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Cancer: Hepatocellular Carcinoma

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Total 2346 results found since Jan 2013.

Intractable Neck Pain in an Oncologic Palliative Care Setting: Is Cancer Always the Answer?
Authors: Delfine V, Bernasconi E, Bardelli D, Spataro V, Fusi-Schmidhauser T Abstract Refractory pain is a common manifestation in an oncologic palliative care setting and represents a major challenge for health care professionals involved in care provision. The underlying neoplasm and its dissemination are the foremost pathophysiologic mechanism for the development of pain in patients with advanced cancer. Nonetheless, other etiologies such as trauma and infections need to be considered by clinicians in this particular care setting. The authors present the case of a patient with a recent diagnosis of hepatocellula...
Source: Journal of Pain and Palliative Care Pharmacotherapy - March 15, 2017 Category: Palliative Care Tags: J Pain Palliat Care Pharmacother Source Type: research

Blockade of Erythropoietin-Producing Human Hepatocellular Carcinoma Receptor B1 in Spinal Dorsal Horn Alleviates Visceral Pain in Rats
CONCLUSION: EphB1 receptors in the spinal dorsal horn play a pivotal role in the development of visceral pain and may be considered as a potential target for the treatment of visceral pain.PMID:33880135 | PMC:PMC8046573 | DOI:10.1155/2021/7582494
Source: Pain Research and Management - April 21, 2021 Category: Anesthesiology Authors: Chen-Li Sun Cheng-Wen Li Nong He Yuan-Zhang Tang Xiu-Liang Li Fu-Shan Xue Jia-Xiang Ni Source Type: research

The Effects of Thoracic Epidural Analgesia during Percutaneous Radiofrequency Ablation for Hepatocellular Carcinoma.
Conclusions: Thoracic epidural analgesia was associated with shorter procedure times, lower postprocedural pain, and lower opioid consumption during and after PRFA for HCC. PMID: 30581515 [PubMed - in process]
Source: Pain Research and Management - December 26, 2018 Category: Anesthesiology Authors: Choi EJ, Choi YM, Kim HJ, Ok HG, Chang EJ, Kim HY, Yoon JU, Kim KH, Byeon GJ Tags: Pain Res Manag Source Type: research

Determination of Risk Factors for Pain After Transarterial Chemoembolization with Drug-Eluting Beads for Hepatocellular Carcinoma
Source: Journal of Pain Research - March 26, 2020 Category: Anesthesiology Tags: Journal of Pain Research Source Type: research

Transcutaneous Electrical Acupoint Stimulation for Moderate to Severe Pain in Hepatocellular Carcinoma: A Protocol for a Randomized Controlled Trial
Source: Journal of Pain Research - July 6, 2022 Category: Anesthesiology Tags: Journal of Pain Research Source Type: research

Analgesic Effect of Zanthoxylum nitidum Extract in Inflammatory Pain Models Through Targeting of ERK and NF- κB Signaling
Conclusion: The present study suggests that the extract of LMZ attenuates CFA-induced inflammatory pain by suppressing the ERK1/2 and NF-κB signaling pathway at both peripheral and central level. Introduction Pain is one of the most common symptoms in clinical practice, and inflammatory pain is the most important type of pain (Patapoutian et al., 2009). Inflammatory pain is a growing global health problem. In generally, there is a common course of progression in inflammation and pain share. When patients experience inflammation, they may develop hyperalgesia or allodynia to various mechanical, thermal, or ch...
Source: Frontiers in Pharmacology - April 23, 2019 Category: Drugs & Pharmacology Source Type: research

The effectiveness of a pain management programme on pain control and quality of life in patients with metastatic cancer
CONCLUSION: The investigated pain management programme significantly improved both pain control and QOL in metastatic cancer patients receiving systemic chemotherapy in the outpatient setting.PMID:36151980 | DOI:10.12968/ijpn.2022.28.9.436
Source: Cancer Control - September 24, 2022 Category: Cancer & Oncology Authors: Apinya Prisutkul Arunee Dechaphunkul Tippawan Arundorn Maliwan Songserm Anongnart Ruangdam Chirawadee Sathitruangsak Source Type: research

Feasibility and clinical value of computed tomography-guided125I brachytherapy for pain palliation in patients with retroperitoneal lymph node metastases
Conclusions: In the treatment of intractable carcinomatous pain in patients with retroperitoneal lymph node metastases, CT-guided125 I brachytherapy is a feasible and effective modality for pain palliation.
Source: Journal of Cancer Research and Therapeutics - May 27, 2020 Category: Cancer & Oncology Authors: Qicong Mai Zhiqiang Mo Jian He Meng Chen Qing Gou Feng Shi Xiaoming Chen Source Type: research

Predictive factors of severe abdominal pain during and after transarterial chemoembolization for hepatocellular carcinoma
ConclusionSevere abdominal pain was frequent during and after TACE revealing a clinically relevant and underestimated problem. A predictive model based on three readily available clinical variables suggests that young patients without alcoholic liver disease or cirrhosis could benefit from reinforced analgesia.Key Points• Severe abdominal pain occurs in 43% of TACE for HCC.• Younger age, absence of cirrhosis, and absence of alcoholic liver disease were identified as independent predictive factors of severe abdominal pain.• A simple combination of the three abovementioned features helped predict the occurrence of severe abdominal pain.
Source: European Radiology - April 13, 2021 Category: Radiology Source Type: research

Psychometric properties of a brief, clinically relevant measure of pain in patients with hepatocellular carcinoma
Conclusions The three FACT-Hep pain items are unidimensional, cover the range of pain experienced by most patients with HCC, and demonstrate convergent validity. This pain subscale is, if future research demonstrates its sensitivity to change, potentially useful for HCC clinical trials.
Source: Quality of Life Research - October 7, 2014 Category: Health Management Source Type: research

Tropical Travel Trouble 005 RUQ Pain and Jaundice
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog aka Tropical Travel Trouble 005 Guest Post: Dr Branden Skarpiak – Global Health Fellow, Department of Emergency Medicine. UT Health San Antonio A 35 year old male presents to your emergency room for right upper quadrant pain that has gotten worse over the last 2-3 days. He also describes associated nausea, vomiting, and fevers. He denies other abdominal pain, or change in his bowel or bladder habits. His wife notes that he has started to “look more yellow” recent...
Source: Life in the Fast Lane - March 19, 2018 Category: Emergency Medicine Authors: Neil Long Tags: Clinical Cases Tropical Medicine amebic amoeba amoebiasis amoebic dysentery amoebic liver abscess bloody diarrhoea e.dispar e.histolytica entamoeba histolytica Source Type: blogs

Association Between Activation of the Programmed Cell Death-1 (PD-1)/Programmed Death-Ligand 1 (PD-L1) Pathway and Pain in Patients with Cancer.
CONCLUSIONS The positive expression rate of sPD-1 and PD-1 in patients with cancer pain is higher than that in normal people. The activation rate of the PD-1/PD-L1 pathway was mediated by sPD-1 and PD-1 positive expression, age, tumor type, and differentiation. There are correlations between clinical characteristics such as degree and pain level as shown by VAS score. PMID: 30771277 [PubMed - in process]
Source: Medical Science Monitor - February 18, 2019 Category: Research Tags: Med Sci Monit Source Type: research

Assessment of Pain Severity after Radiofrequency Ablation in Patients with Hepatocellular Carcinoma.
CONCLUSION: The incidence of undesired pain scores after percutaneous radiofrequency ablation in our institution was around 10%, and the rate of complication was very low. PMID: 27501613 [PubMed - in process]
Source: Journal of the Medical Association of Thailand = Chotmaihet thangphaet - August 11, 2016 Category: Journals (General) Tags: J Med Assoc Thai Source Type: research

Effect of toad skin extracts on the pain behavior of cancer model mice and its peripheral mechanism of action.
Abstract The changes in thermal and mechanical hyperalgesia in paw cancer pain model mice and the action mechanism of toad skin extracts (TSE) was investigated. Eighty female mice were subcutaneously injected with saline or inoculated with H22 hepatoma cells in the right hind paw and administration with saline, vehicle, morphine and TSE. The pain behavior was recorded before treatment and at 0.5, 1.0, 1.5, 3 and 6h after initial administration, and thereafter on the 2nd, 4th, 6th, and 8th day after administration. On the last day, samples were collected after the euthanasia for the detection of β-END, CRF, IL-1β...
Source: International Immunopharmacology - November 27, 2016 Category: Allergy & Immunology Authors: Chen T, Yuan SJ, Yu XQ, Jiao LB, Hu W, Chen WL, Xie B Tags: Int Immunopharmacol Source Type: research