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Investigations and management of dilated cardiomyopathy
Investigations in dilated cardiomyopathy Chest X-ray PA view will assess the cardiac size in dilated cardiomyopathy and show evidence of pulmonary congestion. Sick persons may present with features of frank pulmonary edema in the form of hilar haze or bat wing pattern of pulmonary edema. Significant left ventricular dysfunction can exist without much of cardiomegaly on chest X-ray as well. ECG may show sinus tachycardia, left atrial overload and sometimes left ventricular hypertrophy. A wide QRS complex with left bundle branch block pattern may indicate potential benefit from cardiac resynchronization therapy (CRT). ECG ...
Source: Cardiophile MD - March 30, 2019 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: General Cardiology Source Type: blogs

Fight Aging! Newsletter, March 25th 2019
This study defines a new clinically relevant concept of T-cell senescence-mediated inflammatory responses in the pathophysiology of abnormal glucose homeostasis. We also found that T-cell senescence is associated with systemic inflammation and alters hepatic glucose homeostasis. The rational modulation of T-cell senescence would be a promising avenue for the treatment or prevention of diabetes. Intron Retention via Alternative Splicing as a Signature of Aging https://www.fightaging.org/archives/2019/03/intron-retention-via-alternative-splicing-as-a-signature-of-aging/ In recent years researchers have inv...
Source: Fight Aging! - March 24, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Heart of The Matter: Technology In The Future of Cardiology
Sound, rhythm, rate, structure, function – countless features of the heart are measured to keep it healthy for as long as possible. Recently, an army of digital health technologies joined the forces of traditional preventive tools in cardiology to counter stroke, heart attack, heart failure or any other cardiovascular risks. In the future, minuscule sensors, digital twins, and artificial intelligence could strengthen their ranks. Let’s see what the future of cardiology might look like! Fitness trackers, chatbots and A.I. against heart disease Let’s say 36-year-old Maria living in Sao Paulo in 2033 decides one d...
Source: The Medical Futurist - March 12, 2019 Category: Information Technology Authors: nora Tags: Artificial Intelligence in Medicine Future of Medicine Health Sensors & Trackers Portable Diagnostics cardiology cardiovascular cardiovascular diseases digital digital twin health trackers heart heart health heart rate heart soun Source Type: blogs

Some thoughts about Origin , Genesis and Mechanism of palpitation !
Not every one feels the palpitation during tachycardia / Bradycardia /VPDs , Why ? Palpitation is awareness of one’s own heart beat. It is a complex perception of sensation at cortical level (like dyspnea) . It can occur during physical and mental exertion.However , if it occurs without any physiological reasons , it becomes abnormal. It can mean an abnormally heart in terms of  heart rate , rhythm or  raise in stroke volume. The first rule of palpitation is both tachycardia and bradycardia can cause it. Tachycardic palpitation is due to valve motion and braducardic palpitation is due to both motion and increased...
Source: Dr.S.Venkatesan MD - February 24, 2019 Category: Cardiology Authors: dr s venkatesan Tags: cardinal symptom in cardiology Cardiology - Clinical Cardiology -Clinical signs Clinical cardiology Palpation mechansim of palpitation receptors for palpitation sensation of palpitation Source Type: blogs

Man Receives World ’s First Wirelessly Powered Heart Pump
Heart pumps are electromechanical devices that have all kinds of limitations placed on them. One of those is that the pumps needs quite a bit of energy to augment blood output, so a power cable protruding through the skin has always been a necessity....
Source: Medgadget - February 11, 2019 Category: Medical Devices Authors: Editors Tags: Cardiac Surgery Cardiology Critical Care Source Type: blogs

Top Smart Algorithms In Healthcare
As artificial intelligence tools have been invading more or less every area of healthcare, we made a list to keep track of the top smart algorithms aiming for better diagnostics, more sophisticated patient care or further sighted predictions of diseases. Does A.I. beat doctors? Only if you lived under a rock for the last couple of years, could you not have heard about artificial intelligence. Some might have even come across the spread and potential of A.I. in healthcare. Not only smart algorithms themselves but also the hype around A.I. has grown immensely, thus every time a new study about deep learning or machine...
Source: The Medical Futurist - February 5, 2019 Category: Information Technology Authors: nora Tags: Artificial Intelligence in Medicine AI cancer death future Health Healthcare pathology prediction Radiology technology Source Type: blogs

Fight Aging! Newsletter, January 14th 2019
In conclusion, reduction of LDL-C to less than 50 mg/dl seems safe and provides greater CV benefits compared with higher levels. Data for achieved LDL-C lower than 20-25 mg/dl is limited, although findings from the above mentioned studies are encouraging. However, further evaluation is needed for future studies and post-hoc analyses. Wary of the Beautiful Fairy Tale of Near Term Rejuvenation https://www.fightaging.org/archives/2019/01/wary-of-the-beautiful-fairy-tale-of-near-term-rejuvenation/ One might compare this interview with researcher Leonid Peshkin to last year's discussion with Vadim Gladyshev. ...
Source: Fight Aging! - January 13, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Commissioning Healthcare Policy: Hospital Readmission and Its Price Tag
By ANISH KOKA MD  The message comes in over the office slack line at 1:05 pm. There are four patients in rooms, one new, 3 patients in the waiting room. Really, not an ideal time to deal with this particular message. “Kathy the home care nurse for Mrs. C called and said her weight yesterday was 185, today it is 194, she has +4 pitting edema, heart rate 120, BP 140/70 standing, 120/64 sitting” I know Mrs. C well. She has severe COPD from smoking for 45 of the last 55 years. Every breath looks like an effort because it is. The worst part of it all is that Mrs. C just returned home from the hospital just days ago. The yo...
Source: The Health Care Blog - January 10, 2019 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Hospitals Medicare Anish Koka hospital readmissions HRRP MedPAC Source Type: blogs

More Patients Can Now Be Treated With New SAPIEN 3 Ultra Transcatheter Aortic Valve
Edwards Lifesciences received FDA approval to introduce its SAPIEN 3 Ultra transcatheter aortic heart valve in the U.S. Specifically, the device is indicated for cases of severe, symptomatic aortic stenosis identified to be at intermediate or great...
Source: Medgadget - January 2, 2019 Category: Medical Devices Authors: Editors Tags: Cardiac Surgery Cardiology Source Type: blogs

Statistical Certainty: Less is More
By ANISH KOKA MD  The day after NBC releases a story on a ‘ground-breaking’ observational study demonstrating caramel macchiatas reduce the risk of death, everyone expects physicians to be experts on the subject. The truth is that most of us hope John Mandrola has written a smart blog on the topic so we know intelligent things to tell patients and family members. A minority of physicians actually read the original study, and of those who read the study, even fewer have any real idea of the statistical ingredients used to make the study. Imagine not knowing whether the sausage you just ate contained rat droppings. At...
Source: The Health Care Blog - December 26, 2018 Category: Consumer Health News Authors: matthew holt Tags: Data Health Policy Anish Koka Brian Nosek data analysis HRRP randomized controlled trials statistics Source Type: blogs

Ignorance based cardiology : How common is “ myocardial congestion ” in cardiac failure ?
We learn from basic physiology  lessons that human body is made up of 60 % water. What about heart ? There is no reason for the heart should behave differently from rest of the body . If my  assumptions are correct when the normal heart weighs 300g  , 180g of which should be  be water. The same thing could be applicable for LV mass( * Reference requested) Is there myocardial congestion in cardiac failure ? Genesis of edema in any tissue depends on local hydrostatic pressures, tissue resistive forces, osmotic balance, and cell membrane permeability. In the myocardium individual contribution of above factors are not ...
Source: Dr.S.Venkatesan MD - November 27, 2018 Category: Cardiology Authors: dr s venkatesan Tags: cardiac failure Cardiac MRI Cardio Nephrology effect of dialysis on myocardial water content lv amss and myocardial edema myocardial edema and ckd chronic kidney failure myocardial interstitial edema myocardial water imaging water logging Source Type: blogs

Edwards SAPIEN 3 Ultra Transcatheter Valve for Severe Aortic Stenosis Cleared in Europe
Edwards Lifesciences received European CE Mark approval for its SAPIEN 3 Ultra transcatheter aortic heart valve. Indicated for valve replacement in patients with severe, symptomatic aortic stenosis, the device is available in three sizes (20 mm, 23 ...
Source: Medgadget - November 19, 2018 Category: Medical Devices Authors: Editors Tags: Cardiac Surgery Cardiology Source Type: blogs

Artificial Intelligence Diagnoses Heart Murmurs Better Than Expert Cardiologists
At the just concluded American Heart Association’s Scientific Sessions 2018 in Chicago, Eko, the makers of popular digital stethoscopes, showed off a neural network AI algorithm that is able to detect murmurs better than a group of cardiologists. ...
Source: Medgadget - November 14, 2018 Category: Medical Devices Authors: Editors Tags: Cardiology Informatics Medicine Pediatrics Source Type: blogs

HeartMate 3 Heart Pump Approved for Patients Not Eligible for Transplant
Abbott‘s HeartMate 3 left ventricular assist device (LVAD) won FDA approval to be used as a destination therapy for advanced heart failure patients who are not eligible for a transplant. Previously, the device has been indicated for patients el...
Source: Medgadget - October 23, 2018 Category: Medical Devices Authors: Editors Tags: Cardiac Surgery Cardiology Source Type: blogs