, 2021 Category: Information Technology Authors: berci.mesko Tags: Artificial Intelligence in Medicine Bioethics Biotechnology Digital Health Research Healthcare Policy Nanotechnology Security & Privacy Telemedicine & Smartphones algorithm ecg google smartwatch wearables GC1 wannacry ransomw Source Type: blogs

Fight Aging! Newsletter, March 29th 2021
Discussion of Systemic Inflammation and its Contribution to Dementia Fisetin Reduces D-Galactose Induced Cognitive Loss in Mice Reprogramming Cancer Cells into Normal Somatic Cells Considering Longevity Medicine and the Education of Physicians Researchers Generate Thyroid Organoids Capable of Restoring Function in Mice In Search of Transcriptional Signatures of Aging A Pace of Aging Biomarker Correlates with Manifestations of Aging Targeting Tissues with Extracellular Vesicles Calorie Restriction Slows Aging of the Gut Microbiome in Mice Mitochondrial DNA Heteroplasmy in the Aging Heart Evidence for Hea...
Source: Fight Aging! - March 28, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Evaluation of the Surgical Specimen After Neoadjuvant Systemic Therapy
ConclusionPostneoadjuvant systemic therapy histopathological changes are complex, and careful systematic review of the specimen is required for accurate diagnosis and follow-up treatment. For pathological complete response to be used as an indicator of response to novel therapies, it is essential to have a standardized way in which residual disease is measured and reported. We designed the recommendations specifically for the clinical trial setting; however, they can be optionally incorporated into routine practice because, in our opinion, standardization is most effective when uniformly applied. Hopefully, such standardiz...
Source: Oncopathology - March 23, 2021 Category: Cancer & Oncology Tags: breast Breast Biopsy Procedure breast cancer Source Type: blogs