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Total 779 results found since Jan 2013.

The Prevalence of Fibromyalgia in the General Population: A Comparison of the American College of Rheumatology 1990, 2010, and Modified 2010 Classification Criteria
ConclusionFibromyalgia prevalence varies with the different sets of classification criteria applied. In particular, prevalence is higher and a greater proportion of men are identified with the modified 2010 criteria as compared to the criteria sets requiring clinician input. This has important implications for the use of the new criteria, both in research and in clinical practice.
Source: Arthritis and Rheumatism - January 28, 2015 Category: Rheumatology Authors: Gareth T. Jones, Fabiola Atzeni, Marcus Beasley, Elisa Flüß, Piercarlo Sarzi‐Puttini, Gary J. Macfarlane Tags: Fibromyalgia Source Type: research

Clinical Characteristics and Medication Uses Among Fibromyalgia Patients Newly Prescribed Amitriptyline, Duloxetine, Gabapentin, or Pregabalin
ConclusionPatients who started 1 of the 4 common drugs for fibromyalgia similarly had multiple comorbidities and other fibromyalgia‐related medication use, but continued the treatment only for a short time. The dose of the 4 drugs was not increased in most patients during the followup period.
Source: Arthritis Care and Research - October 28, 2013 Category: Rheumatology Authors: Seoyoung C. Kim, Joan E. Landon, Daniel H. Solomon Tags: Fibromyalgia Source Type: research

Telephone-based cognitive-behavioural therapy and a structured exercise programme are effective for chronic widespread pain (fibromyalgia)
Commentary on: McBeth J, Prescott G, Scotland G, et al.. Cognitive behavior therapy, exercise, or both for treating chronic widespread pain. Arch Intern Med 2012;172:48–57. Context Chronic widespread pain (CWP) is the cardinal feature of fibromyalgia which is one of the three most common musculoskeletal disorders in clinical practice, the others being osteoarthritis and chronic low back pain. CWP is disabling as well as costly and difficult to treat. Methods In a 2x2 factorial randomised controlled trial, 442 patients with CWP were randomised to receive 6 months of telephone-delivered cognitive-behavioural therapy (T...
Source: Evidence-Based Medicine - January 17, 2013 Category: Internal Medicine Authors: Kroenke, K. Tags: Patients, Clinical trials (epidemiology), Neuromuscular disease, Pain (neurology), Psychotherapy, Degenerative joint disease, Fibromyalgia, Musculoskeletal syndromes, Osteoarthritis Therapeutics Source Type: research

Chronic widespread pain and the fibromyalgia syndrome
Chronic pain syndromes are characterized by pain that is present every day and is not explicable by any specific physical injury or disease. The pain is related to central sensitization of the central nervous system pain mechanisms such that pain is amplified. The term ‘chronic widespread pain’ (CWP) means that the pain is present on both sides of the body, both above and below the waist and in the spinal region. Fibromyalgia is a subgroup of CWP in which, as well as pain, patients suffer from typical symptoms including fatigue, unrefreshing sleep and ‘fibro -fog’.
Source: Medicine - February 3, 2022 Category: Internal Medicine Authors: Anisur Rahman Tags: Fibromyalgia and chronic pain syndrome Source Type: research

Differential Neuroplastic Changes in Fibromyalgia and Depression Indexed by Up-Regulation of Motor Cortex Inhibition and Disinhibition of the Descending Pain System: An Exploratory Study
Conclusion: These findings support the hypothesis that in FM a deteriorated function of cortical inhibition, indexed by a higher SICI parameter, a lower function of the DPMS, together with a higher level of BDNF indicate that FM has different pathological substrates from depression. They suggest that an up-regulation phenomenon of intracortical inhibitory networks associated with a disruption of the DPMS function occurs in FM. Introduction Major depressive disorder (MDD) and fibromyalgia (FM) present overlapped symptoms. Although the connection between these two disorders has not been elucidated yet, the disruption...
Source: Frontiers in Human Neuroscience - April 24, 2019 Category: Neuroscience Source Type: research

The prevalence and clinical features of fibromyalgia in Chinese hospital  patients with primary headache: The survey of fibromyalgia comorbid with headache
CONCLUSIONS: The prevalence of fibromyalgia in mainland Chinese patients with primary headache was 6.0%. Fibromyalgia was more common in those with chronic rather than episodic headache. The most common sites of fibromyalgia pain were the neck, shoulders, and back.PMID:36651491 | DOI:10.1111/head.14443
Source: Headache - January 18, 2023 Category: Neurology Authors: Zhao Dong Kaiming Liu Huanxian Liu Zhihua Jia Wei Gui Ming Dong Yingying Cheng Yudan Lv Kang Qu Hongru Zhao Jianjun Chen Dan Zhang Zhiliang Fan Xiaosu Yang Dongmei Hu Yanbo Zhang Hongyan Xie Mingxin Li Bing Wen Sufen Chen Peng Xu Qingqing Rong Qiu He Zhan Source Type: research

Should a Coexisting or Suspected Diagnosis of Fibromyalgia Affect the Decision to Perform Diagnostic Blocks for Patients with Chronic Noncancer Pain - Results from an Observational Research Study
CONCLUSION: We conclude that after physician selection, the presence of fibromyalgia phenotype does not influence the outcome from diagnostic block. It is likely therefore that fibromyalgia phenotype should not influence the decision to perform diagnostic blocks if indicated based on assessment by an experienced pain physician.PMID:33740354
Source: Pain Physician - March 19, 2021 Category: Anesthesiology Authors: Tomasz Bendinger Joel Stephen Perfitt Source Type: research

Aberrant Analgesic Response to Medial Branch Blocks in Patients With Characteristics of Fibromyalgia
Conclusions: Characteristics of fibromyalgia may indicate pain that is more centralized in nature, a factor that may explain the aberrant analgesic response to this peripheral intervention. This may have implications for future prediction of treatment response, although prospective studies are needed.
Source: Regional Anesthesia and Pain Medicine - April 24, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Dorsal root ganglia: fibromyalgia pain factory?
AbstractThisperspective article focuses on dorsal root ganglia (DRG) as potential fibromyalgia main pain source. Humans possess 31 pairs of DRG lying along the spine. These ganglia have unique anatomical and physiological features. During development, DRG are extruded from the central nervous system and from the blood-brain barrier but remain surrounded by meningeal layers and by cerebrospinal fluid. DRG house the pain-transmitting small nerve fiber nuclei; each individual nucleus is tightly enveloped by metabolically active glial cells. DRG possess multiple inflammatory/pro-nociceptive molecules including ion channels, ne...
Source: Clinical Rheumatology - January 6, 2021 Category: Rheumatology Source Type: research

Association of antithyroid peroxidase antibody with fibromyalgia in rheumatoid arthritis
Abstract To investigate how autoimmune thyroiditis (ATD) affects the clinical presentation of established rheumatoid arthritis (RA) with particular reference to fibromyalgia and chronic widespread pain (CWP). A cohort of 204 patients with RA for whom the presence or absence of autoimmune thyroid antibodies was documented was examined for the relationships between thyroid autoantibodies and fibromyalgia or CWP. We identified 29 % who tested positive for antithyroid peroxidase antibodies (TPOAb). The anti-thyroglobulin antibody (TgAb) was found in 24 %. Among the thyroid autoantibody-positive patients, 40 % had a...
Source: Rheumatology International - May 15, 2015 Category: Rheumatology Source Type: research

Altered Cervical Spinal Cord Resting ‐State Activity in Fibromyalgia
ConclusionOur results indicate unbalanced activity between the ventral and dorsal cervical spinal cord in fibromyalgia. Increased ventral neural processes and decreased dorsal neural processes may reflect the presence of central sensitization and contribute to fatigue and other bodily symptoms in fibromyalgia.
Source: Arthritis and Rheumatology - February 11, 2019 Category: Rheumatology Authors: Katherine T. Martucci, Kenneth A. Weber, Sean C. Mackey Tags: Original Article Source Type: research