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The provision of neuro-oncology and glioma neurosurgery during the SARS-CoV-2 pandemic: a single national tertiary centre experience
ConclusionThe provision of neuro-oncological surgery can be safely continued during respiratory illness epidemic or pandemic if a rigorous testing and staffing framework is implemented.
Source: Irish Journal of Medical Science - November 5, 2020 Category: General Medicine Source Type: research

The 21st century epidemic: infections as inductors of neuro-degeneration associated with Alzheimer¿s Disease
Alzheimer?s disease (AD) is a complex disease resulting in neurodegeneration and cognitive impairment. Investigations on environmental factors implicated in AD are scarce and the etiology of the disease remains up to now obscure. The disease?s pathogenesis may be multi-factorial and different etiological factors may converge during aging and induce an activation of brain microglia and macrophages. This microglia priming will result in chronic neuro-inflammation under chronic antigen activation. Infective agents may prime and drive iper-activation of microglia and be partially responsible of the induction of brain inflammat...
Source: Immunity and Aging - December 5, 2014 Category: Geriatrics Authors: Federico LicastroIlaria CarboneElena RaschiElisa Porcellini Source Type: research

Characterization of Idiopathic Intracranial Hypertension (IIH) in Qatar (P5.308)
CONCLUSIONS: Incidence of obesity in our patients was higher than previously reported IIH studies, suggesting a more robust correlation between obesity and IIH in Qatar. Patients presented with larger VF defects, more papilledema reflected by RNFL thickening, and higher CSF opening pressure. Recovery was sub-optimal with persistent field defects in most patients and significant number of RNFL atrophy. These observations indicate a more severe course of IIH in Qatar, which necessitates introducing new therapeutic modalities and disease prevention.Disclosure: Dr. Alkawaz has nothing to disclose. Dr. Barakat has nothing to di...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Alkawaz, M., Barakat, N., AlMannaie, F., Dinkin, M. Tags: Neuro-ophthalmology/Neuro-otology II Source Type: research

Optimal neuro-fuzzy control of hepatitis C virus integrated by genetic algorithm
Hepatitis C blood born virus is a major cause of liver disease that more than three per cent of people in the world is dealing with, and the spread of hepatitis C virus (HCV) infection in different populations is one of the most important issues in epidemiology. In the present study, a new intelligent controller is developed and tested to control the hepatitis C infection in the population which the authors refer to as an optimal adaptive neuro-fuzzy controller. To design the controller, some data is required for training the employed adaptive neuro-fuzzy inference system (ANFIS) which is selected by the genetic algorithm....
Source: IET Systems Biology - August 14, 2018 Category: Biology Source Type: research

Analysis of Cognition, Protection, Psychological, and Job-search Intentions Among Medical and Nonmedical College Students During COVID-19 Epidemic
CONCLUSIONS: The news about COVID-19 piqued the interest of medical students. Nonmedical students had stronger protective behavior than medical students. The COVID-19 outbreak had a significant influence on medical students' lives, studies, and moods. In addition, COVID-19 had a greater impact on the job-search intentions of medical students.PMID:36525353
Source: Alternative Therapies in Health and Medicine - December 16, 2022 Category: Complementary Medicine Authors: Xuan Long Kai Sun Kai Wang Lishuai Shi Limin Cao Tingting Wen Zhonghua Zhou Zhihua Guo Yue Shi Hong Yu Zhen Yu Xiaolian Song Lijin Feng Aihong Mei Source Type: research

High fat diet decreases beneficial effects of estrogen on serotonin-related gene expression in marmosets
This study examined the interaction of E and diet in surgically menopausal nonhuman primates with a 2×2 block design. Marmosets (Callithrix jacchus; n =4/group) were placed on control-low fat diet (LFD; 14%kcal from fat) or high fat diet (HFD; 28%kcal from fat) 1month prior to ovariectomy (Ovx). Empty (placebo) or E-filled Silastic capsules were implanted immediately following Ovx surgery. Treatments extended 6months. The established groups were: placebo+LFD, E+LFD, placebo+HFD, or E+HFD. At necropsy, the brain was flushed with saline and harvested. The midbrain was dissected and a small block containing the dorsal raphe ...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - January 8, 2015 Category: Psychiatry Source Type: research

The risk for problematic opioid use in chronic pain: What can we learn from studies of pain and reward?
Publication date: Available online 1 August 2017Source: Progress in Neuro-Psychopharmacology and Biological PsychiatryAuthor(s): Patrick H. Finan, Bethany Remeniuk, Kelly E. DunnAbstractProblematic prescription opioid use is cited as a primary contributor to the current ‘opioid epidemic’ in the United States, which is characterized by recent rapid increases in individuals seeking treatment for opioid dependence and staggering rates of opioid overdose deaths. Individuals with chronic pain are commonly prescribed opioids to treat pain, and by this mere exposure are at increased risk for the development of problematic opi...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - July 5, 2018 Category: Psychiatry Source Type: research

Members of the same pharmacological family are not alike: Different opioids, different consequences, hope for the opioid crisis?
Publication date: Available online 18 February 2019Source: Progress in Neuro-Psychopharmacology and Biological PsychiatryAuthor(s): Michael A. Emery, Shoshana EitanAbstractPain management is the specialized medical practice of modulating pain perception and thus easing the suffering and improving the life quality of individuals suffering from painful conditions. Since this requires the modulation of the activity of endogenous systems involved in pain perception, and given the large role that the opioidergic system plays in pain perception, opioids are currently the most effective pain treatment available and are likely to ...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - February 18, 2019 Category: Psychiatry Source Type: research

The silent epidemic of chronic pain in older adults
Publication date: Available online 17 April 2019Source: Progress in Neuro-Psychopharmacology and Biological PsychiatryAuthor(s): Anthony F. Domenichiello, Christopher E. RamsdenAbstractChronic pain is highly prevalent among older adults where it is associated with significant suffering, disability, social isolation, and greater costs and burden to health care systems. Pharmaceutical treatment of chronic pain in older adults is usually only partially effective and is often limited by side effects including urinary retention, constipation, sedation, cognitive impairment, and increased risk of falls. Since older adults are un...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - April 18, 2019 Category: Psychiatry Source Type: research

Selected topics in public health - Editorial.
Authors: Abstract In 2019, there were several new epidemics of diseases around the world, which would only be known from old medical books. Conspiracy and antivax movements around the world have raised important issues about public health, its safety, prevention and the media. The importance of public health is increasing more than ever. That is why we are very pleased that we have succeeded in collecting enough quality articles to present a collection of papers this year again. We have a great need for quality data to combat disinformation, hoaxes and lies. But we also have a greater need to deliver this informat...
Source: Neuroendocrinology Letters - December 1, 2019 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research