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Cancer: Prostate Cancer

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Total 26026 results found since Jan 2013.

Obesity and prostate cancer-specific mortality after radical prostatectomy: results from the Shared Equal Access Regional Cancer Hospital (SEARCH) database
J Freedland
Source: Prostate Cancer and Prostatic Diseases - October 3, 2016 Category: Urology & Nephrology Authors: A C Vidal L E Howard S X Sun M R Cooperberg C J Kane W J Aronson M K Terris C L Amling S J Freedland Source Type: research

Investigating the Vascular Phenotype of Subcutaneously and Orthotopically Propagated PC3 Prostate Cancer Xenografts Using Combined Carbogen Ultrasmall Superparamagnetic Iron Oxide MRI
Abstract: The aim of this study was to use the combined carbogen-ultrasmall superparamagnetic iron oxide (CUSPIO) magnetic resonance imaging (MRI) method, which uses spatial correlations in independent susceptibility imaging biomarkers, to investigate and compare the impact of tumor size and anatomical site on vascular structure and function in vivo. Mice bearing either subcutaneous or orthotopic PC3 LN3 prostate tumors were imaged at 7 T, using a multi-gradient echo sequence to quantify R2*, before and during carbogen (95% O2/5% CO2) breathing, and subsequently following intravenous administration of USPIO particles. Ca...
Source: Topics in Magnetic Resonance Imaging - October 1, 2016 Category: Radiology Tags: Review Articles Source Type: research

Prostatic Arterial Embolization for Control of Hematuria in Patients with Advanced Prostate Cancer
Publication date: February 2017 Source:Journal of Vascular and Interventional Radiology, Volume 28, Issue 2 Author(s): Jhih-Wei Chen, Ji Hoon Shin, Teng-Fu Tsao, Heung-Gyu Ko, Hyun-Ki Yoon, Ki-Chang Han, Somrach Thamtorawat, Bumsik Hong Nine patients with advanced prostate cancer (stage T4) underwent prostatic arterial embolization (PAE) for refractory prostatic hematuria. Angiograms showed prostatic neovascularity in all cases, and complete PAE was achieved in 8 cases (89% technical success rate). Gross hematuria ceased after PAE in 6 cases, translating to a 67% clinical success rate. There were no PAE-related complicati...
Source: Journal of Vascular and Interventional Radiology - January 19, 2017 Category: Radiology Source Type: research

Amino Acid Profiles of Serum and Urine in Search for Prostate Cancer Biomarkers: a Pilot Study.
Authors: Dereziński P, Klupczynska A, Sawicki W, Pałka JA, Kokot ZJ Abstract There is a great interest in searching for diagnostic biomarkers in prostate cancer patients. The aim of the pilot study was to evaluate free amino acid profiles in their serum and urine. The presented paper shows the first comprehensive analysis of a wide panel of amino acids in two different physiological fluids obtained from the same groups of prostate cancer patients (n = 49) and healthy men (n = 40). The potential of free amino acids, both proteinogenic and non-proteinogenic, as prostate cancer biomarkers and their utility in classi...
Source: International Journal of Medical Sciences - February 1, 2017 Category: Biomedical Science Tags: Int J Med Sci Source Type: research

Commentary: In search of answers regarding the benefits and harms of short term ADT for intermediate-risk prostate cancer.
Authors: Showalter TN PMID: 28263133 [PubMed - in process]
Source: Canadian Journal of Urology - March 7, 2017 Category: Urology & Nephrology Tags: Can J Urol Source Type: research

Vascular-Targeted Photodynamic Therapy with Padeliporfin for Low Risk Prostate Cancer Treatment: Mid-Term Oncological Outcomes
To assess the mid-term oncological outcomes of vascular-targeted photodynamic therapy with padeliporfin for low-risk prostate cancer treatment.
Source: The Journal of Urology - March 17, 2017 Category: Urology & Nephrology Authors: Souhil Lebdai, Pierre Bigot, Pierre-Adrien Leroux, Louis-Paul Berthelot, Pierre Maulaz, Abdel-Rahmene Azzouzi Source Type: research

Correspondence Padeliporfin vascular-targeted photodynamic therapy versus active surveillance in men with low-risk prostate cancer
This study is of great clinical significance, but we have some concerns and ideas to share with the authors.
Source: The Lancet Oncology - March 29, 2017 Category: Cancer & Oncology Authors: Weigang Yan, Yi Zhou, Zhien Zhou, Zhigang Ji, Hanzhong Li Tags: Correspondence Source Type: research

Retrospective Review of Percutaneous Image-Guided Ablation of Oligometastatic Prostate Cancer: A Single-Institution Experience
Conclusions In this cohort of patients with oligometastatic prostate cancer, percutaneous image-guided ablation was feasible and well tolerated and achieved acceptable local tumor control rates. Percutaneous ablation may be of particular utility in patients who wish to delay initiation of ADT.
Source: Journal of Vascular and Interventional Radiology - April 21, 2017 Category: Radiology Source Type: research

Vascular Targeted Photodynamic Therapy with Padeliporfin for Low Risk Prostate Cancer Treatment: Midterm Oncologic Outcomes
We assessed the midterm oncologic outcomes of vascular targeted photodynamic therapy with padeliporfin for low risk prostate cancer treatment.
Source: The Journal of Urology - March 18, 2017 Category: Urology & Nephrology Authors: Souhil Lebdai, Pierre Bigot, Pierre-Adrien Leroux, Louis-Paul Berthelot, Pierre Maulaz, Abdel-Rahmene Azzouzi Tags: Adult Urology Source Type: research

In vivo hemin conditioning targets the vascular and immunological compartments and restrains prostate tumor development.
Conclusions: These results highlight a novel function of a human-used drug as a means of boosting the antitumor response. PMID: 28512172 [PubMed - as supplied by publisher]
Source: Clinical Cancer Research - May 16, 2017 Category: Cancer & Oncology Authors: Jaworski FM, Gentilini L, Gueron G, Meiss RP, Ortiz EG, Berguer PM, Ahmed A, Navone NM, Rabinovich GA, Compagno D, Laderach DJ, Vazquez ES Tags: Clin Cancer Res Source Type: research

CT –Guided Bone Biopsies in Metastatic Castration-Resistant Prostate Cancer: Factors Predictive of Maximum Tumor Yield
Conclusions Image-guided bone tumor biopsies can be successfully used to acquire cellular and molecular material for analyses in patients with osteoblastic prostate cancer metastases. Diagnostic yields are significantly increased in lesions with areas of radiolucency, density ≤ 475 HU, ill-defined margins, and interval growth and in patients with alkaline phosphatase > 110 U/L.
Source: Journal of Vascular and Interventional Radiology - May 25, 2017 Category: Radiology Source Type: research

Commentary on: Padeliporfin Vascular-targeted Photodynamic Therapy Versus Active Surveillance in Men With Low-risk Prostate Cancer (CLIN1001 PCM301): An Open-label, Phase 3, Randomized Controlled Trial
zzouzi et  al report on a multicenter randomized controlled trial comparing padeliporfin (TOOKAD) vascular-targeted focal photodynamic therapy (PDT) to active surveillance (AS) for patients with low-risk prostate cancer.1 Padeliporfin is a photosensitizer that absorbs light and generates reactive oxygen spec ies, which induce thrombosis and tissue ischemia.
Source: Urology - March 22, 2017 Category: Urology & Nephrology Authors: James Johnston, Werner J. Struss, Peter C. Black Tags: Journal Watch Source Type: research

Decipher the Biology of Lethal Prostate Cancer —Using Urine Metabolomics Profiling to Search for Predictive and Prognostic Markers for Treatment Outcomes in Prostate Cancer Patients
Condition:   Using Urine Metabolomics Profiling to Search for Predictive and Prognostic Markers for Treatment Outcomes in Prostate Cancer Patients Intervention:   Other: No intervention required Sponsor:   National Taiwan University Hospital Not yet recruiting - verified July 2017
Source: ClinicalTrials.gov - July 30, 2017 Category: Research Source Type: clinical trials