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Total 68124 results found since Jan 2013.

A tale of two arteries: dual posterior cerebral arteries with vascular bridges. A possible protective pattern?
Authors: Mansour Y, Kulesza R Abstract Stroke is a common morbidity and a frequent cause of disability and even death. The impact of cerebrovascular events are dictated by the brain region involved and can be complicated by anatomical variations. One of the most common variations impacting the cerebrovasculature is the presence of a fetal posterior cerebral artery. This vessel arises from the internal carotid artery instead of the basilar artery and is often associated with more extensive injury in cerebrovascular events. Herein, we report the case of a 60-year-old male who had numerous arterial abnormalities, incl...
Source: Folia Morphologica - July 10, 2020 Category: Anatomy Tags: Folia Morphol (Warsz) Source Type: research

Sleep, brain vascular health and ageing
AbstractSleep maintains the function of the entire body through homeostasis. Chronic sleep deprivation (CSD) is a prime health concern in the modern world. Previous reports have shown that CSD has profound negative effects on brain vasculature at both the cellular and molecular levels, and that this is a major cause of cognitive dysfunction and early vascular ageing. However, correlations among sleep deprivation (SD), brain vascular changes and ageing have barely been looked into. This review attempts to correlate the alterations in the levels of major neurotransmitters (acetylcholine, adrenaline, GABA and glutamate) and s...
Source: AGE - August 2, 2020 Category: Geriatrics Source Type: research

Robot-assisted transthoracic first rib resection for venous thoracic outlet syndrome
CONCLUSION: Robot-assisted transthoracic first rib resection with only three trocars is a feasible minimal invasive approach for first rib resection in the management of vTOS. This technique enables the surgeon to perform venolysis under direct 3D vision with good patency and long-term functional outcome. Studies with larger cohort size are needed to compare the outcomes of this robot-assisted technique with other more established approaches.PMID:33832359 | DOI:10.1177/1708538121997332
Source: Vascular - April 9, 2021 Category: Surgery Authors: Frank Hoexum Vincent Jongkind Hans Me Coveliers Kak K Yeung Willem Wisselink Source Type: research

Patients with Congenital Low-Flow Vascular Malformation Treated with Low Dose Sirolimus
ConclusionsLow dose sirolimus showed a high efficacy in patients with therapy-resistant and low-flow malformation, with a lower incidence of serious adverse events. At the same time a new adverse event, namely menstrual cycle disturbance, was observed in young adolescents, indicating the need for caution when sirolimus is given. This is extremely relevant to patients with low-flow vascular malformation, who are likely to require lifelong treatment for their condition.
Source: Advances in Therapy - May 18, 2021 Category: Drugs & Pharmacology Source Type: research

Adipose tissue-derived stromal vascular fraction for treating hands of patients with systemic sclerosis: a multicentre randomized trial
CONCLUSION: This study showed an improvement of hand function in both groups other time, with no superiority of the AD-SVF. Considering the limits of this trial, studies on a larger population of patients with homogeneous phenotype and hand handicap, should be encouraged to accurately assess the benefit of AD-SVF therapy.TRIAL REGISTRATION: ClinicalTrials.gov, https://clinicaltrials.gov, NCT02558543. Registered on September 24, 2015.PMID:34297066 | DOI:10.1093/rheumatology/keab584
Source: Pain Physician - July 23, 2021 Category: Anesthesiology Authors: Aur élie Daumas J érémy Magalon Elisabeth Jouve Dominique Casanova C écile Philandrianos Maxime Abellan Lopez St éphanie Mallet Julie Veran Isabelle Auquit-Auckbur Dominique Farge Herv é Levesque Ygal Benhamou Laurent Arnaud Laurent Giraudo Chlo é Source Type: research

Injectable hydrogels for vascular embolization and cell delivery: The potential for advances in cerebral aneurysm treatment
Biomaterials. 2021 Aug 31;277:121109. doi: 10.1016/j.biomaterials.2021.121109. Online ahead of print.ABSTRACTCerebral aneurysms are vascular lesions caused by the biomechanical failure of the vessel wall due to hemodynamic stress and inflammation. Aneurysmal rupture results in subarachnoid hemorrhage often leading to death or disability. Current treatment options include open surgery and minimally invasive endovascular options aimed at secluding the aneurysm from the circulation. Cerebral aneurysm embolization with appropriate materials is a therapeutic approach to prevent rupture and the resultant clinical sequelae. Metal...
Source: Biomaterials - September 16, 2021 Category: Materials Science Authors: Seungil Kim Kamil W Nowicki Bradley A Gross William R Wagner Source Type: research

Utility and reliability of the Clinical Frailty Scale in patients scheduled for major vascular surgery: a prospective, observational, multicentre observer-blinded study
ConclusionsThe Clinical Frailty Scale is a useful tool to assess frailty in the vascular surgical population. It is more practical than the Edmonton Frailty Scale: quick to complete, requires minimal training and can be used when physical disability is present.Trial registrationThe study was approved by the Wales Health and Care Research Ethics Service (REC reference 17/WA/0160, IRAS 201173). Trial registration: NCT03403673. Registered 19 January 2018,https://clinicaltrials.gov/ct2/show/NCT03403673
Source: Perioperative Medicine - January 31, 2022 Category: Surgery Source Type: research

Communication with parents and young adult patients affected by complex vascular malformations
CONCLUSION: Interviews with parents and young adult patients with VMs provided evidence for eight functions of communication. While exchanging information and building relationships were described by nearly every respondent, supporting hope and responding to emotions were mentioned less frequently. Future studies should develop patient-reported communication measures to quantify the fulfillment of these functions and to identify areas of communication in need of intervention.PMID:36545911 | DOI:10.1002/pbc.30158
Source: Pain Physician - December 22, 2022 Category: Anesthesiology Authors: Bryan Sisk Christine Bereitschaft Anna Kerr Source Type: research

Transcription factors: key regulatory targets of vascular smooth muscle cell in atherosclerosis
Mol Med. 2023 Jan 5;29(1):2. doi: 10.1186/s10020-022-00586-2.ABSTRACTAtherosclerosis (AS), leading to gradual occlusion of the arterial lumen, refers to the accumulation of lipids and inflammatory debris in the arterial wall. Despite therapeutic advances over past decades including intervention or surgery, atherosclerosis is still the most common cause of cardiovascular diseases and the main mechanism of death and disability worldwide. Vascular smooth muscle cells (VSMCs) play an imperative role in the occurrence of atherosclerosis and throughout the whole stages. In the past, there was a lack of comprehensive understandin...
Source: Atherosclerosis - January 5, 2023 Category: Cardiology Authors: Yu Jiang Hai-Yan Qian Source Type: research

Decline in Vascular Function Correlates with Decline in Physical Function
The vasculature becomes increasingly dysfunctional with age in a number of different ways, from loss of capillary density to tissue stiffening and issues with smooth muscle function that lead to raised blood pressure, as well as the development of endothelial inflammation and atherosclerotic lesions that lead to heart attack or stroke. It isn't surprising to find that even simple measures of vascular aging, such as raised blood pressure, correlate fairly well with other aspects of aging, such as declines in physical function. Approximately 10% of older adults have muscle weakness and diminished physical function t...
Source: Fight Aging! - May 22, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Palmoplantar contractures in childhood: a rare complication of vascular Ehlers–Danlos syndrome
We report a young man with vascular EDS, who developed flexion contractures and tendon nodules, causing considerable disability. Limited management strategies are available for these complications, which have continued to prove a challenge to management.
Source: Clinical And Experimental Dermatology - May 15, 2013 Category: Dermatology Authors: A. C. Foulkes, R. Pollitt, G. Sobey, F. M. Pope, A. E. M. Taylor Tags: Clinical Dermatology ● Concise Report Source Type: research