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Total 34443 results found since Jan 2013.

Predictive factors of pathological vascular invasion in hepatocellular carcinoma within 3 cm and 3 nodules without radiological vascular invasion
ConclusionAFP > 100 ng/ml and PIVKA‐II > 100 mAU/ml can predict pathological vascular invasion in patients with HCCs within 3 cm and 3 nodules without radiological vascular invasion. In treating such cases, a hepatic resection rather than a local ablation therapy is recommended. This article is protected by copyright. All rights reserved.
Source: Hepatology Research - December 15, 2015 Category: Internal Medicine Authors: Toshiro Masuda, Toru Beppu, Hirohisa Okabe, Hidetoshi Nitta, Katsunori Imai, Hiromitsu Hayashi, Akira Chikamoto, Kenichiro Yamamoto, Satoshi Ikeshima, Masafumi Kuramoto, Shinya Shimada, Hideo Baba Tags: Original Article Source Type: research

Predictive factors of pathological vascular invasion in hepatocellular carcinoma within 3 cm and three nodules without radiological vascular invasion
ConclusionAFP of more than 100 ng/mL and PIVKA‐II of more than 100 mAU/mL can predict pathological vascular invasion in patients with HCC within 3 cm and three nodules without radiological vascular invasion. In treating such cases, hepatic resection rather than local ablation therapy is recommended.
Source: Hepatology Research - February 4, 2016 Category: Internal Medicine Authors: Toshiro Masuda, Toru Beppu, Hirohisa Okabe, Hidetoshi Nitta, Katsunori Imai, Hiromitsu Hayashi, Akira Chikamoto, Kenichiro Yamamoto, Satoshi Ikeshima, Masafumi Kuramoto, Shinya Shimada, Hideo Baba Tags: Original Article Source Type: research

Predictive factors of pathological vascular invasion in hepatocellular carcinoma within 3  cm and three nodules without radiological vascular invasion
ConclusionAFP of more than 100 ng/mL and PIVKA‐II of more than 100 mAU/mL can predict pathological vascular invasion in patients with HCC within 3 cm and three nodules without radiological vascular invasion. In treating such cases, hepatic resection rather than local ablation therapy is recommended.
Source: Hepatology Research - February 3, 2016 Category: Internal Medicine Authors: Toshiro Masuda, Toru Beppu, Hirohisa Okabe, Hidetoshi Nitta, Katsunori Imai, Hiromitsu Hayashi, Akira Chikamoto, Kenichiro Yamamoto, Satoshi Ikeshima, Masafumi Kuramoto, Shinya Shimada, Hideo Baba Tags: Original Article Source Type: research

SET8 ，a novel regulator to ameliorate vascular calcification via activating PI3K/Akt mediated anti-apoptotic effects
Biochem Cell Biol. 2021 Nov 30. doi: 10.1139/bcb-2021-0322. Online ahead of print.ABSTRACTPrevious studies have showed that the apoptosis of vascular smooth muscle cells (VSMCs) underlies the mechanism of pathological calcifications in patients with chronic kidney disease (CKD). SET domain-containing protein 8 (SET8), as an efficient protein has been reported to modulate cell apoptosis in hepatocellular carcinoma cell, esophageal squamous cell and neuronal cell through regulating pathological processes, such as cell-cycle progression and transcription regulation. However, whether SET8 is involved in high phosphorus induced...
Source: Biochemistry and Cell Biology - November 30, 2021 Category: Biochemistry Authors: Ya Ling Bai Mei Juan Cheng Jing Jing Jin Hui Ran Zhang Lei He Wei Zhou Sheng Lei Zhang Jin Sheng Xu Source Type: research

Study on the material basis of Dahuang Zhechong Pill of anti-hepatoma effect by promoting vascular normalization
Biomed Chromatogr. 2021 Dec 29:e5305. doi: 10.1002/bmc.5305. Online ahead of print.ABSTRACTDahuang Zhechong Pill (DHZCP) is a traditional Chinese medicine prescription to treat many diseases especially Chronic Liver Diseases (CLD) accompanied by promoting vascular normalization. In this work, UPLC-Q/TOF-MS/MS analysis was applied to identify the chemical components absorbed in the blood. HIF-1α, VEGF, Ang2 and Tie2 related to vascular normalization were detected to determine the dynamic changes of pharmacodynamics indicators. Then, the spectrum-effect relationship analysis between UHPLC fingerprint and pharmacodynamics in...
Source: Biomedical Chromatography : BMC - December 30, 2021 Category: Biomedical Science Authors: Honglin Chen Furong Yang Chuankui Fu Zimeng Zhang Kejia Xu Shengfeng Lu Zhipeng Chen Li Wu Weidong Li Source Type: research

Vascular endothelial growth factor A is a potential prognostic biomarker and correlates with immune cell infiltration in hepatocellular carcinoma
J Cell Mol Med. 2023 Feb 2. doi: 10.1111/jcmm.17678. Online ahead of print.ABSTRACTHepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related deaths among cancer patients. Vascular endothelial growth factor A (VEGFA) is involved in regulating biological processes, such as angiogenesis and vascular permeability, and is very closely related to the pathogenesis of various tumours, especially vascular-rich, solid tumours. Clinical data of patients with HCC and other tumours were analysed through public databases, such as the TCGA database, Gene Expression Omnibus database, Human Protein Atlas database, STRING...
Source: J Cell Mol Med - February 2, 2023 Category: Molecular Biology Authors: Yuchen Qi Yinghui Song Mengting Cai Jianwen Li Zhangtao Yu Yuhang Li Junkai Huang Yu Jiang Chuang Peng Bo Jiang Sulai Liu Source Type: research

Vascular complications related to image-guided percutaneous thermal ablation of hepatic tumors
Diagn Interv Radiol. 2023 Mar 29;29(2):318-325. doi: 10.5152/dir.2022.21809. Epub 2023 Mar 13.ABSTRACTPercutaneous thermal ablation of hepatic tumors is accepted as a safe, reliable, and cost-effective therapeutic option for treating hepatocellular carcinoma and hepatic metastases. However, operators should be familiar with the myriad of vascular and non-vascular complications that can occur post-ablation and that are described in the literature. This review will focus on the various vascular complications related to percutaneous thermal ablation of hepatic tumors and discuss strategies to avoid and manage these complicati...
Source: Diagnostic and Interventional Radiology : The Turkish Society of Radiology - March 29, 2023 Category: Radiology Authors: Sonam Tashi Apoorva Gogna Sum Leong Nanda Venkatanarasimha Sivanathan Chandramohan Source Type: research

Evaluation of the Vascular Architecture of Focal Liver Lesions Using Micro Flow Imaging
Conclusions— Micro flow imaging permitted detailed delineation of the vascular architecture of focal liver lesions. Hepatocellular carcinoma, metastasis, focal nodular hyperplasia, and hemangioma showed characteristic vascular architecture.
Source: Journal of Ultrasound in Medicine - June 26, 2013 Category: Radiology Authors: Yang, H., Liu, G.-J., Lu, M.-D., Xu, H.-X., Xie, X.-Y. Tags: Original Research Source Type: research