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Fractional exhaled nitric oxide and asthma treatment adherence
Purpose of review Despite increased clinician awareness, nonadherence to inhaled corticosteroid treatment presents a major challenge to successful asthma management and risks inappropriate treatment escalation, particularly in severe disease. In patients with Type-2 mediated biology, fractional exhaled nitric oxide (FeNO) has a role in assessment and monitoring of adherence to inhaled corticosteroids. Recent findings Asthmatic patients with elevated FeNO are at an increased risk of exacerbation. High FeNO is often secondary to suboptimal adherence to inhaled corticosteroid treatment, whether intentional or nonin...
Source: Current Opinion in Allergy and Clinical Immunology - December 26, 2020 Category: Allergy & Immunology Tags: MECHANISMS OF ALLERGY AND ADULT ASTHMA: Edited by J. Andrew Grant and Enrico Heffler Source Type: research

Exploring the origin and regulatory role of mast cells in asthma
Purpose of review Mast cells have previously been thought to function solely as effector cells in asthma but more recent studies have indicated that mast cells may play a more central role in propagating and regulating lower airway inflammation in asthma. Recent findings Initial studies have found increased numbers of mast cell progenitors (MCPs) in the peripheral blood of patients with asthma and these cells could contribute to the increased number of progenitors identified in the airways of patients with asthma. There are unique subpopulations of mast cells within the asthmatic airway, which are characterized ...
Source: Current Opinion in Allergy and Clinical Immunology - December 26, 2020 Category: Allergy & Immunology Tags: MECHANISMS OF ALLERGY AND ADULT ASTHMA: Edited by J. Andrew Grant and Enrico Heffler Source Type: research

EVITA 2.0, an updated framework for understanding evidence-based mental health policy agenda-setting: tested and informed by key informant interviews in a multilevel comparative case study
Mental health remains a neglected issue on the global health policy agenda, particularly in low- and middle-income countries (LMIC), and the translation of research evidence into policy and practice is slow. T...
Source: Health Research Policy and Systems - March 10, 2021 Category: International Medicine & Public Health Authors: Nicole Votruba, Jonathan Grant and Graham Thornicroft Tags: Research Source Type: research

UK tightens borders and travel rules as variants spark new alarm
PHE data indicates dominant variant ‘more likely to cause serious illness’ as Grant Shapps warns of threat to reopening on 21 JuneCoronavirus – latest updatesSee all our coronavirus coverageMinisters have moved to tighten Britain ’s borders as new data suggests the Delta coronavirus variant is much more likely to cause serious illness and is circulating more rapidly within schools.With England ’s reopening on 21 June hanging in the balance, the government removedPortugalfrom the green list of countries and added seven more countries to the red list – moves that provoked fury within the travel industry and left ...
Source: Guardian Unlimited Science - June 3, 2021 Category: Science Authors: Peter Walker, Rob Davies, Nicola Davis, Ian Sample and Richard Adams Tags: Coronavirus Grant Shapps Transport policy Medical research UK news Travel & leisure Vaccines and immunisation Politics Science Business Portugal World news Source Type: news

New concepts for the pathogenesis and management of aspirin-exacerbated respiratory disease
Purpose of review The purpose of this review is to provide a comprehensive summary of the current understanding of the pathogenesis of aspirin-exacerbated respiratory disease (AERD), and an update on its management. Recent findings Elevated levels of 15-oxo-eicosatetraenoic acid (15-Oxo-ETE), a newly described metabolite of arachidonic acid, have been identified in nasal polyps of AERD patients. In nasal polyps, activated basophils, and interleukin-5 -receptor-α-positive IL-5Rα+ plasma cells are associated with more severe nasal polyposis in AERD. Alveolar monocyte-derived macrophages and their persistent proi...
Source: Current Opinion in Allergy and Clinical Immunology - December 30, 2021 Category: Allergy & Immunology Tags: MECHANISMS OF ALLERGY AND ADULT ASTHMA: Edited by J. Andrew Grant and Enrico Heffler Source Type: research

Easing the Financial Burden on Upper Limb Amputees: Grants to Support Academics and Quality of Life in North America
Upper limb amputees (ULA's) face several physical and emotional challenges including impairments in physical functioning, alterations in body image and lifestyle, and physical and neuropathic pain.1 One condition includes phantom limb pain, a debilitating infliction that occurs in 50% to 80% of amputees, for which there is no first line treatment2. Along with physical challenges, ULA's face financial problems that total $500,000 over their lifetime3. This does not include loss of job or time off from work – 1/5 of ULA's do not return to work, and those that do typically miss 6 months prior to their return4.
Source: Journal of Plastic, Reconstructive and Aesthetic Surgery - November 22, 2022 Category: Cosmetic Surgery Authors: Eric Bao, Dillan F Villavisanis, Peter J Taub Tags: Correspondence and Communications Source Type: research

A call for culture-centred care: exploring health workers' perspectives of positive care experiences and culturally responsive care provision to Aboriginal women and their infants in mainstream health in South Australia
Aboriginal women and their infants experience significant disadvantage in health outcomes compared to their non-Aboriginal counterparts. Access to timely, effective, and appropriate maternal and child health c...
Source: Health Research Policy and Systems - December 12, 2022 Category: International Medicine & Public Health Authors: Nina Sivertsen, Janiene Deverix, Carolyn Gregoric and Julian Grant Tags: Research Source Type: research

Advancing health through evidence assisted decisions with health policy and systems research program: a qualitative evaluation of a national health research grant management process in the Philippines
Health policy and systems research (HPSR) has influenced Philippine policies, including tobacco control, mental health, and COVID-19. The Department of Health (DOH) Philippines and Philippine Council for Healt...
Source: Health Research Policy and Systems - July 13, 2023 Category: International Medicine & Public Health Authors: Reneepearl Kim Sales, Gladys Kaye Reyes-Ramos, Chiqui de Veyra, Gabrielle Gascon, Vianka Barraca, Gillian Garcia and Maria Eufemia Yap Tags: Research Source Type: research

Mass Media and Body Dissatisfaction: Root Cause or Just a Reminder?
Beliefs in links between "thin ideal" media and body dissatisfaction among women, perhaps even full-blown eating disorders, has been one of the "truisms" or sacred cows of media psychology for at least a generation or two. But just as the media violence/video game debate has spiraled into confusion and chaos, debates about the extent to which media actively cause body dissatisfaction and eating disorders can often leave readers confused and sometimes mislead. It's not at all uncommon to hear it expressed that there are no doubts media ideals cause body dissatisfaction, but we used to hear this with video game violence too....
Source: Science - The Huffington Post - March 18, 2016 Category: Science Source Type: news

Remembered childhood mealtime experiences influence on early childcare and education staff
Appetite. 2023 Aug 16:107003. doi: 10.1016/j.appet.2023.107003. Online ahead of print.ABSTRACTParent feeding styles, behaviors, beliefs, and practices are associated with developing children's eating behaviors. However, many children spend considerable time in childcare; thus, are exposed to child-feeding practices of other adults, e.g., early care and education (ECE) staff. Limited research exists on how and whether current classroom feeding practices of ECE staff associate with their own childhood experiences. The About Feeding Children survey, conducted in 2005, examined self-reported feeding practices and beliefs and p...
Source: Appetite - August 18, 2023 Category: Nutrition Authors: Dong Zhang Taren Swindle Janice Williams Fletcher Madeleine Sigman-Grant Susan L Johnson Source Type: research

My Bipolar Medications & The DUI
I thought I was an old-fashioned kind of girl when I first got married. I thought I wanted to be the one to take care of my man. I wanted to do the cooking, the cleaning, and all the shopping. I wanted to make his doctor appointments and be a stay-at-home mom. I wanted to do all the things I thought women in the 1950s did. Only I wasn’t living in the 1950s. When I married my husband in 1997, I had just graduated cosmetology school and become a stylist at the most upscale salon in our town. I had become a mother at the young age of 17, and I did not want to marry his biological father because I knew I would never have any...
Source: Psych Central - April 3, 2016 Category: Psychiatry Authors: Tosha Maaks Tags: Attention Deficit Disorder Bipolar Caregivers Children and Teens Disorders Family General Medications Parenting Personal Stories Relationships & Love Adhd Attention Deficit Hyperactivity Disorder Driving Under The Influence Irr Source Type: news

Exercise interventions and patient beliefs for people with hip, knee or hip and knee osteoarthritis: a mixed methods review.
CONCLUSIONS: Chronic hip and knee pain affects all domains of people's lives. People's beliefs about chronic pain shape their attitudes and behaviours about how to manage their pain. People are confused about the cause of their pain, and bewildered by its variability and randomness. Without adequate information and advice from healthcare professionals, people do not know what they should and should not do, and, as a consequence, avoid activity for fear of causing harm. Participation in exercise programmes may slightly improve physical function, depression and pain. It may slightly improve self-efficacy and social function,...
Source: Cochrane Database of Systematic Reviews - April 17, 2018 Category: General Medicine Authors: Hurley M, Dickson K, Hallett R, Grant R, Hauari H, Walsh N, Stansfield C, Oliver S Tags: Cochrane Database Syst Rev Source Type: research

Could eating spicy food help you live longer?
ConclusionThis large, well-designed observational study adds to the evidence that certain spices such as chilli pepper may have a beneficial effect on health. But this study does have limitations that need to be taken into account.The study found that people in China who ate a diet that included spicy food (mainly from chilli peppers) at least once a week were less likely to die during the study period than those who ate spicy food less often. These results applied to men and women, even after taking account of factors that affect the risk of death, such as age. The study is part of an ongoing investigation into the effect...
Source: NHS News Feed - August 5, 2015 Category: Consumer Health News Tags: Food/diet Neurology Source Type: news