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Nc-13 * cranial radiation encompassing the genu is associated with neuro-psychological sequelae in children: a prospective study of diffusion tensor imaging (dti) and proton mr spectroscopy (mrs)
CONCLUSIONS: The genu is a region with increased susceptibility to injury associated with neuro-psychological sequelae. Efforts should be made to limit radiation dose to this region during treatment planning.
Source: Neuro-Oncology - November 3, 2014 Category: Cancer & Oncology Authors: Redmond, K., Mahone, M., Sair, H., Vannorsdall, T., Terezakis, S., Kleinberg, L., McNutt, T., Wharam, M., Horska, A. Tags: NEURO-COGNITIVE AND FUNCTIONAL OUTCOMES Source Type: research

Carmustine wafer implantation for high-grade gliomas: Evidence-based safety efficacy and practical recommendations from the Neuro-oncology Club of the French Society of Neurosurgery.
Abstract There is a growing body of evidence that carmustine wafer implantation during surgery is an effective therapeutic adjunct to the standard combined radio-chemotherapy regimen using temozolomide in newly diagnosed and recurrent high-grade glioma patient management with a statistically significant survival benefit demonstrated across several randomized clinical trials, as well as prospective and retrospective studies (grade A recommendation). Compelling clinical data also support the safety of carmustine wafer implantation (grade A recommendation) in these patients and suggest that observed adverse events ca...
Source: Neuro-Chirurgie - November 6, 2017 Category: Neurosurgery Authors: Roux A, Caire F, Guyotat J, Menei P, Metellus P, Pallud J, Neuro-Oncology Club of the French Neurosurgical Society Tags: Neurochirurgie Source Type: research

Neuro-Ophthalmic Injuries With Systemic Neurologic Injury or Traumatic Brain Injury in Operation Iraqi Freedom and Operation Enduring Freedom
Background: To analyze the final visual acuity (VA) of neuro-ophthalmologic injuries (NOI) in combat ocular trauma and to study the association of NOI with systemic neurologic injury (SNI) and traumatic brain injury (TBI). Methods: The Walter Reed Ocular Trauma Database was reviewed. Inclusion criteria were any US service member and Department of Defense civilians who suffered NOI, SNI, or TBI in Operation Iraqi Freedom or Operation Enduring Freedom. The primary outcome measure was the rate of poor final VA in patients with an NOI with secondary outcome measures the rate of SNI and TBI. in patients with NOI. Results:...
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Clinical Research: Epidemiology Meets Neuro-Ophthalmology Source Type: research

Conjunctival Biopsy to Diagnose Neurosarcoidosis in Patients with Inflammatory Nervous System Disease of Unknown Etiology (P1.339)
CONCLUSIONS: This study demonstrates that conjunctival biopsy has low diagnostic yield to discover neurosarcoidosis in patients with presumed inflammatory nervous system disease and suggests that alternative diagnostic means should be pursued.Disclosure: Dr. Pichler has nothing to disclose. Dr. Flanagan has nothing to disclose. Dr. Aksamit has nothing to disclose. Dr. Leavitt has nothing to disclose. Dr. Salomao has nothing to disclose. Caridian BCT
Source: Neurology - April 8, 2015 Category: Neurology Authors: Pichler, M., Flanagan, E., Aksamit, A., Leavitt, J., Salomao, D., Keegan, M. Tags: Neuro-ophthalmology/Neuro-otology I Source Type: research

Neuro-Ophthalmic Manifestations of Intracranial Malignancies
Conclusion: Intracranial malignancies can present with neuro-ophthalmic symptoms or signs depending on topographical localization. Specific neuro-ophthalmic presentations are associated with different malignant intracranial tumors. Clinicians should be aware of the common malignant intracranial tumors and their associated clinical presentations in neuro-ophthalmology.
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Trainees' Corner Source Type: research

Diagnostic Error of Neuro-ophthalmologic Conditions: State of the Science
Conclusions: As an emerging field, diagnostic error in neuro-ophthalmology offers rich opportunities for further research and improvement of quality of care.
Source: Journal of Neuro-Ophthalmology - February 25, 2021 Category: Opthalmology Tags: State-of-the-Art Review Source Type: research

Neuro-oncological features of spinal meningiomas: systematic review.
CONCLUSION: WHO grade I predominance was observed among spinal meningiomas, analogous to intracranial meningiomas. SMs predominated in the thoracic spine. Surgery with gross total resection was achieved in the vast majority of cases, resulting in low recurrence and mortality rates. PMID: 31672597 [PubMed - as supplied by publisher]
Source: Neuro-Chirurgie - October 27, 2019 Category: Neurosurgery Authors: Pereira BJA, de Almeida AN, Paiva WS, de Aguiar PHP, Teixeira MJ, Marie SKN Tags: Neurochirurgie Source Type: research

Refinement of formulation and processing steps for pork momo, a traditional meat product of North Eastern India, in the wake of Neuro-cysticercosis
Title: Refinement of formulation and processing steps for pork momo, a traditional meat product of North Eastern India, in the wake of Neuro-cysticercosis Authors: Thomas, R; Naskar, S; Mohan, N H; Sarma, D K Abstract: The mushroom like growth of roadside fast food chains with minimal or no cooking facilities are attributed to the increased incidence of Neuro-cysticercosis in North Eastern Region of India and no documented reports exist regarding the quality characteristics of momos served in these outlets. Hence, a study was undertaken to document different aspects of pork momos sold in the region, viz. cooking cr...
Source: Indian Journal of Traditional Knowledge - December 29, 2015 Category: Science Authors: search Source Type: research

Search for relevant indications for selenium supplementation in thyroid diseases.
Authors: Wojciechowska-Durczynska K, Lewinski A Abstract Selenium plays a significant role in the thyroid function and its deficiency is considered by some authors to be a cause of thyroid disorders. The potential therapeutic influence of selenium supplementation in thyroid disease was investigated in several studies and some results were encouraging, however results were inconsistent and did not allow conclusion to be drawn. For that reason, we have performed a review study on relevance of selenium supplementation in thyroid disease. Till now, there is no strong evidence that selenium supplementation leads to clin...
Source: Neuroendocrinology Letters - September 7, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Obstructive Sleep Apnea in Neuro-Ophthalmology
Conclusions: OSA is associated with many diseases seen in neuro-ophthalmology clinics. More studies are required to assess the real ability of CPAP to reverse pathological changes. Ophthalmologists can screen for undiagnosed OSA in patients presenting with certain eye diseases.
Source: Journal of Neuro-Ophthalmology - August 30, 2019 Category: Opthalmology Tags: State-of-the-Art Review Source Type: research

Publication Rate of Abstracts Presented at the North American Neuro-Ophthalmology Society Annual Meeting From 2008 to 2017
Conclusions: Publication rate of NANOS abstracts is comparable to other conferences in ophthalmology and the neurological sciences. Conference attendees should be aware that more than two-thirds of abstracts fail to be published and publication rates vary widely by type of submission.
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Original Contribution Source Type: research

Impact of Covid-19 Pandemic on Neuro-Oncology Multidisciplinary Tumor Board in the Pre-Vaccine Era: the Normandy experience
CONCLUSION: The pre-vaccination era of the COVID19 pandemic did not impact the activity of neuro-oncology multidisciplinary tumor board in the Normandy region. The possible consequences in terms of public health (excess mortality) due to this tumor location should now be investigated.PMID:36870566 | PMC:PMC9979624 | DOI:10.1016/j.neuchi.2023.101429
Source: Neuro-Chirurgie - March 4, 2023 Category: Neurosurgery Authors: Marine Lacaud Arthur Leclerc Florent Marguet Maxime Faisant Paul Lesueur Houria El Ouazzani Fr édéric Di Fiore Chantal Hanzen Evelyne Emery Olivier Langlois Maxime Fontanilles Source Type: research

Do animal models of brain tumors replicate human peritumoral edema? a systematic literature search
ConclusionNo animal model currently exists that enable the investigation of novel candidates for the treatment of peritumoral brain edema. With current interest in alternative treatments for peritumoral brain edema, there is an unmet need for clinically relevant animal models.
Source: Journal of Neuro-Oncology - February 9, 2023 Category: Cancer & Oncology Source Type: research

Horizontal and Vertical Optokinetic Eye Movements in Macaque Monkeys With Infantile Strabismus: Directional Bias and Crosstalk Eye Movements, Strabismus, Amblyopia, and Neuro-Ophthalmology
Conclusions. With fusion maldevelopment, the OKN pathways retain a nasalward and upward bias. During forward locomotion, optic flow excites temporalward and downward visual motion in each eye. The OKN biases would act in counterbalance. The biases attenuate with emergence of fusion, but may persist and crosstalk when fusion is impeded.
Source: Investigative Ophthalmology - January 13, 2014 Category: Opthalmology Authors: Ghasia, F., Tychsen, L. Tags: Eye Movements, Strabismus, Amblyopia, and Neuro-Ophthalmology Source Type: research

Nimg-64. novel methods for genotype-phenotype correlation in schwannomatosis
In conclusion, we used a highly efficient method for deep, targeted germline sequencing in patients with schwannomatosis. While numbers were small, pain was significantly higher in LZTR1-mutant patients than SMARCB1-mutant patients, which should be considered for development of disease models and targeted therapies. The anatomic limitations of WBMRI will be addressed in future studies by the addition of dedicated neuraxis imaging. Larger studies of schwannomatosis patients are needed to refine these preliminary observations.
Source: Neuro-Oncology - November 6, 2016 Category: Cancer & Oncology Authors: Jordan, J., Smith, M., Merker, V., Cai, W., Harris, G., Bredella, M., Erdin, S., Gusella, J., Plotkin, S. Tags: NEURO-IMAGING Source Type: research