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Condition: Obesity
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Hepcidin and inflammation associated with iron deficiency in childhood obesity - A systematic review
CONCLUSIONS: Obesity's chronic inflammation state leads to the production of IL-6, which acts as a signaling molecule for hepcidin synthesis, resulting in iron deficiency, which is common in obese children and adolescents who respond inadequately to iron supplementation. On the other hand, that population responds adequately to therapeutic intervention programs that lead to weight loss, guaranteeing iron homeostasis improvement. Therefore, perhaps it is time to discuss serum hepcidin level quantification as part of evaluating children and adolescents with iron deficiency, which could guide clinical choices that might lead ...
Source: Jornal de Pediatria - August 4, 2023 Category: Pediatrics Authors: Pedro Ferro Berton Alessandra Gambero Source Type: research
Evaluation of cardiac autonomic function and low-grade inflammation in children with obesity living in the Northeast Brazilian region
CONCLUSIONS: The findings suggest that children with obesity have impaired autonomic function and systemic low-grade inflammation compared to children within the normal weight range, the inflammatory biomarkers were correlated with HRV parameters in schoolchildren living in the northeastern region of Brazil.PMID:37597533 | DOI:10.1016/j.jped.2023.07.003
Source: Jornal de Pediatria - August 19, 2023 Category: Pediatrics Authors: Paulo C ésar Trindade Costa Joelma Rodrigues de Souza Poliana Correia Lima Davyson Barbosa Duarte Thallyta Alanna Ferreira Viana das Neves Joicy Karla Grangeiro Pereira Cristiane Cosmo Silva-Luis R úbia Cartaxo Squizato de Moraes Valdir de Andrade Braga Source Type: research
