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Cancer: Carcinoma
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Vascular and Neural Invasion in Oral Squamous Cell Carcinoma: A Study in an Iranian Population
CONCLUSION: The relation between neural and vascular invasion in OSCC with tumor's location was statistically significant. Lip and tongue carcinoma had shown more neurovascular invasion without relation to gender, age, and cell differentiation.PMID:37200766 | PMC:PMC10186046 | DOI:10.4103/abr.abr_220_21
Source: Adv Data - May 18, 2023 Category: Epidemiology Authors: Nakisa Torabinia Gholamreza Jahanshahi Vahid Eslami Forooz Keshani Source Type: research
In vitro study of normoxic epidermal growth factor receptor–induced hypoxia‐inducible factor‐1‐alpha, vascular endothelial growth factor, and BNIP3 expression in head and neck squamous cell carcinoma cell lines: Implications for anti–epidermal growth factor receptor therapy
ConclusionThe search for molecular predictors of sensitivity to gefitinib in HNSCC should be extended to the activation status of EGFR‐downstream pathways, phosphorylated protein kinase B, pMAPK, and HIF‐1α. © 2014 Wiley Periodicals, Inc. Head Neck, 2014
Source: Head and Neck - July 7, 2014 Category: ENT & OMF Authors: Pablo Secades, Inés Saenz Santa‐María, Anna Merlo, Carlos Suarez, María‐Dolores Chiara Tags: Original Article Source Type: research
NCAPG is a prognostic biomarker associated with vascular invasion in hepatocellular carcinoma
CONCLUSIONS: NCAPG upregulation is associated with poor prognosis in hepatocellular carcinoma patients with vascular invasion.PMID:34919223 | DOI:10.26355/eurrev_202112_27417
Source: Pharmacological Reviews - December 17, 2021 Category: Drugs & Pharmacology Authors: Z-Y Guo Z-T Zhu Source Type: research
< em > TFEB < /em > -translocated and -amplified renal cell carcinoma with < em > VEGFA < /em > co-amplification: A case of long-term control by multimodal therapy including a vascular endothelial growth factor-receptor inhibitor
CONCLUSION: A good long-term response to anti-vascular endothelial growth factor drug therapy may be due to VEGFA amplification and subsequent vascular endothelial growth factor overexpression.PMID:37144078 | PMC:PMC10151203 | DOI:10.1002/iju5.12575
Source: Cancer Control - May 5, 2023 Category: Cancer & Oncology Authors: Hajime Takamori Akiko Miyagi Maeshima Ikuma Kato Masaya Baba Eijiro Nakamura Yoshiyuki Matsui Source Type: research
Matrix metalloproteinase 12 (MMP12) as an adverse prognostic biomarker of vascular invasion in hepatic cell carcinoma
CONCLUSIONS: Upregulation of MMP12 was associated with poor prognosis and vascular invasion in HCC. These data suggest that MMP12 may have potential as a therapeutic target and biomarker in HCC.PMID:35442508 | DOI:10.26355/eurrev_202204_28454
Source: Pharmacological Reviews - April 20, 2022 Category: Drugs & Pharmacology Authors: Z-Y Guo L-P Jiang Source Type: research
Regulatory tumor-infiltrating lymphocytes prevail in endometrial tumors with low vascular survival ability
CONCLUSIONS: Low vascular survival ability relates to high accumulation of regulatory T-cells in inner tumor areas of endometrial carcinomas. The current data hypothesizes meaningful interactions between vascular survival, microenvironmental conditions, and immunosuppression in endometrial cancer.PMID:33725493 | DOI:10.1016/j.imbio.2021.152078
Source: Immunobiology - March 16, 2021 Category: Allergy & Immunology Authors: Alexandra Giatromanolaki Maria Kouroupi Emmanuel N Kontomanolis Michael I Koukourakis Source Type: research
Sphingosine 1-phosphate and its regulatory role in vascular endothelial cells
We presently review the levels of S1P in those vascular and vascular-related diseases. Plasma S1P levels were reduced in various inflammation-related diseases such as atherosclerosis and sepsis, but were increased in other diseases including type 2 diabetes, neurodegeneration, cerebrovascular damages such as acute ischemic stroke, Alzheimer's disease, vascular dementia, angina, heart failure, idiopathic pulmonary fibrosis, community-acquired pneumonia, and hepatocellular carcinoma. Then, we highlighted the molecular mechanism by which S1P regulated EC biology including vascular development and angiogenesis, inflammation, p...
Source: Atherosclerosis - February 4, 2022 Category: Cardiology Authors: Yan Qiu Junyi Shen Wenli Jiang Yi Yang Xiaoheng Liu Ye Zeng Source Type: research
