Filtered By:
Cancer: Squamous Cell Carcinoma
This page shows you your search results in order of relevance. This is page number 3.
Order by Relevance | Date
Total 7262 results found since Jan 2013.
Genomic profiling of esophageal squamous cell carcinoma (ESCC) − basis for precision medicine
Conclusion This study revealed the genetic profiles of ESCC, which may provide a foundation for the development of novel targeted therapy and precision medicine.
Source: Pathology Research and Practice - February 28, 2017 Category: Pathology Source Type: research
Investigation of pathology malpractice claims in China from 2002-2015
Conclusion Our data are in agreement with other findings regarding the most frequent medical malpractice allegations related to pathology. Addressing the issues at the root of these claims would lead to a decline in the number of medical errors. Quality assurance programs and good pathologist-clinician communication may decrease the risk of litigation.
Source: Journal of Forensic and Legal Medicine - April 16, 2017 Category: Forensic Medicine Source Type: research
Genomic profiling of esophageal squamous cell carcinoma (ESCC) —Basis for precision medicine
Conclusion This study revealed the genetic profiles of ESCC, which may provide a foundation for the development of novel targeted therapy and precision medicine.
Source: Pathology Research and Practice - June 10, 2017 Category: Pathology Source Type: research
DNA polymeric films as a support for cell growth as a new material for regenerative medicine: compatibility and applicability.
In this study, we evaluated the growth behavior of oral squamous cell carcinoma (OSCC) cells on DNA-PFs. The morphological, biochemical, and cytometric features of OSCC cell adhesion on DNA-PFs were also assessed. An initial, temporary alteration in cell morphology was observed at early time points owing to the inhibition of cell attachment to the film, which then returned to a normal morphological state at later time points. MTT and resazurin assays showed a moderate reduction in cell viability related to increased DNA concentration in the DNA-PFs. Flow cytometry studies showed low cytotoxicity of DNA-PFs, with cell viabi...
Source: Experimental Cell Research - September 21, 2017 Category: Cytology Authors: Jayme CC, de Paula LB, Rezende N, Calori IR, Franchi LP, Tedesco AC Tags: Exp Cell Res Source Type: research
The effects of Emblica officinalis and Tinospora cordifolia herbal treatment on the prognosis of squamous cell carcinoma of the buccal mucosa and tongue
Publication date: Available online 29 September 2017 Source:Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology Author(s): D.K. Dias, N.A. de S. Amaratunga, B. Perera, L.P.A. Karunathilake, C. Atukorala Objective The fruit of Emblica officinalis (Eo) and Tinospora cordifolia (Tc) has been widely consumed as a folk medicine in Southeast Asia due to its nutritional and pharmacological effects. Number of laboratory research showed these herbs have an inhibitory effect on cancer cells. A randomized double blind prospective clinical trial was conducted during 2005–2009 to determine whether a herbal preparation...
Source: Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology - September 30, 2017 Category: ENT & OMF Source Type: research
A highly integrated precision nanomedicine strategy to target esophageal squamous cell Cancer molecularly and physically
This study utilized a highly integrated precision nano- medicine strategy that combines the identification of cancer molecular target from human patients, precision drug delivery and effective combination therapy for the development of better ESCC treatment. Graphical abstract
Source: Nanomedicine: Nanotechnology, Biology and Medicine - July 3, 2018 Category: Nanotechnology Source Type: research
Considering the downregulation of Tpm1.6 and Tpm1.7 in squamous cell carcinoma of esophagus as a potent biomarker
Personalized Medicine, Ahead of Print.
Source: Future Medicine: Personalized Medicine - September 27, 2018 Category: Genetics & Stem Cells Authors: Maryam Zare Faranak Hadi Mohammad Reza Alivand Source Type: research
Topical immunotherapy keeps skin cancer risk at bay
(Washington University School of Medicine) A combination of two topical creams already shown to clear precancerous skin lesions from sun-damaged skin also lowers the risk that patients will later develop squamous cell carcinoma of the skin. The study, from Washington University School of Medicine in St. Louis, Massachusetts General Hospital, and Harvard Medical School, appears March 21 in JCI Insight.
Source: EurekAlert! - Medicine and Health - March 21, 2019 Category: International Medicine & Public Health Source Type: news
Misuse of traditional Chinese medicine may be a risk factor to tumorigenesis and progression of head and neck carcinoma in China: a hypothesis based on a case series.
CONCLUSION: Due to its unclear components, potential toxicities, misuse, and over-application, TCM might contribute to tumorigenesis and progression of head neck carcinoma. We seek effective approaches to ensure the safe use of TCM.
PMID: 31424693 [PubMed - in process]
Source: Journal of B.U.ON. - August 20, 2019 Category: Cancer & Oncology Tags: J BUON Source Type: research
Signaling Complexity Measured by Shannon Entropy and Its Application in Personalized Medicine
In this report, we explored data from human RNA-seq and protein–protein interaction (PPI) networks using bioinformatics to investigate the relationship between tumor entropy and aggressiveness. To compare PPI subnetworks of different sizes, we calculated the Shannon entropy associated with vertex connections of differentially expressed genes comparing tumor samples with their paired control tissues. We found that the inhibition of up-regulated connectivity hubs led to a higher reduction of subnetwork entropy compared to that obtained with the inhibition of targets selected at random. Furthermore, these hubs were describe...
Source: Frontiers in Genetics - October 20, 2019 Category: Genetics & Stem Cells Source Type: research
Targeted molecular imaging of head and neck squamous cell carcinoma: a window into precision medicine.
Abstract
Tumor biomarkers play important roles in tumor growth, invasion, and metastasis. Imaging of specific biomarkers will help to understand different biological activities, thereby achieving precise medicine for each head and neck squamous cell carcinoma (HNSCC) patient. Here, we describe various molecular targets and molecular imaging modalities for HNSCC imaging. An extensive search was undertaken in the PubMed database with the keywords including "HNSCC," "molecular imaging," "biomarker," and "multimodal imaging." Imaging targets in HNSCC consist of the epidermal growth factor receptor, cluster of differen...
Source: Chinese Medical Journal - May 10, 2020 Category: General Medicine Authors: Wu J, Yuan Y, Tao XF Tags: Chin Med J (Engl) Source Type: research
Value of Precision Medicine in Advanced Non-Small Cell Lung Cancer: Real-World Outcomes Associated With the Use of Companion Diagnostics.
CONCLUSION: Patients with non-Sq aNSCLC who had CDx testing had a greater survival benefit than those without, supporting broader use of CDx testing in routine clinical practice to identify patients more likely to benefit from precision medicine.
IMPLICATIONS FOR PRACTICE: Companion diagnostic (CDx) testing coupled with biomarker-driven treatment offers a greater survival benefit for patients with advanced non-small cell lung cancer (aNSCLC). In this study, patients with non-squamous aNSCLC from Flatiron Health-a large, real-world oncology database-with CDx testing had a reduced mortality risk and lived longer than pa...
Source: The Oncologist - July 5, 2020 Category: Cancer & Oncology Authors: John A, Shah RA, Wong WB, Schneider CE, Alexander M Tags: Oncologist Source Type: research
Network Pharmacology-Based Analysis of the Effects of Corydalis decumbens (Thunb.) Pers. in Non-Small Cell Lung Cancer
This study aimed to investigate the potential therapeutic targets and pharmacological mechanisms of action of the traditional Chinese medicine Corydalis decumbens (Thunb.) Pers. in NSCLC based on network pharmacology and bioinformatics. The overlapping genes between Corydalis decumbens (Thunb.) Pers. and NSCLCs were screened using Venn analysis. Cytoscape 3.7.1 software was used to analyze the overlapping target protein-protein interaction (PPI) network. Gene ontology and pathway enrichment analysis using the Kyoto Encyclopedia of Genes and Genomics database were performed to exploring biological functions of the overlappi...
Source: Evidence-based Complementary and Alternative Medicine - September 9, 2021 Category: Complementary Medicine Authors: Jun Liu Zhibo He Shan Li Wenan Huang Zhongjie Ren Source Type: research
The importance of enhancer methylation for epigenetic regulation of tumorigenesis in squamous lung cancer
Experimental & Molecular Medicine, Published online: 05 January 2022; doi:10.1038/s12276-021-00718-4The aberrant methylation of specific regions of DNA may play a significant role in regulating tumorigenesis in lung squamous cell carcinoma (LUSC). LUSC development is linked to smoking, but epigenetic regulation mechanisms in LUSC are unclear. Hye Ryun Kim at Yonsei University College of Medicine and Insusk Lee at Yonsei University in Seoul, Korea, and co-workers compared DNA methylation patterns in samples of tumor and adjacent normal tissues from 37 LUSC patients. They paid particular attention to differentially methy...
Source: Experimental and Molecular Medicine - January 5, 2022 Category: Molecular Biology Authors: Jae-Won Cho Hyo Sup Shim Chang Young Lee Seong Yong Park Min Hee Hong Insuk Lee Hye Ryun Kim Source Type: research
Retracted Long non ‑coding RNA < em > PRNCR1 < /em > exerts oncogenic effects in tongue squamous cell carcinoma < em > in vitro < /em > and < em > in vivo < /em > by sponging microRNA ‑944 and thereby increasing HOXB5 expression
Int J Mol Med. 2022 Oct;50(4):127. doi: 10.3892/ijmm.2022.5183. Epub 2022 Aug 25.ABSTRACTFollowing the publication of this paper, it was drawn to the Editors' attention by a concerned reader that certain of the flow cytometric data shown in Fig. 4I were strikingly similar to data appearing in different form in another article by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere prior to its submission to International Journal of Molecular Medicine, the Editor has decided that this paper should be retracted from the Journal. The authors were asked for an...
Source: International Journal of Molecular Medicine - August 25, 2022 Category: Molecular Biology Authors: Cong Lin Yanan Zou Ruijing Li Daofeng Liu Source Type: research
