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Plasma Brain-Derived Neurotrophic Factor and Opioid Therapy: Results of Pilot Cross-Sectional Study
Conclusion: Chronic opioid therapy for noncancer pain induces specific changes in the BDNF concentration. Tramadol and buprenorphine exerted an important effect on BDNF levels in the examined patients. The BDNF level depends on duration of opioid therapy with buprenorphine, and age in tramadol therapy.PMID:36581402 | PMC:PMC9799226 | DOI:10.3121/cmr.2022.1731
Source: Clinical Medicine and Research - December 29, 2022 Category: General Medicine Authors: Ursula Kosciuczuk Piotr Jakubow Jolanta Czyzewska Pawel Knapp Ewa Rynkiewicz-Szczepanska Source Type: research
