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Prostatic Artery Embolization in Refractory Hematuria of Prostatic Origin
Hematuria of prostatic origin has multiple etiologies including benign prostatic hyperplasia (BPH), iatrogenic urological trauma, prostate cancer, and radiation therapy. Hematuria secondary to benign prostatic hyperplasia can occur because of the increased vascularity of the primary gland, itself, or because of the vascular re-growth following a transurethral resection of the prostate. Prostatic hematuria usually resolves with conservative measures; however, refractory hematuria of prostatic origin may require hospitalization with treatment with blood transfusions, repeated indwelling urinary catheterization, and continuou...
Source: Techniques in Vascular and Interventional Radiology - October 5, 2020 Category: Radiology Authors: Issam Kably, Vedant Acharya, Andrew J. Richardson, Shivank Bhatia Source Type: research

Early Results of Unilateral Prostatic Artery Embolization as a Focal Therapy in Patients with Prostate Cancer under Active Surveillance: Cacer Prostate Embolisation, a Pilot Study
Publication date: Available online 25 November 2020Source: Journal of Vascular and Interventional RadiologyAuthor(s): Julien Frandon, Elsa Bey, Aymeric Hamard, Hélène Mohammad, Samia Gonzalez, Joël Greffier, Thierry Chevallier, Hélène de Forges, Jean-Paul Beregi, Stéphane Droupy
Source: Journal of Vascular and Interventional Radiology - November 27, 2020 Category: Radiology Source Type: research

In search of the correlation between nanomechanical and biomolecular properties of prostate cancer cells with different metastatic potential.
In this study, local mechanical properties of normal human prostate (RWPE-1) cells and a range of malignant (22Rv1) and metastatic prostate cells (LNCaP, Du145 and PC3) were investigated. It was found that non-malignant prostate cells are stiffer than cancer cells while the metastatic cells are much softer than malignant cells from the primary tumor site. Next, the biochemical properties of the cells were measured using confocal Raman (RS) and Fourier-transform infrared (FT-IR) spectroscopies to reveal these cells' biochemical composition as malignant transformation proceeds. Nanomechanical and biochemical profiles of five...
Source: Archives of Biochemistry and Biophysics - December 6, 2020 Category: Biochemistry Authors: Pogoda K, Pięta E, Roman M, Piergies N, Liberda D, Wróbel T, Janmey PA, Paluszkiewicz C, Kwiatek WM Tags: Arch Biochem Biophys Source Type: research

Effectiveness and safety of prostatic artery embolization for the treatment of lower urinary tract symptoms from benign prostatic hyperplasia in men with concurrent localized prostate cancer.
Publication date: Available online 29 March 2021Source: Journal of Vascular and Interventional RadiologyAuthor(s): Nainesh Parikh, Edward Keshishian, Brandon Manley, G. Daniel Grass, Javier Torres-Roca, David Boulware, Sebastien Feuerlein, Julio M. Pow-Sang, Sandeep Bagla, Kosj Yamoah, Shivank Bhatia
Source: Journal of Vascular and Interventional Radiology - March 29, 2021 Category: Radiology Source Type: research

In search of the optimal setting for statin trials in prostate cancer: the power of population-based studies
Prostate Cancer and Prostatic Diseases, Published online: 29 March 2021; doi:10.1038/s41391-021-00355-yIn search of the optimal setting for statin trials in prostate cancer: the power of population-based studies
Source: Prostate Cancer and Prostatic Diseases - March 29, 2021 Category: Urology & Nephrology Authors: Emma H. Allott Emma L. Craig Konrad H. Stopsack Source Type: research

Metastatic Prostate Cancer: In Search of More Granularity
J Clin Oncol. 2021 May 14:JCO2100643. doi: 10.1200/JCO.21.00643. Online ahead of print.NO ABSTRACTPMID:33989011 | DOI:10.1200/JCO.21.00643
Source: Clinical Prostate Cancer - May 14, 2021 Category: Cancer & Oncology Authors: Alok K Tewari Silke Gillessen Christopher J Sweeney Source Type: research

Response to the Letter to the Editors received after publication of our article: “Early results of unilateral prostatic artery embolization in patients with prostate cancer under active surveillance”
Publication date: Available online 1 June 2021Source: Journal of Vascular and Interventional RadiologyAuthor(s): Julien Frandon, Hélène de Forges, Jean-Paul Beregi, Stéphane Droupy
Source: Journal of Vascular and Interventional Radiology - June 1, 2021 Category: Radiology Source Type: research

Re: Early Results of Unilateral Prostatic Artery Embolization as a Focal Therapy in Patients with Prostate Cancer under Active Surveillance: Cancer Prostate Embolization, a Pilot Study
Publication date: Available online 4 June 2021Source: Journal of Vascular and Interventional RadiologyAuthor(s): Adithya Balasubramanian, Himanshu Nagar, Christopher E. Barbieri, Scott T. Tagawa, Timothy D. McClure
Source: Journal of Vascular and Interventional Radiology - June 5, 2021 Category: Radiology Source Type: research

Tumour irradiation combined with vascular-targeted photodynamic therapy enhances antitumour effects in pre-clinical prostate cancer
British Journal of Cancer, Published online: 21 June 2021; doi:10.1038/s41416-021-01450-6Tumour irradiation combined with vascular-targeted photodynamic therapy enhances antitumour effects in pre-clinical prostate cancer
Source: British Journal of Cancer - June 21, 2021 Category: Cancer & Oncology Authors: Hanna T. Sjoberg Yiannis Philippou Anette L. Magnussen Iain D. C. Tullis Esther Bridges Andrea Chatrian Joel Lefebvre Ka Ho Tam Emma A. Murphy Jens Rittscher Dina Preise Lilach Agemy Tamar Yechezkel Sean C. Smart Paul Kinchesh Stuart Gilchrist Danny P. Al Source Type: research

Response to the Letter to the Editor received after the publication of our article: “Early Results of Unilateral Prostatic Artery Embolization in Patients with Prostate Cancer under Active Surveillance”
Publication date: Available online 1 June 2021Source: Journal of Vascular and Interventional RadiologyAuthor(s): Julien Frandon, Hélène de Forges, Jean-Paul Beregi, Stéphane Droupy
Source: Journal of Vascular and Interventional Radiology - July 2, 2021 Category: Radiology Source Type: research

Decision Regret and Quality of Life after Focal Therapy with Vascular-Targeted Photodynamic Therapy (TOOKAD ®) for Localized Prostate Cancer
Conclusion: Only 9.7% of men (n = 3) felt a strong emotion of regret at 12 months after VTP. Level of decision regret was significantly higher in patients with local recurrence or tumor progression detected in control biopsy. QoL was stable after VTP.Urol Int
Source: Urologia Internationalis - November 23, 2021 Category: Urology & Nephrology Source Type: research

Development of a Semiautomated Search Tool to Identify Grading From Pathology Reports for Tumors of the CNS and Prostate Cancers
CONCLUSION: Semiautomated, document-based text classification using Perl coding successfully leveraged identification of WHO and Gleason grades to classify pathology records for CNS tumors and prostate cancer. The process is recommended for data quality initiatives to support cancer reporting functions, epidemiology, and research.PMID:34882482 | DOI:10.1200/CCI.21.00049
Source: Clinical Prostate Cancer - December 9, 2021 Category: Cancer & Oncology Authors: Diana Echeverria Kristen R Rossi Anna Carroll Tina Luse Christopher Rennix Source Type: research

Current evidence for focal laser ablation and vascular-targeted photodynamic therapy for localized prostate cancer: review of literature published in the last 2 years
Purpose of review Currently, a significant number of patients are diagnosed with unilateral and apparently unifocal low or intermediate-risk prostate cancer (PCa). These patients are suitable for focal therapy, thus preventing radical treatment side effects without affecting cancer control. Among focal therapy energy sources, laser-based technologies have shown promising outcomes. We aimed to summarize recent data on focal laser ablation (FLA) and vascular-targeted photodynamic therapy (VTP) for PCa. Recent findings We selected eight studies reporting data on 1155 patients with PCa who underwent laser-based foca...
Source: Current Opinion in Urology - February 1, 2022 Category: Urology & Nephrology Tags: LASER TECHNOLOGIES IN UROLOGY: Edited by Olivier Traxer and Dmitry Enikeev Source Type: research

Circulating vascular endothelial growth factor and cancer risk: A bidirectional mendelian randomization
In observational studies, circulating vascular endothelial growth factor (VEGF) has been reported to be associated with certain types of cancer. The purpose of this study was to verify whether there is a causal relationship between circulating VEGF and different types of cancer and the direction of the causal relationship. Summary statistical data were obtained from the corresponding genome-wide association studies (GWASs) to investigate the causal relationship between circulating VEGF and the risk of several cancers, including breast cancer, ovarian cancer, lung cancer, colorectal cancer, anus and anal canal cancer, prost...
Source: Frontiers in Genetics - September 7, 2022 Category: Genetics & Stem Cells Source Type: research