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Total 674 results found since Jan 2013.

Clinical Characteristics and Medication Uses Among Fibromyalgia Patients Newly Prescribed Amitriptyline, Duloxetine, Gabapentin, or Pregabalin
ConclusionPatients who started 1 of the 4 common drugs for fibromyalgia similarly had multiple comorbidities and other fibromyalgia‐related medication use, but continued the treatment only for a short time. The dose of the 4 drugs was not increased in most patients during the followup period.
Source: Arthritis Care and Research - October 28, 2013 Category: Rheumatology Authors: Seoyoung C. Kim, Joan E. Landon, Daniel H. Solomon Tags: Fibromyalgia Source Type: research

Chronic widespread pain and fibromyalgia syndrome
Abstract: Chronic widespread pain (CWP) and fibromyalgia syndrome (FMS) overlap with chronic fatigue syndrome (CFS). Several key tender trigger points are used to define FMS. Other symptoms reported commonly by patients with FMS include reduced pain threshold, fatigue, depression, anxiety, sleep disturbance, memory loss and problems with cognition, headache, migraine, diffuse abdominal pain with changes of bowel habit (irritable bowel syndrome), and urinary frequency. The pathogenesis of these syndromes is not clear, but hyperexcitability of the central and peripheral nervous systems, changes in function of pain receptors,...
Source: Medicine - March 31, 2014 Category: Internal Medicine Authors: Michael Shipley Tags: Fibromyalgia and chronic pain syndrome Source Type: research

Differential Neuroplastic Changes in Fibromyalgia and Depression Indexed by Up-Regulation of Motor Cortex Inhibition and Disinhibition of the Descending Pain System: An Exploratory Study
Conclusion: These findings support the hypothesis that in FM a deteriorated function of cortical inhibition, indexed by a higher SICI parameter, a lower function of the DPMS, together with a higher level of BDNF indicate that FM has different pathological substrates from depression. They suggest that an up-regulation phenomenon of intracortical inhibitory networks associated with a disruption of the DPMS function occurs in FM. Introduction Major depressive disorder (MDD) and fibromyalgia (FM) present overlapped symptoms. Although the connection between these two disorders has not been elucidated yet, the disruption...
Source: Frontiers in Human Neuroscience - April 24, 2019 Category: Neuroscience Source Type: research

The prevalence and clinical features of fibromyalgia in Chinese hospital  patients with primary headache: The survey of fibromyalgia comorbid with headache
CONCLUSIONS: The prevalence of fibromyalgia in mainland Chinese patients with primary headache was 6.0%. Fibromyalgia was more common in those with chronic rather than episodic headache. The most common sites of fibromyalgia pain were the neck, shoulders, and back.PMID:36651491 | DOI:10.1111/head.14443
Source: Headache - January 18, 2023 Category: Neurology Authors: Zhao Dong Kaiming Liu Huanxian Liu Zhihua Jia Wei Gui Ming Dong Yingying Cheng Yudan Lv Kang Qu Hongru Zhao Jianjun Chen Dan Zhang Zhiliang Fan Xiaosu Yang Dongmei Hu Yanbo Zhang Hongyan Xie Mingxin Li Bing Wen Sufen Chen Peng Xu Qingqing Rong Qiu He Zhan Source Type: research

Subjective Experiences and Sensitivities in Women with Fibromyalgia: A Quantitative and Comparative Study.
This study presents subjective experiences and sensitivities reported by fibromyalgia patients, which should be considered in primary care to avoid medical nomadism, as well as stigmatization of the patients. The prevalence of significant characteristics was compared with others patients consulting at the same pain unit who suffer from rebel and disabling form of chronic migraine. Psychometric tests were anonymously completed by 78 patients of the Pain Unit (44 fibromyalgia patients and 34 migraine patients). Tests evaluated pain (Visual Analog scale), childhood traumas (Childhood Trauma Questionnaire), lack of parental af...
Source: Pain Research and Management - May 31, 2018 Category: Anesthesiology Authors: De Roa P, Paris P, Poindessous JL, Maillet O, Héron A Tags: Pain Res Manag Source Type: research

Fibromyalgia in migraine: a retrospective cohort study
ConclusionPatients with comorbid fibromyalgia and migraine report more depressive symptoms, higher headache intensity, and are more likely to have severe headache related disability as compared to controls without fibromyalgia. Clinicians who care for patients with migraine may consider screening for comorbid fibromyalgia particularly in patients with moderate to severe depressive symptoms, high headache intensity and/or high headache related disability. This is the first matched study to look at these characterisitcs, and it replicates previous findings from unmatched studies.
Source: The Journal of Headache and Pain - July 31, 2018 Category: Neurology Source Type: research

Possible Molecular Mediators Involved and Mechanistic Insight into Fibromyalgia and Associated Co-morbidities.
Abstract Fibromyalgia is a chronic complex syndrome of non-articulate origin characterized by musculoskeletal pain, painful tender points, sleep problems and co-morbidities including depression, migraine. The etiopathogenesis of fibromyalgia is complex, variable and remains inconclusive. The etiological factors that have been defined include stress, genetic predisposition and environmental components. As per the reports of the American College of Rheumatology (ACR) the prevalence of fibromyalgia varies from 2 to 22% among the general population with poor diagnostic features primarily pain. Fibromyalgia encompasses...
Source: Neurochemical Research - April 18, 2019 Category: Neuroscience Authors: Singh L, Kaur A, Bhatti MS, Bhatti R Tags: Neurochem Res Source Type: research

Frequency of Migraine Headaches in Patients With Fibromyalgia.
CONCLUSION: The results of this study suggest that migraine headaches are common in patients with fibromyalgia. Clinicians who care for either population must be aware that these conditions commonly overlap and can significantly increase a patient's cumulative disease burden. PMID: 25994041 [PubMed - as supplied by publisher]
Source: Headache - May 21, 2015 Category: Neurology Authors: Vij B, Whipple MO, Tepper SJ, Mohabbat AB, Stillman M, Vincent A Tags: Headache Source Type: research

Cumulative effect of AOC1 gene variants on symptoms and pathological conditions in adult women with fibromyalgia: a pilot study
Conclusion: This study constitutes the first step in investigating associations between fibromyalgia symptoms and candidate variants of the AOC1 gene in DAO enzyme activity. Identification of reduced DAO activity may improve the quality of life and treatment of symptoms in fibromyalgia patients.
Source: Frontiers in Genetics - June 9, 2023 Category: Genetics & Stem Cells Source Type: research

(210) Prevalence of migraine headaches in patients with Fibromyalgia
Several studies have reported a high prevalence of fibromyalgia in patients with migraines,1 but there is little research on the prevalence of migraines in patients with fibromyalgia, despite clinical observation suggesting that migraines are a common complaint. Given the high degree of comorbidity between fibromyalgia and migraines, assessment of headache in patients with fibromyalgia is important. A total of 3,717 patients in the Mayo Clinic Fibromyalgia Registry who had previously agreed to be contacted regarding fibromyalgia research were sent an electronic survey consisting of medical history and demographic questions...
Source: The Journal of Pain - March 27, 2015 Category: Materials Science Authors: B. Vij, M. Whipple, S. Tepper, A. Mohabbat, M. Stillman, A. Vincent Source Type: research