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Condition: Pregnancy
Infectious Disease: Hepatitis B
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Total 299 results found since Jan 2013.
Viral Hepatitis in Pregnancy: ACOG Clinical Practice Guideline No. 6
Obstet Gynecol. 2023 Sep 1;142(3):745-759. doi: 10.1097/AOG.0000000000005300.ABSTRACTPURPOSE: The purpose of this document is to describe the specific types of viral hepatitis, their implications during pregnancy, the risk of perinatal transmission, and issues related to both treatment and prevention of infection.TARGET POPULATION: Pregnant or postpartum women and individuals who screen positive for viral hepatitis infection. The onset of these conditions may have predated the perinatal period or may have occurred for the first time in pregnancy or the first year postpartum.METHODS: This guideline was developed using an a ...
Source: Obstetrics and Gynecology - August 17, 2023 Category: OBGYN Source Type: research
Comparison of Antiretroviral Therapies in Pregnant Women Living With Human Immunodeficiency Virus and Hepatitis B Virus: A Randomized Controlled Trial
CONCLUSION: Over a short period of time, HBV DNA suppression was not different with one or two HBV-active agents. HbeAg loss occurred in a substantial proportion of participants. Perinatal transmission of HBV infection was low. Hepatitis B virus-active ART was well-tolerated in pregnancy, with few grade 3 or 4 ALT or AST elevations.CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov, NCT01061151.PMID:37535953 | DOI:10.1097/AOG.0000000000005302
Source: Obstetrics and Gynecology - August 3, 2023 Category: OBGYN Authors: Debika Bhattacharya Camlin Tierney Kevin Butler Flavia Matovu Kiweewa Dhayendre Moodley Vani Govender Tichaona Vhembo Neaka Mohtashemi Hannah Ship Dingase Dula Kathy George Nahida Chaktoura Mary Glenn Fowler Marion G Peters Judith S Currier Source Type: research
Analysis of hepatocellular carcinoma associated with hepatitis B virus
J Cell Mol Med. 2023 Jul 30. doi: 10.1111/jcmm.17867. Online ahead of print.ABSTRACTThe hepatitis B virus (HBV) is considered one of the main driving forces in the development of hepatocellular carcinoma (HCC). Human HBV is a partially double-stranded DNA (dsDNA) virus consisting of approximately 3.2 kbp. HBV predominantly infects hepatocytes via the receptor sodium taurocholate cotransporting polypeptide (NTCP) and coreceptor hepatic proteoglycan. The replication of HBV in hepatocytes leads to apoptosis while simultaneously leading to cirrhosis and cancer. Although the integration of dsDNA into the hepatocyte genome seems...
Source: J Cell Mol Med - July 30, 2023 Category: Molecular Biology Authors: Litao Zheng Source Type: research
Estimates of hepatitis B virus prevalence among general population and key risk groups in EU/EEA/UK countries: a systematic review
ConclusionsThe HBV prevalence is low in the general population and confined to risk populations in most European countries with some exceptions. Screening and treatment should be targeted to people in prison and migrants.PMID:37498533 | PMC:PMC10375838 | DOI:10.2807/1560-7917.ES.2023.28.30.2200738
Source: Euro Surveill - July 27, 2023 Category: Infectious Diseases Authors: Sandra Bivegete Anna L McNaughton Adam Trickey Zak Thornton Becky Scanlan Aaron G Lim Lina Nerlander Hannah Fraser Josephine G Walker Matthew Hickman Peter Vickerman Helen Johnson Erika Duffell Ellen Brooks-Pollock Hannah Christensen Source Type: research
