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Condition: Hypertension
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Total 62589 results found since Jan 2013.
Tracheal suction at birth in non-vigorous neonates born through meconium-stained amniotic fluid
CONCLUSIONS: We are uncertain about the effect of tracheal suction on the incidence of MAS and its complications among non-vigorous neonates born through MSAF. One study awaits classification and could not be included in the review. More research from well-conducted large trials is needed to conclusively answer the review question.PMID:34133025 | DOI:10.1002/14651858.CD012671.pub2
Source: Cochrane Database of Systematic Reviews - June 16, 2021 Category: General Medicine Authors: Sushma Nangia Anu Thukral Deepak Chawla Source Type: research
Coupons, PBM ' s ... oh my!
Over the past few years, my coverage of coupon-generating websites/apps has increased by a lot in this blog because those have emerged as a critical way for patients to get prescriptions at lower, PBM-negotiated prices even if they have yet to satisfy an annual insurance deductible or they have no insurance at all. In general, coupon-generating websites/apps offer consumers access to the deeper pharmacy benefits manager ( " PBM " )-negotiated prices on prescription drugs, at prices which are often substantially less than the prices you could otherwise attain as a consumer without the benefit of a commercial healthcare...
Source: Scott's Web Log - September 1, 2021 Category: Endocrinology Tags: CGM CGMS coupon-generating websites apps Dexcom insulin Libre PBM test strips Source Type: blogs
Prostacyclins and pulmonary arterial hypertension in children
CONCLUSIONS: Epoprostenol can be effective against severe pulmonary hypertension. Iloprost can treat severe persistent pulmonary hypertension in newborns and inhaled iloprost can be used in pulmonary vasoreactivity testing. Treprostinil is a long-acting prostacyclin analog, and it shows the highest antiproliferative activity among prostacyclins. Beraprost may be effective in premature infants, but available evidence comes from only one patient, so more clinical testing is needed.PMID:35049017 | DOI:10.26355/eurrev_202201_27745
Source: Pharmacological Reviews - January 20, 2022 Category: Drugs & Pharmacology Authors: Y Wu H-M Liu L Gu Q-W Li L Zhu Source Type: research
Interventions for focal segmental glomerulosclerosis in adults
CONCLUSIONS: No RCTs, which evaluated corticosteroids, were identified although the KDIGO guidelines recommend corticosteroids as the first treatment for adults with FSGS. The studies identified included participants with steroid-resistant FSGS. Treatment with cyclosporin for at least six months was more likely to achieve complete remission of proteinuria compared with other treatments but there was considerable imprecision due to few studies and small participant numbers. In future studies of existing or new interventions, the investigators must clearly define the populations included in the study to provide appropriate r...
Source: Cochrane Database of Systematic Reviews - February 28, 2022 Category: General Medicine Authors: Elisabeth M Hodson Aditi Sinha Tess E Cooper Source Type: research
Interventions for minimal change disease in adults with nephrotic syndrome
CONCLUSIONS: This updated review has identified evidence for the efficacy and adverse effects of CNIs and EC-MPS with or without reduced-dose prednisolone compared with prednisolone alone for the induction of remission in adults with MCD and nephrotic syndrome with some reductions in steroid-associated adverse events. RCT data on the efficacy and adverse effects of rituximab in adults with MCD are awaited. Further, adequately powered RCTs are required to determine the relative efficacies of CNIs and EC-MPS and to evaluate these medications in patients with relapsing or steroid-resistant disease.PMID:35230699 | DOI:10.1002/...
Source: Cochrane Database of Systematic Reviews - March 1, 2022 Category: General Medicine Authors: Karolis Azukaitis Suetonia C Palmer Giovanni Fm Strippoli Elisabeth M Hodson Source Type: research
Interventions for focal segmental glomerulosclerosis in adults
CONCLUSIONS: No RCTs, which evaluated corticosteroids, were identified although the KDIGO guidelines recommend corticosteroids as the first treatment for adults with FSGS. The studies identified included participants with steroid-resistant FSGS. Treatment with cyclosporin for at least six months was more likely to achieve complete remission of proteinuria compared with other treatments but there was considerable imprecision due to few studies and small participant numbers. In future studies of existing or new interventions, the investigators must clearly define the populations included in the study to provide appropriate r...
Source: Cochrane Database of Systematic Reviews - February 28, 2022 Category: General Medicine Authors: Elisabeth M Hodson Aditi Sinha Tess E Cooper Source Type: research
Management of hypertension and dyslipidemia in Mexico: Evidence, gaps, and approach
Arch Cardiol Mex. 2022 Mar 31. doi: 10.24875/ACM.21000330. Online ahead of print.ABSTRACTHypertension and dyslipidemia are key risk factors for cardiovascular disorders and mortality worldwide. To understand the local health system challenges faced in the management of the two conditions, a semi-systematic approach was adopted for quantifying stages of the journey of care of adult Mexican patients, namely, awareness, screening, diagnosis, treatment, adherence, and control. A structured literature search was conducted for articles published in English from 2010 to 2019 in EMBASE and MEDLINE databases. The articles restricte...
Source: Archivos de Cardiologia de Mexico - March 31, 2022 Category: Cardiology Authors: Enrique C Morales-Villegas Carlos Yarleque Mar ía L Almeida Source Type: research
Turning PBM " Arbitrage " On Its Head: Bypassing Insurance to Save
The word of the day is " arbitrage " . Officially, Merriam-Webster defines the English language word " arbitrage " this way: " The nearly simultaneous purchase and sale of securities or foreign exchange in different markets in order to profit from price discrepancies " . However, arbitrage does not exclusively apply to securities sold on Wall Street. The term has also been adopted by the Pharmacy Benefit Manager ( " PBM " ) industry. But PBM ' s are not Wall Street investment banks. And that ' s something we all need to realize.The PBM Accountability Project 2021 report " Understanding the Evolving Business Model...
Source: Scott's Web Log - July 25, 2022 Category: Endocrinology Tags: 2022 arbitrage coupon-generating websites apps coupons Medicare PBM Source Type: blogs
