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Total 60670 results found since Jan 2013.

Visual search in breast imaging: A review.
Abstract Breast cancer is the most common cancer among females worldwide and large volumes of breast images are produced and interpreted annually. As long as radiologists interpret these images, the diagnostic accuracy will be limited by human factors and both false-positive and false-negative errors might occur. By understanding visual search in breast images, we may be able to identify causes of diagnostic errors, find ways to reduce them, and also provide a better education to radiology residents. Many visual search studies in breast radiology have been devoted to mammography. These studies showed that 70% of m...
Source: The British Journal of Radiology - July 8, 2019 Category: Radiology Authors: Gandomkar Z, Mello-Thoms C Tags: Br J Radiol Source Type: research

Deep Learning and Machine Learning with Grid Search to Predict Later Occurrence of Breast Cancer Metastasis Using Clinical Data
CONCLUSIONS: Our results show that deep learning with grid search overall performs at least as well as other machine learning methods when using non-image clinical data. It is interesting to note that some of the other machine learning methods, such as XGB, RF, and SVM, are very strong competitors of DFNN when incorporating grid search. It is also worth noting that the computation time required to do grid search with DFNN is much more than that required to do grid search with the other nine machine learning methods.PMID:36233640 | DOI:10.3390/jcm11195772
Source: Clinical Breast Cancer - October 14, 2022 Category: Cancer & Oncology Authors: Xia Jiang Chuhan Xu Source Type: research

Platinum-based chemotherapy for early triple-negative breast cancer
CONCLUSIONS: Platinum-based chemotherapy using carboplatin in the adjuvant or neoadjuvant setting improves long-term outcomes of DFS and OS in early TNBC, with no evidence of differences by subgroup. This was at the cost of more frequent chemotherapy delays and dose reductions, and greater haematological toxicity, though serious adverse events including neuropathy, febrile neutropenia or treatment-related death were not increased. These findings support the use of platinum-based chemotherapy for people with early TNBC. The optimal dose and regimen are not defined by this analysis, but there is a suggestion that similar rel...
Source: Cochrane Database of Systematic Reviews - September 8, 2023 Category: General Medicine Authors: Sofia Re Mason Melina L Willson Sam J Egger Jane Beith Rachel F Dear Annabel Goodwin Source Type: research

Readability Analysis of Online Breast Cancer Surgery Patient Education Materials from National Cancer Institute-Designated Cancer Centers Compared with Top Internet Search Results
CONCLUSIONS: Patient education materials on breast cancer from both NCI-DCC and top Internet search results were written several reading grade levels higher than the NIH recommendation. Materials should be revised to enhance patient comprehension of breast cancer surgical treatment and guide patients in this important decision-making process to ultimately improve health outcomes.PMID:37707665 | DOI:10.1245/s10434-023-14279-5
Source: Ann Oncol - September 14, 2023 Category: Cancer & Oncology Authors: Anna Rauzi Lauren E Powell McKenzie White Saranya Prathibha Jane Yuet Ching Hui Source Type: research

Feasibility of Feature-based Indexing, Clustering, and Search of Clinical Trials. A Case Study of Breast Cancer Trials from ClinicalTrials.gov.
Conclusions: It is feasible to develop feature-based indexing and clustering methods for clinical trials to identify trials with similar target populations and to improve trial search efficiency. PMID: 23666475 [PubMed - as supplied by publisher]
Source: Methods of Information in Medicine - May 13, 2013 Category: Information Technology Authors: Boland MR, Miotto R, Gao J, Weng C Tags: Methods Inf Med Source Type: research

The Effect of Patient Narratives on Information Search in a Web-Based Breast Cancer Decision Aid: An Eye-Tracking Study
Conclusions: The observed increase in fixation duration with video patient testimonials is consistent with the idea that the vividness of the video content could cause greater elaboration of the message, thereby encouraging greater information search. Conversely, because reading requires more effortful processing than watching, reading patient narratives may have decreased participant motivation to engage in more reading in the remaining sections of the Web decision aid. These findings suggest that the format of patient stories may be equally as important as their content in determining their effect on decision making. Mor...
Source: Journal of Medical Internet Research - December 17, 2013 Category: Journals (General) Authors: Victoria A ShafferJustin OwensBrian J Zikmund-Fisher Source Type: research

Relationship Between State-Level Google Online Search Volume and Cancer Incidence in the United States: Retrospective Study
Conclusions: Cancer incidence is correlated with online search volume at the state level. Search patterns were temporally associated with cancer awareness months and celebrity announcements. Online searches reflect public awareness. Advancing understanding of online search patterns could augment traditional epidemiologic surveillance, provide opportunities for targeted patient engagement, and allow public information campaigns to be evaluated in ways previously unable to be measured.
Source: Journal of Medical Internet Research - January 8, 2018 Category: General Medicine Authors: Charles A. Phillips Allison Barz Leahy Yimei Li Marilyn M. Schapira L. Charles Bailey Raina M. Merchant Source Type: research

Platinum-based chemotherapy for early triple-negative breast cancer
CONCLUSIONS: Platinum-based chemotherapy using carboplatin in the adjuvant or neoadjuvant setting improves long-term outcomes of DFS and OS in early TNBC, with no evidence of differences by subgroup. This was at the cost of more frequent chemotherapy delays and dose reductions, and greater haematological toxicity, though serious adverse events including neuropathy, febrile neutropenia or treatment-related death were not increased. These findings support the use of platinum-based chemotherapy for people with early TNBC. The optimal dose and regimen are not defined by this analysis, but there is a suggestion that similar rel...
Source: Cancer Control - September 8, 2023 Category: Cancer & Oncology Authors: Sofia Re Mason Melina L Willson Sam J Egger Jane Beith Rachel F Dear Annabel Goodwin Source Type: research

Hypothesis driven single nucleotide polymorphism search (HyDn-SNP-S).
Abstract The advent of complete-genome genotyping across phenotype cohorts has provided a rich source of information for bioinformaticians. However the search for SNPs from this data is generally performed on a study-by-study case without any specific hypothesis of the location for SNPs that are predictive for the phenotype. We have designed a method whereby very large SNP lists (several gigabytes in size), combining several genotyping studies at once, can be sorted and traced back to their ultimate consequence in protein structure. Given a working hypothesis, researchers are able to easily search whole genome gen...
Source: DNA Repair - July 4, 2013 Category: Genetics & Stem Cells Authors: Swett RJ, Elias A, Miller JA, Dyson GE, Andrés Cisneros G Tags: DNA Repair (Amst) Source Type: research