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Total 21856 results found since Jan 2013.

Next Phase of NIH Preprint Pilot Launching Soon
Last month, the National Library of Medicine (NLM)announced plans to extend its NIH Preprint Pilot in PubMed Central (PMC) and PubMed beyond COVID-19 to encompass all preprints reporting on NIH-funded research. The second phase of the pilot, launching later this month, will include preprints supported by an NIH award, contract, or intramural program and posted to aneligible preprint server on or after January 1, 2023.In preparation for the launch of this second phase, we have updated PMC and PubMed site features to help users of these databases incorporate the increased volume of preprints into their discovery workflows. S...
Source: PubMed Central News - January 10, 2023 Category: Databases & Libraries Source Type: news

Second Phase of the NIH Preprint Pilot Launched
Today, we are pleased to announce the launch of the second phase of the NIH Preprint Pilot with the addition of more than 700 new preprint records to PubMed Central (PMC) and PubMed. This second phase expands the scope of the Pilot to include preprints resulting from all NIH-funded research. Eligible preprints are those acknowledging direct support of an NIH award or authored by NIH staff and posted to bioRxiv, medRxiv, arXiv, or Research Square, on or after January 1, 2023. NLM will automatically include the full text of the preprint (as license terms allow) and associated citation information in PMC and PubMed, respectiv...
Source: PubMed Central News - January 30, 2023 Category: Databases & Libraries Source Type: news

Need for ensuring care for neuro-emergencies —lessons learned from the COVID-19 pandemic
ConclusionsDespite pandemic-related restrictive measures and reallocation of resources, patients with neuro-emergencies should be encouraged to present regardless of the severity of symptoms because deferred presentation may result in adverse outcome. Thus, conservation of critical healthcare resources remains essential in spite of fighting COVID-19.
Source: Acta Neurochirurgica - June 7, 2020 Category: Neurosurgery Source Type: research

Two cases of asymptomatic Teflon granulomas following microvascular decompression mimicking cerebellopontine angle tumours: lessons learnt in the neuro-oncology multidisciplinary team
We present the cases of two patients with asymptomatic Teflon granulomas which were incidentally found years after microvascular decompression and presented to the neuro-oncology multidisciplinary team as possible cerebellopontine angle tumours. Teflon granulomas can be asymptomatic and they can radiologically resemble cerebellopontine angle tumours. It is important that all relevant information is available to the neuro-oncology multidisciplinary team for adequate assessment and appropriate treatment recommendations.PMID:34414772 | DOI:10.1308/rcsann.2021.0030
Source: Annals of the Royal College of Surgeons of England - August 20, 2021 Category: Surgery Authors: A Rojas-Villabona L Magnaye A Jenkins S Surash Source Type: research

Emerging roles for neuropeptides in neuro-immune regulation in amyotrophic lateral sclerosis: Lessons from the superoxide dismutase 1-G93A mouse model
Amyotrophic lateral sclerosis (ALS) is a lethal neurodegenerative disease affecting predominantly motor neurons in cortex, brainstem and spinal cord. While the exact mechanisms causing motor neuron loss are not well understood, neuro-inflammation prominently contributes to disease initiation and progression. The pleiotropic neuro-protective and immune-modulatory neuropeptides, calcitonin gene-related peptide (CGRP) and pituitary adenylate cyclase-activating polypeptide (PACAP) are expressed by subsets of somatomotor and of visceromotor neurons, and their respective receptors found on neurons, astrocytes and microglia.
Source: Journal of Neuroimmunology - October 15, 2014 Category: Allergy & Immunology Authors: Eberhard Weihe, Cornelia Ringer, Burkhard Schütz Tags: 193 Source Type: research

Evolution of a Search: The Use of Dynamic Twitter Searches During Superstorm Sandy
Conclusion The most important lesson learned from Superstorm Sandy was the need for a dynamic and flexible monitoring process and strategy to understand and respond quickly to health needs in the areas impacted by Superstorm Sandy. Search strategies should change as frequently as the unfolding event. The inability to adapt to a changing situation ensures stale and stagnant terminology and search results. Twitter lists and Boolean searches should be used together to maximize situational awareness. The most important information comes from the impacted population, whether news, local government or local citizens. These are t...
Source: PLOS Currents Disasters - September 26, 2014 Category: Global & Universal Authors: Sara Harris Smith Source Type: research

Lessons from a systematic literature search on diagnostic DNA methylation biomarkers for colorectal cancer: how to increase research value and decrease research waste
DiscussionThis systematic literature search revealed that major requirements to develop clinically relevant diagnostic CRC DNA methylation markers are often lacking. To avoid the resulting research waste, clinical needs, intended biomarker use and independent validation should be better considered prior to study design. In addition, improved reporting quality would facilitate meta-analysis, thereby increasing level of evidence and enabling clinical translation.PMID:35584320 | DOI:10.14309/ctg.0000000000000499
Source: Clinical Colorectal Cancer - May 18, 2022 Category: Cancer & Oncology Authors: Zheng Feng Cary J G Oberije Alouisa J P van de Wetering Alexander Koch Kim A D Wouters Nathalie Vaes Ad A M Masclee Beatriz Carvalho Gerrit A Meijer Maurice P Zeegers James G Herman Veerle Melotte Manon van Engeland Kim M Smits Source Type: research

Improve Your Search Skills with Google Search Education
Google recently launched a website with resources teachers and librarians can use to improve student search strategy. The Google Search Education site includes many tools to help improve student search strategy and search results using the Google Search Engine. Lesson plans with practice search questions and activities are provided. For those who are interested in live demonstrations of the search techniques the Live Training area includes videos with sample searches and discussions. While Google Search Eduction was developed for improving student search strategy there are a variety of tools librarians and other educators...
Source: Network News - January 23, 2013 Category: Databases & Libraries Authors: Emily Hurst Tags: General (all entries) Technology Source Type: news

Distributed Adaptive Search in T Cells: Lessons From Ants
There are striking similarities between the strategies ant colonies use to forage for food and immune systems use to search for pathogens. Searchers (ants and cells) use the appropriate combination of random and directed motion, direct and indirect agent-agent interactions, and traversal of physical structures to solve search problems in a variety of environments. An effective immune response requires immune cells to search efficiently and effectively for diverse types of pathogens in different tissues and organs, just as different species of ants have evolved diverse search strategies to forage effectively for a variety o...
Source: Frontiers in Immunology - June 12, 2019 Category: Allergy & Immunology Source Type: research

AAP/AAPOS pediatric neuro-ophthalmology workshop: Avoiding disaster—lessons learned from difficult cases
Difficult Cases, those patients we remember most vividly because of great success or tragic failure, frequently produce a disproportionately intense learning experience. This workshop will present pediatric neuro-ophthalmology case examples that significantly influenced each expert’s approach to a specific problem. The panel members will responds with ideas, differential diagnoses, diagnostic testing and treatment considerations at each stage of the presentations from history to conclusion. Each presenter will provide a short final summary statement with their personal “clinical pearls.”
Source: Journal of AAPOS - February 1, 2013 Category: Opthalmology Authors: Daniel J. Karr, Edward G. Buckley, Jane C. Edmond, Gena Heidary, John MacDonald, Michael R. Siatkowski Tags: AAPOS 2013 Meeting Abstracts Source Type: research