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Condition: Diabetes Mellitus
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Total 39035 results found since Jan 2013.
Association between different modalities of insulin administration and metabolic dysfunction-associated fatty liver disease in adults with type 1 diabetes mellitus
CONCLUSION: The lower prevalence of MAFLD with coexisting significant fibrosis we observed in adults with T1DM using CSII therapy, compared to those using MDI therapy, is primarily mediated by inter-group differences in age.PMID:37708990 | DOI:10.1016/j.diabet.2023.101477
Source: Diabetes and Metabolism - September 14, 2023 Category: Endocrinology Authors: Alessandro Csermely Alessandro Mantovani Mario Luca Morieri Luisa Palmisano Maria Masulli Efisio Cossu Marco Giorgio Baroni Katia Bonomo Flavia Agata Cimini Gisella Cavallo Raffaella Buzzetti Carmen Mignogna Frida Leonetti Simonetta Bacci Roberto Trevisan Source Type: research
Compound c17 alleviates inflammatory cardiomyopathy in streptozotocin-induced diabetic mice by targeting MyD88
CONCLUSIONS: In conclusion, the small-molecule MyD88 inhibitor, c17, effectively combated the inflammatory DCM, therefore could be a potential candidate for the treatment of this disease.PMID:37703787 | DOI:10.1016/j.intimp.2023.110863
Source: International Immunopharmacology - September 13, 2023 Category: Allergy & Immunology Authors: Qianhui Zhang Weiwei Zhu Shuaijie Lou Hongdan Bao Yafen Zhou Zhaohong Cai Jiaxi Ye Yaqian Cui Minxiu Wang Leiming Jin Guang Liang Wu Luo Yi Wang Source Type: research
Prospective Nutraceutical Effects of Cinnamon Derivatives Against Insulin Resistance in Type II Diabetes Mellitus-Evidence From the Literature
Dose Response. 2023 Sep 10;21(3):15593258231200527. doi: 10.1177/15593258231200527. eCollection 2023 Jul-Sep.ABSTRACTApart from advances in pharmaceutical antidiabetic agents, efforts are being made toward hypoglycemic agents derived from natural sources. Cinnamon has been reported to have significant benefits for human health, particularly as an anti-inflammatory, antidiabetic, and anti-hypertriglyceridemic agent. The phytochemicals in cinnamon can be extracted from different parts of plant by distillation and solvent extraction. These chemicals help in decreasing insulin resistance and can act against hyperglycemia and d...
Source: Dose Response - September 13, 2023 Category: Drugs & Pharmacology Authors: Saima Naz Mohsin Faiza Saleem Ayesha Humayun Afifa Tanweer Ambreen Muddassir Source Type: research
LncRNA XIST promotes insulin resistance in gestational diabetes mellitus via the microRNA-181b-5p/NDRG2 axis
This study was designed to unravel the regulatory mechanism of XIST on animal models of gestational diabetes mellitus (GDM) progression via the microRNA (miR)-181b-5p/N-myc downstream-regulated gene 2 (NDRG2) axis. XIST, miR-181b-5p, and NDRG2 expression levels in GDM mice were detected. The GDM mice were subjected to gain- and loss-of-function assays to examine the change of glucose metabolism indices (fasting blood glucose (FBG), fasting insulin (FINS) and homeostasis model assessment of insulin resistance (HOMA-IR)), serum oxidative stress factors (glutathione (GSH), superoxide dismutase (SOD), and malondialdehyde (MDA)...
Source: General Physiology and Biophysics - September 13, 2023 Category: Physiology Authors: Yanli Xu Xiaodi Kang Huafang Liu Hongli Jiang Wenjing Wang Source Type: research
Erythema Multiforme: Unveiling the Unusual Effect of an Ayurvedic Medication 'Jambavasa' Used in the Treatment of Type 2 Diabetes Mellitus
Cureus. 2023 Aug 10;15(8):e43306. doi: 10.7759/cureus.43306. eCollection 2023 Aug.ABSTRACTErythema multiforme (EM) is a rare immune-mediated condition that can manifest as cutaneous, mucosal, or both types of lesions. The target lesion, with concentric zones of color change, is a cutaneous feature that is typical of this illness. Despite the fact that a number of factors can lead to EM, the most common being Herpes simplex virus (HSV) infection, drug-induced EM is a rare entity. As disease severity and mucosal involvement vary across individuals, treatment should be optimized for each patient, considering the risk versus b...
Source: Herpes - September 13, 2023 Category: Infectious Diseases Authors: Rinkle Gemnani Satish Mahajan Keyur Saboo Utkarsh Pradeep Aman Gupta Source Type: research
LncRNA XIST promotes insulin resistance in gestational diabetes mellitus via the microRNA-181b-5p/NDRG2 axis
This study was designed to unravel the regulatory mechanism of XIST on animal models of gestational diabetes mellitus (GDM) progression via the microRNA (miR)-181b-5p/N-myc downstream-regulated gene 2 (NDRG2) axis. XIST, miR-181b-5p, and NDRG2 expression levels in GDM mice were detected. The GDM mice were subjected to gain- and loss-of-function assays to examine the change of glucose metabolism indices (fasting blood glucose (FBG), fasting insulin (FINS) and homeostasis model assessment of insulin resistance (HOMA-IR)), serum oxidative stress factors (glutathione (GSH), superoxide dismutase (SOD), and malondialdehyde (MDA)...
Source: General Physiology and Biophysics - September 13, 2023 Category: Physiology Authors: Yanli Xu Xiaodi Kang Huafang Liu Hongli Jiang Wenjing Wang Source Type: research
Long-term aspirin administration suppresses inflammation in diabetic cystopathy
Aging (Albany NY). 2023 Sep 12;15. doi: 10.18632/aging.205021. Online ahead of print.ABSTRACTDiabetic cystopathy (DCP) is one of the most common and troublesome urologic complications of diabetes mellitus, characterized by chronic low-grade inflammatory response. However, the correlation between inflammation and disease progression remains ambiguous and effective drugs interventions remain deficient. Herein, during 12-week study, 48 male Sprague-Dawley rats were randomly assigned to four groups: negative control (NC), NC treated with aspirin (NC+Aspirin), DCP, and DCP treated with aspirin (DCP+Aspirin). Type 1 diabetes mel...
Source: Aging - September 13, 2023 Category: Biomedical Science Authors: Huifang Du Feihong Xu Jingxuan Liu Jiakui Zhang Yinhua Qin Youqian Xu Ning Li Source Type: research
Risk factors for the occurrence of infection in patients with oral squamous cell carcinoma after restorative reconstruction and its impact on recurrence and quality of life: a retrospective cohort study
CONCLUSIONS: The incidence of postoperative infection after restorative and reconstructive surgery for OSCC deserves the attention of clinicians. For high-risk infected persons, relevant anti-infection measures should be taken early against the infectious source, and the possibility of nosocomial infection should be attached great importance in clinical work. After discharge, patients should also actively do follow-up, education and other related work to reduce the incidence of postoperative infection.PMID:37701120 | PMC:PMC10493792 | DOI:10.21037/tcr-23-1150
Source: Cell Research - September 13, 2023 Category: Cytology Authors: Miaomiao Shen Weilan Shan Siyi Lv Kuan Cai Xuan Chen Zhengyun Xu Mingjin Gao Guodong Wang Source Type: research
Association of interleukin 6 and uric acid levels in patients with type 2 diabetes mellitus
Bioinformation. 2022 Dec 31;18(12):1136-1140. doi: 10.6026/973206300181136. eCollection 2022.ABSTRACTType 2 Diabetes Mellitus (T2DM) patients with coronary artery disease (CAD) coupled with hypertension (HTN) are leading cause of morbidity and mortality. Association of Interleukin 6 and uric acid levels can be used for early detection of CAD in patients with T2DM. This cross sectional study included 120 study participants, were sub grouped into three Group 1: controls (n=30), Group 2: CAD, HTN without T2DM (n=30) and Group 3: CAD, HTN with T2DM (n=30). Basic biochemical, clinical and experimental parameters were analysed a...
Source: Bioinformation - September 13, 2023 Category: Bioinformatics Authors: Setty Raghav Gutlur Nagarajaiah Pallavi Somashekar Rangaswamaiah Hareesh Ganesh Veluri Source Type: research
Urinary nephrin linked nephropathy in type-2 diabetes mellitus
This study concluded significantly elevated levels of urinary nephrin might be used for early diagnosis and prognostic marker for nephropathy in type 2 diabetes mellitus.PMID:37701508 | PMC:PMC10492904 | DOI:10.6026/973206300181131
Source: Bioinformation - September 13, 2023 Category: Bioinformatics Authors: Hareesh Rangaswamaiah Pallavi Somashekar Raghav Gutlur Nagarajaiah Setty Veluri Ganesh Source Type: research
Variability in Plasma Lipids Between Intensive Statin Therapy and Conventional-Dose Statins Combined with Ezetimibe Therapy in Patients with Coronary Atherosclerosis Disease
In this study, we aimed to examine the variability in plasma lipids under two different lipid-lowering regimens (intensive statin therapy versus the combination of conventional-dose statins with ezetimibe). In total, we have retrospectively examined 1275 patients with CAD from January 2009 to April 2019 and divided them into two groups: intensive statin group and conventional-dose statins combined with ezetimibe group. All patients were followed up for at least 1 year. Lipid variability was verified by standard deviation (SD), coefficient of variation (CV), and variability independent of mean (VIM) triple methods. Multiple...
Source: Atherosclerosis - September 13, 2023 Category: Cardiology Authors: Jinhua Jin Liwen Shan Manjun Wang Lu Liu Tian Xu Duanbin Li Zhezhe Chen Xianglan Liu Wenbin Zhang Ya Li Source Type: research
Association of interleukin 6 and uric acid levels in patients with type 2 diabetes mellitus
Bioinformation. 2022 Dec 31;18(12):1136-1140. doi: 10.6026/973206300181136. eCollection 2022.ABSTRACTType 2 Diabetes Mellitus (T2DM) patients with coronary artery disease (CAD) coupled with hypertension (HTN) are leading cause of morbidity and mortality. Association of Interleukin 6 and uric acid levels can be used for early detection of CAD in patients with T2DM. This cross sectional study included 120 study participants, were sub grouped into three Group 1: controls (n=30), Group 2: CAD, HTN without T2DM (n=30) and Group 3: CAD, HTN with T2DM (n=30). Basic biochemical, clinical and experimental parameters were analysed a...
Source: Bioinformation - September 13, 2023 Category: Bioinformatics Authors: Setty Raghav Gutlur Nagarajaiah Pallavi Somashekar Rangaswamaiah Hareesh Ganesh Veluri Source Type: research
