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Development of a skin cancer prevention programm for outdoor athlets
Conclusions We were able to give another hint for the relation of skin cancer development and the higher increase in outdoor sportsmen. From these data we developed in the UIPM for the athletes a "skin tumor prevention program". With this program the individual risk and the individual damage is analysed based on the cumulative UV-Dose of training and competition. Athletes, trainers and officials should be more sensitized in skin cancer prevention.
Source: British Journal of Sports Medicine - January 31, 2017 Category: Sports Medicine Authors: Nachtigall, N. Tags: Monaco abstracts Source Type: research

Efficacy of Exercise on Breast Cancer Outcomes: A Systematic Review and Meta-analysis of Preclinical Data
In conclusion, exercise performed under specific conditions benefits BT outcomes. Preclinical studies with exercise designs mimicking exercise exposure that can be used in clinical contexts are needed. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: International Journal of Sports Medicine - March 21, 2018 Category: Sports Medicine Authors: Figueira, Ana Cristina Corr êa Cortinhas, Ant ónio Soares, Jorge Pinto Leit ão, José Carlos Ferreira, Rita Pinho Duarte, Jose Alberto Tags: Review Source Type: research

microRNAs in High and Low Responders to Resistance Training in Breast Cancer Survivors
Int J Sports Med DOI: 10.1055/a-0592-7691Accounting for one in three cancer diagnoses, breast cancer is the second most commonly diagnosed cancer in women. Exercise has a well-accepted role in the multi-disciplinary approach to rehabilitating breast cancer survivors. Despite the many known benefits of resistance training on women recovering from breast cancer, the molecular mechanisms are poorly understood. MicroRNAs are small non-coding RNAs that have crucial roles in growth and development. Here, we analysed the abundance of 9 miRNAs, with known roles in muscle physiology and some linked to cancer, in serum samples from ...
Source: International Journal of Sports Medicine - April 26, 2018 Category: Sports Medicine Authors: Hagstrom, Amanda D. Denham, Joshua Tags: Genetics & Molecular Biology Source Type: research

Exercise Training-Induced Modulation in Microenvironment of Rat Mammary Neoplasms
Int J Sports Med DOI: 10.1055/a-0660-0198Despite the importance attributed to exercise training in the breast cancer (BC) continuum, the underlying mechanisms modulating tumor behavior are unknown. We evaluated the effects of long-term moderate-exercise in the development of mammary tumors, and studied the microenvironment of infiltrative lesions, the amount of connective tissue, and balance between cellular proliferation/death.Fifty Sprague-Dawley rats, randomly assigned into four groups: two control groups (sedentary and exercised) and two models of BC groups (sedentary and exercised) induced by N-methyl-N-nitrosoureia (...
Source: International Journal of Sports Medicine - August 10, 2018 Category: Sports Medicine Authors: Figueira, Ana Cristina Corr êa Figueira, Mafalda Corr êa Silva, Carina Padr ão, Ana Oliveira, Paula Alexandra Ferreira, Rita Pinho Duarte, Jose Alberto Tags: Physiology & Biochemistry Source Type: research

Synchronized Pedaling with Martial Arts Improves Quality of Life of Women with Breast Cancer
This study evaluated the effect of a new martial arts program that combined aerobic endurance and muscle strength exercises on improving upper limb function and aerobic performance of women who have undergone breast cancer surgery. Fifty-three women who had previously undergone breast cancer surgery with axillary lymph node dissection, radiotherapy and/or chemotherapy participated in the twelve-week program. Participants were randomly assigned to two groups; a study group (28 participants) in which participants carried out a synchronized pedaling with martial arts routine of 2 sessions per week, and a control group (22 par...
Source: International Journal of Sports Medicine - October 22, 2018 Category: Sports Medicine Authors: Navarro-Sanz, Ana Espejo-Reina, Alejandro Cerezo-Guzman, Maria Victoria Fernandez-Ortega, Juan F. Meza-Leiva, Hector Conejo-Tirado, Inmaculada Santiago-Sanchez, Clara Tags: Training & Testing Source Type: research

FDA Announces Recall Of Another Heart Medicine For Possible Cancer Risk
(CNN) — The US Food and Drug Administration is alerting patients of another recall of medicine used to treat high blood pressure, for a potential cancer risk due to contamination. This time, SciGen is recalling certain lots of irbesartan. The recalled lot will have “Westminster Pharmaceuticals” and “GSMS Inc.” on the label, according to the FDA list. Another heart medicine, valsartan, has also been recalled recently due to contamination. Irbesartan is an angiotensin II receptor blocker, or ARB. This is a drug that blocks a potent chemical in the blood called anigiotensin, which causes muscles ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - November 1, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Local TV Recall Source Type: news

Acute Exercise Increases the Expression of KIR2DS4 by Promoter Demethylation in NK Cells
Int J Sports Med DOI: 10.1055/a-0741-7001Positive effects of exercise on cancer prevention and progression have been proposed to be mediated by stimulating natural killer (NK) cells. Because NK cell receptors are regulated by epigenetic modifications, we investigated whether acute aerobic exercise and training change promoter DNA methylation and gene expression of the activating KIR2DS4 and the inhibiting KIR3DL1 gene. Sixteen healthy women (50–60 years) performed a graded exercise test (GXT) and were randomized into either a passive control group or an intervention group performing a four-week endurance exercise interve...
Source: International Journal of Sports Medicine - December 3, 2018 Category: Sports Medicine Authors: Schenk, Alexander Pulverer, Walter Koliamitra, Christine Bauer, Claus Juergen Ilic, Suzana Heer, Rudolf Schier, Robert Schick, Volker B öttiger, Bernd W. Gerh äuser, Clarissa Bloch, Wilhelm Zimmer, Philipp Tags: Genetics & Molecular Biology Source Type: research

Physical Exercise and Epigenetic Modifications in Skeletal Muscle
AbstractPhysical activity and sports play major roles in the overall health status of humans. It is well known that regular exercise helps to lower the risk for a broad variety of health problems, such as cardiovascular disease, type 2 diabetes, and cancer. Being physically active induces a wide variety of molecular adaptations, for example fiber type switches or other metabolic alterations, in skeletal muscle tissue. These adaptations are based on exercise-induced changes to the skeletal muscle transcriptome. Understanding their nature is crucial to improve the development of exercise-based therapeutic strategies. Recent ...
Source: Sports Medicine - February 19, 2019 Category: Sports Medicine Source Type: research

Exercise Interventions and Cardiovascular Health in Childhood Cancer: a Meta-Analysis
This study analyzed the effects of physical exercise interventions on cardiovascular endpoints in childhood cancer survivors. Relevant articles were systematically searched in PubMed, CINAHL, and Web of Science databases (since inception to 11th September 2019). We performed a meta-analysis (random effects) to determine the mean difference (expressed together with 95% confidence intervals) between pre- and post-intervention values for those cardiovascular endpoints reported in more than three studies. Twenty-seven studies (of which 16 were controlled studies) comprising 697 p...
Source: International Journal of Sports Medicine - January 13, 2020 Category: Sports Medicine Authors: Morales, Javier S. Valenzuela, Pedro L. Herrera-Olivares, Alba M. Ba ño-Rodrigo, Antonio Castillo-Garc ía, Adrián Rinc ón-Castanedo, Cecilia Mart ín-Ruiz, Asunción San-Juan, Alejandro F. Fiuza-Luces, Carmen Lucia, Alejandro Tags: Review Source Type: research

Ultraviolet Radiation Exposure, Risk, and Protection in Military and Outdoor Athletes
Overexposure to ultraviolet radiation (UVR) from the sun is associated with deleterious health effects including, but not limited to, increased risk of skin cancers. Military personnel and those who participate in outdoor exercise or sports represent two potential populations at elevated risk of negative health consequences of UVR exposure due to large amounts of time spent outdoors, often in harsh UVR environments. Despite exposure to high and/or frequent doses of UVR in recreational and tactical athletes, adequate sun-protection practices are often disregarded or not well understood by many within these at-risk populatio...
Source: Current Sports Medicine Reports - April 1, 2020 Category: Sports Medicine Tags: Environmental Conditions Source Type: research

Concurrent Exercise Interventions in Breast Cancer Survivors with Cancer-related Fatigue
This study compared the effects of two supervised concurrent training interventions in breast cancer survivors with cancer-related fatigue at baseline. Twenty-three female breast cancer survivors (50±8 years) were randomized to a high- (n=13) or a moderate-intensity (n=10) training program. Both interventions lasted 16 weeks and included the same resistance exercises, but the aerobic component was supervised and more intense in the former (i.e., rating of perceived exertion of 7–8 vs. 6 on a 1–10 scale for the high and moderate-intensity intervention, respectively). The primary ...
Source: International Journal of Sports Medicine - June 28, 2020 Category: Sports Medicine Authors: Pagola, Itiziar Morales, Javier S. Alejo, Lidia B. Barcelo, Olga Montil, Marta Oliv án, Jesús Álvarez-Bustos, Alejandro Cantos, Blanca Maximiano, Constanza Hidalgo, Francisco Valenzuela, Pedro L. Fiuza-Luces, Carmen Lucia, Alejandro Ruiz-Casado, Ana Tags: Clinical Sciences Source Type: research

Resistance Exercise Modulates Kynurenine Pathway in Pancreatic Cancer Patients
Int J Sports Med DOI: 10.1055/a-1186-1009The aim of this study was to investigate the impact of Supervised and Home-based resistance exercise on the Kynurenine pathway in patients with pancreatic cancer who underwent surgery and chemotherapy. In the SUPPORT study, adult pancreatic cancer patients were randomized to intervention programs of 6-month (1) a Supervised moderate-to-high-intensity progressive resistance training or (2) unsupervised Home-based resistance training, or (3) to a standard care patient Control group. Serum levels of kynurenine, tryptophan and IL-6 were assessed for 32...
Source: International Journal of Sports Medicine - July 23, 2020 Category: Sports Medicine Authors: Pal, Anasua Zimmer, Philipp Clauss, Dorothea Schmidt, Martina E. Ulrich, Cornelia M. Wiskemann, Joachim Steindorf, Karen Tags: Physiology & Biochemistry Source Type: research

Reply: Letter to the Editor: Exercise Interventions and Cardiovascular Health in Childhood Cancer: A Meta-Analysis
Int J Sports Med 2020; 41: 629-629 DOI: 10.1055/a-1195-7025Dear EditorWe sincerely appreciate the nice comments by Drs. P.V. da Costa Ghignatti and R. Pereira de Lima 1 concerning our recent meta-analysis assessing the effects of physical exercise interventions on cardiovascular endpoints in childhood cancer survivors 2. They are quite right to remain that even non-significant improvements in cardiorespiratory fitness (CRF) might be clinically relevant. Indeed, we still do not know if CRF increments of a theoretically low magnitude (i. e., <1 metabolic equivalent) might have a progno...
Source: International Journal of Sports Medicine - August 3, 2020 Category: Sports Medicine Authors: Morales, Javier S. Valenzuela, Pedro L. Herrera-Olivares, Alba M. Ba ño-Rodrigo, Antonio Castillo-Garc ía, Adrián Rinc ón-Castanedo, Cecilia Mart ín-Ruiz, Asunción San Juan, Alejandro F. Fiuza-Luces, Carmen Alejandro, Lucia Tags: Letter to the Editor Source Type: research

Correction: Reply: Letter to the Editor: Exercise Interventions and Cardiovascular Health in Childhood Cancer: A Meta-Analysis
Int J Sports Med DOI: 10.1055/a-1240-2907 © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Full text
Source: International Journal of Sports Medicine - September 2, 2020 Category: Sports Medicine Authors: Morales, Javier S. Valenzuela, Pedro L. Herrera-Olivares, Alba M. Ba ño-Rodrigo, Antonio Castillo-Garc ía, Adrián Rinc ón-Castanedo, Cecilia Mart ín-Ruiz, Asunción San Juan, Alejandro F. Fiuza-Luces, Carmen Lucia, Alejandro Tags: Erratum Source Type: research

Role of Regular Physical Exercise in Tumor Vasculature: Favorable Modulator of Tumor Milieu
Int J Sports Med DOI: 10.1055/a-1308-3476The tumor vessel network has been investigated as a precursor of an inhospitable tumor microenvironment, including its repercussions in tumor perfusion, oxygenation, interstitial fluid pressure, pH, and immune response. Dysfunctional tumor vasculature leads to the extravasation of blood to the interstitial space, hindering proper perfusion and causing interstitial hypertension. Consequently, the inadequate delivery of oxygen and clearance of by-products of metabolism promote the development of intratumoral hypoxia and acidification, hampering the action of immune cells and resulting...
Source: International Journal of Sports Medicine - December 11, 2020 Category: Sports Medicine Authors: Esteves, M ário Monteiro, Mariana P. Duarte, Jose Alberto Tags: Review Source Type: research