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Source: Experimental and Therapeutic Medicine

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Total 17866 results found since Jan 2013.

Protectin D1 protects against lipopolysaccharide-induced acute lung injury through inhibition of neutrophil infiltration and the formation of neutrophil extracellular traps in lung tissue
In conclusion, PD1 attenuated LPS-induced ALI in mice via inhibition of neutrophil extracellular trap formation in lung tissue. Therefore, PD1 administration may serve to be a new strategy for treating ALI.PMID:34447467 | PMC:PMC8355679 | DOI:10.3892/etm.2021.10508
Source: Experimental and Therapeutic Medicine - August 27, 2021 Category: General Medicine Authors: Zhiyang Wu Luyao Zhang Xiangyang Zhao Zhi Li Haining Lu Chanyuan Bu Rui Wang Xiaofei Wang Tiantian Cai Dawei Wu Source Type: research

Low-activity < sup > 125 < /sup > I implantation into VX < sub > 2 < /sub > tumor rabbits and quantitative evaluation of the precise therapeutic effect
Exp Ther Med. 2021 Dec;22(6):1438. doi: 10.3892/etm.2021.10873. Epub 2021 Oct 12.ABSTRACTThere is still controversy about quantitatively evaluating the therapeutic effect of radioactive low-activity iodine-125 seeds (125I seeds). In the present study, a paired VX2 tumor model in a rabbit hind leg muscle was established, which is virus-induced anaplastic squamous cell carcinoma characterized by hypervascularity, rapid growth and easy propagation in the skeletal muscle. 125I seeds with 0.4 and 0.7 mCi activity were implanted into the left and right legs, respectively, using a radiation treatment planning system under positro...
Source: Experimental and Therapeutic Medicine - November 1, 2021 Category: General Medicine Authors: Zheng Wang Juan Wang Yongyi Yao Feng Wang Qiang Fan Ruifeng Zhao Source Type: research

Role of antioxidants and oxidative stress in the evolution of acute pancreatitis (Review)
Exp Ther Med. 2022 Mar;23(3):197. doi: 10.3892/etm.2022.11120. Epub 2022 Jan 5.ABSTRACTAcute pancreatitis (AP) is a severe disease with a high prevalence and 3 to 15% mortality worldwide, which can represent an important challenge for the physician. Oxidative stress and antioxidants are involved in AP progression. The mechanisms responsible for the onset and progression of AP are still poorly understood. Previous studies have highlighted the important contribution of antioxidants and oxidative stress in AP. The existence of a relationship between oxidative stress and antioxidants in AP is unquestionable, although a more ac...
Source: Experimental and Therapeutic Medicine - February 7, 2022 Category: General Medicine Authors: Vlad P ădureanu Dan Nicolae Florescu Rodica P ădureanu Alice Elena Ghenea Dan Ionu ț Gheonea Carmen Nicoleta Oancea Source Type: research