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Total 333 results found since Jan 2013.

Telephone-based cognitive-behavioural therapy and a structured exercise programme are effective for chronic widespread pain (fibromyalgia)
Commentary on: McBeth J, Prescott G, Scotland G, et al.. Cognitive behavior therapy, exercise, or both for treating chronic widespread pain. Arch Intern Med 2012;172:48–57. Context Chronic widespread pain (CWP) is the cardinal feature of fibromyalgia which is one of the three most common musculoskeletal disorders in clinical practice, the others being osteoarthritis and chronic low back pain. CWP is disabling as well as costly and difficult to treat. Methods In a 2x2 factorial randomised controlled trial, 442 patients with CWP were randomised to receive 6 months of telephone-delivered cognitive-behavioural therapy (T...
Source: Evidence-Based Medicine - January 17, 2013 Category: Internal Medicine Authors: Kroenke, K. Tags: Patients, Clinical trials (epidemiology), Neuromuscular disease, Pain (neurology), Psychotherapy, Degenerative joint disease, Fibromyalgia, Musculoskeletal syndromes, Osteoarthritis Therapeutics Source Type: research

(208) Catastrophizing cognitions promote proinflammatory cytokine responses to acute pain in fibromyalgia
For patients that suffer from musculoskeletal pain conditions such as fibromyalgia and osteoarthritis, catastrophizing plays an important role in shaping the pain experience. The mechanisms that underlie catastrophizing’s effects are multifactorial, and some research has reported that high levels of catastrophizing are associated with enhanced physiological reactivity to painful stimulation. In the present study we investigated the association between catastrophizing and inflammatory pain responses (i.e., increases in IL-6 during experimental pain testing) in several groups.
Source: The Journal of Pain - March 27, 2015 Category: Materials Science Authors: O. Franceschelli, C. Cahalan, M. Martel, R. Edwards Tags: B04 Fibromyalgia Source Type: research

Differential Neuroplastic Changes in Fibromyalgia and Depression Indexed by Up-Regulation of Motor Cortex Inhibition and Disinhibition of the Descending Pain System: An Exploratory Study
Conclusion: These findings support the hypothesis that in FM a deteriorated function of cortical inhibition, indexed by a higher SICI parameter, a lower function of the DPMS, together with a higher level of BDNF indicate that FM has different pathological substrates from depression. They suggest that an up-regulation phenomenon of intracortical inhibitory networks associated with a disruption of the DPMS function occurs in FM. Introduction Major depressive disorder (MDD) and fibromyalgia (FM) present overlapped symptoms. Although the connection between these two disorders has not been elucidated yet, the disruption...
Source: Frontiers in Human Neuroscience - April 24, 2019 Category: Neuroscience Source Type: research

Comparison of sleep structure and psychometric profiles in patients with fibromyalgia, osteoarthritis and healthy controls.
Abstract While research indicates that both the macro- and microstructure of sleep may be altered in fibromyalgia syndrome, few studies have controlled for symptom duration or included pain-control participants (i.e. patients with chronic pain and sleep disturbance not associated with fibromyalgia syndrome). A frequently reported alteration found in the sleep microstructure of patients with fibromyalgia syndrome is the alpha-delta sleep anomaly. Although alpha waves have been observed during N3 sleep in healthy individuals, it has been proposed that there is an increase in alpha wave activity during slow-wave slee...
Source: Journal of Sleep Research - August 11, 2017 Category: Sleep Medicine Authors: Yeung WK, Morgan K, Mckenna F Tags: J Sleep Res Source Type: research

Comparison of sleep structure and psychometric profiles in patients with fibromyalgia, osteoarthritis and healthy controls
Summary While research indicates that both the macro‐ and microstructure of sleep may be altered in fibromyalgia syndrome, few studies have controlled for symptom duration or included pain‐control participants (i.e. patients with chronic pain and sleep disturbance not associated with fibromyalgia syndrome). A frequently reported alteration found in the sleep microstructure of patients with fibromyalgia syndrome is the alpha‐delta sleep anomaly. Although alpha waves have been observed during N3 sleep in healthy individuals, it has been proposed that there is an increase in alpha wave activity during slow‐wave sleep ...
Source: Journal of Sleep Research - August 1, 2017 Category: Neurology Authors: Wai K. Yeung, Kevin Morgan, Frank Mckenna Tags: Regular Research Paper Source Type: research

Social security work disability and its predictors in patients with fibromyalgia
Conclusions. The prevalence of SSD is high in fibromyalgia, but not higher than in RA and OA patients who satisfy fibromyalgia criteria. The best predictors of work disability are functional status variables. © 2014 American College of Rheumatology.
Source: Arthritis Care and Research - February 10, 2014 Category: Rheumatology Authors: Frederick Wolfe, Brian T. Walitt, Robert S. Katz, Winfried Häuser Tags: Original Article Source Type: research

Treatment of Fibromyalgia in the 21st Century
To the Editor The thorough, systematic review of therapies for fibromyalgia written by Mascarenhas et al concludes that antidepressants and central nervous system depressants are effective treatments for this condition, but the effect sizes are small and fail to reach the threshold for clinical importance. While their findings are congruent with clinical trials, their discussion assumes that most patients with fibromyalgia are treated with a single modality at a time (pharmacologic or otherwise); however, the current standard of care for fibromyalgia and other chronic pain conditions is to use a stepped care model where mu...
Source: JAMA Internal Medicine - March 8, 2021 Category: Internal Medicine Source Type: research

Guidelines for the successful management of fibromyalgia patients
Publication date: December 2014 Source:Indian Journal of Rheumatology, Volume 9, Supplement 2 Author(s): Robert M. Bennett The successful management of fibromyalgia starts with establishing a firm diagnosis, followed by an evaluation of all other comorbid pain conditions (e.g. osteoarthritis, temporomandibular pain disorder, migraine headaches, myofascial trigger points) and fibromyalgia associated comorbidities (e.g. restless leg syndrome, irritable bowel syndrome). Then, it is necessary to systematically go through a list of problems that need to be addressed: pain, sleep, fatigue, mood disorders, cognitive dysfunction...
Source: Indian Journal of Rheumatology - November 19, 2014 Category: Rheumatology Source Type: research

Validation of the Spanish version of the fibromyalgia rapid screening tool to detect fibromyalgia in primary care health centres.
CONCLUSIONS: FiRST questionnaire is a useful tool for the detection of FM in primary care health centres. PMID: 27055283 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - April 9, 2016 Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research

Design and validation of a predictive model for determining the risk of developing fibromyalgia
CONCLUSIONS: The proposed model showed an excellent predictive capacity. The risk calculator designed from the predictive model allows health professionals to have a useful tool to identify subjects at risk of developing fibromyalgia.PMID:36622095 | DOI:10.55563/clinexprheumatol/r23r95
Source: Clinical and Experimental Rheumatology - January 9, 2023 Category: Rheumatology Authors: Narly Benachi Sandoval Joaquim R Fern ández Solà Andrea Guaita Mateo M Pilar Navarrete Dur án Luz A Meneses Urrea Susanna Torres Belmonte Elena Ma ñes López Mireia L ópez Poyato Source Type: research