Filtered By:
Drug: Tetracycline

This page shows you your search results in order of relevance.

Order by Relevance | Date

Total 6029 results found since Jan 2013.

Obesity and Overweight are Highly Prevalent in Pediatric Secondary Pseudotumor Cerebri Syndrome (P5.304)
CONCLUSIONS: Pediatric patients diagnosed with secondary PTCS were on average significantly overweight compared to their peers. Hence excess body weight may contribute to PTCS even when a potential secondary cause is identified. Study Supported by:5-K12-DK-94723-2(SEM)Disclosure: Dr. Paley has nothing to disclose. Dr. Sheldon has nothing to disclose. Dr. Burrows has nothing to disclose. Dr. Chilutti has nothing to disclose. Dr. Liu has received personal compensation for activities with Ipsen as a consultant. Dr. McCormack has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Paley, G., Sheldon, C., Burrows, E., Chilutti, M., Liu, G., McCormack, S. Tags: Neuro-ophthalmology/Neuro-otology II Source Type: research

Neuroprotective and Neuro-restorative Effects of Minocycline and Rasagiline in a Zebrafish 6-Hydroxydopamine Model of Parkinson ’s Disease
We describe a 6-hydroxydopamine (6-OHDA) zebrafish model to screen drugs for neuroprotective and neuro-restorative capacity. Zebrafish larvae at two days post fertilization were exposed to 6-OHDA for three days, with co-administration of test drugs for neuroprotection experiments, or for 32 h, with subsequent treatment with test drugs for neuro-restoration experiments. Locomotor activity was assessed by automated tracking and dopaminergic neurons were visualized by tyrosine hydroxylase immuno-histochemistry. Exposure to 6-OHDA for either 32 h or 3 days induced similar, significant locomotor deficits and neuronal loss...
Source: Neuroscience - November 8, 2017 Category: Neuroscience Source Type: research

Attenuation of neuro-inflammation improves survival and neurodegeneration in a mouse model of severe neonatal hyperbilirubinemia.
Abstract All pre-term newborns and a high proportion of term newborns develop neonatal jaundice. Neonatal jaundice is usually a benign condition and self-resolves within few days after birth. However, a combination of unfavorable complications may lead to acute hyperbilirubinemia. Excessive hyperbilirubinemia may be toxic for the developing nervous system leading to severe neurological damage and death by kernicterus. Survivors show irreversible neurological deficits such as motor, sensitive and cognitive abnormalities. Current therapies rely on the use of phototherapy and, in unresponsive cases, exchange transfus...
Source: Brain, Behavior, and Immunity - February 16, 2018 Category: Neurology Authors: Vodret S, Bortolussi G, Iaconcig A, Martinelli E, Tiribelli C, Muro AF Tags: Brain Behav Immun Source Type: research

Attenuation of neuro-inflammation improves survival and neurodegeneration in a mouse model of severe neonatal hyperbilirubinemia
Publication date: Available online 16 February 2018 Source:Brain, Behavior, and Immunity Author(s): Simone Vodret, Giulia Bortolussi, Alessandra Iaconcig, Elena Martinelli, Claudio Tiribelli, Andrés F. Muro All pre-term newborns and a high proportion of term newborns develop neonatal jaundice. Neonatal jaundice is usually a benign condition and self-resolves within few days after birth. However, a combination of unfavorable complications may lead to acute hyperbilirubinemia. Excessive hyperbilirubinemia may be toxic for the developing nervous system leading to severe neurological damage and death by kernicterus. Survivor...
Source: Brain, Behavior, and Immunity - February 17, 2018 Category: Neurology Source Type: research

Ecotoxicity of selected antibiotics for organisms of aquatic and terrestrial ecosystems.
CONCLUSION: The ecotoxicity of antibiotics differed significantly depending on the test organism and testing conditions. PMID: 28263529 [PubMed - as supplied by publisher]
Source: Neuroendocrinology Letters - March 8, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Minocycline reduces inflammatory parameters in the brain structures and serum and reverses memory impairment caused by the administration of amyloid β (1-42) in mice
Publication date: Available online 21 March 2017 Source:Progress in Neuro-Psychopharmacology and Biological Psychiatry Author(s): Michelle Lima Garcez, Francielle Mina, Tatiani Bellettini-Santos, Franciellen Gonçalves Carneiro, Aline Pereira da Luz, Gustavo Luis Schiavo, Matheus Scopel Andrighetti, Maylton Grégori Scheid, Renan Pereira Bolfe, Josiane Budni Alzheimer's disease (AD) is a neurodegenerative disorder and the most common type of age-related dementia. Cognitive decline, beta-amyloid (Aβ) accumulation, neurofibrillary tangles, and neuroinflammation are the main pathophysiological characteristics of AD. Minocyc...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - March 20, 2017 Category: Psychiatry Source Type: research

Minocycline adjunctive treatment to risperidone for negative symptoms in schizophrenia: Association with pro-inflammatory cytokine levels
Conclusions Schizophrenia patients showed a significant improvement in negative symptoms with the addition of minocycline to risperidone. Reducing pro-inflammatory cytokines may play an important role in the potential mechanism for efficacy.
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - April 24, 2018 Category: Psychiatry Source Type: research

Aedes –Chikungunya Virus Interaction: Key Role of Vector Midguts Microbiota and Its Saliva in the Host Infection
Conclusion and Perspectives Arbovirus infections, such as CHIKV, have been growing worldwide and are becoming a major public health problem, especially in immuno-compromised classes such as children and the elderly. CHIKV is dangerous since it can cause arthritis, fever and other impairments, making it necessary to seek new ways to counter the proliferation of this virus. Knowing the vector’s competence is fundamentally important, including an understanding of the vector virus interaction and the modulation of this interaction. Despite advances in the knowledge of mosquito competence in the transmission of CHIKV, l...
Source: Frontiers in Microbiology - April 8, 2019 Category: Microbiology Source Type: research

Validation of a 16th Century Traditional Chinese Medicine Use of Ginkgo biloba as a Topical Antimicrobial
This study aimed to examine the traditional use of Ginkgo seeds as topical treatment for skin disorders for potential antibacterial efficacy. This is the first study to test and compare the antibacterial activity of various Ginkgo seed extracts on skin pathogens. In this work, we confirmed the ethnomedicinal importance of seeds in the treatment of skin diseases. As reported in the Compendium of Materia Medica Ben Cao Gang Mu, only the seeds were used for medicinal uses, especially as a topical treatment for skin infections. Moreover, our study validates the antimicrobial activity of the seed (i.e., seed coats and immature...
Source: Frontiers in Microbiology - April 15, 2019 Category: Microbiology Source Type: research

Interventions for managing medication-related osteonecrosis of the jaw
CONCLUSIONS: Prophylaxis of medication-related osteonecrosis of the jaw One open-label RCT provided some evidence that dental examinations at three-month intervals and preventive treatments may be more effective than standard care for reducing the incidence of medication-related osteonecrosis of the jaw (MRONJ) in individuals taking intravenous bisphosphonates for advanced cancer. We assessed the certainty of the evidence to be very low. There is insufficient evidence to either claim or refute a benefit of the interventions tested for prophylaxis of MRONJ in patients with antiresorptive therapy undergoing dentoalveolar sur...
Source: Cochrane Database of Systematic Reviews - July 22, 2022 Category: General Medicine Authors: Natalie H Beth-Tasdogan Benjamin Mayer Heba Hussein Oliver Zolk Jens-Uwe Peter Source Type: research