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Total 22467 results found since Jan 2013.

Neuro-Ophthalmic Manifestations of Intracranial Malignancies
Conclusion: Intracranial malignancies can present with neuro-ophthalmic symptoms or signs depending on topographical localization. Specific neuro-ophthalmic presentations are associated with different malignant intracranial tumors. Clinicians should be aware of the common malignant intracranial tumors and their associated clinical presentations in neuro-ophthalmology.
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Trainees' Corner Source Type: research

Optimization Of High-Grade Glioma Resection Using 5-Ala Fluorescence-Guided Surgery: Literature Review And Practical Recommendations From The Neuro-Oncology Club Of The French Society Of Neurosurgery.
CONCLUSION: Although 5-ALA-FGS improves glioma treatment, it still has some limitations. Future technical developments will improve sensitivity. PMID: 31125558 [PubMed - as supplied by publisher]
Source: Neuro-Chirurgie - May 20, 2019 Category: Neurosurgery Authors: Picart T, Berhouma M, Dumot C, Pallud J, Metellus P, Armoiry X, Guyotat J Tags: Neurochirurgie Source Type: research

Impact of Covid-19 Pandemic on Neuro-Oncology Multidisciplinary Tumor Board in the Pre-Vaccine Era: the Normandy experience
CONCLUSION: The pre-vaccination era of the COVID19 pandemic did not impact the activity of neuro-oncology multidisciplinary tumor board in the Normandy region. The possible consequences in terms of public health (excess mortality) due to this tumor location should now be investigated.PMID:36870566 | PMC:PMC9979624 | DOI:10.1016/j.neuchi.2023.101429
Source: Neuro-Chirurgie - March 4, 2023 Category: Neurosurgery Authors: Marine Lacaud Arthur Leclerc Florent Marguet Maxime Faisant Paul Lesueur Houria El Ouazzani Fr édéric Di Fiore Chantal Hanzen Evelyne Emery Olivier Langlois Maxime Fontanilles Source Type: research

Do animal models of brain tumors replicate human peritumoral edema? a systematic literature search
ConclusionNo animal model currently exists that enable the investigation of novel candidates for the treatment of peritumoral brain edema. With current interest in alternative treatments for peritumoral brain edema, there is an unmet need for clinically relevant animal models.
Source: Journal of Neuro-Oncology - February 9, 2023 Category: Cancer & Oncology Source Type: research

Ni-47 * gliomatosis meningi and gliomatosis cerebri: kissing cousins? case report and review of the literature
We report the case of a 63 year-old man who first presented with a grand mal seizure followed by progressive neurological decline, hydrocephalus, and spinal radiculopathy. He had an initial tentative diagnosis of neurosarcoidoisis radiographically. He went on to have progressive leptomeningeal enhancement on MRI involving the brain and the spinal cord with a negative initial temporal lobe biopsy followed by a subsequent biopsy of the leptomeninges, which revealed Leptomeningeal Gliomatosis. He continued to decline clinically and died 9 months after symptom onset despite treatment with craniospinal radiation therapy and che...
Source: Neuro-Oncology - November 3, 2014 Category: Cancer & Oncology Authors: Khouri, J., Taylor, L. Tags: NEURO-IMAGING (CLINICAL AND/OR LABORATORY RESEARCH) Source Type: research

Stmc-23. ethical perspectives on unproven stem cell transplants in neuro-oncological disease
The application of stem cell transplants in clinical practice has become increasingly common, and many neurological diseases, including malignant brain tumors, are being targeted for intervention with stem cell transplants. The transplant procedures currently being carried out are frequently unregulated and may endanger patients. In most cases, patients undergoing such operations are not included in a clinical trial, and often do not provide genuinely informed consent. We performed a systematic search of the PubMed database to identify articles that referenced the use of the ethics of stem cell transplants in the treatment...
Source: Neuro-Oncology - November 6, 2016 Category: Cancer & Oncology Authors: Cote, D., Smith, T., Bredenoord, A., Broekman, M. Tags: STEM CELLS Source Type: research

Impact of Covid-19 Pandemic on Neuro-Oncology Multidisciplinary Tumor Board in the Pre-Vaccine Era: the Normandy experience
CONCLUSION: The pre-vaccination era of the COVID19 pandemic did not impact the activity of neuro-oncology multidisciplinary tumor board in the Normandy region. The possible consequences in terms of public health (excess mortality) due to this tumor location should now be investigated.PMID:36870566 | DOI:10.1016/j.neuchi.2023.101429
Source: Neuro-Chirurgie - March 4, 2023 Category: Neurosurgery Authors: Marine Lacaud Arthur Leclerc Florent Marguet Maxime Faisant Paul Lesueur Houria El Ouazzani Fr édéric Di Fiore Chantal Hanzen Evelyne Emery Olivier Langlois Maxime Fontanilles Source Type: research

Sp-04 * international patterns of palliative care in neuro-oncology: a physician survey of members of the asian society of neuro-oncology, the european association of neuro-oncology and the society for neuro-oncology
CONCLUSION: This is the first report describing global differences of PC utilization in neuro-oncology. Significant differences in provider training, culture, access and utilization were mainly found between AO and the US or AO and Europe. PC patterns are more similar in Europe and the US.
Source: Neuro-Oncology - November 3, 2014 Category: Cancer & Oncology Authors: Walbert, T., Puduvalli, V., Taphoorn, M. J. B., Taylor, A. R., Jalali, R. Tags: SUPPORTIVE AND PALLIATIVE CARE Source Type: research

Epid-16. outcomes of funded neuro-oncology summer research opportunities for medical students
CONCLUSIONS:Compared to historical practice patterns, medical students who participated in neuro-oncology funded summer research opportunities are more likely to be in academia and the neuro-oncology-related fields of neurosurgery, neurology, pathology, and radiation oncology. Early funding for mentored medical student research may provide substantial ‘returns-on-investment’ in terms of future neuro-oncologic research and practice.
Source: Neuro-Oncology - November 6, 2016 Category: Cancer & Oncology Authors: Iorgulescu, J. B., Young, G., Kahl, N., Patil, A., Smith, T. Tags: EPIDEMIOLOGY Source Type: research

P21.06 The Role of Neuro-oncology Tumor Boards at Academic Centers in the United States
Tumor Boards or Multidisciplinary Cancer Meetings (MCM) are the model of care for the management of cancer patients worldwide. Many neuro-oncology conditions do not have a standard of care regimen. Optimal care for these patients requires a multidisciplinary team approach. Benefits include efficient coordination of multiple providers, direction for complicated cases, open communication amongst care teams, education, and clinical trial access. In most institutions MCMs prospectively coordinate multidisciplinary care and influence care decisions, however the exact impact is unclear. The purpose of this study is to define the...
Source: Neuro-Oncology - September 20, 2016 Category: Cancer & Oncology Authors: Snyder, J. Tags: P21 Miscellaneous Source Type: research

Rare-43. search for druggable targets in primary nervous system melanotic tumors: melanocytomas, melanotic schwannomas, primary melanomas
Due to the extreme rarity of primary nervous system melanotic tumors, relatively limited studies have been conducted attempting to identify distinguishing mutations and/or druggable targets. Melanocytomas share GNAQ mutations with uveal melanoma (Brain Pathol. 25:202-8, 2015; Acta Neuropathol 119:317-323, 2010); clinical trials in uveal melanomas have shown that MEK inhibition may result in clinical benefit in tumors with these mutations. BRAF V600E mutations (paralleled by BRAF VE1 immunohistochemistry) are targetable by vemurafenib, but large numbers of primary nervous system melanomas have not been assessed. Adding to t...
Source: Neuro-Oncology - November 6, 2016 Category: Cancer & Oncology Authors: Lillehei, K., Davies, K., Aisner, D., Kleinschmidt-DeMasters, B. K. Tags: RARE TUMORS Source Type: research

Neuro-oncology Telemedicine Follow-up Visits (P7.274)
CONCLUSIONS: These data suggest that neuro-oncology can be practiced safely and effectively using a telemedicine system, with high levels of patient satisfaction.Disclosure: Dr. Green has nothing to disclose. Dr. Woyshner has nothing to disclose. Dr. Hauser Dehaven has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Green, R., Woyshner, E., Hauser Dehaven, A. Tags: Neuro-oncology: Primary CNS Tumors: Gliomas Source Type: research

The Neurologic Assessment in Neuro-Oncology (NANO) Scale: A Tool to Assess Neurologic Function for Integration in the Radiologic Assessment in Neuro-Oncology (RANO) Criteria (S22.005)
CONCLUSIONS: The NANO criteria provide a more detailed and objective measure of neurologic function than currently exists for brain tumor patients. These criteria enable a consistent evaluation of neurologic function that can be assessed across clinical trials and therapeutic interventions. Implementation and validation of these criteria are planned and will likely be regularly refined for further optimization.Disclosure: Dr. Nayak has nothing to disclose. Dr. DeAngelis has received personal compensation for activities with the NFL Players Association as a consultant. Dr. Wen has received personal compensation for activiti...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Nayak, L., DeAngelis, L., Wen, P., Brandes, A., Soffietti, R., Lin, N., Peereboom, D., Chamberlain, M., Macdonald, D., Galanis, E., Perry, J., Jaeckle, K., Mehta, M., Stupp, R., Van Den Bent, M., Reardon, D. Tags: Neuro-oncology Source Type: research

Epid-04. tumor board conferences in neuro-oncology: a nationwide provider survey
CONCLUSION:Neuro-oncology MCMs at leading U.S. institutions show high congruity of core disciplines, cases discussed, and perceived value. There is strong agreement on the role of clinical decision making and education, but the implementation of recommendations varies widely. We identified marked variability in preparation time, documentation, and high uncertainty as to the definition and application of a molecular tumor board.
Source: Neuro-Oncology - November 6, 2016 Category: Cancer & Oncology Authors: Snyder, J., Schultz, L., Walbert, T. Tags: EPIDEMIOLOGY Source Type: research

Qlif-15. first swiss integrated multidisciplinary neurorehabilitation program for neuro-oncologic in-patients
Patients diagnosed with brain tumors are wrongly considered poor candidates for neuro-rehabilitation (NR), due to the perception of poor prognosis and the need of oncologic care following surgery. However, intensive rehabilitation often allows to improve functional independence. In this context, we have identified a need for an integrated management of neuro-oncologic patients who are not sufficiently independent to return home after neurosurgery and we set up the first Swiss neuro-rehabilitation program for neuro-oncologic patients. It is based on an innovative public-private partnership between the CHUV University Hospit...
Source: Neuro-Oncology - November 6, 2016 Category: Cancer & Oncology Authors: Hottinger, A., Moura, B., Pellet, C., Levivier, M., Berney, L., Giannelli, M., Robert, J.-P., Diserens, K. Tags: QUALITY OF LIFE Source Type: research