Filtered By:
Cancer: Prostate Cancer

This page shows you your search results in order of relevance. This is page number 11.

Order by Relevance | Date

Total 26026 results found since Jan 2013.

Modified risk stratification grouping using standard clinical and biopsy information for patients undergoing radical prostatectomy: Results from SEARCH
ConclusionsPatients classified as VHR have markedly increased rates of PSA relapse, DM, and PCSM in comparison to SHR patients, whereas UIR and SHR patients have similar prognosis. Novel therapeutic strategies are needed for patients with VHR, likely involving multimodality therapy.
Source: The Prostate - October 10, 2017 Category: Urology & Nephrology Authors: Zachary S. Zumsteg, Zinan Chen, Lauren E. Howard, Christopher L. Amling, William J. Aronson, Matthew R. Cooperberg, Christopher J. Kane, Martha K. Terris, Daniel E. Spratt, Howard M. Sandler, Stephen J. Freedland Tags: ORIGINAL ARTICLE Source Type: research

Safety and Efficacy of Prostatic Artery Chemoembolization for Prostate Cancer —Initial Experience
Conclusions Prostatic artery chemoembolization allowed a biochemical response in patients with localized PCa and is a promising treatment.
Source: Journal of Vascular and Interventional Radiology - January 22, 2018 Category: Radiology Source Type: research

Prostatic Artery Chemoembolization —A Viable Management Option for Men Diagnosed with Prostate Cancer?
Publication date: March 2018 Source:Journal of Vascular and Interventional Radiology, Volume 29, Issue 3 Author(s): Stephen H. Culp
Source: Journal of Vascular and Interventional Radiology - February 16, 2018 Category: Radiology Source Type: research

Obese Castration ‐Resistant Prostate Cancer Patients may be at a lower risk of all‐cause mortality: Results from the SEARCH Database
ConclusionsAmong non‐metastatic CRPC patients, obesity was associated with better overall survival. Although this result mirrors evidence from men with mCRPC, obesity was not associated with PC outcomes. Larger studies are needed to confirm these findings.This article is protected by copyright. All rights reserved.
Source: BJU International - March 9, 2018 Category: Urology & Nephrology Authors: Adriana C. Vidal, Lauren E. Howard, Amanda de Hoedt, Christopher J. Kane, Martha K. Terris, William J. Aronson, Matthew R. Cooperberg, Christopher L. Amling, Stephen J. Freedland Tags: Original Article Source Type: research

Lba23 four-year follow-up of a phase-3 prospective randomized trial of vascular-targeted phototherapy versus active surveillance for low-risk prostate cancer.
Partial gland ablation (PGA) for prostate cancer (PCa) is receiving more interest from patients and urologists, driven by continued improvements in PCa detection and emerging ablative technologies. While safety has been reasonably established, there is limited, if any, Level I evidence of efficacy. The prospective phase 3 trial, CLIN1001 PCM301, randomized 413 men with low-risk PCa (= 3 positive cores, 3-5 mm max cancer core length) to PGA with vascular-targeted photodynamic therapy (VTP; n=207) or active surveillance (AS; n=206).
Source: The Journal of Urology - April 1, 2018 Category: Urology & Nephrology Authors: Inderbir Gill, Mark Emberton, Abdel Azzouzi, Jonathan Coleman, Emmanuel Coeytaux, Avigdor Scherz, Peter Scardino Tags: Plenary: Next Frontier Source Type: research

Mp64-07 vascular hurst index in non-tumoral biopsy cores as potential histopathological parameter to select patients with hidden prostate cancer
It's accepted that angiogenesis is a complex phenomenon accompanying the development, progression and metastasis of tumors of unrelated histological origin. We introduce the Hurst index to investigate the two-dimensional (2-D) geometrical complexity of the tumor vascular network in biopsy specimens to comprehend whether non-tumoral biopsy cores might be helpful to select patients with hidden prostate cancer.
Source: The Journal of Urology - April 1, 2018 Category: Urology & Nephrology Authors: Fabio Grizzi, Alberto Mandressi, Piergiuseppe Colombo, Sara Melegari, Matteo Justich, Giorgio Bozzini, Mauro Seveso, Oliviero De Francesco, Nicol ò Buffi, Giovanni Lughezzani, Massimo Lazzeri, Rodolfo Hurle, Luisa Pasini, Alessio Benetti, Silvia Zandegia Tags: Prostate Cancer: Basic Research & Pathophysiology II Source Type: research

Pd34-04 biopsy outcomes and patterns of prostate cancer grade progression in the pcm301 randomized trial of vascular targeted photodynamic therapy and active surveillance: implications for focal therapy
Post-treatment biopsy findings are key endpoints for partial gland ablation (PGA) therapies including evaluation for presence of residual cancer, extent and grade that help to define surrogates of treatment success. We undertook a critical evaluation of longitudinal biopsy outcomes from the Phase 3 randomized trial of Vascular Targeted Photodynamic Therapy (VTP) vs. Active Surveillance (AS) to provide insight into site-specific procedure related findings that have not previously been reported.
Source: The Journal of Urology - April 1, 2018 Category: Urology & Nephrology Authors: Jonathan Coleman, Avigdor Scherz, Peter Scardino, Inderbir Gill, Souhil Lebdai, A. Rahmen Azzouzi, Mark Emberton Tags: Prostate Cancer: Localized: Ablative Therapy II Source Type: research

Mp11-02 outcomes of a phase iii randomized controlled trial comparing preventive versus delayed ligation of dorsal vascular complex during robot-assisted radical prostatectomy
The ligation of the dorsal vascular complex (DVC) during robot-assisted radical prostatectomy (RARP) can be done either before (preventive ligation, PL) or after  (delayed ligation, DL) its transection. We evaluated in a prospective randomized setting whether a DL of the DVC impacted on perioperative, functional and oncological outcomes as compared to PL during RARP.
Source: The Journal of Urology - April 1, 2018 Category: Urology & Nephrology Authors: Carlotta Palumbo, Alessandro Antonelli, Simone Francavilla, Marco Lattarulo, Stefania Zamboni, Alessandro Veccia, Maria Furlan, Enrico De Marzo, Angelo Peroni, Claudio Simeone Tags: Prostate Cancer: Localized: Surgical Therapy II Source Type: research

Prostatic Artery Embolization in the Treatment of Localized Prostate Cancer: A Bicentric Prospective Proof-of-Concept Study of 12  Patients
Conclusions PAE with the use of 100-μm microspheres failed to achieve complete elimination of tumor cells. Extensive tumor regression was induced in some lesions, highlighting the need for further assessment of PAE as a potential treatment option for prostate cancer.
Source: Journal of Vascular and Interventional Radiology - April 22, 2018 Category: Radiology Source Type: research

Randomized Trial of Partial Gland Ablation with Vascular-Targeted Phototherapy versus Active Surveillance for Low-risk Prostate Cancer: Extended Follow-up and Analyses of Effectiveness
The prospective trial PCM301 randomized 413 men with low-risk prostate cancer to partial gland ablation with vascular-targeted photodynamic therapy (n=207) or active surveillance (n=206). Two-year outcomes were reported previously. Here we report four-year rates of intervention with radical therapy and further assess efficacy with biopsy results.
Source: The Journal of Urology - June 1, 2018 Category: Urology & Nephrology Authors: Inderbir S. Gill, Abdel-Rahmene Azzouzi, Mark Emberton, Jonathan A. Coleman, Emmanuel Coeytaux, Avigdor Scherz, Peter T. Scardino, PCM301 Study Group Source Type: research

Randomized Trial of Partial Gland Ablation with Vascular Targeted Phototherapy versus Active Surveillance for Low Risk Prostate Cancer: Extended Followup and Analyses of Effectiveness
We report 4-year rates of intervention with radical therapy and further assess efficacy with biopsy results.
Source: The Journal of Urology - June 1, 2018 Category: Urology & Nephrology Authors: Inderbir S. Gill, Abdel-Rahmene Azzouzi, Mark Emberton, Jonathan A. Coleman, Emmanuel Coeytaux, Avigdor Scherz, Peter T. Scardino, PCM301 Study Group Tags: Adult Urology Source Type: research

Prostate Artery Embolization in Patients with Prostate Volumes of 80 mL or More: A Single-Institution Retrospective Experience of 93 Patients
ConclusionsPAE achieved a clinically and statistically significant improvement in symptom burden and secondary outcome measures in patients with PVs ≥ 80 mL. PAE may be an alternate treatment for patients for whom conventional surgical options are limited or associated with significant morbidity.
Source: Journal of Vascular and Interventional Radiology - September 12, 2018 Category: Radiology Source Type: research

Radical prostatectomy after vascular-targeted photodynamic therapy (VTP) with TOOKAD ® : feasibility, early and intermediate results
The objectives are to assess the feasibility of radical prostatectomy (RP) after VTP and describe functional and oncological outcomes.
Source: The Journal of Urology - September 21, 2018 Category: Urology & Nephrology Authors: V. Pierrard, S. Lebdai, F. Kleinclauss, A.-R. Azzouzi, J.E. Terrier, E. Fortier, S. Joniau, H. Van Der Poel, G. Salomon, J. Casanova, R.-A. Medina-Lopez, E. Potiron, J. Rigaud, S. Vincendeau, J. Rassweiler, A. Villers, R. Gaston, C. Saussine, J. Giai, B. Source Type: research

Partial gland ablation with vascular-targeted phototherapy versus active surveillance for low-risk prostate cancer : Results of a randomized trial.
Abstract PMID: 30446781 [PubMed - as supplied by publisher]
Source: Der Urologe. Ausg. A - November 16, 2018 Category: Urology & Nephrology Authors: Salomon G Tags: Urologe A Source Type: research

Clarifying the relative impacts of vascular and nerve injury that culminate in erectile dysfunction in a pilot study using a rat model of prostate irradiation and a thrombopoietin mimetic
Radiation-induced erectile dysfunction (RI-ED) following prostate cancer radiation therapy is a significant survivorship problem. The etiology of this condition has been postulated to result from injury to the penile vessels, nerves or both. To address this gap in knowledge, we applied a vascular radioprotectant to a rat model of RI-ED. Protecting the vasculature did not improve erectile function or prevent nerve injury, suggesting a critical role for RT-mediated nerve damage in RI-ED.
Source: International Journal of Radiation Oncology * Biology * Physics - December 7, 2018 Category: Radiology Authors: Kathleen A. Ashcraft, Johanna L. Hannan, Gary Eichenbaum, Xiaojie Zhang, Elena S. Pak, Austin M. Faught, Pranalee Patel, Mark W. Dewhirst, Bridget F. Koontz Tags: Biology Contribution Source Type: research