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Condition: Bleeding
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Total 47301 results found since Jan 2013.
Outcome of cancer patients after atrial fibrillation ablation: Insights from the China-AF registry
CONCLUSIONS: This study suggests that catheter ablation could be feasible for rhythm control of AF patients with concomitant cancer.PMID:37736690 | DOI:10.1111/pace.14830
Source: Cancer Control - September 22, 2023 Category: Cancer & Oncology Authors: Xiaodong Peng Liu He Nian Liu Yanfei Ruan Xin Zhao Xueyuan Guo Wei Wang Songnan Li Ribo Tang Caihua Sang Chenxi Jiang Ronghui Yu Deyong Long Xin Du Jianzeng Dong Changsheng Ma Source Type: research
Cold snare endoscopic mucosal resection for colon polyps: a systematic review and meta-analysis
Conclusion CS-EMR demonstrated an excellent safety profile for colon polyps, with variable recurrence rates based on polyp size and histology. Large prospective studies are needed to validate these findings. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text
Source: Endoscopy - September 22, 2023 Category: Gastroenterology Authors: Abdallah, Mohamed Ahmed, Khalid Abbas, Daniyal Mohamed, Mouhand F. H. Suryawanshi, Gaurav McDonald, Nicholas Wilson, Natalie Umar, Shifa Shaukat, Aasma Bilal, Mohammad Tags: Systematic review Source Type: research
Does heparin rebound lead to postoperative blood loss in patients undergoing cardiac surgery with cardiopulmonary bypass?
CONCLUSION: The influence of heparin rebound on postoperative bleeding seems to be negligible, but might get significant in conjunction with incomplete heparin reversal or other coagulopathies. For that reason, it might be useful to get a picture of the entire coagulation spectrum after cardiac surgery, as can be done by the use of a viscoelastic test in conjunction with an aggregometry test.PMID:37734336 | DOI:10.1177/02676591231199218
Source: Perfusion - September 21, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Marije Rijpkema Eline A Vlot Marco C Stehouwer Peter Bruins Source Type: research
Risk-Directed Ambulatory Thromboprophylaxis in Lung and Gastrointestinal Cancers: The TARGET-TP Randomized Clinical Trial
CONCLUSIONS AND RELEVANCE: In this randomized clinical trial of individuals with lung and gastrointestinal cancers who were stratified by risk score according to thrombosis risk, risk-directed thromboprophylaxis reduced thromboembolism with a desirable number needed to treat, without safety concerns, and with reduced mortality. Individuals at low risk avoided unnecessary intervention. The findings suggest that biomarker-driven, risk-directed primary thromboprophylaxis is an appropriate approach in this population.TRIAL REGISTRATION: ANZCTR Identifier: ACTRN12618000811202.PMID:37733336 | DOI:10.1001/jamaoncol.2023.3634
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Marliese Alexander Sam Harris Craig Underhill Javier Torres Sharad Sharma Nora Lee HuiLi Wong Richard Eek Michael Michael Jeanne Tie Jennifer Rogers Alexander G Heriot David Ball Michael MacManus Rory Wolfe Benjamin J Solomon Kate Burbury Source Type: research
Neutralizing antidrug antibody to emicizumab in patients with severe hemophilia A: Case report of a first noninhibitor patient and review of the literature
CONCLUSION: Although emicizumab is very effective and has minimal immunogenicity, ADAs, albeit rare, can still occur. There have been 4 previously published anti-emicizumab ADA cases with severe HA with inhibitors, and herein, we describe 1 new case with severe HA without inhibitors.PMID:37732158 | PMC:PMC10507376 | DOI:10.1016/j.rpth.2023.102194
Source: Thrombosis and Haemostasis - September 21, 2023 Category: Hematology Authors: Hande Kizilocak Michael F Guerrera Guy Young Source Type: research
Targeting the microenvironment in the treatment of arteriovenous malformations
AbstractExtracranial arteriovenous malformations (AVMs) are regarded as rare diseases and are prone to complications such as pain, bleeding, relentless growth, and high volume of shunted blood. Due to the high vascular pressure endothelial cells of AVMs are exposed to mechanical stress. To control symptoms and lesion growth pharmacological treatment strategies are urgently needed in addition to surgery and interventional radiology. AVM cells were isolated from three patients and exposed to cyclic mechanical stretching for 24 h. Thalidomide and bevacizumab, both VEGF inhibitors, were tested for their ability to prevent th...
Source: Angiogenesis - September 21, 2023 Category: Molecular Biology Source Type: research
Nationwide Study in France To Predict One Year Major Bleeding and Validate the OAC3-PAD Score in Patients Undergoing Revascularisation for Lower Extremity Arterial Disease
Antithrombotic strategies are currently recommended for the treatment of lower extremity artery disease (LEAD) but specific scores to assess the risk of bleeding in these patients are scarce. To fill the gap, the OAC3-PAD bleeding score was recently developed and validated in German cohorts. The aim of this study was to determine whether this score performs appropriately in another real world nationwide cohort.
Source: Journal of Vascular Surgery - September 20, 2023 Category: Surgery Authors: F. Lareyre, C.-A. Behrendt, C. Pradier, N. Settembre, A. Chaudhuri, R. Fabre, J. Raffort, L. Bailly Source Type: research
Efficacy and safety of low dose, weight-based subcutaneous enoxaparin protocol in recurrent arteriovenous access thrombosis
This study aims to evaluate the safety and efficacy of a short-term, low dose, weight-based subcutaneous enoxaparin protocol (SEP) in maintaining the patency of arteriovenous (AV) access with recurrent thrombosis.METHODS: Prospective follow-up of 25 patients who presented to a tertiary institution with recurrent AV access thrombosis and treated with anticoagulation according to SEP following successful thrombectomy. Patency and safety outcomes of SEP were studied.RESULTS: The participants were 66.4 ± 10.2 years old and predominantly male (60%) and of Chinese ethnicity (72%). The AV accesses had a median age of 1.4 (0.6, 5...
Source: The Journal of Vascular Access - September 20, 2023 Category: Surgery Authors: Chye Chung Gan Ru Yu Tan May Anne Cheong Suh Chien Pang Ren Kwang Alvin Tng Chee Wooi Tan Lai Heng Lee Heng Joo Ng Kiang Hiong Tay Tze Tec Chong Chieh Suai Tan Source Type: research
Comparison of proximal gastrectomy with double-flap technique and double-tract reconstruction for proximal early gastric cancer: a meta-analysis
AbstractSurgical resection is the main treatment for proximal gastric cancer, but there is no consensus on its reconstruction. We carried out a meta-analysis to evaluate the effects of double-tract reconstruction (DTR) and double-flap technique (DFT) on postoperative quality of life in patients with proximal gastric cancer. Systematic searches of PubMed, Web of Science, EBSCO, and the Cochrane Library were performed. Literature for the last 5 years was searched without language restrictions. The cutoff date for the search was 12 April 2023. Literature and research searches were conducted independently by two researchers ...
Source: Updates in Surgery - September 20, 2023 Category: Surgery Source Type: research
Recrudescent Heparin Induced Thrombocytopenia After Therapeutic Plasma Exchange in a Patient Undergoing Thoracic Aortic Replacement
Management of patients with heparin induced thrombocytopenia (HIT) undergoing complex cardiac surgery remains a major challenge in cardiothoracic anesthesiology. Anticoagulation strategies for cardiopulmonary bypass (CPB) in these patients include use of direct thrombin inhibitors (DTIs) or desensitization strategies such as preoperative therapeutic plasma exchange (TPE) to remove antibodies and allow for systemic anticoagulation with heparin during surgery.1, 2 The major risk of using a DTI for systemic anticoagulation during CPB is severe bleeding, and hence many centers use alternative strategies such as preoperative TP...
Source: Journal of Cardiothoracic and Vascular Anesthesia - September 20, 2023 Category: Anesthesiology Authors: Louise Man, Kenan Yount, Alison Grazioli, Anand Padmanabhan, Robert Thiele, Hillary S. Maitland, Michael Mazzeffi Tags: Case Report Source Type: research
Long-term functional outcomes and complications of microsurgical resection of brainstem cavernous malformations: a systematic review and meta-analysis
AbstractBrainstem cavernous malformations (CMs) encompass up to 20% of all intracranial CMs and are considered more aggressive than cerebral CMs because of their high annual bleeding rates. Microsurgical resection remains the primary treatment modality for CMs, but long-term functional outcomes and complications are heterogenous in the literature. The authors performed a systematic review on brainstem CMs in 4 databases: PubMed, EMBASE, Cochrane library, and Google Scholar. We included studies that reported on the long-term functional outcomes and complications of brainstem CMs microsurgical resection. A meta-analysis was ...
Source: Neurosurgical Review - September 20, 2023 Category: Neurosurgery Source Type: research
Comparison of the efficacy and safety of different surgical procedures for patients with hemorrhoids: a network meta-analysis
ConclusionCurrent evidence suggests that L is best at reducing mean operative time and intraoperative bleeding, T-S is best at reducing mean length of stay, TST has the shortest time to first defecation, STARR is best at reducing recurrence rates, PPH is best at reducing postoperative anal stricture, and F is best at reducing postoperative pain after 24 h.
Source: Techniques in Coloproctology - September 19, 2023 Category: Surgery Source Type: research
Efficacy of prompt administration of cryoprecipitate in severe postpartum hemorrhage of preeclampsia patients
CONCLUSION: Prompt replenishment of coagulation factors using CRYO to patients with PE who experience severe PPH could decrease further bleeding.PMID:37723942 | DOI:10.1111/jog.15792
Source: Cell Research - September 19, 2023 Category: Cytology Authors: Keisuke Nakajima Tatsuya Fujii Takayuki Iriyama Mari Ichinose Masatake Toshimitsu Seisuke Sayama Takahiro Seyama Keiichi Kumasawa Toshiyuki Ikeda Yutaka Osuga Source Type: research
