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Web-Based Mindfulness Interventions for People With Physical Health Conditions: Systematic Review
Conclusions: Preliminary evidence suggests that Web-based MBIs may be helpful in alleviating symptom burden that those with physical health conditions can experience, particularly when interventions are tailored for specific symptoms. There was no evidence of differences between synchronous versus asynchronous or facilitated versus self-directed Web-based MBIs. Future investigations of Web-based MBIs should evaluate the effects of program adherence, effects on mindfulness levels, and whether synchronous or asynchronous, or facilitated or self-directed interventions elicit greater improvements.
Source: Journal of Medical Internet Research - August 31, 2017 Category: General Medicine Authors: Kirsti I Toivonen Kristin Zernicke Linda E Carlson Source Type: research

Trazodone for Insomnia: A Systematic Review
Conclusion. A review of the literature suggests that there are adequate data supporting the efficacy and general safety of the low-dose use of trazodone for the treatment of insomnia. keywords: insomnia, hypnotics, treatment, trazodone, sedative Keywords: insomnia, hypnotics, treatment, trazodone, sedative Innov Clin Neurosci. 2017;14(9–10):24–34 Introduction Insomnia is characterized by difficulty falling asleep, difficulty staying asleep, or waking too early1 and is associated with significant impairments in daytime activities, which might occur despite adequate opportunities for sleep.2–6 Primary insomnia is an or...
Source: Innovations in Clinical Neuroscience - July 1, 2017 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Review hypnotics insomnia sedative trazodone treatment Source Type: research

Child Maltreatment and Mortality Disparities
Child maltreatment is a debilitating problem and a global public health issue. According to the World Health Organization, 1 in 4 adults report having been physically maltreated and 1 in 5 women disclose having been sexually abused in childhood. The extent of the problem is even larger when considering neglect as well as psychological and emotional abuse, affecting more than half of the population in many parts of the world. The child who is exposed to maltreatment may experience immediate physical injuries (eg, brain injury, fractures, bruises, and burns) as well as increased risk for longer-term suicide attempts; psychos...
Source: JAMA Psychiatry - August 17, 2016 Category: Psychiatry Source Type: research

Asbestos as a possible major cause of malignant lung tumors (including small cell carcinoma, adenocarcinoma & mesothelioma), brain tumors (i.e. astrocytoma & glioblastoma multiforme), many other malignant tumors, intractable pain including fibromyalgia, & some cardio-vascular pathology: Safe & effective methods of reducing asbestos from normal & pathological areas.
Asbestos as a possible major cause of malignant lung tumors (including small cell carcinoma, adenocarcinoma & mesothelioma), brain tumors (i.e. astrocytoma & glioblastoma multiforme), many other malignant tumors, intractable pain including fibromyalgia, & some cardio-vascular pathology: Safe & effective methods of reducing asbestos from normal & pathological areas. Acupunct Electrother Res. 2006;31(1-2):61-125 Authors: Omura Y Abstract High incidences of Small Cell Carcinoma & Adenocarcinoma of the lung, Astrocytoma & Glioblastoma Multiforme of the brain and Mesothelioma of ...
Source: Acupuncture and Electro-Therapeutics Research - November 30, 2015 Category: Complementary Medicine Tags: Acupunct Electrother Res Source Type: research

Clinical Value of Serum Neuroplasticity Mediators in Identifying the Central Sensitivity Syndrome in Patients With Chronic Pain With and Without Structural Pathology
Background and Objectives: Central sensitivity syndrome (CSS) encompasses disorders with overlapping symptoms in a spectrum of structural pathology from persistent somatic nociception (eg, osteoarthritis) to absence of tissue injury such as in fibromyalgia, chronic tension-type headache, and myofascial pain syndrome. Likewise, the spectrum of the neuroplasticity mediators associated with CSS might present a pattern of clinical utility. Methods: We studied the brain-derived neurotrophic factor (BDNF), tumor necrosis factor-α (TNF-α), and interleukins 6 (IL-6) and IL-10 in female patients with CSS absent of structural path...
Source: The Clinical Journal of Pain - October 30, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Placebo-Controlled, Double-Blind, Randomized Pilot Study to Evaluate the Effects of Low-Dose Naltrexone on Quality of Life and Fatigue in Newly Diagnosed High-Grade Glioma (P4.210)
Conclusions: Though LDN is safe to administer, LDN has no impact on QoL or fatigue in HGG patients.Disclosure: Dr. Peters has nothing to disclose. Dr. Affronti has nothing to disclose. Dr. Woodring has nothing to disclose. Dr. Lipp has nothing to disclose. Dr. Healy has nothing to disclose. Dr. McSherry has nothing to disclose. Dr. Herndon has nothing to disclose. Dr. Flahiff has nothing to disclose. Dr. Miller has nothing to disclose. Dr. Freeman has nothing to disclose. Dr. Minchew has nothing to disclose. Dr. Zalutsky has nothing to disclose. Dr. Taylor has nothing to disclose. Dr. Boulton has nothing to disclose. Dr. R...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Peters, K., Affronti, M., Woodring, S., Lipp, E., Healy, P., McSherry, F., Herndon, J., Flahiff, C., Miller, E., Freeman, M., Minchew, J., Zalutsky, B., Taylor, B., Boulton, S., Randazzo, D., DesJardins, A., Vlahovic, G., Bigner, D., Friedman, H. Tags: Neuro-oncology: Quality of Life and Symptoms Management Source Type: research

Isoflavones inhibit poly(I:C)-induced serum, brain, and skin inflammatory mediators - relevance to chronic fatigue syndrome
Conclusion: Poly(I:C) treatment decreased mouse locomotor activity and increased serum levels and brain and skin gene expression of inflammatory mediators. These effects were inhibited by isoflavones that may prove useful in CFS.
Source: Journal of Neuroinflammation - October 31, 2014 Category: Neurology Authors: Magdalini VasiadiJennifer NewmanTheoharis Theoharides Source Type: research

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